| Id |
Subject |
Object |
Predicate |
Lexical cue |
ForCovid19 |
Memo |
details |
tao:has_database_id |
| T5 |
19-45 |
Biological |
denotes |
'Renin-Angiotensin' System |
|
|
|
|
| T174 |
52-67 |
Chemical |
denotes |
Candidate Drugs |
drug |
|
|
|
| 3 |
77-94 |
Disease |
denotes |
COVID-19 Diseases |
|
|
|
MESH:D000086382 |
| T200 |
98-108 |
Species |
denotes |
SARS-CoV-2 |
|
|
|
Tax:2697049 |
| T201 |
109-117 |
Disease |
denotes |
infected |
|
|
|
MESH:D007239 |
| 5 |
118-126 |
Species |
denotes |
patients |
|
|
|
Tax:9606 |
| 110 |
128-138 |
Species |
denotes |
SARS-CoV-2 |
|
|
|
Tax:2697049 |
| 111 |
141-149 |
Disease |
denotes |
COVID-19 |
|
|
|
MESH:D000086382 |
| T4 |
158-184 |
Biological |
denotes |
'Renin-Angiotensin' System |
|
|
|
|
| T33 |
200-226 |
Biological |
denotes |
'Renin-Angiotensin' system |
|
|
|
|
| T8 |
228-231 |
Biological |
denotes |
RAS |
|
|
abbreviation |
|
| T34 |
254-292 |
Biological |
denotes |
'Renin-Angiotensin-Aldosterone' system |
|
|
synonym |
|
| 113 |
332-338 |
Species |
denotes |
humans |
|
|
|
Tax:9606 |
| T195 |
350-363 |
Regulation |
denotes |
key regulator |
|
|
|
|
| T1 |
367-372 |
Biological |
denotes |
renal |
|
|
|
|
| T2 |
374-388 |
Biological |
denotes |
cardiovascular |
|
|
|
|
| T194 |
393-406 |
Biological |
denotes |
innate immune |
|
|
|
|
| T193 |
407-415 |
Function |
denotes |
function |
|
|
|
|
| T202 |
425-427 |
Biological |
denotes |
It |
|
|
|
|
| T203 |
439-443 |
Regulation |
denotes |
work |
|
|
|
|
| 114 |
459-468 |
Chemical |
denotes |
vitamin D |
negative |
|
|
MESH:D014807 |
| T197 |
523-531 |
NegativeRegulation |
denotes |
negative |
|
|
|
|
| T196 |
532-549 |
Biological |
denotes |
regulatory factor |
|
|
|
|
| T9 |
557-560 |
Biological |
denotes |
RAS |
|
|
|
|
| T37 |
570-581 |
NegativeRegulation |
denotes |
dysfunction |
|
|
|
|
| T205 |
588-603 |
PositiveRegulation |
denotes |
over-reactivity |
|
|
|
|
| T38 |
608-611 |
Biological |
denotes |
RAS |
|
|
|
|
| T35 |
627-644 |
Disease |
denotes |
hypovitaminosis D |
|
|
|
MESH:D014808 |
| T206 |
656-666 |
Relation |
denotes |
associated |
|
|
|
|
| T39 |
692-697 |
Biological |
denotes |
renal |
|
|
|
|
| T40 |
699-706 |
Biological |
denotes |
cardiac |
|
|
|
|
| T41 |
708-716 |
Biological |
denotes |
vascular |
|
|
|
|
| T43 |
721-736 |
Biological |
denotes |
immune outcomes |
|
|
|
|
| T42 |
728-736 |
Biological |
denotes |
outcomes |
|
|
|
|
| 117 |
763-771 |
Disease |
denotes |
COVID-19 |
|
|
|
MESH:D000086382 |
| 118 |
772-780 |
Species |
denotes |
patients |
|
|
|
Tax:9606 |
| T44 |
796-810 |
Disease |
denotes |
cytokine storm |
|
|
|
http://purl.obolibrary.org/obo/HP_0033041 |
| T208 |
817-826 |
Condition |
denotes |
unopposed |
|
|
|
|
| T45 |
827-854 |
Biological |
denotes |
hyperactive immune reaction |
|
|
|
|
| T207 |
855-865 |
PositiveRegulation |
denotes |
generating |
|
|
|
|
| T48 |
871-887 |
Type |
denotes |
pro-inflammatory |
|
|
|
|
| T47 |
892-909 |
Type |
denotes |
anti-inflammatory |
|
|
|
|
| T46 |
910-918 |
Biological |
denotes |
cytokine |
|
|
|
|
| T204 |
936-942 |
Die |
denotes |
lethal |
|
|
|
|
| 120 |
943-978 |
Disease |
denotes |
acute respiratory distress syndrome |
|
|
|
MESH:D012128 |
| 121 |
997-1007 |
Species |
denotes |
SARS-CoV-2 |
|
|
|
Tax:2697049 |
| 122 |
1039-1047 |
Disease |
denotes |
COVID-19 |
|
|
|
MESH:D000086382 |
| T210 |
1071-1080 |
NegativeRegulation |
denotes |
interfere |
|
|
|
|
| T11 |
1090-1093 |
Biological |
denotes |
RAS |
|
|
|
|
| T211 |
1101-1112 |
Interact |
denotes |
interacting |
|
|
|
|
| T180 |
1122-1144 |
Biological |
denotes |
spike (S) glycoprotein |
|
|
|
|
| T49 |
1172-1203 |
Gene |
denotes |
Angiotensin-Converting Enzyme 2 |
|
|
|
Gene:59272 |
| 123 |
1205-1209 |
Gene |
denotes |
ACE2 |
|
|
|
Gene:59272 |
| T209 |
1236-1245 |
Increase |
denotes |
expressed |
|
|
|
|
| T51 |
1253-1260 |
Localization |
denotes |
surface |
|
|
|
|
| T50 |
1264-1280 |
Biological |
denotes |
epithelial cells |
|
|
|
|
| T52 |
1286-1299 |
Biological |
denotes |
blood vessels |
|
|
|
|
| T53 |
1301-1305 |
Biological |
denotes |
lung |
|
|
|
|
| T54 |
1307-1313 |
Biological |
denotes |
kidney |
|
|
|
|
| T55 |
1315-1328 |
Biological |
denotes |
renal tubules |
|
|
|
|
| T56 |
1331-1340 |
Biological |
denotes |
intestine |
|
|
|
|
| T57 |
1346-1351 |
Biological |
denotes |
heart |
|
|
|
|
| T58 |
1367-1383 |
Biological |
denotes |
cerebral neurons |
|
|
|
|
| T59 |
1388-1394 |
Biological |
denotes |
immune |
|
|
|
|
| T61 |
1388-1404 |
Biological |
denotes |
immune monocytes |
|
|
|
|
| T60 |
1405-1416 |
Biological |
denotes |
macrophages |
|
|
|
|
| 124 |
1435-1445 |
Species |
denotes |
SARS-CoV-2 |
|
|
|
Tax:2697049 |
| 125 |
1454-1462 |
Disease |
denotes |
COVID-19 |
|
|
|
MESH:D000086382 |
| 126 |
1503-1515 |
Disease |
denotes |
hypertension |
|
|
|
MESH:D006973 |
| 127 |
1517-1532 |
Disease |
denotes |
atherosclerosis |
|
|
|
MESH:D050197 |
| 128 |
1534-1544 |
Disease |
denotes |
thrombosis |
|
|
|
MESH:D013927 |
| 129 |
1546-1558 |
Disease |
denotes |
coagulopathy |
|
|
|
MESH:D001778 |
| 130 |
1561-1569 |
Disease |
denotes |
diarrhea |
|
|
|
MESH:D003967 |
| 131 |
1571-1579 |
Disease |
denotes |
glaucoma |
|
|
|
MESH:D005901 |
| 132 |
1581-1588 |
Disease |
denotes |
anosmia |
|
|
|
MESH:D000857 |
| 133 |
1590-1597 |
Disease |
denotes |
ageusia |
|
|
|
MESH:D000370 |
| 134 |
1599-1611 |
Disease |
denotes |
skin lesions |
|
|
|
MESH:D012871 |
| 135 |
1613-1623 |
Disease |
denotes |
dermatitis |
|
|
|
MESH:D003872 |
| 136 |
1626-1679 |
Disease |
denotes |
autoimmune inflammation of the central nervous system |
|
|
|
MESH:D020278 |
| T69 |
1685-1691 |
Disease |
denotes |
damage |
|
|
|
|
| T65 |
1723-1727 |
Biological |
denotes |
lung |
|
|
|
|
| T66 |
1729-1734 |
Biological |
denotes |
heart |
|
|
|
|
| T67 |
1736-1742 |
Biological |
denotes |
kidney |
|
|
|
|
| T68 |
1748-1756 |
Biological |
denotes |
testicle |
|
|
|
|
| T198 |
1779-1786 |
Severity |
denotes |
diffuse |
|
|
|
|
| 137 |
1787-1805 |
Disease |
denotes |
COVID-19 disorders |
|
|
|
MESH:D000086382 |
| T212 |
1830-1843 |
PositiveRegulation |
denotes |
over-reaction |
|
|
|
|
| T12 |
1847-1850 |
Biological |
denotes |
RAS |
|
|
|
|
| 138 |
1854-1873 |
Disease |
denotes |
SARS-CoV-2-infected |
|
|
|
MESH:D000086382 |
| 139 |
1874-1881 |
Species |
denotes |
persons |
|
|
|
Tax:9606 |
| T213 |
1883-1889 |
PositiveRegulation |
denotes |
Such a |
|
|
|
|
| T214 |
1890-1893 |
Biological |
denotes |
RAS |
|
|
|
|
| T70 |
1894-1903 |
PositiveRegulation |
denotes |
imbalance |
|
|
|
|
| T36 |
1929-1946 |
Disease |
denotes |
hypovitaminosis D |
|
|
|
MESH:D014808 |
| T14 |
1964-1967 |
Biological |
denotes |
RAS |
|
|
|
|
| 141 |
1993-2001 |
Disease |
denotes |
COVID-19 |
|
|
|
MESH:D000086382 |
| T219 |
2021-2040 |
Target |
denotes |
selective targeting |
|
|
|
|
| T217 |
2044-2060 |
Biological |
denotes |
key component(s) |
|
|
|
|
| T218 |
2064-2075 |
Biological |
denotes |
this system |
|
|
|
|
| T216 |
2100-2105 |
Therapy |
denotes |
treat |
|
|
|
|
| T71 |
2106-2129 |
Disease |
denotes |
RAS-dependent disorders |
|
|
|
|
| 142 |
2131-2149 |
Disease |
denotes |
COVID-19 Disorders |
|
|
|
MESH:D000086382 |
| T6 |
2151-2177 |
Biological |
denotes |
'Renin-Angiotensin' System |
|
|
|
|
| T7 |
2179-2182 |
Biological |
denotes |
RAS |
|
|
|
|
| T74 |
2186-2227 |
Biological |
denotes |
Counter-regulatory RAS In the RAS pathway |
|
|
|
|
| T75 |
2237-2242 |
Biological |
denotes |
Renin |
|
|
|
|
| T77 |
2244-2250 |
Biological |
denotes |
kidney |
|
|
|
|
| T221 |
2252-2259 |
Cleave |
denotes |
cleaves |
|
|
|
|
| T76 |
2260-2275 |
Biological |
denotes |
Angiotensinogen |
|
|
|
|
| T78 |
2277-2282 |
Biological |
denotes |
liver |
|
|
|
|
| T222 |
2287-2291 |
Produce |
denotes |
give |
|
|
|
|
| 143 |
2292-2305 |
Gene |
denotes |
Angiotensin I |
peptide |
|
|
Gene:183 |
| T181 |
2320-2330 |
Biological |
denotes |
DRVYIHPFHL |
peptide |
|
|
|
| T220 |
2337-2343 |
Biological |
denotes |
latter |
|
|
|
|
| T223 |
2347-2354 |
Cleave |
denotes |
cleaved |
|
|
|
|
| 144 |
2362-2391 |
Gene |
denotes |
Angiotensin-Converting Enzyme |
|
|
|
Gene:1636 |
| 145 |
2393-2396 |
Gene |
denotes |
ACE |
|
|
|
Gene:1636 |
| T224 |
2401-2408 |
Produce |
denotes |
produce |
|
|
|
|
| 146 |
2409-2423 |
Gene |
denotes |
Angiotensin II |
peptide |
|
|
Gene:183 |
| T182 |
2438-2446 |
Biological |
denotes |
DRVYIHPF |
peptide |
|
|
|
| T225 |
2462-2471 |
Substrate |
denotes |
substrate |
|
|
|
|
| 147 |
2475-2479 |
Gene |
denotes |
ACE2 |
|
|
|
Gene:59272 |
| T227 |
2481-2500 |
Biological |
denotes |
SARS-CoV-2 receptor |
|
|
|
|
| T226 |
2506-2516 |
Target |
denotes |
key player |
|
|
|
|
| T18 |
2524-2527 |
Biological |
denotes |
RAS |
|
|
|
|
| T228 |
2542-2549 |
Target |
denotes |
targets |
|
|
|
|
| 149 |
2553-2567 |
Gene |
denotes |
Angiotensin II |
|
|
|
Gene:183 |
| T232 |
2576-2591 |
Function |
denotes |
vasoconstrictor |
|
|
|
|
| T81 |
2592-2598 |
Gene |
denotes |
type 1 |
|
|
|
Gene:185 |
| 150 |
2600-2604 |
Gene |
denotes |
AT1R |
|
|
|
Gene:185 |
| T233 |
2610-2623 |
Function |
denotes |
vasodilatator |
|
|
|
|
| T89 |
2624-2630 |
Gene |
denotes |
type 2 |
|
|
|
Gene:186 |
| T86 |
2632-2636 |
Gene |
denotes |
AT2R |
|
|
|
Gene:186 |
| T83 |
2638-2661 |
Gene |
denotes |
Angiotensin II receptor |
|
|
|
Gene:185 |
| T87 |
2638-2661 |
Gene |
denotes |
Angiotensin II receptor |
|
|
|
Gene:186 |
| 152 |
2664-2668 |
Gene |
denotes |
AT1R |
|
|
|
Gene:185 |
| T229 |
2672-2681 |
Increase |
denotes |
expressed |
|
|
|
|
| T93 |
2689-2696 |
Localization |
denotes |
surface |
|
|
|
|
| T90 |
2700-2709 |
Biological |
denotes |
monocytes |
|
|
|
|
| T91 |
2710-2721 |
Biological |
denotes |
macrophages |
|
|
|
|
| T92 |
2726-2733 |
Biological |
denotes |
T-cells |
|
|
|
|
| T19 |
2750-2753 |
Biological |
denotes |
RAS |
|
|
|
|
| T231 |
2754-2758 |
Target |
denotes |
acts |
|
|
|
|
| T94 |
2762-2777 |
Biological |
denotes |
innate immunity |
|
|
|
|
| T230 |
2781-2785 |
Species |
denotes |
host |
|
|
|
|
| T237 |
2793-2800 |
Cleave |
denotes |
cleaved |
|
|
|
|
| 153 |
2804-2808 |
Gene |
denotes |
ACE2 |
|
|
|
Gene:59272 |
| 154 |
2810-2824 |
Gene |
denotes |
Angiotensin II |
|
|
|
Gene:183 |
| T238 |
2825-2830 |
Produce |
denotes |
gives |
|
|
|
|
| T95 |
2831-2846 |
Gene |
denotes |
Angiotensin 1-7 |
peptide |
|
|
Gene:183|MESH:C118790 |
| T183 |
2861-2868 |
Biological |
denotes |
DRVYIHP |
peptide |
|
|
|
| T240 |
2871-2880 |
Target |
denotes |
targeting |
|
|
|
|
| T239 |
2885-2898 |
Function |
denotes |
vasodilatator |
|
|
|
|
| 156 |
2928-2932 |
Gene |
denotes |
MasR |
|
|
|
Gene:116511 |
| T234 |
2935-2950 |
Gene |
denotes |
Angiotensin 1-7 |
peptide |
|
|
Gene:183|MESH:C118790 |
| T241 |
2966-2977 |
Cleave |
denotes |
transformed |
|
|
|
|
| T242 |
2978-2980 |
Produce |
denotes |
to |
|
|
|
|
| 158 |
2981-2991 |
Chemical |
denotes |
Alamandine |
peptide |
|
|
MESH:C581752 |
| T184 |
3006-3013 |
Biological |
denotes |
ARVYIHP |
peptide |
|
|
|
| T97 |
3021-3044 |
Biological |
denotes |
aspartate decarboxylase |
|
|
|
MESH:C019747 |
| 161 |
3046-3056 |
Chemical |
denotes |
Alamandine |
peptide |
|
|
MESH:C581752 |
| T244 |
3063-3067 |
Bind |
denotes |
bind |
|
|
|
|
| T243 |
3075-3088 |
Function |
denotes |
vasodilatator |
|
|
|
|
| 162 |
3089-3136 |
Gene |
denotes |
Mas-related G protein-coupled receptor member D |
|
|
|
Gene:116512 |
| 163 |
3138-3142 |
Gene |
denotes |
MRGD |
|
|
|
Gene:116512 |
| T245 |
3149-3158 |
PositiveRegulation |
denotes |
promoting |
|
|
|
|
| T246 |
3171-3199 |
Result |
denotes |
Angiotensin 1-7-like effects |
|
|
|
|
| 165 |
3201-3215 |
Gene |
denotes |
Angiotensin II |
|
|
|
Gene:183 |
| T247 |
3220-3227 |
Produce |
denotes |
produce |
|
|
|
|
| T108 |
3228-3241 |
Biological |
denotes |
Angiotensin A |
peptide |
|
|
MESH:C516880 |
| T185 |
3256-3264 |
Biological |
denotes |
ARVYIHPF |
peptide |
|
|
|
| T248 |
3266-3269 |
Change |
denotes |
via |
|
|
|
|
| T99 |
3273-3296 |
Biological |
denotes |
aspartate decarboxylase |
|
|
|
MESH:C019747 |
| 168 |
3302-3312 |
Chemical |
denotes |
Alamandine |
peptide |
|
|
MESH:C581752 |
| T249 |
3313-3316 |
Produce |
denotes |
via |
|
|
|
|
| 169 |
3331-3335 |
Gene |
denotes |
ACE2 |
|
|
|
Gene:59272 |
| T250 |
3336-3344 |
Cleave |
denotes |
cleavage |
|
|
|
|
| 170 |
3346-3350 |
Gene |
denotes |
ACE2 |
|
|
|
Gene:59272 |
| T251 |
3360-3366 |
Cleave |
denotes |
cleave |
|
|
|
|
| 171 |
3367-3380 |
Gene |
denotes |
Angiotensin I |
|
|
|
Gene:183 |
| T252 |
3384-3388 |
Produce |
denotes |
form |
|
|
|
|
| T112 |
3389-3404 |
Gene |
denotes |
Angiotensin 1-9 |
peptide |
|
|
Gene:183|MESH:C506331 |
| T186 |
3419-3428 |
Biological |
denotes |
DRVYIHPFH |
peptide |
|
|
|
| T253 |
3437-3444 |
Target |
denotes |
targets |
|
|
|
|
| T105 |
3445-3449 |
Gene |
denotes |
AT2R |
|
|
|
Gene:186 |
| T20 |
3458-3469 |
Biological |
denotes |
RAS pathway |
|
|
|
|
| T116 |
3505-3520 |
Gene |
denotes |
Angiotensin III |
peptide |
|
|
Gene:183|MESH:D000805 |
| T187 |
3535-3542 |
Biological |
denotes |
RVYIHPF |
peptide |
|
|
|
| T120 |
3548-3562 |
Gene |
denotes |
Angiotensin IV |
peptide |
|
|
Gene:183|MESH:C496150 |
| T188 |
3577-3583 |
Biological |
denotes |
VYIHPF |
peptide |
|
|
|
| T254 |
3594-3603 |
Target |
denotes |
targeting |
|
|
|
|
| T255 |
3594-3603 |
Target |
denotes |
targeting |
|
|
|
|
| 174 |
3608-3612 |
Gene |
denotes |
AT1R |
|
|
|
Gene:185 |
| T124 |
3631-3635 |
Biological |
denotes |
AT4R |
|
May be MESH:C090830? |
|
|
| T21 |
3695-3698 |
Biological |
denotes |
RAS |
|
|
|
|
| T130 |
3700-3711 |
Gene |
denotes |
Angiotensin |
peptide |
|
|
Gene:183 |
| T132 |
3713-3714 |
Gene |
denotes |
I |
peptide |
|
|
Gene:183 |
| T129 |
3719-3721 |
Gene |
denotes |
II |
peptide |
|
|
Gene:183 |
| T256 |
3723-3728 |
Negative |
denotes |
aside |
|
|
|
|
| T123 |
3729-3744 |
Gene |
denotes |
Angiotensin III |
peptide|exclude |
|
|
Gene:183|MESH:D000805 |
| T199 |
3758-3771 |
Target |
denotes |
central roles |
|
|
|
|
| T22 |
3791-3794 |
Biological |
denotes |
RAS |
|
|
|
|
| 177 |
3833-3841 |
Disease |
denotes |
COVID-19 |
|
|
|
MESH:D000086382 |
| T23 |
3884-3904 |
NegativeRegulation |
denotes |
'counter-regulatory' |
|
|
|
|
| T258 |
3905-3908 |
Biological |
denotes |
RAS |
|
|
|
|
| T260 |
3923-3931 |
Regulation |
denotes |
modulate |
|
|
|
|
| T257 |
3932-3938 |
Biological |
denotes |
system |
|
|
|
|
| T259 |
3939-3950 |
Biological |
denotes |
homeostasis |
|
|
|
|
| T235 |
3965-3980 |
Gene |
denotes |
Angiotensin 1-7 |
peptide |
|
|
Gene:183|MESH:C118790 |
| T114 |
3982-3997 |
Gene |
denotes |
Angiotensin 1-9 |
peptide |
|
|
Gene:183|MESH:C506331 |
| 180 |
3999-4009 |
Chemical |
denotes |
Alamandine |
peptide |
|
|
MESH:C581752 |
| T109 |
4011-4024 |
Biological |
denotes |
Angiotensin A |
peptide |
|
|
MESH:C516880 |
| T121 |
4030-4044 |
Gene |
denotes |
Angiotensin IV |
peptide |
|
|
Gene:183 |
| T261 |
4056-4065 |
Target |
denotes |
targeting |
|
|
|
|
| T262 |
4056-4065 |
Target |
denotes |
targeting |
|
|
|
|
| T263 |
4056-4065 |
Target |
denotes |
targeting |
|
|
|
|
| T264 |
4056-4065 |
Target |
denotes |
targeting |
|
|
|
|
| T265 |
4056-4065 |
Target |
denotes |
targeting |
|
|
|
|
| 181 |
4070-4074 |
Gene |
denotes |
MasR |
|
|
|
Gene:116511 |
| T106 |
4076-4080 |
Gene |
denotes |
AT2R |
|
|
|
Gene:186 |
| 182 |
4082-4086 |
Gene |
denotes |
MRGD |
|
|
|
Gene:116512 |
| 183 |
4088-4092 |
Gene |
denotes |
ACE2 |
|
|
|
Gene:59272 |
| T143 |
4097-4101 |
Biological |
denotes |
AT4R |
|
May be MESH:C090830? |
|
|
| T266 |
4102-4115 |
Function |
denotes |
vasodilatator |
|
|
|
|
| T267 |
4141-4155 |
Biological |
denotes |
These peptides |
|
|
|
|
| T148 |
4178-4194 |
Function |
denotes |
cardioprotective |
|
|
|
|
| T149 |
4196-4206 |
Function |
denotes |
vasoactive |
|
|
|
|
| T150 |
4208-4225 |
Function |
denotes |
anti-hypertensive |
|
|
|
|
| T151 |
4228-4245 |
Function |
denotes |
anti-hypertrophic |
|
|
|
|
| T153 |
4253-4270 |
Function |
denotes |
anti-inflammatory |
|
|
|
|
| T268 |
4288-4321 |
Biological |
denotes |
Such naturally-produced molecules |
|
|
|
|
| T24 |
4329-4332 |
Biological |
denotes |
RAS |
|
|
|
|
| T269 |
4349-4359 |
NegativeRegulation |
denotes |
counteract |
|
|
|
|
| 186 |
4364-4374 |
Species |
denotes |
SARS-CoV-2 |
|
|
|
Tax:2697049 |
| T270 |
4383-4398 |
PositiveRegulation |
denotes |
over-activation |
|
|
|
|
| T25 |
4402-4405 |
Biological |
denotes |
RAS |
|
|
|
|
| T271 |
4410-4417 |
BecomeReduce |
denotes |
reverse |
|
|
|
|
| 187 |
4450-4458 |
Disease |
denotes |
COVID-19 |
|
|
|
MESH:D000086382 |
| T154 |
4518-4532 |
Chemical |
denotes |
RAS inhibitors |
inhibitor |
|
|
|
| T189 |
4548-4556 |
Severity |
denotes |
severity |
|
|
|
|
| 188 |
4560-4575 |
Disease |
denotes |
viral infection |
|
|
|
MESH:D001102 |
| 189 |
4580-4589 |
Die |
denotes |
mortality |
|
|
|
MESH:D003643 |
| 190 |
4593-4601 |
Disease |
denotes |
COVID-19 |
|
|
|
MESH:D000086382 |
| 191 |
4602-4610 |
Species |
denotes |
patients |
|
|
|
Tax:9606 |
| T27 |
4632-4644 |
Chemical |
denotes |
RAS blockers |
inhibitor|drug |
|
|
|
| 192 |
4668-4676 |
Disease |
denotes |
COVID-19 |
|
|
|
MESH:D000086382 |
| T28 |
4711-4725 |
Chemical |
denotes |
RAS inhibitors |
inhibitor|drug |
|
|
|
| T275 |
4733-4740 |
Prevent |
denotes |
prevent |
|
|
|
|
| T156 |
4745-4759 |
Disease |
denotes |
cytokine storm |
|
|
|
http://purl.obolibrary.org/obo/HP_0033041 |
| T29 |
4763-4766 |
Biological |
denotes |
RAS |
|
|
|
|
| T274 |
4782-4789 |
Regulation |
denotes |
control |
|
|
|
|
| T273 |
4794-4801 |
Increase |
denotes |
release |
|
|
|
|
| T157 |
4805-4831 |
Biological |
denotes |
pro-inflammatory cytokines |
|
|
|
|
| 193 |
4856-4864 |
Disease |
denotes |
COVID-19 |
|
|
|
MESH:D000086382 |
| 194 |
4878-4897 |
Disease |
denotes |
SARS-CoV-2-infected |
|
|
|
MESH:D000086382 |
| 195 |
4898-4904 |
Species |
denotes |
humans |
|
|
|
Tax:9606 |
| T277 |
4905-4911 |
Depend |
denotes |
depend |
|
|
|
|
| T30 |
4919-4922 |
Biological |
denotes |
RAS |
|
|
|
|
| T276 |
4923-4935 |
PositiveRegulation |
denotes |
over-reacted |
|
|
|
|
| 196 |
4944-4948 |
Gene |
denotes |
ACE2 |
|
|
|
Gene:59272 |
| T191 |
4949-4958 |
Depend |
denotes |
dependent |
|
|
|
|
| 197 |
4960-4975 |
Disease |
denotes |
viral infection |
|
|
|
MESH:D001102 |
| T158 |
4980-5000 |
Disease |
denotes |
vitamin D deficiency |
|
|
|
http://purl.obolibrary.org/obo/HP_0100512 |
| 199 |
5027-5035 |
Disease |
denotes |
COVID-19 |
|
|
|
MESH:D000086382 |
| T278 |
5036-5045 |
Therapy |
denotes |
treatment |
|
|
|
|
| T281 |
5058-5064 |
Target |
denotes |
target |
|
|
|
|
| T280 |
5065-5068 |
Biological |
denotes |
RAS |
|
|
|
|
| T279 |
5075-5116 |
Chemical |
denotes |
specific candidate chemotherapeutic drugs |
drug |
|
|
|
| T282 |
5122-5140 |
Chemical |
denotes |
proposed molecules |
|
|
|
|
| T159 |
5154-5168 |
Chemical |
denotes |
ACE inhibitors |
inhibitor|drug |
|
|
|
| T285 |
5173-5180 |
Prevent |
denotes |
prevent |
|
|
|
|
| T284 |
5185-5195 |
Produce |
denotes |
production |
|
|
|
|
| 201 |
5199-5213 |
Gene |
denotes |
Angiotensin II |
peptide |
|
|
Gene:183 |
| 202 |
5219-5232 |
Gene |
denotes |
Angiotensin I |
peptide |
|
|
Gene:183 |
| T161 |
5239-5247 |
Chemical |
denotes |
blockers |
inhibitor|drug |
|
|
|
| T163 |
5248-5259 |
Chemical |
denotes |
antagonists |
inhibitor|drug |
|
|
|
| T283 |
5263-5267 |
Gene |
denotes |
AT1R |
|
|
|
Gene:185 |
| 204 |
5276-5284 |
Chemical |
denotes |
Losartan |
inhibitor|drug |
|
|
MESH:D019808 |
| T164 |
5276-5284 |
Chemical |
denotes |
Losartan |
inhibitor |
|
|
|
| T160 |
5289-5300 |
Chemical |
denotes |
derivatives |
inhibitor |
|
|
|
| T166 |
5302-5313 |
Recombinant |
denotes |
Recombinant |
|
|
|
|
| T287 |
5314-5318 |
Gene |
denotes |
ACE2 |
|
|
|
Gene:59272 |
| T291 |
5367-5372 |
Chemical |
denotes |
decoy |
decoy |
|
|
|
| T292 |
5397-5408 |
Condition |
denotes |
competitive |
|
|
|
|
| T290 |
5409-5416 |
Bind |
denotes |
binding |
|
|
|
|
| T288 |
5424-5446 |
Biological |
denotes |
spike (S) glycoprotein |
|
|
|
|
| 206 |
5450-5460 |
Species |
denotes |
SARS-CoV-2 |
|
|
|
Tax:2697049 |
| T173 |
5492-5523 |
Chemical |
denotes |
natural candidate peptide drugs |
drug |
|
|
|
| T293 |
5544-5562 |
NegativeRegulation |
denotes |
counter-regulatory |
|
|
|
|
| T32 |
5564-5567 |
Biological |
denotes |
RAS |
|
|
|
|
| T236 |
5574-5589 |
Gene |
denotes |
Angiotensin 1-7 |
peptide|drug |
|
|
Gene:183|MESH:C118790 |
| T115 |
5591-5606 |
Gene |
denotes |
Angiotensin 1-9 |
peptide |
|
|
Gene:183|MESH:C506331 |
| 209 |
5608-5618 |
Chemical |
denotes |
Alamandine |
peptide |
|
|
MESH:C581752 |
| T110 |
5620-5633 |
Biological |
denotes |
Angiotensin A |
peptide |
|
|
MESH:C516880 |
| T122 |
5641-5655 |
Gene |
denotes |
Angiotensin IV |
peptide |
|
|
Gene:183 |
| T294 |
5659-5664 |
Therapy |
denotes |
treat |
|
|
|
|
| 210 |
5665-5683 |
Disease |
denotes |
COVID-19 disorders |
|
|
|
MESH:D000086382 |
| T192 |
5689-5707 |
Target |
denotes |
targeted receptors |
|
|
|
|
| 211 |
5722-5726 |
Gene |
denotes |
MasR |
|
|
|
Gene:116511 |
| T107 |
5728-5732 |
Gene |
denotes |
AT2R |
|
|
|
Gene:186 |
| 212 |
5734-5738 |
Gene |
denotes |
MRGD |
|
|
|
Gene:116512 |
| 213 |
5740-5744 |
Gene |
denotes |
ACE2 |
|
|
|
Gene:59272 |
| T144 |
5749-5753 |
Biological |
denotes |
AT4R |
|
May be MESH:C090830? |
|
|
| R10 |
T55 |
T51 |
of_a |
renal tubules,surface |
| R101 |
T8 |
T33 |
abbreviation |
RAS,'Renin-Angiotensin' system |
| R102 |
T34 |
T33 |
synonym |
'Renin-Angiotensin-Aldosterone' system,'Renin-Angiotensin' system |
| R103 |
T195 |
113 |
in |
key regulator,humans |
| R104 |
T9 |
T196 |
of_a |
RAS,regulatory factor |
| R105 |
T197 |
T196 |
is_a |
negative,regulatory factor |
| R106 |
T196 |
114 |
is_a |
regulatory factor,vitamin D |
| R107 |
T202 |
T33 |
coreference |
It,'Renin-Angiotensin' system |
| R108 |
114 |
T203 |
with |
vitamin D,work |
| R109 |
T203 |
T195 |
coreference |
work,key regulator |
| R11 |
T56 |
T51 |
of_a |
intestine,surface |
| R110 |
T202 |
T203 |
is_a |
It,work |
| R111 |
120 |
T204 |
has_status |
acute respiratory distress syndrome,lethal |
| R112 |
T47 |
T46 |
of_a |
anti-inflammatory,cytokine |
| R113 |
117 |
118 |
has_a |
COVID-19,patients |
| R114 |
T205 |
T38 |
is_a |
over-reactivity,RAS |
| R115 |
T38 |
T206 |
relates |
RAS,associated |
| R116 |
T43 |
T206 |
cause_of |
immune outcomes,associated |
| R117 |
T42 |
T206 |
cause_of |
outcomes,associated |
| R118 |
T35 |
T206 |
with |
hypovitaminosis D,associated |
| R119 |
T44 |
T206 |
cause_of |
cytokine storm,associated |
| R12 |
T57 |
T51 |
of_a |
heart,surface |
| R120 |
T45 |
T208 |
has_status |
hyperactive immune reaction,unopposed |
| R121 |
T45 |
T44 |
is_a |
hyperactive immune reaction,cytokine storm |
| R122 |
120 |
T206 |
cause_of |
acute respiratory distress syndrome,associated |
| R123 |
T45 |
T207 |
relates |
hyperactive immune reaction,generating |
| R124 |
T46 |
T207 |
cause_of |
cytokine,generating |
| R125 |
123 |
T49 |
abbreviation |
ACE2,Angiotensin-Converting Enzyme 2 |
| R127 |
T51 |
T209 |
at |
surface,expressed |
| R128 |
T209 |
T49 |
is_a |
expressed,Angiotensin-Converting Enzyme 2 |
| R129 |
T58 |
T209 |
at |
cerebral neurons,expressed |
| R130 |
T61 |
T209 |
at |
immune monocytes,expressed |
| R131 |
T59 |
T209 |
at |
immune,expressed |
| R132 |
121 |
122 |
by |
SARS-CoV-2,COVID-19 |
| R133 |
T180 |
121 |
of_a |
spike (S) glycoprotein,SARS-CoV-2 |
| R135 |
T210 |
T11 |
is_a |
interfere,RAS |
| R137 |
T211 |
T210 |
cause_of |
interacting,interfere |
| R138 |
T180 |
T211 |
is_a |
spike (S) glycoprotein,interacting |
| R140 |
124 |
125 |
by |
SARS-CoV-2,COVID-19 |
| R141 |
126 |
125 |
is_a |
hypertension,COVID-19 |
| R142 |
127 |
125 |
is_a |
atherosclerosis,COVID-19 |
| R143 |
128 |
125 |
is_a |
thrombosis,COVID-19 |
| R144 |
129 |
125 |
is_a |
coagulopathy,COVID-19 |
| R145 |
130 |
125 |
is_a |
diarrhea,COVID-19 |
| R146 |
131 |
125 |
is_a |
glaucoma,COVID-19 |
| R147 |
132 |
125 |
is_a |
anosmia,COVID-19 |
| R148 |
133 |
125 |
is_a |
ageusia,COVID-19 |
| R149 |
134 |
125 |
is_a |
skin lesions,COVID-19 |
| R150 |
135 |
125 |
is_a |
dermatitis,COVID-19 |
| R151 |
136 |
125 |
is_a |
autoimmune inflammation of the central nervous system,COVID-19 |
| R152 |
T69 |
125 |
is_a |
damage,COVID-19 |
| R153 |
T198 |
137 |
of_a |
diffuse,COVID-19 disorders |
| R154 |
T212 |
T12 |
is_a |
over-reaction,RAS |
| R155 |
138 |
139 |
by |
SARS-CoV-2-infected,persons |
| R156 |
137 |
T212 |
relates |
COVID-19 disorders,over-reaction |
| R157 |
139 |
T12 |
in |
persons,RAS |
| R158 |
T70 |
T212 |
coreference |
imbalance,over-reaction |
| R160 |
T213 |
T70 |
- |
Such a,imbalance |
| R161 |
T70 |
T214 |
is_a |
imbalance,RAS |
| R162 |
T36 |
T70 |
relates |
hypovitaminosis D,imbalance |
| R163 |
T218 |
T14 |
coreference |
this system,RAS |
| R164 |
T218 |
T217 |
of_a |
this system,key component(s) |
| R165 |
T71 |
T216 |
of_a |
RAS-dependent disorders,treat |
| R166 |
T219 |
T217 |
is_a |
selective targeting,key component(s) |
| R167 |
T216 |
T219 |
for |
treat,selective targeting |
| R168 |
T7 |
T6 |
abbreviation |
RAS,'Renin-Angiotensin' System |
| R169 |
T77 |
T75 |
in |
kidney,Renin |
| R170 |
T78 |
T76 |
in |
liver,Angiotensinogen |
| R171 |
145 |
144 |
abbreviation |
ACE,Angiotensin-Converting Enzyme |
| R172 |
T75 |
T221 |
is_a |
Renin,cleaves |
| R173 |
T76 |
T222 |
is_a |
Angiotensinogen,give |
| R174 |
T221 |
T76 |
of_a |
cleaves,Angiotensinogen |
| R175 |
T222 |
143 |
of_a |
give,Angiotensin I |
| R176 |
T181 |
143 |
is_a |
DRVYIHPFHL,Angiotensin I |
| R177 |
T220 |
143 |
coreference |
latter,Angiotensin I |
| R178 |
T220 |
T224 |
is_a |
latter,produce |
| R179 |
144 |
T223 |
is_a |
Angiotensin-Converting Enzyme,cleaved |
| R180 |
T223 |
T220 |
of_a |
cleaved,latter |
| R182 |
T224 |
146 |
of_a |
produce,Angiotensin II |
| R183 |
T182 |
146 |
is_a |
DRVYIHPF,Angiotensin II |
| R184 |
146 |
T226 |
is_a |
Angiotensin II,key player |
| R185 |
T18 |
T226 |
of_a |
RAS,key player |
| R186 |
146 |
T225 |
is_a |
Angiotensin II,substrate |
| R187 |
147 |
T225 |
of_a |
ACE2,substrate |
| R188 |
147 |
T227 |
is_a |
ACE2,SARS-CoV-2 receptor |
| R189 |
150 |
T83 |
abbreviation |
AT1R,Angiotensin II receptor |
| R190 |
T86 |
T87 |
abbreviation |
AT2R,Angiotensin II receptor |
| R191 |
T90 |
T93 |
of_a |
monocytes,surface |
| R192 |
T91 |
T93 |
of_a |
macrophages,surface |
| R193 |
149 |
T228 |
of_a |
Angiotensin II,targets |
| R194 |
T228 |
T81 |
is_a |
targets,type 1 |
| R195 |
T228 |
T89 |
is_a |
targets,type 2 |
| R196 |
T229 |
152 |
is_a |
expressed,AT1R |
| R197 |
T93 |
T229 |
at |
surface,expressed |
| R198 |
T50 |
T51 |
of_a |
epithelial cells,surface |
| R199 |
T92 |
T229 |
at |
T-cells,expressed |
| R200 |
T19 |
T231 |
is_a |
RAS,acts |
| R201 |
T94 |
T231 |
of_a |
innate immunity,acts |
| R202 |
T230 |
T231 |
in |
host,acts |
| R203 |
T81 |
T232 |
has_a |
type 1,vasoconstrictor |
| R204 |
T89 |
T233 |
has_a |
type 2,vasodilatator |
| R205 |
T183 |
T95 |
is_a |
DRVYIHP,Angiotensin 1-7 |
| R206 |
T184 |
158 |
is_a |
ARVYIHP,Alamandine |
| R207 |
T185 |
T108 |
is_a |
ARVYIHPF,Angiotensin A |
| R208 |
T186 |
T112 |
is_a |
DRVYIHPFH,Angiotensin 1-9 |
| R209 |
T187 |
T116 |
is_a |
RVYIHPF,Angiotensin III |
| R21 |
T59 |
T60 |
- |
immune,macrophages |
| R210 |
T188 |
T120 |
is_a |
VYIHPF,Angiotensin IV |
| R211 |
153 |
T237 |
is_a |
ACE2,cleaved |
| R212 |
T237 |
154 |
of_a |
cleaved,Angiotensin II |
| R213 |
154 |
T238 |
is_a |
Angiotensin II,gives |
| R214 |
T238 |
T95 |
of_a |
gives,Angiotensin 1-7 |
| R215 |
156 |
T239 |
has_a |
MasR,vasodilatator |
| R216 |
T95 |
T240 |
is_a |
Angiotensin 1-7,targeting |
| R217 |
T240 |
156 |
is_a |
targeting,MasR |
| R218 |
T95 |
T240 |
of_a |
Angiotensin 1-7,targeting |
| R219 |
T97 |
T241 |
is_a |
aspartate decarboxylase,transformed |
| R220 |
T241 |
T234 |
of_a |
transformed,Angiotensin 1-7 |
| R221 |
T234 |
T242 |
is_a |
Angiotensin 1-7,to |
| R222 |
T242 |
158 |
of_a |
to,Alamandine |
| R223 |
T243 |
162 |
has_a |
vasodilatator,Mas-related G protein-coupled receptor member D |
| R224 |
163 |
162 |
abbreviation |
MRGD,Mas-related G protein-coupled receptor member D |
| R225 |
161 |
T244 |
is_a |
Alamandine,bind |
| R226 |
T244 |
162 |
to |
bind,Mas-related G protein-coupled receptor member D |
| R227 |
T245 |
T246 |
is_a |
promoting,Angiotensin 1-7-like effects |
| R228 |
T244 |
T245 |
is_a |
bind,promoting |
| R230 |
T247 |
T108 |
of_a |
produce,Angiotensin A |
| R232 |
T99 |
T248 |
is_a |
aspartate decarboxylase,via |
| R233 |
T248 |
165 |
of_a |
via,Angiotensin II |
| R234 |
165 |
T247 |
is_a |
Angiotensin II,produce |
| R236 |
169 |
T250 |
is_a |
ACE2,cleavage |
| R237 |
T250 |
T108 |
of_a |
cleavage,Angiotensin A |
| R238 |
T108 |
T249 |
is_a |
Angiotensin A,via |
| R239 |
T249 |
168 |
of_a |
via,Alamandine |
| R240 |
T108 |
T249 |
of_a |
Angiotensin A,via |
| R241 |
T249 |
T247 |
coreference |
via,produce |
| R242 |
170 |
T251 |
is_a |
ACE2,cleave |
| R243 |
T251 |
171 |
of_a |
cleave,Angiotensin I |
| R244 |
171 |
T252 |
is_a |
Angiotensin I,form |
| R245 |
T252 |
T112 |
of_a |
form,Angiotensin 1-9 |
| R246 |
T105 |
T253 |
of_a |
AT2R,targets |
| R247 |
T112 |
T253 |
is_a |
Angiotensin 1-9,targets |
| R248 |
T116 |
T254 |
is_a |
Angiotensin III,targeting |
| R249 |
174 |
T254 |
of_a |
AT1R,targeting |
| R250 |
T120 |
T255 |
is_a |
Angiotensin IV,targeting |
| R251 |
T124 |
T255 |
of_a |
AT4R,targeting |
| R252 |
T22 |
T199 |
of_a |
RAS,central roles |
| R253 |
177 |
T199 |
of_a |
COVID-19,central roles |
| R254 |
T256 |
T123 |
is_a |
aside,Angiotensin III |
| R255 |
T257 |
T258 |
coreference |
system,RAS |
| R256 |
T23 |
T258 |
is_a |
'counter-regulatory',RAS |
| R257 |
T257 |
T259 |
of_a |
system,homeostasis |
| R258 |
T23 |
T260 |
is_a |
'counter-regulatory',modulate |
| R259 |
T260 |
T259 |
is_a |
modulate,homeostasis |
| R26 |
T69 |
T65 |
at |
damage,lung |
| R260 |
181 |
T261 |
of_a |
MasR,targeting |
| R261 |
T235 |
T261 |
is_a |
Angiotensin 1-7,targeting |
| R262 |
T106 |
T262 |
of_a |
AT2R,targeting |
| R263 |
T114 |
T262 |
is_a |
Angiotensin 1-9,targeting |
| R264 |
180 |
T263 |
is_a |
Alamandine,targeting |
| R265 |
182 |
T263 |
of_a |
MRGD,targeting |
| R266 |
183 |
T264 |
of_a |
ACE2,targeting |
| R267 |
T109 |
T264 |
is_a |
Angiotensin A,targeting |
| R268 |
T121 |
T265 |
is_a |
Angiotensin IV,targeting |
| R269 |
T143 |
T265 |
of_a |
AT4R,targeting |
| R27 |
T69 |
T66 |
at |
damage,heart |
| R271 |
T106 |
T266 |
has_a |
AT2R,vasodilatator |
| R272 |
182 |
T266 |
has_a |
MRGD,vasodilatator |
| R273 |
183 |
T266 |
has_a |
ACE2,vasodilatator |
| R274 |
181 |
T266 |
has_a |
MasR,vasodilatator |
| R275 |
T143 |
T266 |
has_a |
AT4R,vasodilatator |
| R276 |
T267 |
T148 |
has_a |
These peptides,cardioprotective |
| R277 |
T267 |
T149 |
has_a |
These peptides,vasoactive |
| R278 |
T267 |
T150 |
has_a |
These peptides,anti-hypertensive |
| R279 |
T267 |
T151 |
has_a |
These peptides,anti-hypertrophic |
| R28 |
T69 |
T67 |
at |
damage,kidney |
| R280 |
T267 |
T153 |
has_a |
These peptides,anti-inflammatory |
| R281 |
T267 |
T235 |
coreference |
These peptides,Angiotensin 1-7 |
| R282 |
T267 |
T114 |
coreference |
These peptides,Angiotensin 1-9 |
| R283 |
T267 |
180 |
coreference |
These peptides,Alamandine |
| R284 |
T267 |
T109 |
coreference |
These peptides,Angiotensin A |
| R285 |
T267 |
T121 |
coreference |
These peptides,Angiotensin IV |
| R286 |
T268 |
T267 |
coreference |
Such naturally-produced molecules,These peptides |
| R287 |
T24 |
T268 |
of_a |
RAS,Such naturally-produced molecules |
| R288 |
T270 |
T25 |
is_a |
over-activation,RAS |
| R289 |
186 |
T270 |
by |
SARS-CoV-2,over-activation |
| R29 |
T69 |
T68 |
at |
damage,testicle |
| R290 |
T269 |
T270 |
is_a |
counteract,over-activation |
| R291 |
T271 |
187 |
is_a |
reverse,COVID-19 |
| R295 |
188 |
T189 |
of_a |
viral infection,severity |
| R296 |
190 |
191 |
has_a |
COVID-19,patients |
| R297 |
191 |
189 |
of_a |
patients,mortality |
| R298 |
T157 |
T273 |
of_a |
pro-inflammatory cytokines,release |
| R299 |
T29 |
T274 |
is_a |
RAS,control |
| R3 |
T39 |
T42 |
- |
renal,outcomes |
| R300 |
T274 |
T273 |
is_a |
control,release |
| R301 |
T268 |
T269 |
is_a |
Such naturally-produced molecules,counteract |
| R302 |
T268 |
T271 |
is_a |
Such naturally-produced molecules,reverse |
| R303 |
T28 |
T275 |
is_a |
RAS inhibitors,prevent |
| R304 |
T275 |
T156 |
cause_of |
prevent,cytokine storm |
| R305 |
T274 |
T275 |
as |
control,prevent |
| R306 |
193 |
195 |
has_a |
COVID-19,humans |
| R307 |
T276 |
T30 |
is_a |
over-reacted,RAS |
| R308 |
T158 |
T191 |
is_a |
vitamin D deficiency,dependent |
| R309 |
T191 |
196 |
on |
dependent,ACE2 |
| R310 |
197 |
T276 |
cause_of |
viral infection,over-reacted |
| R311 |
T158 |
T276 |
cause_of |
vitamin D deficiency,over-reacted |
| R312 |
193 |
T277 |
is_a |
COVID-19,depend |
| R313 |
T277 |
T276 |
on |
depend,over-reacted |
| R314 |
T280 |
T281 |
is_a |
RAS,target |
| R315 |
199 |
T278 |
of_a |
COVID-19,treatment |
| R316 |
T278 |
T281 |
is_a |
treatment,target |
| R317 |
T279 |
T281 |
using |
specific candidate chemotherapeutic drugs,target |
| R318 |
T282 |
T279 |
coreference |
proposed molecules,specific candidate chemotherapeutic drugs |
| R319 |
T159 |
T282 |
is_a |
ACE inhibitors,proposed molecules |
| R320 |
T283 |
T161 |
of_a |
AT1R,blockers |
| R322 |
T161 |
T282 |
is_a |
blockers,proposed molecules |
| R323 |
T163 |
T161 |
synonym |
antagonists,blockers |
| R324 |
204 |
T161 |
is_a |
Losartan,blockers |
| R325 |
T164 |
T161 |
is_a |
Losartan,blockers |
| R326 |
202 |
T284 |
is_a |
Angiotensin I,production |
| R327 |
T284 |
201 |
of_a |
production,Angiotensin II |
| R328 |
T285 |
T284 |
is_a |
prevent,production |
| R329 |
T166 |
T287 |
is_a |
Recombinant,ACE2 |
| R33 |
T81 |
T83 |
- |
type 1,Angiotensin II receptor |
| R330 |
206 |
T288 |
of_a |
SARS-CoV-2,spike (S) glycoprotein |
| R331 |
T291 |
T287 |
is_a |
decoy,ACE2 |
| R332 |
T290 |
T292 |
has_status |
binding,competitive |
| R333 |
T291 |
T290 |
is_a |
decoy,binding |
| R334 |
T290 |
T288 |
to |
binding,spike (S) glycoprotein |
| R335 |
T293 |
T32 |
is_a |
counter-regulatory,RAS |
| R336 |
T236 |
T173 |
is_a |
Angiotensin 1-7,natural candidate peptide drugs |
| R337 |
T115 |
T173 |
is_a |
Angiotensin 1-9,natural candidate peptide drugs |
| R338 |
209 |
T173 |
is_a |
Alamandine,natural candidate peptide drugs |
| R339 |
T110 |
T173 |
is_a |
Angiotensin A,natural candidate peptide drugs |
| R34 |
T89 |
T87 |
- |
type 2,Angiotensin II receptor |
| R340 |
T122 |
T173 |
is_a |
Angiotensin IV,natural candidate peptide drugs |
| R341 |
210 |
T294 |
of_a |
COVID-19 disorders,treat |
| R342 |
T294 |
T173 |
for |
treat,natural candidate peptide drugs |
| R343 |
211 |
T192 |
is_a |
MasR,targeted receptors |
| R344 |
T107 |
T192 |
is_a |
AT2R,targeted receptors |
| R345 |
212 |
T192 |
is_a |
MRGD,targeted receptors |
| R346 |
213 |
T192 |
is_a |
ACE2,targeted receptors |
| R347 |
T144 |
T192 |
is_a |
AT4R,targeted receptors |
| R348 |
T194 |
T193 |
of_a |
innate immune,function |
| R349 |
T195 |
T193 |
is_a |
key regulator,function |
| R350 |
T211 |
T49 |
with |
interacting,Angiotensin-Converting Enzyme 2 |
| R351 |
T5 |
T174 |
for |
'Renin-Angiotensin' System,Candidate Drugs |
| R39 |
T130 |
T129 |
- |
Angiotensin,II |
| R4 |
T40 |
T42 |
- |
cardiac,outcomes |
| R40 |
T130 |
T132 |
- |
Angiotensin,I |
| R5 |
T41 |
T42 |
- |
vascular,outcomes |
| R54 |
T164 |
T160 |
- |
Losartan,derivatives |
| R6 |
T48 |
T46 |
of_a |
pro-inflammatory,cytokine |
| R7 |
T52 |
T51 |
of_a |
blood vessels,surface |
| R76 |
197 |
T191 |
is_a |
viral infection,dependent |
| R8 |
T53 |
T51 |
of_a |
lung,surface |
| R87 |
T33 |
T195 |
is_a |
'Renin-Angiotensin' system,key regulator |
| R9 |
T54 |
T51 |
of_a |
kidney,surface |
| R95 |
T130 |
T199 |
is_a |
Angiotensin,central roles |
| R96 |
T201 |
5 |
has_a |
infected,patients |
| R97 |
T200 |
T201 |
by |
SARS-CoV-2,infected |
| R98 |
T1 |
T193 |
of_a |
renal,function |
| R99 |
T2 |
T193 |
of_a |
cardiovascular,function |
