CORD-19:d51d89ebb0dabebd141536ac836267f2df1b1bf9 JSONTXT 11 Projects

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Id Subject Object Predicate Lexical cue
TextSentencer_T1 2-10 Sentence denotes Abstract
TextSentencer_T1 2-10 Sentence denotes Abstract
TextSentencer_T1 2-10 Sentence denotes Abstract
TextSentencer_T2 11-361 Sentence denotes Life science research Genetic resources Institutional analysis Governance a b s t r a c t Public service (ex situ) micro-organism collections serve to secure genetic resources for unforeseen future needs, and importantly, to provide authenticated biomaterials for contemporaneous use in private and public entities and as upstream research materials.
TextSentencer_T2 11-361 Sentence denotes Life science research Genetic resources Institutional analysis Governance a b s t r a c t Public service (ex situ) micro-organism collections serve to secure genetic resources for unforeseen future needs, and importantly, to provide authenticated biomaterials for contemporaneous use in private and public entities and as upstream research materials.
TextSentencer_T2 11-361 Sentence denotes Life science research Genetic resources Institutional analysis Governance a b s t r a c t Public service (ex situ) micro-organism collections serve to secure genetic resources for unforeseen future needs, and importantly, to provide authenticated biomaterials for contemporaneous use in private and public entities and as upstream research materials.
TextSentencer_T3 362-483 Sentence denotes Hence, it is important to understand the functioning and strategic decisions of these providers of public good resources.
TextSentencer_T3 362-483 Sentence denotes Hence, it is important to understand the functioning and strategic decisions of these providers of public good resources.
TextSentencer_T3 362-483 Sentence denotes Hence, it is important to understand the functioning and strategic decisions of these providers of public good resources.
TextSentencer_T4 484-562 Sentence denotes 2 The existing literature tends to use case studies of individual collections.
TextSentencer_T4 484-562 Sentence denotes 2 The existing literature tends to use case studies of individual collections.
TextSentencer_T4 484-562 Sentence denotes 2 The existing literature tends to use case studies of individual collections.
TextSentencer_T5 563-863 Sentence denotes This paper uses a unique worldwide survey of microbial collections to analyse the heterogeneity among culture collections, and to empirically assess the economic and institutional conditions that contribute to this heterogeneity with respect to conservation choice and associated industry spillovers.
TextSentencer_T5 563-863 Sentence denotes This paper uses a unique worldwide survey of microbial collections to analyse the heterogeneity among culture collections, and to empirically assess the economic and institutional conditions that contribute to this heterogeneity with respect to conservation choice and associated industry spillovers.
TextSentencer_T5 563-863 Sentence denotes This paper uses a unique worldwide survey of microbial collections to analyse the heterogeneity among culture collections, and to empirically assess the economic and institutional conditions that contribute to this heterogeneity with respect to conservation choice and associated industry spillovers.
TextSentencer_T6 864-1019 Sentence denotes Results suggest that in the short run publicprivate partnerships may indeed support knowledge accumulation with particularly strong public good properties.
TextSentencer_T6 864-1019 Sentence denotes Results suggest that in the short run publicprivate partnerships may indeed support knowledge accumulation with particularly strong public good properties.
TextSentencer_T6 864-1019 Sentence denotes Results suggest that in the short run publicprivate partnerships may indeed support knowledge accumulation with particularly strong public good properties.
TextSentencer_T7 1020-1256 Sentence denotes It is important to be aware of this strong tie, in order to steer also the long term conservation patrimony into one that offers not only short term usability but also resilience to future unforeseen needs e.g. of emerging crop plagues.
TextSentencer_T7 1020-1256 Sentence denotes It is important to be aware of this strong tie, in order to steer also the long term conservation patrimony into one that offers not only short term usability but also resilience to future unforeseen needs e.g. of emerging crop plagues.
TextSentencer_T7 1020-1256 Sentence denotes It is important to be aware of this strong tie, in order to steer also the long term conservation patrimony into one that offers not only short term usability but also resilience to future unforeseen needs e.g. of emerging crop plagues.
TextSentencer_T8 1257-1277 Sentence denotes # 2013 Elsevier Ltd.
TextSentencer_T8 1257-1277 Sentence denotes # 2013 Elsevier Ltd.
TextSentencer_T8 1257-1277 Sentence denotes # 2013 Elsevier Ltd.
TextSentencer_T9 1278-1298 Sentence denotes All rights reserved.
TextSentencer_T9 1278-1298 Sentence denotes All rights reserved.
TextSentencer_T9 1278-1298 Sentence denotes All rights reserved.
TextSentencer_T10 1299-1540 Sentence denotes 2 Here we refer to public goods in a general way as goods which are relatively costly to exclude others from using, and, whose consumption by one user does not in a significant way reduce the quantity of the good available for others to use.
TextSentencer_T10 1299-1540 Sentence denotes 2 Here we refer to public goods in a general way as goods which are relatively costly to exclude others from using, and, whose consumption by one user does not in a significant way reduce the quantity of the good available for others to use.
TextSentencer_T10 1299-1540 Sentence denotes 2 Here we refer to public goods in a general way as goods which are relatively costly to exclude others from using, and, whose consumption by one user does not in a significant way reduce the quantity of the good available for others to use.
TextSentencer_T11 1542-1608 Sentence denotes The heterogeneity of public ex situ collections of microorganisms:
TextSentencer_T11 1542-1608 Sentence denotes The heterogeneity of public ex situ collections of microorganisms:
TextSentencer_T11 1542-1608 Sentence denotes The heterogeneity of public ex situ collections of microorganisms:
TextSentencer_T12 1609-1694 Sentence denotes Empirical evidence about conservation practices, industry spillovers and public goods
TextSentencer_T12 1609-1694 Sentence denotes Empirical evidence about conservation practices, industry spillovers and public goods
TextSentencer_T12 1609-1694 Sentence denotes Empirical evidence about conservation practices, industry spillovers and public goods
TextSentencer_T13 1695-1844 Sentence denotes In recent years, the life sciences research community has been involved in a vigorous debate over what should and should not be in the public domain.
TextSentencer_T13 1695-1844 Sentence denotes In recent years, the life sciences research community has been involved in a vigorous debate over what should and should not be in the public domain.
TextSentencer_T13 1695-1844 Sentence denotes In recent years, the life sciences research community has been involved in a vigorous debate over what should and should not be in the public domain.
TextSentencer_T14 1845-2001 Sentence denotes Many of the discussions have been over preserving public access to basic research assets, such as basic biological research materials and genomic databases.
TextSentencer_T14 1845-2001 Sentence denotes Many of the discussions have been over preserving public access to basic research assets, such as basic biological research materials and genomic databases.
TextSentencer_T14 1845-2001 Sentence denotes Many of the discussions have been over preserving public access to basic research assets, such as basic biological research materials and genomic databases.
TextSentencer_T15 2002-2178 Sentence denotes The debate has been accentuated by the profound changes in e n v i r o n m e n t a l s c i e n c e & p o l i c y 3 3 ( 2 0 1 3 ) 1 9 -2 7 a r t i c l e i n f o Article history:
TextSentencer_T15 2002-2178 Sentence denotes The debate has been accentuated by the profound changes in e n v i r o n m e n t a l s c i e n c e & p o l i c y 3 3 ( 2 0 1 3 ) 1 9 -2 7 a r t i c l e i n f o Article history:
TextSentencer_T15 2002-2178 Sentence denotes The debate has been accentuated by the profound changes in e n v i r o n m e n t a l s c i e n c e & p o l i c y 3 3 ( 2 0 1 3 ) 1 9 -2 7 a r t i c l e i n f o Article history:
TextSentencer_T16 2179-2474 Sentence denotes the organisational structure and the funding of life science research infrastructures, especially since the early 1990s, when the commercial promise of genomics became apparent, and private funding for genomics in for-profit companies began to accelerate (Cook-Deegan and Dedeurwaerdere, 2006) .
TextSentencer_T16 2179-2474 Sentence denotes the organisational structure and the funding of life science research infrastructures, especially since the early 1990s, when the commercial promise of genomics became apparent, and private funding for genomics in for-profit companies began to accelerate (Cook-Deegan and Dedeurwaerdere, 2006) .
TextSentencer_T16 2179-2474 Sentence denotes the organisational structure and the funding of life science research infrastructures, especially since the early 1990s, when the commercial promise of genomics became apparent, and private funding for genomics in for-profit companies began to accelerate (Cook-Deegan and Dedeurwaerdere, 2006) .
TextSentencer_T17 2475-2729 Sentence denotes Much scholarly research on these new organisational and institutional mechanisms for providing public access to basic knowledge resources in the life sciences has focused on human genetics and plant breeding (Harvey and McMeekin, 2007; Overwalle, 2009 ).
TextSentencer_T17 2475-2729 Sentence denotes Much scholarly research on these new organisational and institutional mechanisms for providing public access to basic knowledge resources in the life sciences has focused on human genetics and plant breeding (Harvey and McMeekin, 2007; Overwalle, 2009 ).
TextSentencer_T17 2475-2729 Sentence denotes Much scholarly research on these new organisational and institutional mechanisms for providing public access to basic knowledge resources in the life sciences has focused on human genetics and plant breeding (Harvey and McMeekin, 2007; Overwalle, 2009 ).
TextSentencer_T18 2730-2870 Sentence denotes This paper aims to contribute to the understanding of these changes by focusing on a case study within the particular field of microbiology.
TextSentencer_T18 2730-2870 Sentence denotes This paper aims to contribute to the understanding of these changes by focusing on a case study within the particular field of microbiology.
TextSentencer_T18 2730-2870 Sentence denotes This paper aims to contribute to the understanding of these changes by focusing on a case study within the particular field of microbiology.
TextSentencer_T19 2871-2908 Sentence denotes The reason for this choice is double.
TextSentencer_T19 2871-2908 Sentence denotes The reason for this choice is double.
TextSentencer_T19 2871-2908 Sentence denotes The reason for this choice is double.
TextSentencer_T20 2909-3226 Sentence denotes First, the international network of public culture collections historically has been one of the first global research infrastructures providing public access to basic biological research materials (Stern, 2004; Reichman et al., 2013) , held in a distributed network of collections throughout the world (Smith, 2003) .
TextSentencer_T20 2909-3226 Sentence denotes First, the international network of public culture collections historically has been one of the first global research infrastructures providing public access to basic biological research materials (Stern, 2004; Reichman et al., 2013) , held in a distributed network of collections throughout the world (Smith, 2003) .
TextSentencer_T20 2909-3226 Sentence denotes First, the international network of public culture collections historically has been one of the first global research infrastructures providing public access to basic biological research materials (Stern, 2004; Reichman et al., 2013) , held in a distributed network of collections throughout the world (Smith, 2003) .
TextSentencer_T21 3227-3511 Sentence denotes Second, the importance of these public collections has grown over the last two decades, with their transformation to multi-service biological resources centres, which provide expertise in genetics and bioinformatics, in addition to their traditional taxonomic expertise (OECD, 2001) .
TextSentencer_T21 3227-3511 Sentence denotes Second, the importance of these public collections has grown over the last two decades, with their transformation to multi-service biological resources centres, which provide expertise in genetics and bioinformatics, in addition to their traditional taxonomic expertise (OECD, 2001) .
TextSentencer_T21 3227-3511 Sentence denotes Second, the importance of these public collections has grown over the last two decades, with their transformation to multi-service biological resources centres, which provide expertise in genetics and bioinformatics, in addition to their traditional taxonomic expertise (OECD, 2001) .
TextSentencer_T22 3512-3727 Sentence denotes As a result, the network of public microbial collections has increasingly evolved from purely governmental institutions to a heterogeneous group encompassing both public sector and private sector funding strategies.
TextSentencer_T22 3512-3727 Sentence denotes As a result, the network of public microbial collections has increasingly evolved from purely governmental institutions to a heterogeneous group encompassing both public sector and private sector funding strategies.
TextSentencer_T22 3512-3727 Sentence denotes As a result, the network of public microbial collections has increasingly evolved from purely governmental institutions to a heterogeneous group encompassing both public sector and private sector funding strategies.
TextSentencer_T23 3728-4035 Sentence denotes Therefore, culture collections is an interesting case of a research infrastructure providing publicly available knowledge assets, whose organisational structure is increasingly based on public-private economic interdependencies (please refer to the electronic supplement for additional background to PSMCs).
TextSentencer_T23 3728-4035 Sentence denotes Therefore, culture collections is an interesting case of a research infrastructure providing publicly available knowledge assets, whose organisational structure is increasingly based on public-private economic interdependencies (please refer to the electronic supplement for additional background to PSMCs).
TextSentencer_T23 3728-4035 Sentence denotes Therefore, culture collections is an interesting case of a research infrastructure providing publicly available knowledge assets, whose organisational structure is increasingly based on public-private economic interdependencies (please refer to the electronic supplement for additional background to PSMCs).
TextSentencer_T24 4036-4400 Sentence denotes The role and functions of the microbial collections as a basic life science research infrastructure bears a lot of similarities with other ex situ collections, especially in the field of animal and plant genetic resources, which have been studied elsewhere (Fowler et al., 2001; Gollin et al., 2000; Roa-Rodríguez and van Dooren, 2008; Mä ki-Tanila et al., 2008) .
TextSentencer_T24 4036-4400 Sentence denotes The role and functions of the microbial collections as a basic life science research infrastructure bears a lot of similarities with other ex situ collections, especially in the field of animal and plant genetic resources, which have been studied elsewhere (Fowler et al., 2001; Gollin et al., 2000; Roa-Rodríguez and van Dooren, 2008; Mä ki-Tanila et al., 2008) .
TextSentencer_T24 4036-4400 Sentence denotes The role and functions of the microbial collections as a basic life science research infrastructure bears a lot of similarities with other ex situ collections, especially in the field of animal and plant genetic resources, which have been studied elsewhere (Fowler et al., 2001; Gollin et al., 2000; Roa-Rodríguez and van Dooren, 2008; Mä ki-Tanila et al., 2008) .
TextSentencer_T25 4401-4475 Sentence denotes However, two important features are specific to the microbial collections.
TextSentencer_T25 4401-4475 Sentence denotes However, two important features are specific to the microbial collections.
TextSentencer_T25 4401-4475 Sentence denotes However, two important features are specific to the microbial collections.
TextSentencer_T26 4476-4606 Sentence denotes First, microbial organisms have an extremely high genetic variation within species and very high mutation rates upon reproduction.
TextSentencer_T26 4476-4606 Sentence denotes First, microbial organisms have an extremely high genetic variation within species and very high mutation rates upon reproduction.
TextSentencer_T26 4476-4606 Sentence denotes First, microbial organisms have an extremely high genetic variation within species and very high mutation rates upon reproduction.
TextSentencer_T27 4607-4713 Sentence denotes As a result, there is no equivalent to the relatively well-defined species concept for plants and animals.
TextSentencer_T27 4607-4713 Sentence denotes As a result, there is no equivalent to the relatively well-defined species concept for plants and animals.
TextSentencer_T27 4607-4713 Sentence denotes As a result, there is no equivalent to the relatively well-defined species concept for plants and animals.
TextSentencer_T28 4714-4818 Sentence denotes Therefore microbial science depends on the in vitro organisms held in the microbial ex situ collections.
TextSentencer_T28 4714-4818 Sentence denotes Therefore microbial science depends on the in vitro organisms held in the microbial ex situ collections.
TextSentencer_T28 4714-4818 Sentence denotes Therefore microbial science depends on the in vitro organisms held in the microbial ex situ collections.
TextSentencer_T29 4819-5315 Sentence denotes This explains the importance of a broad range of wild biodiversity held and still massively collected by the microbial collections, while the ex situ conservation efforts in the agricultural plant and animal collections that have been the focus of previous studies the main focus is on domesticated varieties and breeds (Halewood, 2010) Second, the public microbial collections provide on average a comparable amount of materials to public sector and private sector entities in the life sciences.
TextSentencer_T29 4819-5315 Sentence denotes This explains the importance of a broad range of wild biodiversity held and still massively collected by the microbial collections, while the ex situ conservation efforts in the agricultural plant and animal collections that have been the focus of previous studies the main focus is on domesticated varieties and breeds (Halewood, 2010) Second, the public microbial collections provide on average a comparable amount of materials to public sector and private sector entities in the life sciences.
TextSentencer_T29 4819-5315 Sentence denotes This explains the importance of a broad range of wild biodiversity held and still massively collected by the microbial collections, while the ex situ conservation efforts in the agricultural plant and animal collections that have been the focus of previous studies the main focus is on domesticated varieties and breeds (Halewood, 2010) Second, the public microbial collections provide on average a comparable amount of materials to public sector and private sector entities in the life sciences.
TextSentencer_T30 5316-5545 Sentence denotes This hybrid character of the distribution practices of the public microbial collections makes this case a rich source for quantitative analysis of conservation and distribution strategies in life science research infrastructures.
TextSentencer_T30 5316-5545 Sentence denotes This hybrid character of the distribution practices of the public microbial collections makes this case a rich source for quantitative analysis of conservation and distribution strategies in life science research infrastructures.
TextSentencer_T30 5316-5545 Sentence denotes This hybrid character of the distribution practices of the public microbial collections makes this case a rich source for quantitative analysis of conservation and distribution strategies in life science research infrastructures.
TextSentencer_T31 5546-5762 Sentence denotes The main objective of this paper is to enhance our understanding about the organisational heterogeneity amongst public service culture collections, which increasingly include hybrid public-private funding strategies.
TextSentencer_T31 5546-5762 Sentence denotes The main objective of this paper is to enhance our understanding about the organisational heterogeneity amongst public service culture collections, which increasingly include hybrid public-private funding strategies.
TextSentencer_T31 5546-5762 Sentence denotes The main objective of this paper is to enhance our understanding about the organisational heterogeneity amongst public service culture collections, which increasingly include hybrid public-private funding strategies.
TextSentencer_T32 5763-6014 Sentence denotes In particular the paper aims to analyse core aspects of the economic and institutional conditions that contribute to PSMCs' conservation of microbial material and its distribution as publicly available basic knowledge assets for life science research.
TextSentencer_T32 5763-6014 Sentence denotes In particular the paper aims to analyse core aspects of the economic and institutional conditions that contribute to PSMCs' conservation of microbial material and its distribution as publicly available basic knowledge assets for life science research.
TextSentencer_T32 5763-6014 Sentence denotes In particular the paper aims to analyse core aspects of the economic and institutional conditions that contribute to PSMCs' conservation of microbial material and its distribution as publicly available basic knowledge assets for life science research.
TextSentencer_T33 6015-6192 Sentence denotes It is expected that this analysis will contribute to the design of strategies that secure the sustained long term conservation of microbial material with public good properties.
TextSentencer_T33 6015-6192 Sentence denotes It is expected that this analysis will contribute to the design of strategies that secure the sustained long term conservation of microbial material with public good properties.
TextSentencer_T33 6015-6192 Sentence denotes It is expected that this analysis will contribute to the design of strategies that secure the sustained long term conservation of microbial material with public good properties.
TextSentencer_T34 6193-6512 Sentence denotes This seems especially relevant in the context of uncertainty created by recent changes in the institutional landscape in which PSMCs operate, for instance due to the stress on public funding for basic research and infrastructures, and the increasing commercial interest by the industry in microbial resources generally.
TextSentencer_T34 6193-6512 Sentence denotes This seems especially relevant in the context of uncertainty created by recent changes in the institutional landscape in which PSMCs operate, for instance due to the stress on public funding for basic research and infrastructures, and the increasing commercial interest by the industry in microbial resources generally.
TextSentencer_T34 6193-6512 Sentence denotes This seems especially relevant in the context of uncertainty created by recent changes in the institutional landscape in which PSMCs operate, for instance due to the stress on public funding for basic research and infrastructures, and the increasing commercial interest by the industry in microbial resources generally.
TextSentencer_T35 6513-6702 Sentence denotes To this end primary data about the PSMCs' conservation and distribution was gathered through a worldwide survey and a sample of 103 PSMCs is subjected in this paper to statistical analysis.
TextSentencer_T35 6513-6702 Sentence denotes To this end primary data about the PSMCs' conservation and distribution was gathered through a worldwide survey and a sample of 103 PSMCs is subjected in this paper to statistical analysis.
TextSentencer_T35 6513-6702 Sentence denotes To this end primary data about the PSMCs' conservation and distribution was gathered through a worldwide survey and a sample of 103 PSMCs is subjected in this paper to statistical analysis.
TextSentencer_T36 6703-7000 Sentence denotes We find that (1) the private industry relies on PSMCs; (2) hybrid arrangements based on complementary public and commercial funding is associated with stronger specialisation in microorganisms with particularly strong public good properties and (3) the existence of public-private interdependency.
TextSentencer_T36 6703-7000 Sentence denotes We find that (1) the private industry relies on PSMCs; (2) hybrid arrangements based on complementary public and commercial funding is associated with stronger specialisation in microorganisms with particularly strong public good properties and (3) the existence of public-private interdependency.
TextSentencer_T36 6703-7000 Sentence denotes We find that (1) the private industry relies on PSMCs; (2) hybrid arrangements based on complementary public and commercial funding is associated with stronger specialisation in microorganisms with particularly strong public good properties and (3) the existence of public-private interdependency.
TextSentencer_T37 7001-7192 Sentence denotes These results call into question the role of markets alone or pure public funding alone for assuring the provision of publicly available biological resources in a globalised research context.
TextSentencer_T37 7001-7192 Sentence denotes These results call into question the role of markets alone or pure public funding alone for assuring the provision of publicly available biological resources in a globalised research context.
TextSentencer_T37 7001-7192 Sentence denotes These results call into question the role of markets alone or pure public funding alone for assuring the provision of publicly available biological resources in a globalised research context.
TextSentencer_T38 7193-7285 Sentence denotes The next section addresses the key factors behind the organisational heterogeneity of PSMCs.
TextSentencer_T38 7193-7285 Sentence denotes The next section addresses the key factors behind the organisational heterogeneity of PSMCs.
TextSentencer_T38 7193-7285 Sentence denotes The next section addresses the key factors behind the organisational heterogeneity of PSMCs.
TextSentencer_T39 7286-7496 Sentence denotes Then the analytic framework discusses the factors that are expected to play a role in the public and private investment in the PSMCs' conservation strategies regarding publicly available microbial type strains.
TextSentencer_T39 7286-7496 Sentence denotes Then the analytic framework discusses the factors that are expected to play a role in the public and private investment in the PSMCs' conservation strategies regarding publicly available microbial type strains.
TextSentencer_T39 7286-7496 Sentence denotes Then the analytic framework discusses the factors that are expected to play a role in the public and private investment in the PSMCs' conservation strategies regarding publicly available microbial type strains.
TextSentencer_T40 7497-7600 Sentence denotes We also introduce the related question about spillovers from PSMCs to the private industry (Section 3).
TextSentencer_T40 7497-7600 Sentence denotes We also introduce the related question about spillovers from PSMCs to the private industry (Section 3).
TextSentencer_T40 7497-7600 Sentence denotes We also introduce the related question about spillovers from PSMCs to the private industry (Section 3).
TextSentencer_T41 7601-7743 Sentence denotes Section 4 presents the materials and methodology of the statistical analysis; Section 5 presents the results and discusses their implications.
TextSentencer_T41 7601-7743 Sentence denotes Section 4 presents the materials and methodology of the statistical analysis; Section 5 presents the results and discusses their implications.
TextSentencer_T41 7601-7743 Sentence denotes Section 4 presents the materials and methodology of the statistical analysis; Section 5 presents the results and discusses their implications.
TextSentencer_T42 7744-7771 Sentence denotes The last section concludes.
TextSentencer_T42 7744-7771 Sentence denotes The last section concludes.
TextSentencer_T42 7744-7771 Sentence denotes The last section concludes.
TextSentencer_T43 7772-7834 Sentence denotes The heterogeneity of public service microbial collections 2.1.
TextSentencer_T43 7772-7834 Sentence denotes The heterogeneity of public service microbial collections 2.1.
TextSentencer_T43 7772-7834 Sentence denotes The heterogeneity of public service microbial collections 2.1.
TextSentencer_T44 7835-8024 Sentence denotes PSMCs as an infrastructure for public research materials in the genomic area PSMCs link academia, industry, government and international knowledge providers and users of microbial material.
TextSentencer_T44 7835-8024 Sentence denotes PSMCs as an infrastructure for public research materials in the genomic area PSMCs link academia, industry, government and international knowledge providers and users of microbial material.
TextSentencer_T44 7835-8024 Sentence denotes PSMCs as an infrastructure for public research materials in the genomic area PSMCs link academia, industry, government and international knowledge providers and users of microbial material.
TextSentencer_T45 8025-8221 Sentence denotes As such they are knowledge hubs, sensu Stern (2004) , for the life sciences that support innovation by facilitating acquisition of and access to existing research materials (Furman et al., 2010) .
TextSentencer_T45 8025-8221 Sentence denotes As such they are knowledge hubs, sensu Stern (2004) , for the life sciences that support innovation by facilitating acquisition of and access to existing research materials (Furman et al., 2010) .
TextSentencer_T45 8025-8221 Sentence denotes As such they are knowledge hubs, sensu Stern (2004) , for the life sciences that support innovation by facilitating acquisition of and access to existing research materials (Furman et al., 2010) .
TextSentencer_T46 8222-8306 Sentence denotes This is done through a worldwide network of centralised deposit and access services.
TextSentencer_T46 8222-8306 Sentence denotes This is done through a worldwide network of centralised deposit and access services.
TextSentencer_T46 8222-8306 Sentence denotes This is done through a worldwide network of centralised deposit and access services.
TextSentencer_T47 8307-8400 Sentence denotes As knowledge aggregators, they can be considered as the research libraries for bio-materials.
TextSentencer_T47 8307-8400 Sentence denotes As knowledge aggregators, they can be considered as the research libraries for bio-materials.
TextSentencer_T47 8307-8400 Sentence denotes As knowledge aggregators, they can be considered as the research libraries for bio-materials.
TextSentencer_T48 8401-8475 Sentence denotes See electronic supplement for further background and description of PSMCs.
TextSentencer_T48 8401-8475 Sentence denotes See electronic supplement for further background and description of PSMCs.
TextSentencer_T48 8401-8475 Sentence denotes See electronic supplement for further background and description of PSMCs.
TextSentencer_T49 8476-8651 Sentence denotes One particular element in this research infrastructure is the microbial category known as type strains, which are the basic reference materials for identifying microbial taxa.
TextSentencer_T49 8476-8651 Sentence denotes One particular element in this research infrastructure is the microbial category known as type strains, which are the basic reference materials for identifying microbial taxa.
TextSentencer_T49 8476-8651 Sentence denotes One particular element in this research infrastructure is the microbial category known as type strains, which are the basic reference materials for identifying microbial taxa.
TextSentencer_T50 8652-8839 Sentence denotes As such type strains are a fundamental part of the general research infrastructure in microbiology that serves applied and basic research, both for public sector and private sector users.
TextSentencer_T50 8652-8839 Sentence denotes As such type strains are a fundamental part of the general research infrastructure in microbiology that serves applied and basic research, both for public sector and private sector users.
TextSentencer_T50 8652-8839 Sentence denotes As such type strains are a fundamental part of the general research infrastructure in microbiology that serves applied and basic research, both for public sector and private sector users.
TextSentencer_T51 8840-9025 Sentence denotes Technological advances have increased the value of microbes and their parts, by creating new commercial applications, and by lowering the uncertainty of the product development process.
TextSentencer_T51 8840-9025 Sentence denotes Technological advances have increased the value of microbes and their parts, by creating new commercial applications, and by lowering the uncertainty of the product development process.
TextSentencer_T51 8840-9025 Sentence denotes Technological advances have increased the value of microbes and their parts, by creating new commercial applications, and by lowering the uncertainty of the product development process.
TextSentencer_T52 9026-9235 Sentence denotes For instance, market oriented policy planners in the USA and elsewhere have realised the opportunity to diminish time laps between basic research findings and commercialised products (Rai, 1999; Bartsev, Pers.
TextSentencer_T52 9026-9235 Sentence denotes For instance, market oriented policy planners in the USA and elsewhere have realised the opportunity to diminish time laps between basic research findings and commercialised products (Rai, 1999; Bartsev, Pers.
TextSentencer_T52 9026-9235 Sentence denotes For instance, market oriented policy planners in the USA and elsewhere have realised the opportunity to diminish time laps between basic research findings and commercialised products (Rai, 1999; Bartsev, Pers.
TextSentencer_T53 9236-9244 Sentence denotes Comm.) .
TextSentencer_T53 9236-9244 Sentence denotes Comm.) .
TextSentencer_T53 9236-9244 Sentence denotes Comm.) .
TextSentencer_T54 9245-9590 Sentence denotes This has come timely because financial pressure among PSMC have mounted under rapidly accumulating stocks of microbes, while governments' finances are undergoing increasing stress (Baker, 2004) : a major challenge is associated with the high costs that are incurred in the conservation, quality management and documentation of microbial strains.
TextSentencer_T54 9245-9590 Sentence denotes This has come timely because financial pressure among PSMC have mounted under rapidly accumulating stocks of microbes, while governments' finances are undergoing increasing stress (Baker, 2004) : a major challenge is associated with the high costs that are incurred in the conservation, quality management and documentation of microbial strains.
TextSentencer_T54 9245-9590 Sentence denotes This has come timely because financial pressure among PSMC have mounted under rapidly accumulating stocks of microbes, while governments' finances are undergoing increasing stress (Baker, 2004) : a major challenge is associated with the high costs that are incurred in the conservation, quality management and documentation of microbial strains.
TextSentencer_T55 9591-9782 Sentence denotes For instance it is estimated that one million USD are needed for creating a new collection of about five thousand strains, excluding the costs of long term maintenance and use (Baker, 2004) .
TextSentencer_T55 9591-9782 Sentence denotes For instance it is estimated that one million USD are needed for creating a new collection of about five thousand strains, excluding the costs of long term maintenance and use (Baker, 2004) .
TextSentencer_T55 9591-9782 Sentence denotes For instance it is estimated that one million USD are needed for creating a new collection of about five thousand strains, excluding the costs of long term maintenance and use (Baker, 2004) .
TextSentencer_T56 9783-10106 Sentence denotes In this context, the income generated by the selling of microbial strains is an important source of income that complements other non-governmental sources of income, including contract research, identification services, and, where this applies, income from patent and safety deposits as found in this paper (see Section 3).
TextSentencer_T56 9783-10106 Sentence denotes In this context, the income generated by the selling of microbial strains is an important source of income that complements other non-governmental sources of income, including contract research, identification services, and, where this applies, income from patent and safety deposits as found in this paper (see Section 3).
TextSentencer_T56 9783-10106 Sentence denotes In this context, the income generated by the selling of microbial strains is an important source of income that complements other non-governmental sources of income, including contract research, identification services, and, where this applies, income from patent and safety deposits as found in this paper (see Section 3).
TextSentencer_T57 10107-10220 Sentence denotes Hence, new conditions have been created for private cost sharing of public collections (Furman and Stern, 2006) .
TextSentencer_T57 10107-10220 Sentence denotes Hence, new conditions have been created for private cost sharing of public collections (Furman and Stern, 2006) .
TextSentencer_T57 10107-10220 Sentence denotes Hence, new conditions have been created for private cost sharing of public collections (Furman and Stern, 2006) .
TextSentencer_T58 10221-10453 Sentence denotes In an associated manner, in order to promote the development of commercial services, culture collections have introduced formal Material Transfer Agreements (MTAs) to govern their exchange practices and apply for ISO certifications.
TextSentencer_T58 10221-10453 Sentence denotes In an associated manner, in order to promote the development of commercial services, culture collections have introduced formal Material Transfer Agreements (MTAs) to govern their exchange practices and apply for ISO certifications.
TextSentencer_T58 10221-10453 Sentence denotes In an associated manner, in order to promote the development of commercial services, culture collections have introduced formal Material Transfer Agreements (MTAs) to govern their exchange practices and apply for ISO certifications.
TextSentencer_T59 10454-10626 Sentence denotes More recently, the most advanced collections are aiming to develop a whole new set of services around microbial, genomic and proteomic databases and related bioinformatics.
TextSentencer_T59 10454-10626 Sentence denotes More recently, the most advanced collections are aiming to develop a whole new set of services around microbial, genomic and proteomic databases and related bioinformatics.
TextSentencer_T59 10454-10626 Sentence denotes More recently, the most advanced collections are aiming to develop a whole new set of services around microbial, genomic and proteomic databases and related bioinformatics.
TextSentencer_T60 10627-10891 Sentence denotes This, in the long term, may cause further commercial restrictions on access and use of microbial research materials from the PSMCs that might oppose their avowed goals of providing widely available technological and scientific information (Reichman et al., 2009 ).
TextSentencer_T60 10627-10891 Sentence denotes This, in the long term, may cause further commercial restrictions on access and use of microbial research materials from the PSMCs that might oppose their avowed goals of providing widely available technological and scientific information (Reichman et al., 2009 ).
TextSentencer_T60 10627-10891 Sentence denotes This, in the long term, may cause further commercial restrictions on access and use of microbial research materials from the PSMCs that might oppose their avowed goals of providing widely available technological and scientific information (Reichman et al., 2009 ).
TextSentencer_T61 10892-11034 Sentence denotes PSMCs have adopted different strategies to cope both with the new commercial opportunities and the need for developing new areas of expertise.
TextSentencer_T61 10892-11034 Sentence denotes PSMCs have adopted different strategies to cope both with the new commercial opportunities and the need for developing new areas of expertise.
TextSentencer_T61 10892-11034 Sentence denotes PSMCs have adopted different strategies to cope both with the new commercial opportunities and the need for developing new areas of expertise.
TextSentencer_T62 11035-11205 Sentence denotes The difference in such strategies largely owe to collections's scale, type of operations, and the underlying incentives that guide their operations and strategic choices.
TextSentencer_T62 11035-11205 Sentence denotes The difference in such strategies largely owe to collections's scale, type of operations, and the underlying incentives that guide their operations and strategic choices.
TextSentencer_T62 11035-11205 Sentence denotes The difference in such strategies largely owe to collections's scale, type of operations, and the underlying incentives that guide their operations and strategic choices.
TextSentencer_T63 11206-11403 Sentence denotes In this context, it is useful to differentiate the collections regarding their different functions for society, such as support for basic research or infrastructure, and their industry orientation.
TextSentencer_T63 11206-11403 Sentence denotes In this context, it is useful to differentiate the collections regarding their different functions for society, such as support for basic research or infrastructure, and their industry orientation.
TextSentencer_T63 11206-11403 Sentence denotes In this context, it is useful to differentiate the collections regarding their different functions for society, such as support for basic research or infrastructure, and their industry orientation.
TextSentencer_T64 11404-11685 Sentence denotes Table 1 provides examples illustrating the heterogeneity among well-known collections in this regard, further explained in the Almus and Nerlinger, 1999; Arora et al., 2005; Daniel and Prasad, 2010; Greene, 2003; Parry, 2004; Rai et al., 2008; Sigler, 2004 ; electronic supplement.
TextSentencer_T64 11404-11685 Sentence denotes Table 1 provides examples illustrating the heterogeneity among well-known collections in this regard, further explained in the Almus and Nerlinger, 1999; Arora et al., 2005; Daniel and Prasad, 2010; Greene, 2003; Parry, 2004; Rai et al., 2008; Sigler, 2004 ; electronic supplement.
TextSentencer_T64 11404-11685 Sentence denotes Table 1 provides examples illustrating the heterogeneity among well-known collections in this regard, further explained in the Almus and Nerlinger, 1999; Arora et al., 2005; Daniel and Prasad, 2010; Greene, 2003; Parry, 2004; Rai et al., 2008; Sigler, 2004 ; electronic supplement.
TextSentencer_T65 11686-11800 Sentence denotes The heterogeneity of PSMCs has implications for the level of public funding support required for their operations.
TextSentencer_T65 11686-11800 Sentence denotes The heterogeneity of PSMCs has implications for the level of public funding support required for their operations.
TextSentencer_T65 11686-11800 Sentence denotes The heterogeneity of PSMCs has implications for the level of public funding support required for their operations.
TextSentencer_T66 11801-11922 Sentence denotes Collections essentially oriented towards serving traditional public sector users are largely dependent on public funding.
TextSentencer_T66 11801-11922 Sentence denotes Collections essentially oriented towards serving traditional public sector users are largely dependent on public funding.
TextSentencer_T66 11801-11922 Sentence denotes Collections essentially oriented towards serving traditional public sector users are largely dependent on public funding.
TextSentencer_T67 11923-12136 Sentence denotes In contrast, collections holding resources that are of direct interest to specialised activities in the private sector, have more opportunities for developing supplementary commercial income generating activities.
TextSentencer_T67 11923-12136 Sentence denotes In contrast, collections holding resources that are of direct interest to specialised activities in the private sector, have more opportunities for developing supplementary commercial income generating activities.
TextSentencer_T67 11923-12136 Sentence denotes In contrast, collections holding resources that are of direct interest to specialised activities in the private sector, have more opportunities for developing supplementary commercial income generating activities.
TextSentencer_T68 12137-12312 Sentence denotes Nevertheless virtually all collections require a certain level of public support for maintaining public access to their infrastructure and research related microbial holdings.
TextSentencer_T68 12137-12312 Sentence denotes Nevertheless virtually all collections require a certain level of public support for maintaining public access to their infrastructure and research related microbial holdings.
TextSentencer_T68 12137-12312 Sentence denotes Nevertheless virtually all collections require a certain level of public support for maintaining public access to their infrastructure and research related microbial holdings.
TextSentencer_T69 12313-12651 Sentence denotes Because of the use of the basic research materials held in the PSMCs both by public and private sector entities, PSMCs aptly illustrate the governance challenges of life science research which is increasingly situated in the so-called Pasteur's quadrant, where research is both basic in nature and userinspired and driven (Stokes, 1997) .
TextSentencer_T69 12313-12651 Sentence denotes Because of the use of the basic research materials held in the PSMCs both by public and private sector entities, PSMCs aptly illustrate the governance challenges of life science research which is increasingly situated in the so-called Pasteur's quadrant, where research is both basic in nature and userinspired and driven (Stokes, 1997) .
TextSentencer_T69 12313-12651 Sentence denotes Because of the use of the basic research materials held in the PSMCs both by public and private sector entities, PSMCs aptly illustrate the governance challenges of life science research which is increasingly situated in the so-called Pasteur's quadrant, where research is both basic in nature and userinspired and driven (Stokes, 1997) .
TextSentencer_T70 12652-12954 Sentence denotes In order to understand the PSMCs' conservation strategies they have to be analysed within their microeconomic institutional and organisational context, not least regarding the necessary role of public research for innovation (Rosenberg and Nelson, 1994; Mowery and Rosenberg, 1998; King et al., 2005) .
TextSentencer_T70 12652-12954 Sentence denotes In order to understand the PSMCs' conservation strategies they have to be analysed within their microeconomic institutional and organisational context, not least regarding the necessary role of public research for innovation (Rosenberg and Nelson, 1994; Mowery and Rosenberg, 1998; King et al., 2005) .
TextSentencer_T70 12652-12954 Sentence denotes In order to understand the PSMCs' conservation strategies they have to be analysed within their microeconomic institutional and organisational context, not least regarding the necessary role of public research for innovation (Rosenberg and Nelson, 1994; Mowery and Rosenberg, 1998; King et al., 2005) .
TextSentencer_T71 12955-13313 Sentence denotes Based on the literature on public goods we emphasise two key factors that respectively link to PSMCs' investment in conservation and diffusion of basic biological research materials and which will be assessed statistically in Section 4: (1) the ratio of type strain holdings in the PSMCs and (2) the share of distribution of microbes to the private industry.
TextSentencer_T71 12955-13313 Sentence denotes Based on the literature on public goods we emphasise two key factors that respectively link to PSMCs' investment in conservation and diffusion of basic biological research materials and which will be assessed statistically in Section 4: (1) the ratio of type strain holdings in the PSMCs and (2) the share of distribution of microbes to the private industry.
TextSentencer_T71 12955-13313 Sentence denotes Based on the literature on public goods we emphasise two key factors that respectively link to PSMCs' investment in conservation and diffusion of basic biological research materials and which will be assessed statistically in Section 4: (1) the ratio of type strain holdings in the PSMCs and (2) the share of distribution of microbes to the private industry.
TextSentencer_T72 13314-13576 Sentence denotes It should be noted that the conservation practices and private sector uses of PSMC holdings are affected by other factors as well, in addition to the organisational and contract related factors discussed in this paper, including the intellectual property regime.
TextSentencer_T72 13314-13576 Sentence denotes It should be noted that the conservation practices and private sector uses of PSMC holdings are affected by other factors as well, in addition to the organisational and contract related factors discussed in this paper, including the intellectual property regime.
TextSentencer_T72 13314-13576 Sentence denotes It should be noted that the conservation practices and private sector uses of PSMC holdings are affected by other factors as well, in addition to the organisational and contract related factors discussed in this paper, including the intellectual property regime.
TextSentencer_T73 13577-13785 Sentence denotes Demand for microbes is influenced by aspects such as the presence of biotechnology firms in the country where the PSMC is located, and by the supply channels available to the PSMC to source its microbes from.
TextSentencer_T73 13577-13785 Sentence denotes Demand for microbes is influenced by aspects such as the presence of biotechnology firms in the country where the PSMC is located, and by the supply channels available to the PSMC to source its microbes from.
TextSentencer_T73 13577-13785 Sentence denotes Demand for microbes is influenced by aspects such as the presence of biotechnology firms in the country where the PSMC is located, and by the supply channels available to the PSMC to source its microbes from.
TextSentencer_T74 13786-14087 Sentence denotes 3 As shown by a survey of the patterns of deposits into culture collections , restrictions related to deposits of micro-organisms are not frequent, even if this situation might change in the future as a consequence of the recently adopted Nagoya protocol on Access and Benefit Sharing in October 2010.
TextSentencer_T74 13786-14087 Sentence denotes 3 As shown by a survey of the patterns of deposits into culture collections , restrictions related to deposits of micro-organisms are not frequent, even if this situation might change in the future as a consequence of the recently adopted Nagoya protocol on Access and Benefit Sharing in October 2010.
TextSentencer_T74 13786-14087 Sentence denotes 3 As shown by a survey of the patterns of deposits into culture collections , restrictions related to deposits of micro-organisms are not frequent, even if this situation might change in the future as a consequence of the recently adopted Nagoya protocol on Access and Benefit Sharing in October 2010.
TextSentencer_T75 14088-14320 Sentence denotes In what follows, we pay attention to type strains (TS henceforth), which, as discussed above, is a category of microorganisms that have both strong public good characteristics and that are used in public and private sector research.
TextSentencer_T75 14088-14320 Sentence denotes In what follows, we pay attention to type strains (TS henceforth), which, as discussed above, is a category of microorganisms that have both strong public good characteristics and that are used in public and private sector research.
TextSentencer_T75 14088-14320 Sentence denotes In what follows, we pay attention to type strains (TS henceforth), which, as discussed above, is a category of microorganisms that have both strong public good characteristics and that are used in public and private sector research.
TextSentencer_T76 14321-14478 Sentence denotes Because of this double feature, TS are suitable candidates for analysing the impact of public and private interdependencies on the organisation of the PSMCs.
TextSentencer_T76 14321-14478 Sentence denotes Because of this double feature, TS are suitable candidates for analysing the impact of public and private interdependencies on the organisation of the PSMCs.
TextSentencer_T76 14321-14478 Sentence denotes Because of this double feature, TS are suitable candidates for analysing the impact of public and private interdependencies on the organisation of the PSMCs.
TextSentencer_T77 14479-14661 Sentence denotes 4 More specifically, TS refer to microbes that are the reference strains used for taxonomic purposes and as such they are subject to strict quality management and are well described.
TextSentencer_T77 14479-14661 Sentence denotes 4 More specifically, TS refer to microbes that are the reference strains used for taxonomic purposes and as such they are subject to strict quality management and are well described.
TextSentencer_T77 14479-14661 Sentence denotes 4 More specifically, TS refer to microbes that are the reference strains used for taxonomic purposes and as such they are subject to strict quality management and are well described.
TextSentencer_T78 14662-14925 Sentence denotes TS are important building blocks for knowledge accumulation since they constitute the reference library against which any new microbial species has to be compared in order to certify their novelty, hence being a particularly vital tool for knowledge accumulation.
TextSentencer_T78 14662-14925 Sentence denotes TS are important building blocks for knowledge accumulation since they constitute the reference library against which any new microbial species has to be compared in order to certify their novelty, hence being a particularly vital tool for knowledge accumulation.
TextSentencer_T78 14662-14925 Sentence denotes TS are important building blocks for knowledge accumulation since they constitute the reference library against which any new microbial species has to be compared in order to certify their novelty, hence being a particularly vital tool for knowledge accumulation.
TextSentencer_T79 14926-15133 Sentence denotes While typically TS holdings are important in taxonomic collections which specialise in building a reference library, research collections also need a basic stock of TS as part of their overall holdings (c.f.
TextSentencer_T79 14926-15133 Sentence denotes While typically TS holdings are important in taxonomic collections which specialise in building a reference library, research collections also need a basic stock of TS as part of their overall holdings (c.f.
TextSentencer_T79 14926-15133 Sentence denotes While typically TS holdings are important in taxonomic collections which specialise in building a reference library, research collections also need a basic stock of TS as part of their overall holdings (c.f.
TextSentencer_T80 15134-15144 Sentence denotes Table 2 ).
TextSentencer_T80 15134-15144 Sentence denotes Table 2 ).
TextSentencer_T80 15134-15144 Sentence denotes Table 2 ).
TextSentencer_T81 15145-15243 Sentence denotes Further, while some collections were created with the explicit aim of having many TS (Smith, Pers.
TextSentencer_T81 15145-15243 Sentence denotes Further, while some collections were created with the explicit aim of having many TS (Smith, Pers.
TextSentencer_T81 15145-15243 Sentence denotes Further, while some collections were created with the explicit aim of having many TS (Smith, Pers.
TextSentencer_T82 15244-15448 Sentence denotes Comm.) , researchers often prefer to deposit their TS in other high profile research oriented collections, which do not specialise only in TS, as it gives prestige and higher diffusion for the researcher.
TextSentencer_T82 15244-15448 Sentence denotes Comm.) , researchers often prefer to deposit their TS in other high profile research oriented collections, which do not specialise only in TS, as it gives prestige and higher diffusion for the researcher.
TextSentencer_T82 15244-15448 Sentence denotes Comm.) , researchers often prefer to deposit their TS in other high profile research oriented collections, which do not specialise only in TS, as it gives prestige and higher diffusion for the researcher.
TextSentencer_T83 15449-15621 Sentence denotes Characterising TS as public goods, with both public sector and private sector users, has some important implications to understand the drivers of conservation in the PMSCs.
TextSentencer_T83 15449-15621 Sentence denotes Characterising TS as public goods, with both public sector and private sector users, has some important implications to understand the drivers of conservation in the PMSCs.
TextSentencer_T83 15449-15621 Sentence denotes Characterising TS as public goods, with both public sector and private sector users, has some important implications to understand the drivers of conservation in the PMSCs.
TextSentencer_T84 15622-15761 Sentence denotes TS consist of both the biological resource and of well documented information about their properties, such as reactivity with cancer cells.
TextSentencer_T84 15622-15761 Sentence denotes TS consist of both the biological resource and of well documented information about their properties, such as reactivity with cancer cells.
TextSentencer_T84 15622-15761 Sentence denotes TS consist of both the biological resource and of well documented information about their properties, such as reactivity with cancer cells.
TextSentencer_T85 15762-15935 Sentence denotes Hence, TS can be regarded as a hybrid material/ informational good, with public good characteristics associated both to the material itself and to the informational content.
TextSentencer_T85 15762-15935 Sentence denotes Hence, TS can be regarded as a hybrid material/ informational good, with public good characteristics associated both to the material itself and to the informational content.
TextSentencer_T85 15762-15935 Sentence denotes Hence, TS can be regarded as a hybrid material/ informational good, with public good characteristics associated both to the material itself and to the informational content.
TextSentencer_T86 15936-16150 Sentence denotes As biological resources, TS hold properties that are similar to those of a public good, since TS are characterised by relatively low rivalry in use since a similar strain can be cultivated from the original strain.
TextSentencer_T86 15936-16150 Sentence denotes As biological resources, TS hold properties that are similar to those of a public good, since TS are characterised by relatively low rivalry in use since a similar strain can be cultivated from the original strain.
TextSentencer_T86 15936-16150 Sentence denotes As biological resources, TS hold properties that are similar to those of a public good, since TS are characterised by relatively low rivalry in use since a similar strain can be cultivated from the original strain.
TextSentencer_T87 16151-16270 Sentence denotes 5 The information content of TS is of course non rival in the sense that usage does not reduce the information content.
TextSentencer_T87 16151-16270 Sentence denotes 5 The information content of TS is of course non rival in the sense that usage does not reduce the information content.
TextSentencer_T87 16151-16270 Sentence denotes 5 The information content of TS is of course non rival in the sense that usage does not reduce the information content.
TextSentencer_T88 16271-16518 Sentence denotes While their biological component is characterised by relatively low cost of exclusion since access is conditioned on consent from the holder of the TS, such as a PSMC, the information content related to the properties of TS has very low exclusion.
TextSentencer_T88 16271-16518 Sentence denotes While their biological component is characterised by relatively low cost of exclusion since access is conditioned on consent from the holder of the TS, such as a PSMC, the information content related to the properties of TS has very low exclusion.
TextSentencer_T88 16271-16518 Sentence denotes While their biological component is characterised by relatively low cost of exclusion since access is conditioned on consent from the holder of the TS, such as a PSMC, the information content related to the properties of TS has very low exclusion.
TextSentencer_T89 16519-16721 Sentence denotes That is, in order to achieve a broad diffusion and to capture coordination benefits, information content of TS is placed in the public domain, such as in scientific journals and PSMCs' internet portals.
TextSentencer_T89 16519-16721 Sentence denotes That is, in order to achieve a broad diffusion and to capture coordination benefits, information content of TS is placed in the public domain, such as in scientific journals and PSMCs' internet portals.
TextSentencer_T89 16519-16721 Sentence denotes That is, in order to achieve a broad diffusion and to capture coordination benefits, information content of TS is placed in the public domain, such as in scientific journals and PSMCs' internet portals.
TextSentencer_T90 16722-16885 Sentence denotes Since TS are used to enhance search for useful properties in other microbes, broad diffusion of the information content of TS is central to knowledge accumulation.
TextSentencer_T90 16722-16885 Sentence denotes Since TS are used to enhance search for useful properties in other microbes, broad diffusion of the information content of TS is central to knowledge accumulation.
TextSentencer_T90 16722-16885 Sentence denotes Since TS are used to enhance search for useful properties in other microbes, broad diffusion of the information content of TS is central to knowledge accumulation.
TextSentencer_T91 16886-16893 Sentence denotes Source:
TextSentencer_T91 16886-16893 Sentence denotes Source:
TextSentencer_T91 16886-16893 Sentence denotes Source:
TextSentencer_T92 16894-16947 Sentence denotes Own elaboration, typology based on Scott Stern, Pers.
TextSentencer_T92 16894-16947 Sentence denotes Own elaboration, typology based on Scott Stern, Pers.
TextSentencer_T92 16894-16947 Sentence denotes Own elaboration, typology based on Scott Stern, Pers.
TextSentencer_T93 16948-16974 Sentence denotes Comm. and own survey data.
TextSentencer_T93 16948-16974 Sentence denotes Comm. and own survey data.
TextSentencer_T93 16948-16974 Sentence denotes Comm. and own survey data.
TextSentencer_T94 16975-17211 Sentence denotes 3 However, at present, both the extension of the intellectual property regime over genetic resources and the supply channels in the life sciences has only had a marginal impact on the public availability of micro-organisms in the PSMCs.
TextSentencer_T94 16975-17211 Sentence denotes 3 However, at present, both the extension of the intellectual property regime over genetic resources and the supply channels in the life sciences has only had a marginal impact on the public availability of micro-organisms in the PSMCs.
TextSentencer_T94 16975-17211 Sentence denotes 3 However, at present, both the extension of the intellectual property regime over genetic resources and the supply channels in the life sciences has only had a marginal impact on the public availability of micro-organisms in the PSMCs.
TextSentencer_T95 17212-17530 Sentence denotes Most patents on micro-organisms are patents on methods and processes (Oldham, 2005) , with the notable exception of genetically modified microorganisms that are not part of the public holdings of the PSMCs, but are mostly deposited in the International Patent Deposit Authorities established under the Budapest treaty.
TextSentencer_T95 17212-17530 Sentence denotes Most patents on micro-organisms are patents on methods and processes (Oldham, 2005) , with the notable exception of genetically modified microorganisms that are not part of the public holdings of the PSMCs, but are mostly deposited in the International Patent Deposit Authorities established under the Budapest treaty.
TextSentencer_T95 17212-17530 Sentence denotes Most patents on micro-organisms are patents on methods and processes (Oldham, 2005) , with the notable exception of genetically modified microorganisms that are not part of the public holdings of the PSMCs, but are mostly deposited in the International Patent Deposit Authorities established under the Budapest treaty.
TextSentencer_T96 17531-17729 Sentence denotes 4 Type strains share these two features with the so-called model organisms, and have the additional advantage of being especially well documented, which allows a more in depth quantitative analysis.
TextSentencer_T96 17531-17729 Sentence denotes 4 Type strains share these two features with the so-called model organisms, and have the additional advantage of being especially well documented, which allows a more in depth quantitative analysis.
TextSentencer_T96 17531-17729 Sentence denotes 4 Type strains share these two features with the so-called model organisms, and have the additional advantage of being especially well documented, which allows a more in depth quantitative analysis.
TextSentencer_T97 17730-17809 Sentence denotes 5 In fact, once a copy of the TS is obtained, it can be reproduced at low cost.
TextSentencer_T97 17730-17809 Sentence denotes 5 In fact, once a copy of the TS is obtained, it can be reproduced at low cost.
TextSentencer_T97 17730-17809 Sentence denotes 5 In fact, once a copy of the TS is obtained, it can be reproduced at low cost.
TextSentencer_T98 17810-18241 Sentence denotes For example, in Europe the broader dissemination (and thus lower rivalry in use) of TS is reflected by the fact that identical copies of a given TS can be found in up to eight collections, while identical copies of non-TS are held in only 1.2 collections on average (Personal communication, June 2007, Peter Dawyndt; analysis done with the Straininfo Bioportal software for a subset of the major international culture collections).
TextSentencer_T98 17810-18241 Sentence denotes For example, in Europe the broader dissemination (and thus lower rivalry in use) of TS is reflected by the fact that identical copies of a given TS can be found in up to eight collections, while identical copies of non-TS are held in only 1.2 collections on average (Personal communication, June 2007, Peter Dawyndt; analysis done with the Straininfo Bioportal software for a subset of the major international culture collections).
TextSentencer_T98 17810-18241 Sentence denotes For example, in Europe the broader dissemination (and thus lower rivalry in use) of TS is reflected by the fact that identical copies of a given TS can be found in up to eight collections, while identical copies of non-TS are held in only 1.2 collections on average (Personal communication, June 2007, Peter Dawyndt; analysis done with the Straininfo Bioportal software for a subset of the major international culture collections).
TextSentencer_T99 18242-18630 Sentence denotes The economics literature has highlighted the important role that search has, for the identification of useful compounds regarding in situ biodiversity conservation and bioprospecting activities (Simpson et al., 1996; Rausser and Small, 2000; Simpson, 2002; Goeschl and Swanson, 2007) , as well as ex situ conservation (Evenson and Kislev, 1976; Gollin et al., 2000; Visser et al., 2000) .
TextSentencer_T99 18242-18630 Sentence denotes The economics literature has highlighted the important role that search has, for the identification of useful compounds regarding in situ biodiversity conservation and bioprospecting activities (Simpson et al., 1996; Rausser and Small, 2000; Simpson, 2002; Goeschl and Swanson, 2007) , as well as ex situ conservation (Evenson and Kislev, 1976; Gollin et al., 2000; Visser et al., 2000) .
TextSentencer_T99 18242-18630 Sentence denotes The economics literature has highlighted the important role that search has, for the identification of useful compounds regarding in situ biodiversity conservation and bioprospecting activities (Simpson et al., 1996; Rausser and Small, 2000; Simpson, 2002; Goeschl and Swanson, 2007) , as well as ex situ conservation (Evenson and Kislev, 1976; Gollin et al., 2000; Visser et al., 2000) .
TextSentencer_T100 18631-18917 Sentence denotes This literature provides insights as to why on the one hand the industry has an incentive to invest in applied research and product development, but on the other hand, the industry would not invest sufficiently (from a social point of view) in TS due to its public good characteristics.
TextSentencer_T100 18631-18917 Sentence denotes This literature provides insights as to why on the one hand the industry has an incentive to invest in applied research and product development, but on the other hand, the industry would not invest sufficiently (from a social point of view) in TS due to its public good characteristics.
TextSentencer_T100 18631-18917 Sentence denotes This literature provides insights as to why on the one hand the industry has an incentive to invest in applied research and product development, but on the other hand, the industry would not invest sufficiently (from a social point of view) in TS due to its public good characteristics.
TextSentencer_T101 18918-19066 Sentence denotes Hence, it can be expected that support in this basic infrastructure by public bodies such as governments is necessary to stimulate investment in TS.
TextSentencer_T101 18918-19066 Sentence denotes Hence, it can be expected that support in this basic infrastructure by public bodies such as governments is necessary to stimulate investment in TS.
TextSentencer_T101 18918-19066 Sentence denotes Hence, it can be expected that support in this basic infrastructure by public bodies such as governments is necessary to stimulate investment in TS.
TextSentencer_T102 19067-19230 Sentence denotes Similar findings are expressed in the literature on innovation and public goods (Nordhaus, 1969; Evenson and Kislev, 1976; Jaffe, 1986; Cornes and Sandler, 1996) .
TextSentencer_T102 19067-19230 Sentence denotes Similar findings are expressed in the literature on innovation and public goods (Nordhaus, 1969; Evenson and Kislev, 1976; Jaffe, 1986; Cornes and Sandler, 1996) .
TextSentencer_T102 19067-19230 Sentence denotes Similar findings are expressed in the literature on innovation and public goods (Nordhaus, 1969; Evenson and Kislev, 1976; Jaffe, 1986; Cornes and Sandler, 1996) .
TextSentencer_T103 19231-19505 Sentence denotes It can be expected that PSMCs which specialise in TS holdings will depend on at least some public research funding, even if one might also expect an important part of co-funding by the private sector, as these are important users of the TS and the expertise related to them.
TextSentencer_T103 19231-19505 Sentence denotes It can be expected that PSMCs which specialise in TS holdings will depend on at least some public research funding, even if one might also expect an important part of co-funding by the private sector, as these are important users of the TS and the expertise related to them.
TextSentencer_T103 19231-19505 Sentence denotes It can be expected that PSMCs which specialise in TS holdings will depend on at least some public research funding, even if one might also expect an important part of co-funding by the private sector, as these are important users of the TS and the expertise related to them.
TextSentencer_T104 19506-19632 Sentence denotes This would be the case of infrastructure oriented collections specialising in taxonomic type strains as described in Table 1 .
TextSentencer_T104 19506-19632 Sentence denotes This would be the case of infrastructure oriented collections specialising in taxonomic type strains as described in Table 1 .
TextSentencer_T104 19506-19632 Sentence denotes This would be the case of infrastructure oriented collections specialising in taxonomic type strains as described in Table 1 .
TextSentencer_T105 19633-19814 Sentence denotes At the same time it can be expected that research collections (cf. Table 1 ) will to a certain extent invest in TS but will also develop a broader portfolio of biological materials.
TextSentencer_T105 19633-19814 Sentence denotes At the same time it can be expected that research collections (cf. Table 1 ) will to a certain extent invest in TS but will also develop a broader portfolio of biological materials.
TextSentencer_T105 19633-19814 Sentence denotes At the same time it can be expected that research collections (cf. Table 1 ) will to a certain extent invest in TS but will also develop a broader portfolio of biological materials.
TextSentencer_T106 19815-19881 Sentence denotes In this case a more diversified funding strategy will be required.
TextSentencer_T106 19815-19881 Sentence denotes In this case a more diversified funding strategy will be required.
TextSentencer_T106 19815-19881 Sentence denotes In this case a more diversified funding strategy will be required.
TextSentencer_T107 19882-20029 Sentence denotes For such research collections, moderate support from the government and the private sector for TS conservation is expected to be important as well.
TextSentencer_T107 19882-20029 Sentence denotes For such research collections, moderate support from the government and the private sector for TS conservation is expected to be important as well.
TextSentencer_T107 19882-20029 Sentence denotes For such research collections, moderate support from the government and the private sector for TS conservation is expected to be important as well.
TextSentencer_T108 20030-20295 Sentence denotes But, in addition, basic research funding will be required for the publication and basic research related deposits, whether through direct funding or indirectly through basic income stream such as the formation of a patent deposit authority or project based funding.
TextSentencer_T108 20030-20295 Sentence denotes But, in addition, basic research funding will be required for the publication and basic research related deposits, whether through direct funding or indirectly through basic income stream such as the formation of a patent deposit authority or project based funding.
TextSentencer_T108 20030-20295 Sentence denotes But, in addition, basic research funding will be required for the publication and basic research related deposits, whether through direct funding or indirectly through basic income stream such as the formation of a patent deposit authority or project based funding.
TextSentencer_T109 20296-20548 Sentence denotes Moreover, in response to the new opportunities from biotechnology and genomics, culture collections have increasingly diversified their activities, by adopting commercial approaches to generate new income from cost-sharing with industry (Stern, 2004) .
TextSentencer_T109 20296-20548 Sentence denotes Moreover, in response to the new opportunities from biotechnology and genomics, culture collections have increasingly diversified their activities, by adopting commercial approaches to generate new income from cost-sharing with industry (Stern, 2004) .
TextSentencer_T109 20296-20548 Sentence denotes Moreover, in response to the new opportunities from biotechnology and genomics, culture collections have increasingly diversified their activities, by adopting commercial approaches to generate new income from cost-sharing with industry (Stern, 2004) .
TextSentencer_T110 20549-20730 Sentence denotes Combining their basic research and infrastructure functions with the promotion of downstream applications, by providing services to industry, seems like trying to square the circle.
TextSentencer_T110 20549-20730 Sentence denotes Combining their basic research and infrastructure functions with the promotion of downstream applications, by providing services to industry, seems like trying to square the circle.
TextSentencer_T110 20549-20730 Sentence denotes Combining their basic research and infrastructure functions with the promotion of downstream applications, by providing services to industry, seems like trying to square the circle.
TextSentencer_T111 20731-21174 Sentence denotes However, this combination of basic research perspectives and user-inspired applications is precisely what has characterised the recent history of the contemporary life sciences more generally (Cook-Deegan and Dedeurwaerdere, 2006) , where for example new insights in genomics have contributed to our basic understanding of biological processes while at the same time leading to new applications in genetic diagnostics and rational drug design.
TextSentencer_T111 20731-21174 Sentence denotes However, this combination of basic research perspectives and user-inspired applications is precisely what has characterised the recent history of the contemporary life sciences more generally (Cook-Deegan and Dedeurwaerdere, 2006) , where for example new insights in genomics have contributed to our basic understanding of biological processes while at the same time leading to new applications in genetic diagnostics and rational drug design.
TextSentencer_T111 20731-21174 Sentence denotes However, this combination of basic research perspectives and user-inspired applications is precisely what has characterised the recent history of the contemporary life sciences more generally (Cook-Deegan and Dedeurwaerdere, 2006) , where for example new insights in genomics have contributed to our basic understanding of biological processes while at the same time leading to new applications in genetic diagnostics and rational drug design.
TextSentencer_T112 21175-21481 Sentence denotes 6 Producing knowledge in this intermediary field implies looking beyond the norms and practices of basic science and taxonomic communities, and requires support for building new collaborations that cross the boundaries between basic science, conservation and commercial and non-commercial user communities.
TextSentencer_T112 21175-21481 Sentence denotes 6 Producing knowledge in this intermediary field implies looking beyond the norms and practices of basic science and taxonomic communities, and requires support for building new collaborations that cross the boundaries between basic science, conservation and commercial and non-commercial user communities.
TextSentencer_T112 21175-21481 Sentence denotes 6 Producing knowledge in this intermediary field implies looking beyond the norms and practices of basic science and taxonomic communities, and requires support for building new collaborations that cross the boundaries between basic science, conservation and commercial and non-commercial user communities.
TextSentencer_T113 21482-21607 Sentence denotes This latter situation characterises both the infrastructure oriented and the specialised industry collections (cf. Table 1 ).
TextSentencer_T113 21482-21607 Sentence denotes This latter situation characterises both the infrastructure oriented and the specialised industry collections (cf. Table 1 ).
TextSentencer_T113 21482-21607 Sentence denotes This latter situation characterises both the infrastructure oriented and the specialised industry collections (cf. Table 1 ).
TextSentencer_T114 21608-21850 Sentence denotes In contrast, in the case of basic research oriented collections, where private sector users have lesser incentive to contribute to its public infrastructure functions, a certain level of public support is required to maintain these functions.
TextSentencer_T114 21608-21850 Sentence denotes In contrast, in the case of basic research oriented collections, where private sector users have lesser incentive to contribute to its public infrastructure functions, a certain level of public support is required to maintain these functions.
TextSentencer_T114 21608-21850 Sentence denotes In contrast, in the case of basic research oriented collections, where private sector users have lesser incentive to contribute to its public infrastructure functions, a certain level of public support is required to maintain these functions.
TextSentencer_T115 21851-22133 Sentence denotes Our complementary question is therefore if and to what extent low public investment, as measured by low as opposed to high public funding, is correlated with the PSMC's industry orientation in terms of the proportion of microorganisms supplied to industry as opposed to other users.
TextSentencer_T115 21851-22133 Sentence denotes Our complementary question is therefore if and to what extent low public investment, as measured by low as opposed to high public funding, is correlated with the PSMC's industry orientation in terms of the proportion of microorganisms supplied to industry as opposed to other users.
TextSentencer_T115 21851-22133 Sentence denotes Our complementary question is therefore if and to what extent low public investment, as measured by low as opposed to high public funding, is correlated with the PSMC's industry orientation in terms of the proportion of microorganisms supplied to industry as opposed to other users.
TextSentencer_T116 22134-22290 Sentence denotes The links between the PSMCs' microeconomic, institutional and organisational context, their conservation and distribution pattern are illustrated in Fig. 1.
TextSentencer_T116 22134-22290 Sentence denotes The links between the PSMCs' microeconomic, institutional and organisational context, their conservation and distribution pattern are illustrated in Fig. 1.
TextSentencer_T116 22134-22290 Sentence denotes The links between the PSMCs' microeconomic, institutional and organisational context, their conservation and distribution pattern are illustrated in Fig. 1.
TextSentencer_T117 22292-22574 Sentence denotes A population frame of 499 PSMCs which were members in 2005 of the World Federation of Culture Collections (WFCC) or the United Nations Educational Scientific and Cultural Organisation Microbial Resources Network (MIRCEN) was used to conduct a world-wide survey on a sample of PSMCs.
TextSentencer_T117 22292-22574 Sentence denotes A population frame of 499 PSMCs which were members in 2005 of the World Federation of Culture Collections (WFCC) or the United Nations Educational Scientific and Cultural Organisation Microbial Resources Network (MIRCEN) was used to conduct a world-wide survey on a sample of PSMCs.
TextSentencer_T117 22292-22574 Sentence denotes A population frame of 499 PSMCs which were members in 2005 of the World Federation of Culture Collections (WFCC) or the United Nations Educational Scientific and Cultural Organisation Microbial Resources Network (MIRCEN) was used to conduct a world-wide survey on a sample of PSMCs.
TextSentencer_T118 22575-22648 Sentence denotes Further details of the method are presented in the electronic supplement.
TextSentencer_T118 22575-22648 Sentence denotes Further details of the method are presented in the electronic supplement.
TextSentencer_T118 22575-22648 Sentence denotes Further details of the method are presented in the electronic supplement.
TextSentencer_T119 22649-22895 Sentence denotes A total of 155 collections responded to the main questionnaire from which a final sample size of 103 observations with complete data were used in the analysis (the electronic supplement provides further details on the materials and methods used).
TextSentencer_T119 22649-22895 Sentence denotes A total of 155 collections responded to the main questionnaire from which a final sample size of 103 observations with complete data were used in the analysis (the electronic supplement provides further details on the materials and methods used).
TextSentencer_T119 22649-22895 Sentence denotes A total of 155 collections responded to the main questionnaire from which a final sample size of 103 observations with complete data were used in the analysis (the electronic supplement provides further details on the materials and methods used).
TextSentencer_T120 22896-23284 Sentence denotes We simultaneously assess (1) the role played by public funding in the strategy of PSMCs regarding their supply of TS (conservation focus of publicly available micro-organisms used both in public sector and private sector research) as well as (2) A second sub model (Eq. (2)) to test if such hybrid organisational model also is correlated with a stronger industry orientation of the PSMCs.
TextSentencer_T120 22896-23284 Sentence denotes We simultaneously assess (1) the role played by public funding in the strategy of PSMCs regarding their supply of TS (conservation focus of publicly available micro-organisms used both in public sector and private sector research) as well as (2) A second sub model (Eq. (2)) to test if such hybrid organisational model also is correlated with a stronger industry orientation of the PSMCs.
TextSentencer_T120 22896-23284 Sentence denotes We simultaneously assess (1) the role played by public funding in the strategy of PSMCs regarding their supply of TS (conservation focus of publicly available micro-organisms used both in public sector and private sector research) as well as (2) A second sub model (Eq. (2)) to test if such hybrid organisational model also is correlated with a stronger industry orientation of the PSMCs.
TextSentencer_T121 23285-23351 Sentence denotes The electronic supplement provides further details of the results.
TextSentencer_T121 23285-23351 Sentence denotes The electronic supplement provides further details of the results.
TextSentencer_T121 23285-23351 Sentence denotes The electronic supplement provides further details of the results.
TextSentencer_T122 23352-23554 Sentence denotes The results (Table 3) confirm interdependence between the PSMCs' (a) decisions in specialising in microbes which have public good properties (i.e., TS) and their (b) profile of distribution to industry.
TextSentencer_T122 23352-23554 Sentence denotes The results (Table 3) confirm interdependence between the PSMCs' (a) decisions in specialising in microbes which have public good properties (i.e., TS) and their (b) profile of distribution to industry.
TextSentencer_T122 23352-23554 Sentence denotes The results (Table 3) confirm interdependence between the PSMCs' (a) decisions in specialising in microbes which have public good properties (i.e., TS) and their (b) profile of distribution to industry.
TextSentencer_T123 23555-23690 Sentence denotes Specifically, specialisation in TS is positively correlated with an overall provision of microbial strains (TS and non TS) to industry.
TextSentencer_T123 23555-23690 Sentence denotes Specifically, specialisation in TS is positively correlated with an overall provision of microbial strains (TS and non TS) to industry.
TextSentencer_T123 23555-23690 Sentence denotes Specifically, specialisation in TS is positively correlated with an overall provision of microbial strains (TS and non TS) to industry.
TextSentencer_T124 23691-23929 Sentence denotes The results of the conservation strategy sub model provide information about the main question regarding the effect that public or mixed funding strategies has on conservation strategy of publicly available research resources (TS supply).
TextSentencer_T124 23691-23929 Sentence denotes The results of the conservation strategy sub model provide information about the main question regarding the effect that public or mixed funding strategies has on conservation strategy of publicly available research resources (TS supply).
TextSentencer_T124 23691-23929 Sentence denotes The results of the conservation strategy sub model provide information about the main question regarding the effect that public or mixed funding strategies has on conservation strategy of publicly available research resources (TS supply).
TextSentencer_T125 23930-24217 Sentence denotes We find that on the one hand similar proportions of public and private funding (the variable SUPPORTMEDIUM) has a statistically significant and positive coefficient and on the other hand high public funding (the variable SUPPORTHIGH) has a statistically significant negative coefficient.
TextSentencer_T125 23930-24217 Sentence denotes We find that on the one hand similar proportions of public and private funding (the variable SUPPORTMEDIUM) has a statistically significant and positive coefficient and on the other hand high public funding (the variable SUPPORTHIGH) has a statistically significant negative coefficient.
TextSentencer_T125 23930-24217 Sentence denotes We find that on the one hand similar proportions of public and private funding (the variable SUPPORTMEDIUM) has a statistically significant and positive coefficient and on the other hand high public funding (the variable SUPPORTHIGH) has a statistically significant negative coefficient.
TextSentencer_T126 24218-24282 Sentence denotes This indicates a role of private funding in the provision of TS.
TextSentencer_T126 24218-24282 Sentence denotes This indicates a role of private funding in the provision of TS.
TextSentencer_T126 24218-24282 Sentence denotes This indicates a role of private funding in the provision of TS.
TextSentencer_T127 24283-24319 Sentence denotes However, this is a nonlinear effect.
TextSentencer_T127 24283-24319 Sentence denotes However, this is a nonlinear effect.
TextSentencer_T127 24283-24319 Sentence denotes However, this is a nonlinear effect.
TextSentencer_T128 24320-24462 Sentence denotes The data suggest that it is a mix of publicprivate funding strategy that characterises those collections that may prioritise investment in TS.
TextSentencer_T128 24320-24462 Sentence denotes The data suggest that it is a mix of publicprivate funding strategy that characterises those collections that may prioritise investment in TS.
TextSentencer_T128 24320-24462 Sentence denotes The data suggest that it is a mix of publicprivate funding strategy that characterises those collections that may prioritise investment in TS.
TextSentencer_T129 24463-24587 Sentence denotes This result is consistent with previous conclusions from crop breeding analyses (Gollin et al., 2000; Visser et al., 2000) .
TextSentencer_T129 24463-24587 Sentence denotes This result is consistent with previous conclusions from crop breeding analyses (Gollin et al., 2000; Visser et al., 2000) .
TextSentencer_T129 24463-24587 Sentence denotes This result is consistent with previous conclusions from crop breeding analyses (Gollin et al., 2000; Visser et al., 2000) .
TextSentencer_T130 24588-24801 Sentence denotes In line with public good theory as well as search theory, society relies on public investment for the provision of diversity of biological research materials that otherwise would be underprovided by markets alone.
TextSentencer_T130 24588-24801 Sentence denotes In line with public good theory as well as search theory, society relies on public investment for the provision of diversity of biological research materials that otherwise would be underprovided by markets alone.
TextSentencer_T130 24588-24801 Sentence denotes In line with public good theory as well as search theory, society relies on public investment for the provision of diversity of biological research materials that otherwise would be underprovided by markets alone.
TextSentencer_T131 24802-24865 Sentence denotes The role of industry is probably to provide cost-sharing to the
TextSentencer_T131 24802-24865 Sentence denotes The role of industry is probably to provide cost-sharing to the
TextSentencer_T131 24802-24865 Sentence denotes The role of industry is probably to provide cost-sharing to the
TextSentencer_T132 24867-25040 Sentence denotes (2) e n v i r o n m e n t a l s c i e n c e & p o l i c y 3 3 ( 2 0 1 3 ) 1 9 -2 7 costly enterprise of holding such microbes, as a means to secure access to such resources.
TextSentencer_T132 24867-25040 Sentence denotes (2) e n v i r o n m e n t a l s c i e n c e & p o l i c y 3 3 ( 2 0 1 3 ) 1 9 -2 7 costly enterprise of holding such microbes, as a means to secure access to such resources.
TextSentencer_T132 24867-25040 Sentence denotes (2) e n v i r o n m e n t a l s c i e n c e & p o l i c y 3 3 ( 2 0 1 3 ) 1 9 -2 7 costly enterprise of holding such microbes, as a means to secure access to such resources.
TextSentencer_T133 25041-25417 Sentence denotes Regarding the control variables, strong property rights (the variable PR) has a statistically significant and positive effect on conservation outcomes, suggesting that a more formal approach to the acquisition and distribution of microbes, i.e. with a formal legal mechanism to control the use of the resource, is associated with a higher ratio of TS in collections' holdings.
TextSentencer_T133 25041-25417 Sentence denotes Regarding the control variables, strong property rights (the variable PR) has a statistically significant and positive effect on conservation outcomes, suggesting that a more formal approach to the acquisition and distribution of microbes, i.e. with a formal legal mechanism to control the use of the resource, is associated with a higher ratio of TS in collections' holdings.
TextSentencer_T133 25041-25417 Sentence denotes Regarding the control variables, strong property rights (the variable PR) has a statistically significant and positive effect on conservation outcomes, suggesting that a more formal approach to the acquisition and distribution of microbes, i.e. with a formal legal mechanism to control the use of the resource, is associated with a higher ratio of TS in collections' holdings.
TextSentencer_T134 25418-25566 Sentence denotes Size of the collection is, as expected, negatively associated with the proportion of TS conservation, hence suggesting the expected dilution effect.
TextSentencer_T134 25418-25566 Sentence denotes Size of the collection is, as expected, negatively associated with the proportion of TS conservation, hence suggesting the expected dilution effect.
TextSentencer_T134 25418-25566 Sentence denotes Size of the collection is, as expected, negatively associated with the proportion of TS conservation, hence suggesting the expected dilution effect.
TextSentencer_T135 25567-25757 Sentence denotes In addition, the inflow of microbes is positively associated with conservation outcomes indicating that PSMCs sourcing strains from other microbe collections may be more oriented towards TS.
TextSentencer_T135 25567-25757 Sentence denotes In addition, the inflow of microbes is positively associated with conservation outcomes indicating that PSMCs sourcing strains from other microbe collections may be more oriented towards TS.
TextSentencer_T135 25567-25757 Sentence denotes In addition, the inflow of microbes is positively associated with conservation outcomes indicating that PSMCs sourcing strains from other microbe collections may be more oriented towards TS.
TextSentencer_T136 25758-25856 Sentence denotes Location of collections in, as opposed to outside, OECD countries does not affect the TS strategy.
TextSentencer_T136 25758-25856 Sentence denotes Location of collections in, as opposed to outside, OECD countries does not affect the TS strategy.
TextSentencer_T136 25758-25856 Sentence denotes Location of collections in, as opposed to outside, OECD countries does not affect the TS strategy.
TextSentencer_T137 25857-25994 Sentence denotes This might be because the international exchanges of microbes amongst PSMCs, including TS, dilute the effect of domestic industry demand.
TextSentencer_T137 25857-25994 Sentence denotes This might be because the international exchanges of microbes amongst PSMCs, including TS, dilute the effect of domestic industry demand.
TextSentencer_T137 25857-25994 Sentence denotes This might be because the international exchanges of microbes amongst PSMCs, including TS, dilute the effect of domestic industry demand.
TextSentencer_T138 25995-26048 Sentence denotes Nor is location in the USA statistically significant.
TextSentencer_T138 25995-26048 Sentence denotes Nor is location in the USA statistically significant.
TextSentencer_T138 25995-26048 Sentence denotes Nor is location in the USA statistically significant.
TextSentencer_T139 26049-26160 Sentence denotes Additionally, we can see that a formal transfer mode by charging a fee is associated with specialisation in TS.
TextSentencer_T139 26049-26160 Sentence denotes Additionally, we can see that a formal transfer mode by charging a fee is associated with specialisation in TS.
TextSentencer_T139 26049-26160 Sentence denotes Additionally, we can see that a formal transfer mode by charging a fee is associated with specialisation in TS.
TextSentencer_T140 26161-26362 Sentence denotes To the extent that TS are public goods, as argued here, this result indicates that more business like ways of handling research materials have gained a strong influence in public good microbe holdings.
TextSentencer_T140 26161-26362 Sentence denotes To the extent that TS are public goods, as argued here, this result indicates that more business like ways of handling research materials have gained a strong influence in public good microbe holdings.
TextSentencer_T140 26161-26362 Sentence denotes To the extent that TS are public goods, as argued here, this result indicates that more business like ways of handling research materials have gained a strong influence in public good microbe holdings.
TextSentencer_T141 26363-26501 Sentence denotes The data also show that collections focusing on algae and fungi to less extent conserve TS, compared to collections specialising in yeast.
TextSentencer_T141 26363-26501 Sentence denotes The data also show that collections focusing on algae and fungi to less extent conserve TS, compared to collections specialising in yeast.
TextSentencer_T141 26363-26501 Sentence denotes The data also show that collections focusing on algae and fungi to less extent conserve TS, compared to collections specialising in yeast.
TextSentencer_T142 26502-26659 Sentence denotes In the second sub model, the coefficient for even proportions of public and private funding is statistically significant and with the expected positive sign.
TextSentencer_T142 26502-26659 Sentence denotes In the second sub model, the coefficient for even proportions of public and private funding is statistically significant and with the expected positive sign.
TextSentencer_T142 26502-26659 Sentence denotes In the second sub model, the coefficient for even proportions of public and private funding is statistically significant and with the expected positive sign.
TextSentencer_T143 26660-26711 Sentence denotes The same outcomes are shown for low public funding.
TextSentencer_T143 26660-26711 Sentence denotes The same outcomes are shown for low public funding.
TextSentencer_T143 26660-26711 Sentence denotes The same outcomes are shown for low public funding.
TextSentencer_T144 26712-26790 Sentence denotes The remaining funding variables do not have statistically significant effects.
TextSentencer_T144 26712-26790 Sentence denotes The remaining funding variables do not have statistically significant effects.
TextSentencer_T144 26712-26790 Sentence denotes The remaining funding variables do not have statistically significant effects.
TextSentencer_T145 26791-26870 Sentence denotes This reflects a diversified funding strategy for industry oriented collections.
TextSentencer_T145 26791-26870 Sentence denotes This reflects a diversified funding strategy for industry oriented collections.
TextSentencer_T145 26791-26870 Sentence denotes This reflects a diversified funding strategy for industry oriented collections.
TextSentencer_T146 26871-27064 Sentence denotes Specifically, such outcome indicates that a strong public service mandate, as reflected by heavy public funding, is associated with an orientation towards other users than the private industry.
TextSentencer_T146 26871-27064 Sentence denotes Specifically, such outcome indicates that a strong public service mandate, as reflected by heavy public funding, is associated with an orientation towards other users than the private industry.
TextSentencer_T146 26871-27064 Sentence denotes Specifically, such outcome indicates that a strong public service mandate, as reflected by heavy public funding, is associated with an orientation towards other users than the private industry.
TextSentencer_T147 27065-27223 Sentence denotes Notably, even if all PSMCs to some extent belong to the basic research infrastructure, at least half of the PSMCs in the dataset receive also private funding.
TextSentencer_T147 27065-27223 Sentence denotes Notably, even if all PSMCs to some extent belong to the basic research infrastructure, at least half of the PSMCs in the dataset receive also private funding.
TextSentencer_T147 27065-27223 Sentence denotes Notably, even if all PSMCs to some extent belong to the basic research infrastructure, at least half of the PSMCs in the dataset receive also private funding.
TextSentencer_T148 27224-27384 Sentence denotes Such costsharing appears to play an important role in conservation because it is associated with both large collections, and collections which specialise in TS.
TextSentencer_T148 27224-27384 Sentence denotes Such costsharing appears to play an important role in conservation because it is associated with both large collections, and collections which specialise in TS.
TextSentencer_T148 27224-27384 Sentence denotes Such costsharing appears to play an important role in conservation because it is associated with both large collections, and collections which specialise in TS.
TextSentencer_T149 27385-27464 Sentence denotes Among the control variables, property rights are not statistically significant.
TextSentencer_T149 27385-27464 Sentence denotes Among the control variables, property rights are not statistically significant.
TextSentencer_T149 27385-27464 Sentence denotes Among the control variables, property rights are not statistically significant.
TextSentencer_T150 27465-27608 Sentence denotes This may indicate that the use of MTAs is in no way exclusive for provision to industry but are in fact used also for provision to other users.
TextSentencer_T150 27465-27608 Sentence denotes This may indicate that the use of MTAs is in no way exclusive for provision to industry but are in fact used also for provision to other users.
TextSentencer_T150 27465-27608 Sentence denotes This may indicate that the use of MTAs is in no way exclusive for provision to industry but are in fact used also for provision to other users.
TextSentencer_T151 27609-27856 Sentence denotes As expected, the scale or size of the collection (the variable STOCK) and sourcing of microbes (the variable INFLOW) foremost included for the conservation regression have no meaningful statistically significant effect on the industry orientation.
TextSentencer_T151 27609-27856 Sentence denotes As expected, the scale or size of the collection (the variable STOCK) and sourcing of microbes (the variable INFLOW) foremost included for the conservation regression have no meaningful statistically significant effect on the industry orientation.
TextSentencer_T151 27609-27856 Sentence denotes As expected, the scale or size of the collection (the variable STOCK) and sourcing of microbes (the variable INFLOW) foremost included for the conservation regression have no meaningful statistically significant effect on the industry orientation.
TextSentencer_T152 27857-28114 Sentence denotes However, the variable denoting a higher relative provision of microbes to academia and hospitals (the variable FLOWACAD) is statistically significant and indicates that industry in contrast to other sectors have structurally different preferences and needs.
TextSentencer_T152 27857-28114 Sentence denotes However, the variable denoting a higher relative provision of microbes to academia and hospitals (the variable FLOWACAD) is statistically significant and indicates that industry in contrast to other sectors have structurally different preferences and needs.
TextSentencer_T152 27857-28114 Sentence denotes However, the variable denoting a higher relative provision of microbes to academia and hospitals (the variable FLOWACAD) is statistically significant and indicates that industry in contrast to other sectors have structurally different preferences and needs.
TextSentencer_T153 28115-28314 Sentence denotes For instance, it is not necessarily the case that whichever high demand for microbes from a PSMC, irrespective of the type of demander, signals that the collection also attracts demand from industry.
TextSentencer_T153 28115-28314 Sentence denotes For instance, it is not necessarily the case that whichever high demand for microbes from a PSMC, irrespective of the type of demander, signals that the collection also attracts demand from industry.
TextSentencer_T153 28115-28314 Sentence denotes For instance, it is not necessarily the case that whichever high demand for microbes from a PSMC, irrespective of the type of demander, signals that the collection also attracts demand from industry.
TextSentencer_T154 28315-28570 Sentence denotes Rather, more traditional users such as academia and hospitals may have different preferences than industry, related to issues such as institutional arrangements regarding microbe transfers or the content and quality of microbes and associated information.
TextSentencer_T154 28315-28570 Sentence denotes Rather, more traditional users such as academia and hospitals may have different preferences than industry, related to issues such as institutional arrangements regarding microbe transfers or the content and quality of microbes and associated information.
TextSentencer_T154 28315-28570 Sentence denotes Rather, more traditional users such as academia and hospitals may have different preferences than industry, related to issues such as institutional arrangements regarding microbe transfers or the content and quality of microbes and associated information.
TextSentencer_T155 28571-28854 Sentence denotes In contrast to the first sub model, location in either OECD (except for USA) or USA is statistically significant and suggest that PSMCs in countries with a high level of industrial development may be responding to industry demand by channelling some of their microbes to this sector.
TextSentencer_T155 28571-28854 Sentence denotes In contrast to the first sub model, location in either OECD (except for USA) or USA is statistically significant and suggest that PSMCs in countries with a high level of industrial development may be responding to industry demand by channelling some of their microbes to this sector.
TextSentencer_T155 28571-28854 Sentence denotes In contrast to the first sub model, location in either OECD (except for USA) or USA is statistically significant and suggest that PSMCs in countries with a high level of industrial development may be responding to industry demand by channelling some of their microbes to this sector.
TextSentencer_T156 28855-29126 Sentence denotes The data also indicate that charging a fee signals that the collection adopts a more formal microbe transfer regime and thus is also prepared to serve commercial clients through market oriented modes rather than the traditional informal reciprocity-based governance mode.
TextSentencer_T156 28855-29126 Sentence denotes The data also indicate that charging a fee signals that the collection adopts a more formal microbe transfer regime and thus is also prepared to serve commercial clients through market oriented modes rather than the traditional informal reciprocity-based governance mode.
TextSentencer_T156 28855-29126 Sentence denotes The data also indicate that charging a fee signals that the collection adopts a more formal microbe transfer regime and thus is also prepared to serve commercial clients through market oriented modes rather than the traditional informal reciprocity-based governance mode.
TextSentencer_T157 29127-29354 Sentence denotes Lastly, among the kind of microbial material conserved, only collections specialised on YEAST are associated with a stronger industry orientation, possibly due to the high use of yeast in the pharmaceutical and food industries.
TextSentencer_T157 29127-29354 Sentence denotes Lastly, among the kind of microbial material conserved, only collections specialised on YEAST are associated with a stronger industry orientation, possibly due to the high use of yeast in the pharmaceutical and food industries.
TextSentencer_T157 29127-29354 Sentence denotes Lastly, among the kind of microbial material conserved, only collections specialised on YEAST are associated with a stronger industry orientation, possibly due to the high use of yeast in the pharmaceutical and food industries.
TextSentencer_T158 29355-29484 Sentence denotes To sum up, the statistical analysis reveals that it would be misguided to describe PSMCs according to a public-private dichotomy.
TextSentencer_T158 29355-29484 Sentence denotes To sum up, the statistical analysis reveals that it would be misguided to describe PSMCs according to a public-private dichotomy.
TextSentencer_T158 29355-29484 Sentence denotes To sum up, the statistical analysis reveals that it would be misguided to describe PSMCs according to a public-private dichotomy.
TextSentencer_T159 29485-29823 Sentence denotes Instead the data reveal that it is more useful to study nuanced associations between management regime, e.g. source of influence from the funders and categories of users of microbes, and the economic instruments and compliance mechanisms used to manage microbe transactions, such as fees and formalised contractual distribution practices.
TextSentencer_T159 29485-29823 Sentence denotes Instead the data reveal that it is more useful to study nuanced associations between management regime, e.g. source of influence from the funders and categories of users of microbes, and the economic instruments and compliance mechanisms used to manage microbe transactions, such as fees and formalised contractual distribution practices.
TextSentencer_T159 29485-29823 Sentence denotes Instead the data reveal that it is more useful to study nuanced associations between management regime, e.g. source of influence from the funders and categories of users of microbes, and the economic instruments and compliance mechanisms used to manage microbe transactions, such as fees and formalised contractual distribution practices.
TextSentencer_T160 29824-30030 Sentence denotes To the best of our knowledge this paper addresses for the first time the factors, at the micro-economic level, affecting biological resource conservation by and transfers from ex situ microbial collections.
TextSentencer_T160 29824-30030 Sentence denotes To the best of our knowledge this paper addresses for the first time the factors, at the micro-economic level, affecting biological resource conservation by and transfers from ex situ microbial collections.
TextSentencer_T160 29824-30030 Sentence denotes To the best of our knowledge this paper addresses for the first time the factors, at the micro-economic level, affecting biological resource conservation by and transfers from ex situ microbial collections.
TextSentencer_T161 30031-30449 Sentence denotes Based on a unique world-wide survey of culture collections the paper provides novel insights about the way that public-service microbial collections constitute a highly heterogeneous group of organisations, how the evolving funding mechanisms relate to their conservation of publicly available microbial resources, and to the distribution patterns of microbial resources to private sector and public sector recipients.
TextSentencer_T161 30031-30449 Sentence denotes Based on a unique world-wide survey of culture collections the paper provides novel insights about the way that public-service microbial collections constitute a highly heterogeneous group of organisations, how the evolving funding mechanisms relate to their conservation of publicly available microbial resources, and to the distribution patterns of microbial resources to private sector and public sector recipients.
TextSentencer_T161 30031-30449 Sentence denotes Based on a unique world-wide survey of culture collections the paper provides novel insights about the way that public-service microbial collections constitute a highly heterogeneous group of organisations, how the evolving funding mechanisms relate to their conservation of publicly available microbial resources, and to the distribution patterns of microbial resources to private sector and public sector recipients.
TextSentencer_T162 30450-30657 Sentence denotes Moreover, in order to cast further light on the important question of private influence on public goods, microorganisms with particularly strong public good properties are contrasted to other microorganisms.
TextSentencer_T162 30450-30657 Sentence denotes Moreover, in order to cast further light on the important question of private influence on public goods, microorganisms with particularly strong public good properties are contrasted to other microorganisms.
TextSentencer_T162 30450-30657 Sentence denotes Moreover, in order to cast further light on the important question of private influence on public goods, microorganisms with particularly strong public good properties are contrasted to other microorganisms.
TextSentencer_T163 30658-30792 Sentence denotes The results highlight an interesting link between public good specialisation and (a) private funding and (b) distribution to industry.
TextSentencer_T163 30658-30792 Sentence denotes The results highlight an interesting link between public good specialisation and (a) private funding and (b) distribution to industry.
TextSentencer_T163 30658-30792 Sentence denotes The results highlight an interesting link between public good specialisation and (a) private funding and (b) distribution to industry.
TextSentencer_T164 30793-31265 Sentence denotes The picture that emerges from the analysis in this paper of the heterogeneity amongst the culture collections is that differences in organisational -especially related to funding mechanisms -and contractual mechanisms -especially related to the conditions of transfer of materials -is beneficial for creating the kind of organisational diversity which is needed to sustain the culture collections' activities in various different micro-economic and institutional contexts.
TextSentencer_T164 30793-31265 Sentence denotes The picture that emerges from the analysis in this paper of the heterogeneity amongst the culture collections is that differences in organisational -especially related to funding mechanisms -and contractual mechanisms -especially related to the conditions of transfer of materials -is beneficial for creating the kind of organisational diversity which is needed to sustain the culture collections' activities in various different micro-economic and institutional contexts.
TextSentencer_T164 30793-31265 Sentence denotes The picture that emerges from the analysis in this paper of the heterogeneity amongst the culture collections is that differences in organisational -especially related to funding mechanisms -and contractual mechanisms -especially related to the conditions of transfer of materials -is beneficial for creating the kind of organisational diversity which is needed to sustain the culture collections' activities in various different micro-economic and institutional contexts.
TextSentencer_T165 31266-31436 Sentence denotes This in turn is necessary in order to address the challenge of creating sufficient storage space for the wealth of microbes being deposited in the PSMCs on a daily basis.
TextSentencer_T165 31266-31436 Sentence denotes This in turn is necessary in order to address the challenge of creating sufficient storage space for the wealth of microbes being deposited in the PSMCs on a daily basis.
TextSentencer_T165 31266-31436 Sentence denotes This in turn is necessary in order to address the challenge of creating sufficient storage space for the wealth of microbes being deposited in the PSMCs on a daily basis.
TextSentencer_T166 31437-31842 Sentence denotes In addition, the analysis shows that the heterogeneity allows accommodating the private sectors' specific interest in and support for the conservation and distribution of certain subsets of microbial resources, such as the microbial type strains analysed in this paper, in a manner that is compatible with the core mission of the PSMCs to guarantee the broad public availability of its microbial holdings.
TextSentencer_T166 31437-31842 Sentence denotes In addition, the analysis shows that the heterogeneity allows accommodating the private sectors' specific interest in and support for the conservation and distribution of certain subsets of microbial resources, such as the microbial type strains analysed in this paper, in a manner that is compatible with the core mission of the PSMCs to guarantee the broad public availability of its microbial holdings.
TextSentencer_T166 31437-31842 Sentence denotes In addition, the analysis shows that the heterogeneity allows accommodating the private sectors' specific interest in and support for the conservation and distribution of certain subsets of microbial resources, such as the microbial type strains analysed in this paper, in a manner that is compatible with the core mission of the PSMCs to guarantee the broad public availability of its microbial holdings.
TextSentencer_T167 31843-32321 Sentence denotes Last but not least, it is important to distinguish between the different underlying incentives of collections, and from this understanding to guarantee the kind of conservation strategies needed to support different services such as providing insurance for solving future biological threats as well as to offer solutions to current problems, such as waste water treatment and catalysing ethanol production as a sustainable energy source (Canovas and Iborra, 2003) to name a few.
TextSentencer_T167 31843-32321 Sentence denotes Last but not least, it is important to distinguish between the different underlying incentives of collections, and from this understanding to guarantee the kind of conservation strategies needed to support different services such as providing insurance for solving future biological threats as well as to offer solutions to current problems, such as waste water treatment and catalysing ethanol production as a sustainable energy source (Canovas and Iborra, 2003) to name a few.
TextSentencer_T167 31843-32321 Sentence denotes Last but not least, it is important to distinguish between the different underlying incentives of collections, and from this understanding to guarantee the kind of conservation strategies needed to support different services such as providing insurance for solving future biological threats as well as to offer solutions to current problems, such as waste water treatment and catalysing ethanol production as a sustainable energy source (Canovas and Iborra, 2003) to name a few.
TextSentencer_T168 32322-32506 Sentence denotes In this sense, policy makers need to ensure that the ex situ collections' conservation strategies balance the current needs of applied research and the requirements for basic research.
TextSentencer_T168 32322-32506 Sentence denotes In this sense, policy makers need to ensure that the ex situ collections' conservation strategies balance the current needs of applied research and the requirements for basic research.
TextSentencer_T168 32322-32506 Sentence denotes In this sense, policy makers need to ensure that the ex situ collections' conservation strategies balance the current needs of applied research and the requirements for basic research.