CORD-19-Sentences  

CORD-19:b8ff0ebca4694d95758a53d05e58ac177778c7f4 JSONTXT 11 Projects

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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-81 Sentence denotes Identification of New Pathogens in the Intraocular Fluid of Patients With Uveitis
TextSentencer_T1 0-81 Sentence denotes Identification of New Pathogens in the Intraocular Fluid of Patients With Uveitis
TextSentencer_T1 0-81 Sentence denotes Identification of New Pathogens in the Intraocular Fluid of Patients With Uveitis
TextSentencer_T2 83-91 Sentence denotes Abstract
TextSentencer_T2 83-91 Sentence denotes Abstract
TextSentencer_T2 83-91 Sentence denotes Abstract
TextSentencer_T3 94-104 Sentence denotes • PURPOSE:
TextSentencer_T3 94-104 Sentence denotes • PURPOSE:
TextSentencer_T3 94-104 Sentence denotes • PURPOSE:
TextSentencer_T4 105-210 Sentence denotes To determine infectious causes in patients with uveitis of unknown origin by intraocular fluids analysis.
TextSentencer_T4 105-210 Sentence denotes To determine infectious causes in patients with uveitis of unknown origin by intraocular fluids analysis.
TextSentencer_T4 105-210 Sentence denotes To determine infectious causes in patients with uveitis of unknown origin by intraocular fluids analysis.
TextSentencer_T5 211-220 Sentence denotes • DESIGN:
TextSentencer_T5 211-220 Sentence denotes • DESIGN:
TextSentencer_T5 211-220 Sentence denotes • DESIGN:
TextSentencer_T6 221-248 Sentence denotes Case-control study. origin.
TextSentencer_T6 221-248 Sentence denotes Case-control study. origin.
TextSentencer_T6 221-248 Sentence denotes Case-control study. origin.
TextSentencer_T7 249-379 Sentence denotes Infections are thought to cause approximately 20% to 25% of cases; about 30% are associated with a noninfectious systemic disease.
TextSentencer_T7 249-379 Sentence denotes Infections are thought to cause approximately 20% to 25% of cases; about 30% are associated with a noninfectious systemic disease.
TextSentencer_T7 249-379 Sentence denotes Infections are thought to cause approximately 20% to 25% of cases; about 30% are associated with a noninfectious systemic disease.
TextSentencer_T8 380-561 Sentence denotes Although for patient management and the efficacy of treatment, the differential diagnosis is crucial, in more than half of the uveitis patients the underlying cause remains unknown.
TextSentencer_T8 380-561 Sentence denotes Although for patient management and the efficacy of treatment, the differential diagnosis is crucial, in more than half of the uveitis patients the underlying cause remains unknown.
TextSentencer_T8 380-561 Sentence denotes Although for patient management and the efficacy of treatment, the differential diagnosis is crucial, in more than half of the uveitis patients the underlying cause remains unknown.
TextSentencer_T9 562-737 Sentence denotes The pathogens most commonly associated with infectious uveitis in immunocompetent patients are Toxoplasma gondii, herpes simplex virus (HSV), and varicella-zoster virus (VZV).
TextSentencer_T9 562-737 Sentence denotes The pathogens most commonly associated with infectious uveitis in immunocompetent patients are Toxoplasma gondii, herpes simplex virus (HSV), and varicella-zoster virus (VZV).
TextSentencer_T9 562-737 Sentence denotes The pathogens most commonly associated with infectious uveitis in immunocompetent patients are Toxoplasma gondii, herpes simplex virus (HSV), and varicella-zoster virus (VZV).
TextSentencer_T10 738-1010 Sentence denotes In recent years, a few other infectious agents have been implicated in the etiology of uveitis, most notably rubella virus and cytomegalovirus (CMV). [1] [2] [3] [4] [5] [6] [7] CMV is currently recognized as the most common cause of uveitis in immunocompromised patients.
TextSentencer_T10 738-1010 Sentence denotes In recent years, a few other infectious agents have been implicated in the etiology of uveitis, most notably rubella virus and cytomegalovirus (CMV). [1] [2] [3] [4] [5] [6] [7] CMV is currently recognized as the most common cause of uveitis in immunocompromised patients.
TextSentencer_T10 738-1010 Sentence denotes In recent years, a few other infectious agents have been implicated in the etiology of uveitis, most notably rubella virus and cytomegalovirus (CMV). [1] [2] [3] [4] [5] [6] [7] CMV is currently recognized as the most common cause of uveitis in immunocompromised patients.
TextSentencer_T11 1011-1133 Sentence denotes In this study we performed an extensive search for infectious agents that cause uveitis but so far have escaped attention.
TextSentencer_T11 1011-1133 Sentence denotes In this study we performed an extensive search for infectious agents that cause uveitis but so far have escaped attention.
TextSentencer_T11 1011-1133 Sentence denotes In this study we performed an extensive search for infectious agents that cause uveitis but so far have escaped attention.
TextSentencer_T12 1134-1330 Sentence denotes Aqueous humor samples from 139 uveitis patients were analyzed retrospectively in our laboratory by available real-time polymerase chain reaction (PCR) assays for a variety of viruses and bacteria.
TextSentencer_T12 1134-1330 Sentence denotes Aqueous humor samples from 139 uveitis patients were analyzed retrospectively in our laboratory by available real-time polymerase chain reaction (PCR) assays for a variety of viruses and bacteria.
TextSentencer_T12 1134-1330 Sentence denotes Aqueous humor samples from 139 uveitis patients were analyzed retrospectively in our laboratory by available real-time polymerase chain reaction (PCR) assays for a variety of viruses and bacteria.
TextSentencer_T13 1331-1890 Sentence denotes Included were pathogens previously associated with uveitis (enteroviruses, Epstein-Barr viruses [EBV] , human herpesvirus 6 [HHV6], influenza virus, rubella virus, Mycoplasma pneumoniae) and those causing conjunctivitis and/or keratitis or encephalitis (adenoviruses, coronaviruses, enteroviruses, influenza virus, parainfluenzaviruses, human parechovirus [HPeV], respiratory syncytial virus, Chlamydia pneumoniae, Chlamydia trachomatis) 1,5,8 -30 Our findings suggest that human parechovirus may be involved in the pathogenesis of infectious (kerato)uveitis.
TextSentencer_T13 1331-1890 Sentence denotes Included were pathogens previously associated with uveitis (enteroviruses, Epstein-Barr viruses [EBV] , human herpesvirus 6 [HHV6], influenza virus, rubella virus, Mycoplasma pneumoniae) and those causing conjunctivitis and/or keratitis or encephalitis (adenoviruses, coronaviruses, enteroviruses, influenza virus, parainfluenzaviruses, human parechovirus [HPeV], respiratory syncytial virus, Chlamydia pneumoniae, Chlamydia trachomatis) 1,5,8 -30 Our findings suggest that human parechovirus may be involved in the pathogenesis of infectious (kerato)uveitis.
TextSentencer_T13 1331-1890 Sentence denotes Included were pathogens previously associated with uveitis (enteroviruses, Epstein-Barr viruses [EBV] , human herpesvirus 6 [HHV6], influenza virus, rubella virus, Mycoplasma pneumoniae) and those causing conjunctivitis and/or keratitis or encephalitis (adenoviruses, coronaviruses, enteroviruses, influenza virus, parainfluenzaviruses, human parechovirus [HPeV], respiratory syncytial virus, Chlamydia pneumoniae, Chlamydia trachomatis) 1,5,8 -30 Our findings suggest that human parechovirus may be involved in the pathogenesis of infectious (kerato)uveitis.
TextSentencer_T14 1891-1914 Sentence denotes • PATIENTS AND SAMPLES:
TextSentencer_T14 1891-1914 Sentence denotes • PATIENTS AND SAMPLES:
TextSentencer_T14 1891-1914 Sentence denotes • PATIENTS AND SAMPLES:
TextSentencer_T15 1915-2150 Sentence denotes Ocular fluid samples analyzed in this study were from 629 uveitis patients who visited the ophthalmology clinic of the University Medical Center Utrecht from October 1, 2001 until June 30, 2006 and were suspected of infectious uveitis.
TextSentencer_T15 1915-2150 Sentence denotes Ocular fluid samples analyzed in this study were from 629 uveitis patients who visited the ophthalmology clinic of the University Medical Center Utrecht from October 1, 2001 until June 30, 2006 and were suspected of infectious uveitis.
TextSentencer_T15 1915-2150 Sentence denotes Ocular fluid samples analyzed in this study were from 629 uveitis patients who visited the ophthalmology clinic of the University Medical Center Utrecht from October 1, 2001 until June 30, 2006 and were suspected of infectious uveitis.
TextSentencer_T16 2151-2310 Sentence denotes The patients were classified using the uveitis nomenclature according to the recommendations of the Standardization of Uveitis Nomenclature working group 2005.
TextSentencer_T16 2151-2310 Sentence denotes The patients were classified using the uveitis nomenclature according to the recommendations of the Standardization of Uveitis Nomenclature working group 2005.
TextSentencer_T16 2151-2310 Sentence denotes The patients were classified using the uveitis nomenclature according to the recommendations of the Standardization of Uveitis Nomenclature working group 2005.
TextSentencer_T17 2311-2554 Sentence denotes 31 All patients had undergone the uveitis screening consisting of erythrocyte sedimentation rate, red and white blood cell counts, determination of serum angiotensinconverting enzyme levels, serologic tests for syphilis, and chest radiography.
TextSentencer_T17 2311-2554 Sentence denotes 31 All patients had undergone the uveitis screening consisting of erythrocyte sedimentation rate, red and white blood cell counts, determination of serum angiotensinconverting enzyme levels, serologic tests for syphilis, and chest radiography.
TextSentencer_T17 2311-2554 Sentence denotes 31 All patients had undergone the uveitis screening consisting of erythrocyte sedimentation rate, red and white blood cell counts, determination of serum angiotensinconverting enzyme levels, serologic tests for syphilis, and chest radiography.
TextSentencer_T18 2555-2631 Sentence denotes Selected patients also underwent serologic testing for Borrelia burgdorferi.
TextSentencer_T18 2555-2631 Sentence denotes Selected patients also underwent serologic testing for Borrelia burgdorferi.
TextSentencer_T18 2555-2631 Sentence denotes Selected patients also underwent serologic testing for Borrelia burgdorferi.
TextSentencer_T19 2632-2708 Sentence denotes For all 629 patients aqueous sampling was performed for diagnostic purposes.
TextSentencer_T19 2632-2708 Sentence denotes For all 629 patients aqueous sampling was performed for diagnostic purposes.
TextSentencer_T19 2632-2708 Sentence denotes For all 629 patients aqueous sampling was performed for diagnostic purposes.
TextSentencer_T20 2709-2813 Sentence denotes The samples were stored at Ϫ80°C within 5 hours of collection before processing for laboratory analysis.
TextSentencer_T20 2709-2813 Sentence denotes The samples were stored at Ϫ80°C within 5 hours of collection before processing for laboratory analysis.
TextSentencer_T20 2709-2813 Sentence denotes The samples were stored at Ϫ80°C within 5 hours of collection before processing for laboratory analysis.
TextSentencer_T21 2814-3019 Sentence denotes Initial analysis was performed for HSV, VZV, and in the case of posterior uveitis also for Toxoplasma and CMV, by PCR and by Goldmann-Witmer coefficient (GWC), to determine intraocular antibody production.
TextSentencer_T21 2814-3019 Sentence denotes Initial analysis was performed for HSV, VZV, and in the case of posterior uveitis also for Toxoplasma and CMV, by PCR and by Goldmann-Witmer coefficient (GWC), to determine intraocular antibody production.
TextSentencer_T21 2814-3019 Sentence denotes Initial analysis was performed for HSV, VZV, and in the case of posterior uveitis also for Toxoplasma and CMV, by PCR and by Goldmann-Witmer coefficient (GWC), to determine intraocular antibody production.
TextSentencer_T22 3020-3090 Sentence denotes Of the 629 patients, 486 were negative for the above mentioned agents.
TextSentencer_T22 3020-3090 Sentence denotes Of the 629 patients, 486 were negative for the above mentioned agents.
TextSentencer_T22 3020-3090 Sentence denotes Of the 629 patients, 486 were negative for the above mentioned agents.
TextSentencer_T23 3091-3173 Sentence denotes A sufficient amount of ocular fluid remained for this study in 139 of these cases.
TextSentencer_T23 3091-3173 Sentence denotes A sufficient amount of ocular fluid remained for this study in 139 of these cases.
TextSentencer_T23 3091-3173 Sentence denotes A sufficient amount of ocular fluid remained for this study in 139 of these cases.
TextSentencer_T24 3174-3279 Sentence denotes Forty-nine patients had anterior uveitis (AU) and 90 had posterior uveitis (PU) or panuveitis (Table 1) .
TextSentencer_T24 3174-3279 Sentence denotes Forty-nine patients had anterior uveitis (AU) and 90 had posterior uveitis (PU) or panuveitis (Table 1) .
TextSentencer_T24 3174-3279 Sentence denotes Forty-nine patients had anterior uveitis (AU) and 90 had posterior uveitis (PU) or panuveitis (Table 1) .
TextSentencer_T25 3280-3490 Sentence denotes Of the 49 AU patients, 2 were immunocompromised as a result of immunosuppressive medications (1 for lethal midline granuloma and the other after allogeneic stem cell transplantation for hematologic malignancy).
TextSentencer_T25 3280-3490 Sentence denotes Of the 49 AU patients, 2 were immunocompromised as a result of immunosuppressive medications (1 for lethal midline granuloma and the other after allogeneic stem cell transplantation for hematologic malignancy).
TextSentencer_T25 3280-3490 Sentence denotes Of the 49 AU patients, 2 were immunocompromised as a result of immunosuppressive medications (1 for lethal midline granuloma and the other after allogeneic stem cell transplantation for hematologic malignancy).
TextSentencer_T26 3491-3668 Sentence denotes Of the 90 patients with PU and panuveitis, 8 were immunocompromised, 5 of whom had acquired immunodeficiency syndrome and 3 of whom received immunosuppressive drugs ( Table 1) .
TextSentencer_T26 3491-3668 Sentence denotes Of the 90 patients with PU and panuveitis, 8 were immunocompromised, 5 of whom had acquired immunodeficiency syndrome and 3 of whom received immunosuppressive drugs ( Table 1) .
TextSentencer_T26 3491-3668 Sentence denotes Of the 90 patients with PU and panuveitis, 8 were immunocompromised, 5 of whom had acquired immunodeficiency syndrome and 3 of whom received immunosuppressive drugs ( Table 1) .
TextSentencer_T27 3669-4013 Sentence denotes The remainders of ocular fluid samples from patients with PCR-and/or GWC-confirmed infectious uveitis (ocular toxoplasmosis, n ϭ 13; HSV anterior uveitis, n ϭ 10; rubella virus-associated Fuchs heterochromic uveitis syndrome (FHUS), n ϭ 14) and from patients with cataract in the absence of intraocular inflammation (n ϭ 11) served as controls.
TextSentencer_T27 3669-4013 Sentence denotes The remainders of ocular fluid samples from patients with PCR-and/or GWC-confirmed infectious uveitis (ocular toxoplasmosis, n ϭ 13; HSV anterior uveitis, n ϭ 10; rubella virus-associated Fuchs heterochromic uveitis syndrome (FHUS), n ϭ 14) and from patients with cataract in the absence of intraocular inflammation (n ϭ 11) served as controls.
TextSentencer_T27 3669-4013 Sentence denotes The remainders of ocular fluid samples from patients with PCR-and/or GWC-confirmed infectious uveitis (ocular toxoplasmosis, n ϭ 13; HSV anterior uveitis, n ϭ 10; rubella virus-associated Fuchs heterochromic uveitis syndrome (FHUS), n ϭ 14) and from patients with cataract in the absence of intraocular inflammation (n ϭ 11) served as controls.
TextSentencer_T28 4014-4057 Sentence denotes • NUCLEIC ACID ISOLATION AND REAL-TIME PCR:
TextSentencer_T28 4014-4057 Sentence denotes • NUCLEIC ACID ISOLATION AND REAL-TIME PCR:
TextSentencer_T28 4014-4057 Sentence denotes • NUCLEIC ACID ISOLATION AND REAL-TIME PCR:
TextSentencer_T29 4058-4414 Sentence denotes The ocular fluid samples were analyzed for the presence of adenovirus, EBV, HHV6, Mycoplasma pneumoniae, Chlamydia pneumoniae, and Chlamydia trachomatis DNA and of coronaviruses 229E, OC43, and NL63, enteroviruses, human metapneumovirus, influenza A and B virus, parainfluenza virus 1 to 4, HPeV, respiratory syncytial virus A and B, and rubella virus RNA.
TextSentencer_T29 4058-4414 Sentence denotes The ocular fluid samples were analyzed for the presence of adenovirus, EBV, HHV6, Mycoplasma pneumoniae, Chlamydia pneumoniae, and Chlamydia trachomatis DNA and of coronaviruses 229E, OC43, and NL63, enteroviruses, human metapneumovirus, influenza A and B virus, parainfluenza virus 1 to 4, HPeV, respiratory syncytial virus A and B, and rubella virus RNA.
TextSentencer_T29 4058-4414 Sentence denotes The ocular fluid samples were analyzed for the presence of adenovirus, EBV, HHV6, Mycoplasma pneumoniae, Chlamydia pneumoniae, and Chlamydia trachomatis DNA and of coronaviruses 229E, OC43, and NL63, enteroviruses, human metapneumovirus, influenza A and B virus, parainfluenza virus 1 to 4, HPeV, respiratory syncytial virus A and B, and rubella virus RNA.
TextSentencer_T30 4415-4525 Sentence denotes If not done previously, samples from patients with anterior uveitis were also analyzed for CMV and Toxoplasma.
TextSentencer_T30 4415-4525 Sentence denotes If not done previously, samples from patients with anterior uveitis were also analyzed for CMV and Toxoplasma.
TextSentencer_T30 4415-4525 Sentence denotes If not done previously, samples from patients with anterior uveitis were also analyzed for CMV and Toxoplasma.
TextSentencer_T31 4526-4663 Sentence denotes DNA and RNA were extracted from 30 L of ocular fluid using the MagNa Pure LC Total Nucleic Acid isolation kit (Roche, Mannheim, Germany).
TextSentencer_T31 4526-4663 Sentence denotes DNA and RNA were extracted from 30 L of ocular fluid using the MagNa Pure LC Total Nucleic Acid isolation kit (Roche, Mannheim, Germany).
TextSentencer_T31 4526-4663 Sentence denotes DNA and RNA were extracted from 30 L of ocular fluid using the MagNa Pure LC Total Nucleic Acid isolation kit (Roche, Mannheim, Germany).
TextSentencer_T32 4664-4958 Sentence denotes To monitor the quality of the extraction and the subsequent amplification procedure, a standard dose of phocine herpesvirus type 1 and encephalomyocarditis virus was added to each sample as an internal control prior to extraction. [32] [33] [34] Nucleic acid was collected in a volume of 240 L.
TextSentencer_T32 4664-4958 Sentence denotes To monitor the quality of the extraction and the subsequent amplification procedure, a standard dose of phocine herpesvirus type 1 and encephalomyocarditis virus was added to each sample as an internal control prior to extraction. [32] [33] [34] Nucleic acid was collected in a volume of 240 L.
TextSentencer_T32 4664-4958 Sentence denotes To monitor the quality of the extraction and the subsequent amplification procedure, a standard dose of phocine herpesvirus type 1 and encephalomyocarditis virus was added to each sample as an internal control prior to extraction. [32] [33] [34] Nucleic acid was collected in a volume of 240 L.
TextSentencer_T33 4959-5261 Sentence denotes For detection of RNA viruses, copyDNA (cDNA) was produced by mixing 40 L of extracted nucleic acid with 60 L of reverse transcriptase mix (Taqman, reverse transcription reagents; Applied Biosystems, Foster City, California, USA) and incubating the mixture for 10 minutes at 25°C and 30 minutes at 48°C.
TextSentencer_T33 4959-5261 Sentence denotes For detection of RNA viruses, copyDNA (cDNA) was produced by mixing 40 L of extracted nucleic acid with 60 L of reverse transcriptase mix (Taqman, reverse transcription reagents; Applied Biosystems, Foster City, California, USA) and incubating the mixture for 10 minutes at 25°C and 30 minutes at 48°C.
TextSentencer_T33 4959-5261 Sentence denotes For detection of RNA viruses, copyDNA (cDNA) was produced by mixing 40 L of extracted nucleic acid with 60 L of reverse transcriptase mix (Taqman, reverse transcription reagents; Applied Biosystems, Foster City, California, USA) and incubating the mixture for 10 minutes at 25°C and 30 minutes at 48°C.
TextSentencer_T34 5262-5338 Sentence denotes The cDNA synthesis reaction was stopped by incubating for 5 minutes at 95°C.
TextSentencer_T34 5262-5338 Sentence denotes The cDNA synthesis reaction was stopped by incubating for 5 minutes at 95°C.
TextSentencer_T34 5262-5338 Sentence denotes The cDNA synthesis reaction was stopped by incubating for 5 minutes at 95°C.
TextSentencer_T35 5339-5462 Sentence denotes Per amplification reaction 10 L of extracted nucleic acid (for DNA detection) or 10 L of cDNA (for RNA detection) was used.
TextSentencer_T35 5339-5462 Sentence denotes Per amplification reaction 10 L of extracted nucleic acid (for DNA detection) or 10 L of cDNA (for RNA detection) was used.
TextSentencer_T35 5339-5462 Sentence denotes Per amplification reaction 10 L of extracted nucleic acid (for DNA detection) or 10 L of cDNA (for RNA detection) was used.
TextSentencer_T36 5463-5596 Sentence denotes Real-time PCR assays were performed on an ABI Prism 7700 sequence detection system (Applied Biosystems, Branchburg, New Jersey, USA).
TextSentencer_T36 5463-5596 Sentence denotes Real-time PCR assays were performed on an ABI Prism 7700 sequence detection system (Applied Biosystems, Branchburg, New Jersey, USA).
TextSentencer_T36 5463-5596 Sentence denotes Real-time PCR assays were performed on an ABI Prism 7700 sequence detection system (Applied Biosystems, Branchburg, New Jersey, USA).
TextSentencer_T37 5597-5787 Sentence denotes For Chlamydia trachomatis, 25 L of extracted nucleic acid was analyzed using the Cobas Amplicor Chlamydia trachomatis detection kit according to the instructions of the manufacturer (Roche).
TextSentencer_T37 5597-5787 Sentence denotes For Chlamydia trachomatis, 25 L of extracted nucleic acid was analyzed using the Cobas Amplicor Chlamydia trachomatis detection kit according to the instructions of the manufacturer (Roche).
TextSentencer_T37 5597-5787 Sentence denotes For Chlamydia trachomatis, 25 L of extracted nucleic acid was analyzed using the Cobas Amplicor Chlamydia trachomatis detection kit according to the instructions of the manufacturer (Roche).
TextSentencer_T38 5788-5819 Sentence denotes All samples were examined once.
TextSentencer_T38 5788-5819 Sentence denotes All samples were examined once.
TextSentencer_T38 5788-5819 Sentence denotes All samples were examined once.
TextSentencer_T39 5820-5889 Sentence denotes In case of positive outcomes the real-time PCR reaction was repeated.
TextSentencer_T39 5820-5889 Sentence denotes In case of positive outcomes the real-time PCR reaction was repeated.
TextSentencer_T39 5820-5889 Sentence denotes In case of positive outcomes the real-time PCR reaction was repeated.
TextSentencer_T40 5890-5972 Sentence denotes Two human parechovirus-positive samples were confirmed by nucleic acid sequencing.
TextSentencer_T40 5890-5972 Sentence denotes Two human parechovirus-positive samples were confirmed by nucleic acid sequencing.
TextSentencer_T40 5890-5972 Sentence denotes Two human parechovirus-positive samples were confirmed by nucleic acid sequencing.
TextSentencer_T41 5973-6040 Sentence denotes Samples for which the internal control was inhibited were excluded.
TextSentencer_T41 5973-6040 Sentence denotes Samples for which the internal control was inhibited were excluded.
TextSentencer_T41 5973-6040 Sentence denotes Samples for which the internal control was inhibited were excluded.
TextSentencer_T42 6041-6092 Sentence denotes The primers and probes used are listed in Table 2 .
TextSentencer_T42 6041-6092 Sentence denotes The primers and probes used are listed in Table 2 .
TextSentencer_T42 6041-6092 Sentence denotes The primers and probes used are listed in Table 2 .
TextSentencer_T43 6093-6121 Sentence denotes • ANTIBODY DETECTION ASSAYS:
TextSentencer_T43 6093-6121 Sentence denotes • ANTIBODY DETECTION ASSAYS:
TextSentencer_T43 6093-6121 Sentence denotes • ANTIBODY DETECTION ASSAYS:
TextSentencer_T44 6122-6246 Sentence denotes Intraocular production of antibody against rubella virus (Goldmann-Witmer coefficient) was assessed as described previously.
TextSentencer_T44 6122-6246 Sentence denotes Intraocular production of antibody against rubella virus (Goldmann-Witmer coefficient) was assessed as described previously.
TextSentencer_T44 6122-6246 Sentence denotes Intraocular production of antibody against rubella virus (Goldmann-Witmer coefficient) was assessed as described previously.
TextSentencer_T45 6247-6428 Sentence denotes 1 Serum and intraocular immunoglobulin (Ig)G titers against HHV6 were determined using the Biotrin International Human Herpes Virus 6 IgG immunofluorescence assay (Dublin, Ireland).
TextSentencer_T45 6247-6428 Sentence denotes 1 Serum and intraocular immunoglobulin (Ig)G titers against HHV6 were determined using the Biotrin International Human Herpes Virus 6 IgG immunofluorescence assay (Dublin, Ireland).
TextSentencer_T45 6247-6428 Sentence denotes 1 Serum and intraocular immunoglobulin (Ig)G titers against HHV6 were determined using the Biotrin International Human Herpes Virus 6 IgG immunofluorescence assay (Dublin, Ireland).
TextSentencer_T46 6429-6532 Sentence denotes Serum and intraocular IgG against EBV was determined using the Panbio VCA IgG ELISA (Grenoble, France).
TextSentencer_T46 6429-6532 Sentence denotes Serum and intraocular IgG against EBV was determined using the Panbio VCA IgG ELISA (Grenoble, France).
TextSentencer_T46 6429-6532 Sentence denotes Serum and intraocular IgG against EBV was determined using the Panbio VCA IgG ELISA (Grenoble, France).
TextSentencer_T47 6534-6548 Sentence denotes was inhibited.
TextSentencer_T47 6534-6548 Sentence denotes was inhibited.
TextSentencer_T47 6534-6548 Sentence denotes was inhibited.
TextSentencer_T48 6549-6721 Sentence denotes In the patient samples positive PCR reactions were found for Epstein-Barr virus (n ϭ 1), rubella virus (n ϭ 1), human herpesvirus 6 (n ϭ 1), and human parechovirus (n ϭ 4).
TextSentencer_T48 6549-6721 Sentence denotes In the patient samples positive PCR reactions were found for Epstein-Barr virus (n ϭ 1), rubella virus (n ϭ 1), human herpesvirus 6 (n ϭ 1), and human parechovirus (n ϭ 4).
TextSentencer_T48 6549-6721 Sentence denotes In the patient samples positive PCR reactions were found for Epstein-Barr virus (n ϭ 1), rubella virus (n ϭ 1), human herpesvirus 6 (n ϭ 1), and human parechovirus (n ϭ 4).
TextSentencer_T49 6722-6778 Sentence denotes The PCR reactions for all other pathogens were negative.
TextSentencer_T49 6722-6778 Sentence denotes The PCR reactions for all other pathogens were negative.
TextSentencer_T49 6722-6778 Sentence denotes The PCR reactions for all other pathogens were negative.
TextSentencer_T50 6779-7013 Sentence denotes All control samples were negative except for 3; 2 toxoplasma chorioretinitis control samples were positive for EBV and 1 sample positive for rubella virus intraocular antibody production also tested PCR-positive for rubella virus RNA.
TextSentencer_T50 6779-7013 Sentence denotes All control samples were negative except for 3; 2 toxoplasma chorioretinitis control samples were positive for EBV and 1 sample positive for rubella virus intraocular antibody production also tested PCR-positive for rubella virus RNA.
TextSentencer_T50 6779-7013 Sentence denotes All control samples were negative except for 3; 2 toxoplasma chorioretinitis control samples were positive for EBV and 1 sample positive for rubella virus intraocular antibody production also tested PCR-positive for rubella virus RNA.
TextSentencer_T51 7014-7151 Sentence denotes The patients with uveitis of unknown cause and a positive PCR result for rubella virus, HHV6, and human parechovirus are described below.
TextSentencer_T51 7014-7151 Sentence denotes The patients with uveitis of unknown cause and a positive PCR result for rubella virus, HHV6, and human parechovirus are described below.
TextSentencer_T51 7014-7151 Sentence denotes The patients with uveitis of unknown cause and a positive PCR result for rubella virus, HHV6, and human parechovirus are described below.
TextSentencer_T52 7152-7177 Sentence denotes • RUBELLA VIRUS (CASE 1):
TextSentencer_T52 7152-7177 Sentence denotes • RUBELLA VIRUS (CASE 1):
TextSentencer_T52 7152-7177 Sentence denotes • RUBELLA VIRUS (CASE 1):
TextSentencer_T53 7178-7277 Sentence denotes A 40-year-old female patient complained of gradual decrease of visual acuity in the right eye (OD).
TextSentencer_T53 7178-7277 Sentence denotes A 40-year-old female patient complained of gradual decrease of visual acuity in the right eye (OD).
TextSentencer_T53 7178-7277 Sentence denotes A 40-year-old female patient complained of gradual decrease of visual acuity in the right eye (OD).
TextSentencer_T54 7278-7402 Sentence denotes Her medical history included pneumotho-rax and bilateral pneumonia many years ago, but she had no signs of systemic disease.
TextSentencer_T54 7278-7402 Sentence denotes Her medical history included pneumotho-rax and bilateral pneumonia many years ago, but she had no signs of systemic disease.
TextSentencer_T54 7278-7402 Sentence denotes Her medical history included pneumotho-rax and bilateral pneumonia many years ago, but she had no signs of systemic disease.
TextSentencer_T55 7403-7441 Sentence denotes The visual acuity of the OD was 20/80.
TextSentencer_T55 7403-7441 Sentence denotes The visual acuity of the OD was 20/80.
TextSentencer_T55 7403-7441 Sentence denotes The visual acuity of the OD was 20/80.
TextSentencer_T56 7442-7519 Sentence denotes The anterior chamber and vitreous of the OD revealed cells, but no synechiae.
TextSentencer_T56 7442-7519 Sentence denotes The anterior chamber and vitreous of the OD revealed cells, but no synechiae.
TextSentencer_T56 7442-7519 Sentence denotes The anterior chamber and vitreous of the OD revealed cells, but no synechiae.
TextSentencer_T57 7520-7619 Sentence denotes There was a subcapsular posterior cataract, fine keratic precipitates (KPs) and vitreous opacities.
TextSentencer_T57 7520-7619 Sentence denotes There was a subcapsular posterior cataract, fine keratic precipitates (KPs) and vitreous opacities.
TextSentencer_T57 7520-7619 Sentence denotes There was a subcapsular posterior cataract, fine keratic precipitates (KPs) and vitreous opacities.
TextSentencer_T58 7620-7642 Sentence denotes The retina was normal.
TextSentencer_T58 7620-7642 Sentence denotes The retina was normal.
TextSentencer_T58 7620-7642 Sentence denotes The retina was normal.
TextSentencer_T59 7643-7720 Sentence denotes The left eye (OS) had full visual acuity and no abnormalities on examination.
TextSentencer_T59 7643-7720 Sentence denotes The left eye (OS) had full visual acuity and no abnormalities on examination.
TextSentencer_T59 7643-7720 Sentence denotes The left eye (OS) had full visual acuity and no abnormalities on examination.
TextSentencer_T60 7721-7773 Sentence denotes Uveitis screening results were within normal limits.
TextSentencer_T60 7721-7773 Sentence denotes Uveitis screening results were within normal limits.
TextSentencer_T60 7721-7773 Sentence denotes Uveitis screening results were within normal limits.
TextSentencer_T61 7774-7983 Sentence denotes The clinical diagnosis of Fuchs heterochromic uveitis syndrome was made and a cataract extraction with implantation of an intraocular lens was performed as well as pars plana vitrectomy for vitreous opacities.
TextSentencer_T61 7774-7983 Sentence denotes The clinical diagnosis of Fuchs heterochromic uveitis syndrome was made and a cataract extraction with implantation of an intraocular lens was performed as well as pars plana vitrectomy for vitreous opacities.
TextSentencer_T61 7774-7983 Sentence denotes The clinical diagnosis of Fuchs heterochromic uveitis syndrome was made and a cataract extraction with implantation of an intraocular lens was performed as well as pars plana vitrectomy for vitreous opacities.
TextSentencer_T62 7984-8175 Sentence denotes On examination of the vitreous, there was no evidence for systemic and/or intraocular infection using PCR and GWC for CMV, HSV, VZV, Toxoplasma, Borrelia burgdorferi, and Bartonella henselae.
TextSentencer_T62 7984-8175 Sentence denotes On examination of the vitreous, there was no evidence for systemic and/or intraocular infection using PCR and GWC for CMV, HSV, VZV, Toxoplasma, Borrelia burgdorferi, and Bartonella henselae.
TextSentencer_T62 7984-8175 Sentence denotes On examination of the vitreous, there was no evidence for systemic and/or intraocular infection using PCR and GWC for CMV, HSV, VZV, Toxoplasma, Borrelia burgdorferi, and Bartonella henselae.
TextSentencer_T63 8176-8269 Sentence denotes Microbiological cultures were negative and cytologic examination revealed no malignant cells.
TextSentencer_T63 8176-8269 Sentence denotes Microbiological cultures were negative and cytologic examination revealed no malignant cells.
TextSentencer_T63 8176-8269 Sentence denotes Microbiological cultures were negative and cytologic examination revealed no malignant cells.
TextSentencer_T64 8270-8327 Sentence denotes By PCR, rubella virus was detected in the vitreous fluid.
TextSentencer_T64 8270-8327 Sentence denotes By PCR, rubella virus was detected in the vitreous fluid.
TextSentencer_T64 8270-8327 Sentence denotes By PCR, rubella virus was detected in the vitreous fluid.
TextSentencer_T65 8328-8455 Sentence denotes Subsequent antibody analysis for rubella virus revealed the presence of intraocular IgG, but the GWC was negative (ratio 2.02).
TextSentencer_T65 8328-8455 Sentence denotes Subsequent antibody analysis for rubella virus revealed the presence of intraocular IgG, but the GWC was negative (ratio 2.02).
TextSentencer_T65 8328-8455 Sentence denotes Subsequent antibody analysis for rubella virus revealed the presence of intraocular IgG, but the GWC was negative (ratio 2.02).
TextSentencer_T66 8456-8580 Sentence denotes However, in comparison with HSV, VZV, CMV en Toxoplasma, intraocular antibody production against rubella virus was elevated.
TextSentencer_T66 8456-8580 Sentence denotes However, in comparison with HSV, VZV, CMV en Toxoplasma, intraocular antibody production against rubella virus was elevated.
TextSentencer_T66 8456-8580 Sentence denotes However, in comparison with HSV, VZV, CMV en Toxoplasma, intraocular antibody production against rubella virus was elevated.
TextSentencer_T67 8581-8612 Sentence denotes • HUMAN HERPESVIRUS-6 (CASE 2):
TextSentencer_T67 8581-8612 Sentence denotes • HUMAN HERPESVIRUS-6 (CASE 2):
TextSentencer_T67 8581-8612 Sentence denotes • HUMAN HERPESVIRUS-6 (CASE 2):
TextSentencer_T68 8613-8725 Sentence denotes A 42-year-old man was referred because of decrease in visual acuity of his OD and floaters since 3 months prior.
TextSentencer_T68 8613-8725 Sentence denotes A 42-year-old man was referred because of decrease in visual acuity of his OD and floaters since 3 months prior.
TextSentencer_T68 8613-8725 Sentence denotes A 42-year-old man was referred because of decrease in visual acuity of his OD and floaters since 3 months prior.
TextSentencer_T69 8726-8803 Sentence denotes His medical history was not contributory and the patient used no medications.
TextSentencer_T69 8726-8803 Sentence denotes His medical history was not contributory and the patient used no medications.
TextSentencer_T69 8726-8803 Sentence denotes His medical history was not contributory and the patient used no medications.
TextSentencer_T70 8804-8855 Sentence denotes Uveitis screening results were within normal range.
TextSentencer_T70 8804-8855 Sentence denotes Uveitis screening results were within normal range.
TextSentencer_T70 8804-8855 Sentence denotes Uveitis screening results were within normal range.
TextSentencer_T71 8856-8926 Sentence denotes Remarkable was the heterochromia of his eyes, present since childhood.
TextSentencer_T71 8856-8926 Sentence denotes Remarkable was the heterochromia of his eyes, present since childhood.
TextSentencer_T71 8856-8926 Sentence denotes Remarkable was the heterochromia of his eyes, present since childhood.
TextSentencer_T72 8927-9037 Sentence denotes There was no serologic evidence for an active infection with CMV, HSV, VZV, Toxoplasma, or Treponema pallidum.
TextSentencer_T72 8927-9037 Sentence denotes There was no serologic evidence for an active infection with CMV, HSV, VZV, Toxoplasma, or Treponema pallidum.
TextSentencer_T72 8927-9037 Sentence denotes There was no serologic evidence for an active infection with CMV, HSV, VZV, Toxoplasma, or Treponema pallidum.
TextSentencer_T73 9038-9180 Sentence denotes Borrelia burgdorferi serum IgG and immunoblot were positive; however, a distinction between a past and an ongoing infection could not be made.
TextSentencer_T73 9038-9180 Sentence denotes Borrelia burgdorferi serum IgG and immunoblot were positive; however, a distinction between a past and an ongoing infection could not be made.
TextSentencer_T73 9038-9180 Sentence denotes Borrelia burgdorferi serum IgG and immunoblot were positive; however, a distinction between a past and an ongoing infection could not be made.
TextSentencer_T74 9181-9336 Sentence denotes On ocular examination, the visual acuity of the OD was 20/25; the cornea revealed the presence of keratic precipitates, but the anterior chamber was clear.
TextSentencer_T74 9181-9336 Sentence denotes On ocular examination, the visual acuity of the OD was 20/25; the cornea revealed the presence of keratic precipitates, but the anterior chamber was clear.
TextSentencer_T74 9181-9336 Sentence denotes On ocular examination, the visual acuity of the OD was 20/25; the cornea revealed the presence of keratic precipitates, but the anterior chamber was clear.
TextSentencer_T75 9337-9434 Sentence denotes There were no synechiae, but several small noduli were present on the pupillary edge of the iris.
TextSentencer_T75 9337-9434 Sentence denotes There were no synechiae, but several small noduli were present on the pupillary edge of the iris.
TextSentencer_T75 9337-9434 Sentence denotes There were no synechiae, but several small noduli were present on the pupillary edge of the iris.
TextSentencer_T76 9435-9461 Sentence denotes Cataract was not observed.
TextSentencer_T76 9435-9461 Sentence denotes Cataract was not observed.
TextSentencer_T76 9435-9461 Sentence denotes Cataract was not observed.
TextSentencer_T77 9462-9540 Sentence denotes Funduscopy of the OD revealed vitreous cells and several peripheral snowballs.
TextSentencer_T77 9462-9540 Sentence denotes Funduscopy of the OD revealed vitreous cells and several peripheral snowballs.
TextSentencer_T77 9462-9540 Sentence denotes Funduscopy of the OD revealed vitreous cells and several peripheral snowballs.
TextSentencer_T78 9541-9578 Sentence denotes The fundoscopic findings were normal.
TextSentencer_T78 9541-9578 Sentence denotes The fundoscopic findings were normal.
TextSentencer_T78 9541-9578 Sentence denotes The fundoscopic findings were normal.
TextSentencer_T79 9579-9668 Sentence denotes The OS had full visual acuity; however, some peripheral vitreous opacities were observed.
TextSentencer_T79 9579-9668 Sentence denotes The OS had full visual acuity; however, some peripheral vitreous opacities were observed.
TextSentencer_T79 9579-9668 Sentence denotes The OS had full visual acuity; however, some peripheral vitreous opacities were observed.
TextSentencer_T80 9669-9844 Sentence denotes Because of the possible (previous) infection with Borrelia, the patient was treated with intravenous ceftriaxone and additionally with periocular steroids, but with no effect.
TextSentencer_T80 9669-9844 Sentence denotes Because of the possible (previous) infection with Borrelia, the patient was treated with intravenous ceftriaxone and additionally with periocular steroids, but with no effect.
TextSentencer_T80 9669-9844 Sentence denotes Because of the possible (previous) infection with Borrelia, the patient was treated with intravenous ceftriaxone and additionally with periocular steroids, but with no effect.
TextSentencer_T81 9845-9966 Sentence denotes Diagnostic vitrectomy was performed and cytologic and microbiological examinations did not reveal a cause of his uveitis.
TextSentencer_T81 9845-9966 Sentence denotes Diagnostic vitrectomy was performed and cytologic and microbiological examinations did not reveal a cause of his uveitis.
TextSentencer_T81 9845-9966 Sentence denotes Diagnostic vitrectomy was performed and cytologic and microbiological examinations did not reveal a cause of his uveitis.
TextSentencer_T82 9967-10054 Sentence denotes Vitreous analysis was negative for CMV, HSV, VZV, and Borrelia, both by PCR and by GWC.
TextSentencer_T82 9967-10054 Sentence denotes Vitreous analysis was negative for CMV, HSV, VZV, and Borrelia, both by PCR and by GWC.
TextSentencer_T82 9967-10054 Sentence denotes Vitreous analysis was negative for CMV, HSV, VZV, and Borrelia, both by PCR and by GWC.
TextSentencer_T83 10055-10202 Sentence denotes The rubella virus GWC was negative (ratio 2.68), although intraocular IgG was detected and the GWC was elevated in comparison to CMV, HSV, and VZV.
TextSentencer_T83 10055-10202 Sentence denotes The rubella virus GWC was negative (ratio 2.68), although intraocular IgG was detected and the GWC was elevated in comparison to CMV, HSV, and VZV.
TextSentencer_T83 10055-10202 Sentence denotes The rubella virus GWC was negative (ratio 2.68), although intraocular IgG was detected and the GWC was elevated in comparison to CMV, HSV, and VZV.
TextSentencer_T84 10203-10265 Sentence denotes Therefore, rubella virusassociated FHUS could not be excluded.
TextSentencer_T84 10203-10265 Sentence denotes Therefore, rubella virusassociated FHUS could not be excluded.
TextSentencer_T84 10203-10265 Sentence denotes Therefore, rubella virusassociated FHUS could not be excluded.
TextSentencer_T85 10266-10390 Sentence denotes Three months after vitrectomy the patient regained full visual acuity, although the keratic precipitates in his OD remained.
TextSentencer_T85 10266-10390 Sentence denotes Three months after vitrectomy the patient regained full visual acuity, although the keratic precipitates in his OD remained.
TextSentencer_T85 10266-10390 Sentence denotes Three months after vitrectomy the patient regained full visual acuity, although the keratic precipitates in his OD remained.
TextSentencer_T86 10391-10467 Sentence denotes Retrospectively, the vitreous fluid appeared to be positive for HHV6 by PCR.
TextSentencer_T86 10391-10467 Sentence denotes Retrospectively, the vitreous fluid appeared to be positive for HHV6 by PCR.
TextSentencer_T86 10391-10467 Sentence denotes Retrospectively, the vitreous fluid appeared to be positive for HHV6 by PCR.
TextSentencer_T87 10468-10549 Sentence denotes Immunofluorescence assay demonstrated that the patient was seropositive for HHV6.
TextSentencer_T87 10468-10549 Sentence denotes Immunofluorescence assay demonstrated that the patient was seropositive for HHV6.
TextSentencer_T87 10468-10549 Sentence denotes Immunofluorescence assay demonstrated that the patient was seropositive for HHV6.
TextSentencer_T88 10550-10578 Sentence denotes • HUMAN PARECHOVIRUS:CASE 3.
TextSentencer_T88 10550-10578 Sentence denotes • HUMAN PARECHOVIRUS:CASE 3.
TextSentencer_T88 10550-10578 Sentence denotes • HUMAN PARECHOVIRUS:CASE 3.
TextSentencer_T89 10579-10699 Sentence denotes A 54-year-old male patient was referred to our center with anterior uveitis of 2 years' duration in his pseudophakic OS.
TextSentencer_T89 10579-10699 Sentence denotes A 54-year-old male patient was referred to our center with anterior uveitis of 2 years' duration in his pseudophakic OS.
TextSentencer_T89 10579-10699 Sentence denotes A 54-year-old male patient was referred to our center with anterior uveitis of 2 years' duration in his pseudophakic OS.
TextSentencer_T90 10700-10842 Sentence denotes Twenty-nine years prior, the patient underwent cataract extraction and implantation of an iris-clip lens in his OS because of previous trauma.
TextSentencer_T90 10700-10842 Sentence denotes Twenty-nine years prior, the patient underwent cataract extraction and implantation of an iris-clip lens in his OS because of previous trauma.
TextSentencer_T90 10700-10842 Sentence denotes Twenty-nine years prior, the patient underwent cataract extraction and implantation of an iris-clip lens in his OS because of previous trauma.
TextSentencer_T91 10843-10924 Sentence denotes On ocular examination, the visual acuity of the OS was hand movements (Table 3) .
TextSentencer_T91 10843-10924 Sentence denotes On ocular examination, the visual acuity of the OS was hand movements (Table 3) .
TextSentencer_T91 10843-10924 Sentence denotes On ocular examination, the visual acuity of the OS was hand movements (Table 3) .
TextSentencer_T92 10925-11029 Sentence denotes A central corneal scar was seen, cells were present in the anterior chamber, and the vitreous was clear.
TextSentencer_T92 10925-11029 Sentence denotes A central corneal scar was seen, cells were present in the anterior chamber, and the vitreous was clear.
TextSentencer_T92 10925-11029 Sentence denotes A central corneal scar was seen, cells were present in the anterior chamber, and the vitreous was clear.
TextSentencer_T93 11030-11067 Sentence denotes Funduscopy revealed no abnormalities.
TextSentencer_T93 11030-11067 Sentence denotes Funduscopy revealed no abnormalities.
TextSentencer_T93 11030-11067 Sentence denotes Funduscopy revealed no abnormalities.
TextSentencer_T94 11068-11119 Sentence denotes The OD had full visual acuity and no abnormalities.
TextSentencer_T94 11068-11119 Sentence denotes The OD had full visual acuity and no abnormalities.
TextSentencer_T94 11068-11119 Sentence denotes The OD had full visual acuity and no abnormalities.
TextSentencer_T95 11120-11162 Sentence denotes Both eyes had normal intraocular pressure.
TextSentencer_T95 11120-11162 Sentence denotes Both eyes had normal intraocular pressure.
TextSentencer_T95 11120-11162 Sentence denotes Both eyes had normal intraocular pressure.
TextSentencer_T96 11163-11226 Sentence denotes The patient had no systemic complaints and used no medications.
TextSentencer_T96 11163-11226 Sentence denotes The patient had no systemic complaints and used no medications.
TextSentencer_T96 11163-11226 Sentence denotes The patient had no systemic complaints and used no medications.
TextSentencer_T97 11227-11279 Sentence denotes Uveitis screening results were within normal limits.
TextSentencer_T97 11227-11279 Sentence denotes Uveitis screening results were within normal limits.
TextSentencer_T97 11227-11279 Sentence denotes Uveitis screening results were within normal limits.
TextSentencer_T98 11280-11331 Sentence denotes This patient was also diagnosed with neurosyphilis.
TextSentencer_T98 11280-11331 Sentence denotes This patient was also diagnosed with neurosyphilis.
TextSentencer_T98 11280-11331 Sentence denotes This patient was also diagnosed with neurosyphilis.
TextSentencer_T99 11332-11449 Sentence denotes Uveitis was clinically attributed to irritation caused by the iris-clip lens, which was therefore surgically removed.
TextSentencer_T99 11332-11449 Sentence denotes Uveitis was clinically attributed to irritation caused by the iris-clip lens, which was therefore surgically removed.
TextSentencer_T99 11332-11449 Sentence denotes Uveitis was clinically attributed to irritation caused by the iris-clip lens, which was therefore surgically removed.
TextSentencer_T100 11450-11496 Sentence denotes A vitreous sample was obtained during surgery.
TextSentencer_T100 11450-11496 Sentence denotes A vitreous sample was obtained during surgery.
TextSentencer_T100 11450-11496 Sentence denotes A vitreous sample was obtained during surgery.
TextSentencer_T101 11497-11675 Sentence denotes Analysis of the ocular fluid was negative for HSV and VZV, both by PCR and GWC, and for CMV and Toxoplasma by PCR, but was retrospectively positive for human parechovirus by PCR.
TextSentencer_T101 11497-11675 Sentence denotes Analysis of the ocular fluid was negative for HSV and VZV, both by PCR and GWC, and for CMV and Toxoplasma by PCR, but was retrospectively positive for human parechovirus by PCR.
TextSentencer_T101 11497-11675 Sentence denotes Analysis of the ocular fluid was negative for HSV and VZV, both by PCR and GWC, and for CMV and Toxoplasma by PCR, but was retrospectively positive for human parechovirus by PCR.
TextSentencer_T102 11676-11762 Sentence denotes Ocular examination 4 months after removal of the intraocular lens revealed a quiet OS.
TextSentencer_T102 11676-11762 Sentence denotes Ocular examination 4 months after removal of the intraocular lens revealed a quiet OS.
TextSentencer_T102 11676-11762 Sentence denotes Ocular examination 4 months after removal of the intraocular lens revealed a quiet OS.
TextSentencer_T103 11763-11770 Sentence denotes Case 4.
TextSentencer_T103 11763-11770 Sentence denotes Case 4.
TextSentencer_T103 11763-11770 Sentence denotes Case 4.
TextSentencer_T104 11771-11845 Sentence denotes A 53-year-old male was referred because of persistent keratitis of his OS.
TextSentencer_T104 11771-11845 Sentence denotes A 53-year-old male was referred because of persistent keratitis of his OS.
TextSentencer_T104 11771-11845 Sentence denotes A 53-year-old male was referred because of persistent keratitis of his OS.
TextSentencer_T105 11846-11981 Sentence denotes It was thought to be caused by HSV, but the patient did not respond to systemic and topical treatments with acyclovir and valacyclovir.
TextSentencer_T105 11846-11981 Sentence denotes It was thought to be caused by HSV, but the patient did not respond to systemic and topical treatments with acyclovir and valacyclovir.
TextSentencer_T105 11846-11981 Sentence denotes It was thought to be caused by HSV, but the patient did not respond to systemic and topical treatments with acyclovir and valacyclovir.
TextSentencer_T106 11982-12046 Sentence denotes His previous medical and ophthalmic histories were unremarkable.
TextSentencer_T106 11982-12046 Sentence denotes His previous medical and ophthalmic histories were unremarkable.
TextSentencer_T106 11982-12046 Sentence denotes His previous medical and ophthalmic histories were unremarkable.
TextSentencer_T107 12047-12098 Sentence denotes Uveitis screening did not reveal any abnormalities.
TextSentencer_T107 12047-12098 Sentence denotes Uveitis screening did not reveal any abnormalities.
TextSentencer_T107 12047-12098 Sentence denotes Uveitis screening did not reveal any abnormalities.
TextSentencer_T108 12099-12161 Sentence denotes On ocular examination, the visual acuity of the OS was 20/100.
TextSentencer_T108 12099-12161 Sentence denotes On ocular examination, the visual acuity of the OS was 20/100.
TextSentencer_T108 12099-12161 Sentence denotes On ocular examination, the visual acuity of the OS was 20/100.
TextSentencer_T109 12162-12299 Sentence denotes An infiltrate in the upper part of the cornea with epithelial defect and sporadic cells in the anterior chamber were observed (Table 3) .
TextSentencer_T109 12162-12299 Sentence denotes An infiltrate in the upper part of the cornea with epithelial defect and sporadic cells in the anterior chamber were observed (Table 3) .
TextSentencer_T109 12162-12299 Sentence denotes An infiltrate in the upper part of the cornea with epithelial defect and sporadic cells in the anterior chamber were observed (Table 3) .
TextSentencer_T110 12300-12331 Sentence denotes Corneal sensitivity was normal.
TextSentencer_T110 12300-12331 Sentence denotes Corneal sensitivity was normal.
TextSentencer_T110 12300-12331 Sentence denotes Corneal sensitivity was normal.
TextSentencer_T111 12332-12398 Sentence denotes The vitreous was clear and the retinal findings were unremarkable.
TextSentencer_T111 12332-12398 Sentence denotes The vitreous was clear and the retinal findings were unremarkable.
TextSentencer_T111 12332-12398 Sentence denotes The vitreous was clear and the retinal findings were unremarkable.
TextSentencer_T112 12399-12431 Sentence denotes Intraocular pressure was normal.
TextSentencer_T112 12399-12431 Sentence denotes Intraocular pressure was normal.
TextSentencer_T112 12399-12431 Sentence denotes Intraocular pressure was normal.
TextSentencer_T113 12432-12483 Sentence denotes The OD had full visual acuity and no abnormalities.
TextSentencer_T113 12432-12483 Sentence denotes The OD had full visual acuity and no abnormalities.
TextSentencer_T113 12432-12483 Sentence denotes The OD had full visual acuity and no abnormalities.
TextSentencer_T114 12484-12648 Sentence denotes Aqueous analysis was negative for HSV, VZV, and Toxoplasma by both PCR and GWC and for CMV by PCR; however, retrospectively PCR was positive for human parechovirus.
TextSentencer_T114 12484-12648 Sentence denotes Aqueous analysis was negative for HSV, VZV, and Toxoplasma by both PCR and GWC and for CMV by PCR; however, retrospectively PCR was positive for human parechovirus.
TextSentencer_T114 12484-12648 Sentence denotes Aqueous analysis was negative for HSV, VZV, and Toxoplasma by both PCR and GWC and for CMV by PCR; however, retrospectively PCR was positive for human parechovirus.
TextSentencer_T115 12649-12766 Sentence denotes The patient was treated with antibiotic eye ointment and the corneal lesion and anterior uveitis slowly became quiet.
TextSentencer_T115 12649-12766 Sentence denotes The patient was treated with antibiotic eye ointment and the corneal lesion and anterior uveitis slowly became quiet.
TextSentencer_T115 12649-12766 Sentence denotes The patient was treated with antibiotic eye ointment and the corneal lesion and anterior uveitis slowly became quiet.
TextSentencer_T116 12767-12952 Sentence denotes A 73-year-old female patient with an ophthalmologic history of cataract extraction in both eyes at the age of 70 was referred to our institution because of secondary glaucoma in the OD.
TextSentencer_T116 12767-12952 Sentence denotes A 73-year-old female patient with an ophthalmologic history of cataract extraction in both eyes at the age of 70 was referred to our institution because of secondary glaucoma in the OD.
TextSentencer_T116 12767-12952 Sentence denotes A 73-year-old female patient with an ophthalmologic history of cataract extraction in both eyes at the age of 70 was referred to our institution because of secondary glaucoma in the OD.
TextSentencer_T117 12953-13016 Sentence denotes The patient had no systemic complaints and used no medications.
TextSentencer_T117 12953-13016 Sentence denotes The patient had no systemic complaints and used no medications.
TextSentencer_T117 12953-13016 Sentence denotes The patient had no systemic complaints and used no medications.
TextSentencer_T118 13017-13100 Sentence denotes The OD revealed pupillary seclusion with an intraocular pressure (IOP) of 50 mm Hg.
TextSentencer_T118 13017-13100 Sentence denotes The OD revealed pupillary seclusion with an intraocular pressure (IOP) of 50 mm Hg.
TextSentencer_T118 13017-13100 Sentence denotes The OD revealed pupillary seclusion with an intraocular pressure (IOP) of 50 mm Hg.
TextSentencer_T119 13101-13188 Sentence denotes On examination corneal edema and keratic precipitates were noted in the OD ( Table 3 ).
TextSentencer_T119 13101-13188 Sentence denotes On examination corneal edema and keratic precipitates were noted in the OD ( Table 3 ).
TextSentencer_T119 13101-13188 Sentence denotes On examination corneal edema and keratic precipitates were noted in the OD ( Table 3 ).
TextSentencer_T120 13189-13222 Sentence denotes The iris revealed atrophic areas.
TextSentencer_T120 13189-13222 Sentence denotes The iris revealed atrophic areas.
TextSentencer_T120 13189-13222 Sentence denotes The iris revealed atrophic areas.
TextSentencer_T121 13223-13318 Sentence denotes Fluorescein angiography revealed slight optic disc leakage and cystoid macular edema in the OD.
TextSentencer_T121 13223-13318 Sentence denotes Fluorescein angiography revealed slight optic disc leakage and cystoid macular edema in the OD.
TextSentencer_T121 13223-13318 Sentence denotes Fluorescein angiography revealed slight optic disc leakage and cystoid macular edema in the OD.
TextSentencer_T122 13319-13514 Sentence denotes The IOP initially normalized with laser iridotomy and local treatment; however, intermittent periods with IOP elevations up to 50 mm Hg were regularly encountered and trabeculectomy was required.
TextSentencer_T122 13319-13514 Sentence denotes The IOP initially normalized with laser iridotomy and local treatment; however, intermittent periods with IOP elevations up to 50 mm Hg were regularly encountered and trabeculectomy was required.
TextSentencer_T122 13319-13514 Sentence denotes The IOP initially normalized with laser iridotomy and local treatment; however, intermittent periods with IOP elevations up to 50 mm Hg were regularly encountered and trabeculectomy was required.
TextSentencer_T123 13515-13651 Sentence denotes The presumed diagnosis included low-grade Propionibacterium endophthalmitis and other various causes of hypertensive uveitis (Table 3) .
TextSentencer_T123 13515-13651 Sentence denotes The presumed diagnosis included low-grade Propionibacterium endophthalmitis and other various causes of hypertensive uveitis (Table 3) .
TextSentencer_T123 13515-13651 Sentence denotes The presumed diagnosis included low-grade Propionibacterium endophthalmitis and other various causes of hypertensive uveitis (Table 3) .
TextSentencer_T124 13652-13749 Sentence denotes Screening examinations were within normal limits as well as serology for Borrelia and Bartonella.
TextSentencer_T124 13652-13749 Sentence denotes Screening examinations were within normal limits as well as serology for Borrelia and Bartonella.
TextSentencer_T124 13652-13749 Sentence denotes Screening examinations were within normal limits as well as serology for Borrelia and Bartonella.
TextSentencer_T125 13750-13873 Sentence denotes Aqueous sampling was performed and PCR was negative for HSV, VZV, CMV, and Toxoplasma and GWC was negative for HSV and VZV.
TextSentencer_T125 13750-13873 Sentence denotes Aqueous sampling was performed and PCR was negative for HSV, VZV, CMV, and Toxoplasma and GWC was negative for HSV and VZV.
TextSentencer_T125 13750-13873 Sentence denotes Aqueous sampling was performed and PCR was negative for HSV, VZV, CMV, and Toxoplasma and GWC was negative for HSV and VZV.
TextSentencer_T126 13874-13919 Sentence denotes Cultures were negative for Propionibacterium.
TextSentencer_T126 13874-13919 Sentence denotes Cultures were negative for Propionibacterium.
TextSentencer_T126 13874-13919 Sentence denotes Cultures were negative for Propionibacterium.
TextSentencer_T127 13920-13998 Sentence denotes Retrospectively, the patient was found positive for human parechovirus by PCR.
TextSentencer_T127 13920-13998 Sentence denotes Retrospectively, the patient was found positive for human parechovirus by PCR.
TextSentencer_T127 13920-13998 Sentence denotes Retrospectively, the patient was found positive for human parechovirus by PCR.
TextSentencer_T128 13999-14006 Sentence denotes Case 6.
TextSentencer_T128 13999-14006 Sentence denotes Case 6.
TextSentencer_T128 13999-14006 Sentence denotes Case 6.
TextSentencer_T129 14007-14136 Sentence denotes A 37-year-old male patient was referred because of panuveitis with a focal chorioretinitis lesion in his OS since 3 months prior.
TextSentencer_T129 14007-14136 Sentence denotes A 37-year-old male patient was referred because of panuveitis with a focal chorioretinitis lesion in his OS since 3 months prior.
TextSentencer_T129 14007-14136 Sentence denotes A 37-year-old male patient was referred because of panuveitis with a focal chorioretinitis lesion in his OS since 3 months prior.
TextSentencer_T130 14137-14203 Sentence denotes At that time visual acuity in his OS decreased to finger counting.
TextSentencer_T130 14137-14203 Sentence denotes At that time visual acuity in his OS decreased to finger counting.
TextSentencer_T130 14137-14203 Sentence denotes At that time visual acuity in his OS decreased to finger counting.
TextSentencer_T131 14204-14555 Sentence denotes On examination KPs and cells in the anterior chamber and vitreous were noted with an active lesion located in the periphery of the retina (Table 3) EBV, the causative agent of infectious mononucleosis and several malignancies, has been implicated as a possible cause of uveitis and in primary ocular non-Hodgkin lymphoma of the central nervous system.
TextSentencer_T131 14204-14555 Sentence denotes On examination KPs and cells in the anterior chamber and vitreous were noted with an active lesion located in the periphery of the retina (Table 3) EBV, the causative agent of infectious mononucleosis and several malignancies, has been implicated as a possible cause of uveitis and in primary ocular non-Hodgkin lymphoma of the central nervous system.
TextSentencer_T131 14204-14555 Sentence denotes On examination KPs and cells in the anterior chamber and vitreous were noted with an active lesion located in the periphery of the retina (Table 3) EBV, the causative agent of infectious mononucleosis and several malignancies, has been implicated as a possible cause of uveitis and in primary ocular non-Hodgkin lymphoma of the central nervous system.
TextSentencer_T132 14556-14719 Sentence denotes 16, 26, 35 In our study EBV was detected in the ocular fluid of 1 patient with anterior uveitis of unknown cause and in 2 patients with toxoplasma chorioretinitis.
TextSentencer_T132 14556-14719 Sentence denotes 16, 26, 35 In our study EBV was detected in the ocular fluid of 1 patient with anterior uveitis of unknown cause and in 2 patients with toxoplasma chorioretinitis.
TextSentencer_T132 14556-14719 Sentence denotes 16, 26, 35 In our study EBV was detected in the ocular fluid of 1 patient with anterior uveitis of unknown cause and in 2 patients with toxoplasma chorioretinitis.
TextSentencer_T133 14720-14826 Sentence denotes IgG analysis in these 3 patients did not show any evidence of intraocular antibody production against EBV.
TextSentencer_T133 14720-14826 Sentence denotes IgG analysis in these 3 patients did not show any evidence of intraocular antibody production against EBV.
TextSentencer_T133 14720-14826 Sentence denotes IgG analysis in these 3 patients did not show any evidence of intraocular antibody production against EBV.
TextSentencer_T134 14827-14989 Sentence denotes The presence of EBV genome in the eyes of patients with various causes of uveitis was demonstrated previously and was found independent of the clinical diagnosis.
TextSentencer_T134 14827-14989 Sentence denotes The presence of EBV genome in the eyes of patients with various causes of uveitis was demonstrated previously and was found independent of the clinical diagnosis.
TextSentencer_T134 14827-14989 Sentence denotes The presence of EBV genome in the eyes of patients with various causes of uveitis was demonstrated previously and was found independent of the clinical diagnosis.
TextSentencer_T135 14990-15064 Sentence denotes The clinical significance of this phenomenon has not yet been established.
TextSentencer_T135 14990-15064 Sentence denotes The clinical significance of this phenomenon has not yet been established.
TextSentencer_T135 14990-15064 Sentence denotes The clinical significance of this phenomenon has not yet been established.
TextSentencer_T136 15065-15277 Sentence denotes 18, 36, 37 Moreover, as in our study, Ongkosuwito and associates found EBV also in ocular fluids from patients with laboratory-confirmed toxoplasmosis and in ocular fluids of patients without ocular inflammation.
TextSentencer_T136 15065-15277 Sentence denotes 18, 36, 37 Moreover, as in our study, Ongkosuwito and associates found EBV also in ocular fluids from patients with laboratory-confirmed toxoplasmosis and in ocular fluids of patients without ocular inflammation.
TextSentencer_T136 15065-15277 Sentence denotes 18, 36, 37 Moreover, as in our study, Ongkosuwito and associates found EBV also in ocular fluids from patients with laboratory-confirmed toxoplasmosis and in ocular fluids of patients without ocular inflammation.
TextSentencer_T137 15278-15404 Sentence denotes 18 intraocular antibody production analysis are required to determine whether EBV is a true cause of intraocular inflammation.
TextSentencer_T137 15278-15404 Sentence denotes 18 intraocular antibody production analysis are required to determine whether EBV is a true cause of intraocular inflammation.
TextSentencer_T137 15278-15404 Sentence denotes 18 intraocular antibody production analysis are required to determine whether EBV is a true cause of intraocular inflammation.
TextSentencer_T138 15405-15523 Sentence denotes One patient was PCR-positive for rubella virus, the causative agent of German measles and congenital rubella syndrome.
TextSentencer_T138 15405-15523 Sentence denotes One patient was PCR-positive for rubella virus, the causative agent of German measles and congenital rubella syndrome.
TextSentencer_T138 15405-15523 Sentence denotes One patient was PCR-positive for rubella virus, the causative agent of German measles and congenital rubella syndrome.
TextSentencer_T139 15524-15593 Sentence denotes 38 Rubella virus has been associated with FHUS and FHUS-like uveitis.
TextSentencer_T139 15524-15593 Sentence denotes 38 Rubella virus has been associated with FHUS and FHUS-like uveitis.
TextSentencer_T139 15524-15593 Sentence denotes 38 Rubella virus has been associated with FHUS and FHUS-like uveitis.
TextSentencer_T140 15594-15717 Sentence denotes 1, 5, 39, 40 This patient was clinically diagnosed with incomplete FHUS, as she did not have iris heterochromia or atrophy.
TextSentencer_T140 15594-15717 Sentence denotes 1, 5, 39, 40 This patient was clinically diagnosed with incomplete FHUS, as she did not have iris heterochromia or atrophy.
TextSentencer_T140 15594-15717 Sentence denotes 1, 5, 39, 40 This patient was clinically diagnosed with incomplete FHUS, as she did not have iris heterochromia or atrophy.
TextSentencer_T141 15718-15833 Sentence denotes HHV6 is a beta-herpesvirus and the causative agent of roseola infantum (or exanthema subitum), a childhood disease.
TextSentencer_T141 15718-15833 Sentence denotes HHV6 is a beta-herpesvirus and the causative agent of roseola infantum (or exanthema subitum), a childhood disease.
TextSentencer_T141 15718-15833 Sentence denotes HHV6 is a beta-herpesvirus and the causative agent of roseola infantum (or exanthema subitum), a childhood disease.
TextSentencer_T142 15834-15970 Sentence denotes 41 In addition, HHV6 is being recognized as an important opportunistic infection following bone marrow and/or stem cell transplantation.
TextSentencer_T142 15834-15970 Sentence denotes 41 In addition, HHV6 is being recognized as an important opportunistic infection following bone marrow and/or stem cell transplantation.
TextSentencer_T142 15834-15970 Sentence denotes 41 In addition, HHV6 is being recognized as an important opportunistic infection following bone marrow and/or stem cell transplantation.
TextSentencer_T143 15971-16053 Sentence denotes 42 Our HHV6 PCRpositive patient (Case 2) was neither a child nor immunosuppressed.
TextSentencer_T143 15971-16053 Sentence denotes 42 Our HHV6 PCRpositive patient (Case 2) was neither a child nor immunosuppressed.
TextSentencer_T143 15971-16053 Sentence denotes 42 Our HHV6 PCRpositive patient (Case 2) was neither a child nor immunosuppressed.
TextSentencer_T144 16054-16180 Sentence denotes Antibody analysis of the ocular fluid by immunofluorescence assay did not reveal the presence of intraocular IgG against HHV6.
TextSentencer_T144 16054-16180 Sentence denotes Antibody analysis of the ocular fluid by immunofluorescence assay did not reveal the presence of intraocular IgG against HHV6.
TextSentencer_T144 16054-16180 Sentence denotes Antibody analysis of the ocular fluid by immunofluorescence assay did not reveal the presence of intraocular IgG against HHV6.
TextSentencer_T145 16181-16284 Sentence denotes However, absence of intraocular antibody production does not necessarily exclude intraocular infection.
TextSentencer_T145 16181-16284 Sentence denotes However, absence of intraocular antibody production does not necessarily exclude intraocular infection.
TextSentencer_T145 16181-16284 Sentence denotes However, absence of intraocular antibody production does not necessarily exclude intraocular infection.
TextSentencer_T146 16285-16432 Sentence denotes Previously, we reported that by simultaneous use of PCR and GWC in immunocompetent patients a diagnosis by PCR only was established in 9% of cases.
TextSentencer_T146 16285-16432 Sentence denotes Previously, we reported that by simultaneous use of PCR and GWC in immunocompetent patients a diagnosis by PCR only was established in 9% of cases.
TextSentencer_T146 16285-16432 Sentence denotes Previously, we reported that by simultaneous use of PCR and GWC in immunocompetent patients a diagnosis by PCR only was established in 9% of cases.
TextSentencer_T147 16433-16574 Sentence denotes 2 Moreover, de Boer and associates found that in patients with presumed herpetic anterior uveitis, PCR was more frequently positive than GWC.
TextSentencer_T147 16433-16574 Sentence denotes 2 Moreover, de Boer and associates found that in patients with presumed herpetic anterior uveitis, PCR was more frequently positive than GWC.
TextSentencer_T147 16433-16574 Sentence denotes 2 Moreover, de Boer and associates found that in patients with presumed herpetic anterior uveitis, PCR was more frequently positive than GWC.
TextSentencer_T148 16575-16688 Sentence denotes 43 HHV6 has been implicated in ocular inflammation, most notably when the posterior part of the eye was affected.
TextSentencer_T148 16575-16688 Sentence denotes 43 HHV6 has been implicated in ocular inflammation, most notably when the posterior part of the eye was affected.
TextSentencer_T148 16575-16688 Sentence denotes 43 HHV6 has been implicated in ocular inflammation, most notably when the posterior part of the eye was affected.
TextSentencer_T149 16689-16794 Sentence denotes 14, 15, 17, 19 Our patient had anterior uveitis with heterochromia that had been present since childhood.
TextSentencer_T149 16689-16794 Sentence denotes 14, 15, 17, 19 Our patient had anterior uveitis with heterochromia that had been present since childhood.
TextSentencer_T149 16689-16794 Sentence denotes 14, 15, 17, 19 Our patient had anterior uveitis with heterochromia that had been present since childhood.
TextSentencer_T150 16795-16906 Sentence denotes Heterochromia is classically associated with FHUS but can develop in other viral infections such as HSV or VZV.
TextSentencer_T150 16795-16906 Sentence denotes Heterochromia is classically associated with FHUS but can develop in other viral infections such as HSV or VZV.
TextSentencer_T150 16795-16906 Sentence denotes Heterochromia is classically associated with FHUS but can develop in other viral infections such as HSV or VZV.
TextSentencer_T151 16907-17186 Sentence denotes 44 The detection of HHV6 in the eye might not be a clinically relevant finding; however, like other (herpes)viruses, HHV6 can reside latently in cells of the lymphoid and myeloid lineage, and it may have entered the inflamed eye via immune cells, similar to HIV and possibly EBV.
TextSentencer_T151 16907-17186 Sentence denotes 44 The detection of HHV6 in the eye might not be a clinically relevant finding; however, like other (herpes)viruses, HHV6 can reside latently in cells of the lymphoid and myeloid lineage, and it may have entered the inflamed eye via immune cells, similar to HIV and possibly EBV.
TextSentencer_T151 16907-17186 Sentence denotes 44 The detection of HHV6 in the eye might not be a clinically relevant finding; however, like other (herpes)viruses, HHV6 can reside latently in cells of the lymphoid and myeloid lineage, and it may have entered the inflamed eye via immune cells, similar to HIV and possibly EBV.
TextSentencer_T152 17187-17302 Sentence denotes 6, 18, 19, 36, 45 The role of HHV6 as a cause of anterior uveitis is inconclusive and further studies are required.
TextSentencer_T152 17187-17302 Sentence denotes 6, 18, 19, 36, 45 The role of HHV6 as a cause of anterior uveitis is inconclusive and further studies are required.
TextSentencer_T152 17187-17302 Sentence denotes 6, 18, 19, 36, 45 The role of HHV6 as a cause of anterior uveitis is inconclusive and further studies are required.
TextSentencer_T153 17303-17393 Sentence denotes Human parechoviruses belong to the genus parechovirus within the family of Picornaviridae.
TextSentencer_T153 17303-17393 Sentence denotes Human parechoviruses belong to the genus parechovirus within the family of Picornaviridae.
TextSentencer_T153 17303-17393 Sentence denotes Human parechoviruses belong to the genus parechovirus within the family of Picornaviridae.
TextSentencer_T154 17394-17502 Sentence denotes They may cause gastroenteritis, encephalitis, and flaccid paralysis in young children, but rarely in adults.
TextSentencer_T154 17394-17502 Sentence denotes They may cause gastroenteritis, encephalitis, and flaccid paralysis in young children, but rarely in adults.
TextSentencer_T154 17394-17502 Sentence denotes They may cause gastroenteritis, encephalitis, and flaccid paralysis in young children, but rarely in adults.
TextSentencer_T155 17503-17760 Sentence denotes 29, 46 Ocular diseases attributable to other picornavirus infections, particularly enteroviruses such as echoviruses 11 and 19 and coxsackieviruses, have been published, but an association between parechoviruses and ocular disease has not been reported yet.
TextSentencer_T155 17503-17760 Sentence denotes 29, 46 Ocular diseases attributable to other picornavirus infections, particularly enteroviruses such as echoviruses 11 and 19 and coxsackieviruses, have been published, but an association between parechoviruses and ocular disease has not been reported yet.
TextSentencer_T155 17503-17760 Sentence denotes 29, 46 Ocular diseases attributable to other picornavirus infections, particularly enteroviruses such as echoviruses 11 and 19 and coxsackieviruses, have been published, but an association between parechoviruses and ocular disease has not been reported yet.
TextSentencer_T156 17761-17876 Sentence denotes 8 -12 In this study the ocular fluids of 4 patients with undiagnosed unilateral uveitis were PCR-positive for HPeV.
TextSentencer_T156 17761-17876 Sentence denotes 8 -12 In this study the ocular fluids of 4 patients with undiagnosed unilateral uveitis were PCR-positive for HPeV.
TextSentencer_T156 17761-17876 Sentence denotes 8 -12 In this study the ocular fluids of 4 patients with undiagnosed unilateral uveitis were PCR-positive for HPeV.
TextSentencer_T157 17877-18067 Sentence denotes Unfortunately, intraocular antibody production could not be established as appropriate serologic assays are not available and there was not enough ocular fluid left to perform viral culture.
TextSentencer_T157 17877-18067 Sentence denotes Unfortunately, intraocular antibody production could not be established as appropriate serologic assays are not available and there was not enough ocular fluid left to perform viral culture.
TextSentencer_T157 17877-18067 Sentence denotes Unfortunately, intraocular antibody production could not be established as appropriate serologic assays are not available and there was not enough ocular fluid left to perform viral culture.
TextSentencer_T158 18068-18144 Sentence denotes One patient (Case 6) with intraocular HPeV was immunocompromised (Table 3) .
TextSentencer_T158 18068-18144 Sentence denotes One patient (Case 6) with intraocular HPeV was immunocompromised (Table 3) .
TextSentencer_T158 18068-18144 Sentence denotes One patient (Case 6) with intraocular HPeV was immunocompromised (Table 3) .
TextSentencer_T159 18145-18256 Sentence denotes He had been diagnosed with active syphilis, but there were no indications for neurosyphilis or ocular syphilis.
TextSentencer_T159 18145-18256 Sentence denotes He had been diagnosed with active syphilis, but there were no indications for neurosyphilis or ocular syphilis.
TextSentencer_T159 18145-18256 Sentence denotes He had been diagnosed with active syphilis, but there were no indications for neurosyphilis or ocular syphilis.
TextSentencer_T160 18257-18327 Sentence denotes However, upon treatment with penicillin his ocular condition improved.
TextSentencer_T160 18257-18327 Sentence denotes However, upon treatment with penicillin his ocular condition improved.
TextSentencer_T160 18257-18327 Sentence denotes However, upon treatment with penicillin his ocular condition improved.
TextSentencer_T161 18328-18427 Sentence denotes As this patient was HIV-positive, multiple uveitis entities may have contributed to ocular disease.
TextSentencer_T161 18328-18427 Sentence denotes As this patient was HIV-positive, multiple uveitis entities may have contributed to ocular disease.
TextSentencer_T161 18328-18427 Sentence denotes As this patient was HIV-positive, multiple uveitis entities may have contributed to ocular disease.
TextSentencer_T162 18428-18598 Sentence denotes The other 3 patients all had unilateral anterior uveitis with corneal involvement and cells in the anterior chamber, which suggested an ocular viral infection (Table 3) .
TextSentencer_T162 18428-18598 Sentence denotes The other 3 patients all had unilateral anterior uveitis with corneal involvement and cells in the anterior chamber, which suggested an ocular viral infection (Table 3) .
TextSentencer_T162 18428-18598 Sentence denotes The other 3 patients all had unilateral anterior uveitis with corneal involvement and cells in the anterior chamber, which suggested an ocular viral infection (Table 3) .
TextSentencer_T163 18599-18715 Sentence denotes Further research is required to determine if HPeV plays a role in the pathogenesis of infectious (anterior) uveitis.
TextSentencer_T163 18599-18715 Sentence denotes Further research is required to determine if HPeV plays a role in the pathogenesis of infectious (anterior) uveitis.
TextSentencer_T163 18599-18715 Sentence denotes Further research is required to determine if HPeV plays a role in the pathogenesis of infectious (anterior) uveitis.
TextSentencer_T164 18716-18815 Sentence denotes It is surprising to find a virus that is associated with disease in children in the eyes of adults.
TextSentencer_T164 18716-18815 Sentence denotes It is surprising to find a virus that is associated with disease in children in the eyes of adults.
TextSentencer_T164 18716-18815 Sentence denotes It is surprising to find a virus that is associated with disease in children in the eyes of adults.
TextSentencer_T165 18816-18938 Sentence denotes However, other infections of childhood are known to cause intraocular disease in adults, as is the case for rubella virus.
TextSentencer_T165 18816-18938 Sentence denotes However, other infections of childhood are known to cause intraocular disease in adults, as is the case for rubella virus.
TextSentencer_T165 18816-18938 Sentence denotes However, other infections of childhood are known to cause intraocular disease in adults, as is the case for rubella virus.
TextSentencer_T166 18939-19070 Sentence denotes 1, 5, 39 The vast majority (132/139 [95%]) of ocular fluid samples were negative by PCR analysis for multiple viruses and bacteria.
TextSentencer_T166 18939-19070 Sentence denotes 1, 5, 39 The vast majority (132/139 [95%]) of ocular fluid samples were negative by PCR analysis for multiple viruses and bacteria.
TextSentencer_T166 18939-19070 Sentence denotes 1, 5, 39 The vast majority (132/139 [95%]) of ocular fluid samples were negative by PCR analysis for multiple viruses and bacteria.
TextSentencer_T167 19071-19118 Sentence denotes There are several explanations for this result.
TextSentencer_T167 19071-19118 Sentence denotes There are several explanations for this result.
TextSentencer_T167 19071-19118 Sentence denotes There are several explanations for this result.
TextSentencer_T168 19119-19171 Sentence denotes First, the uveitis might be of noninfectious origin.
TextSentencer_T168 19119-19171 Sentence denotes First, the uveitis might be of noninfectious origin.
TextSentencer_T168 19119-19171 Sentence denotes First, the uveitis might be of noninfectious origin.
TextSentencer_T169 19172-19282 Sentence denotes Second, the number of DNA or RNA copies present in the ocular samples may have been below the detection level.
TextSentencer_T169 19172-19282 Sentence denotes Second, the number of DNA or RNA copies present in the ocular samples may have been below the detection level.
TextSentencer_T169 19172-19282 Sentence denotes Second, the number of DNA or RNA copies present in the ocular samples may have been below the detection level.
TextSentencer_T170 19283-19411 Sentence denotes This may be attributable to the low amount of input nucleic acid, which is inherent to diagnostic assays with intraocular fluid.
TextSentencer_T170 19283-19411 Sentence denotes This may be attributable to the low amount of input nucleic acid, which is inherent to diagnostic assays with intraocular fluid.
TextSentencer_T170 19283-19411 Sentence denotes This may be attributable to the low amount of input nucleic acid, which is inherent to diagnostic assays with intraocular fluid.
TextSentencer_T171 19412-19530 Sentence denotes Alternatively, the time of sampling may have been such that the causative agent had already been cleared from the eye.
TextSentencer_T171 19412-19530 Sentence denotes Alternatively, the time of sampling may have been such that the causative agent had already been cleared from the eye.
TextSentencer_T171 19412-19530 Sentence denotes Alternatively, the time of sampling may have been such that the causative agent had already been cleared from the eye.
TextSentencer_T172 19531-19693 Sentence denotes In this case, other diagnostic approaches may be more useful, such as the detection of intraocular antibody production by Goldmann-Witmer coefficient calculation.
TextSentencer_T172 19531-19693 Sentence denotes In this case, other diagnostic approaches may be more useful, such as the detection of intraocular antibody production by Goldmann-Witmer coefficient calculation.
TextSentencer_T172 19531-19693 Sentence denotes In this case, other diagnostic approaches may be more useful, such as the detection of intraocular antibody production by Goldmann-Witmer coefficient calculation.
TextSentencer_T173 19694-19925 Sentence denotes It is known, also for systemic and neurologic viral infections, that a PCR assay is most sensitive early in infection, whereas antibody can be detected over a much longer period of time and thus provide a wider window of detection.
TextSentencer_T173 19694-19925 Sentence denotes It is known, also for systemic and neurologic viral infections, that a PCR assay is most sensitive early in infection, whereas antibody can be detected over a much longer period of time and thus provide a wider window of detection.
TextSentencer_T173 19694-19925 Sentence denotes It is known, also for systemic and neurologic viral infections, that a PCR assay is most sensitive early in infection, whereas antibody can be detected over a much longer period of time and thus provide a wider window of detection.
TextSentencer_T174 19926-20035 Sentence denotes 2, 43, 47, 48 Finally, it may be that other pathogens not covered by our assays were involved in these cases.
TextSentencer_T174 19926-20035 Sentence denotes 2, 43, 47, 48 Finally, it may be that other pathogens not covered by our assays were involved in these cases.
TextSentencer_T174 19926-20035 Sentence denotes 2, 43, 47, 48 Finally, it may be that other pathogens not covered by our assays were involved in these cases.
TextSentencer_T175 20036-20176 Sentence denotes Our study addressed multiple infectious causes in patients with undiagnosed uveitis and revealed a possible new cause of infectious uveitis.
TextSentencer_T175 20036-20176 Sentence denotes Our study addressed multiple infectious causes in patients with undiagnosed uveitis and revealed a possible new cause of infectious uveitis.
TextSentencer_T175 20036-20176 Sentence denotes Our study addressed multiple infectious causes in patients with undiagnosed uveitis and revealed a possible new cause of infectious uveitis.
TextSentencer_T176 20177-20287 Sentence denotes Further investigations are required to narrow the diagnostic gap in patients with presumed infectious uveitis.
TextSentencer_T176 20177-20287 Sentence denotes Further investigations are required to narrow the diagnostic gap in patients with presumed infectious uveitis.
TextSentencer_T176 20177-20287 Sentence denotes Further investigations are required to narrow the diagnostic gap in patients with presumed infectious uveitis.