CORD-19-Sentences  

CORD-19:53be4000821ac430bae87a7faf22ee1e493e5832 JSONTXT 12 Projects

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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-106 Sentence denotes Polyarteritis Nodosa in a Cat with Involvement of the Central and Peripheral Nervous Systems ScienceDirect
TextSentencer_T1 0-106 Sentence denotes Polyarteritis Nodosa in a Cat with Involvement of the Central and Peripheral Nervous Systems ScienceDirect
TextSentencer_T1 0-106 Sentence denotes Polyarteritis Nodosa in a Cat with Involvement of the Central and Peripheral Nervous Systems ScienceDirect
TextSentencer_T2 108-116 Sentence denotes Abstract
TextSentencer_T2 108-116 Sentence denotes Abstract
TextSentencer_T2 108-116 Sentence denotes Abstract
TextSentencer_T3 117-290 Sentence denotes An 18-month-old neutered male domestic shorthair cat was referred with a history of pyrexia, polyuria and polydypsia, and transient episodes of bilateral hindlimb paralysis.
TextSentencer_T3 117-290 Sentence denotes An 18-month-old neutered male domestic shorthair cat was referred with a history of pyrexia, polyuria and polydypsia, and transient episodes of bilateral hindlimb paralysis.
TextSentencer_T3 117-290 Sentence denotes An 18-month-old neutered male domestic shorthair cat was referred with a history of pyrexia, polyuria and polydypsia, and transient episodes of bilateral hindlimb paralysis.
TextSentencer_T4 291-404 Sentence denotes Cardiac evaluation revealed severe systemic hypertension and severe concentric hypertrophy of the left ventricle.
TextSentencer_T4 291-404 Sentence denotes Cardiac evaluation revealed severe systemic hypertension and severe concentric hypertrophy of the left ventricle.
TextSentencer_T4 291-404 Sentence denotes Cardiac evaluation revealed severe systemic hypertension and severe concentric hypertrophy of the left ventricle.
TextSentencer_T5 405-525 Sentence denotes One month later the cat had a new episode of hindlimb paralysis with recurrent seizures, and died in status epilepticus.
TextSentencer_T5 405-525 Sentence denotes One month later the cat had a new episode of hindlimb paralysis with recurrent seizures, and died in status epilepticus.
TextSentencer_T5 405-525 Sentence denotes One month later the cat had a new episode of hindlimb paralysis with recurrent seizures, and died in status epilepticus.
TextSentencer_T6 526-738 Sentence denotes At necropsy examination, the coronary arteries, arcuate renal arteries and common iliac arteries showed marked thickening with nodules segmentally located along the vessels and consequent narrowing of the lumina.
TextSentencer_T6 526-738 Sentence denotes At necropsy examination, the coronary arteries, arcuate renal arteries and common iliac arteries showed marked thickening with nodules segmentally located along the vessels and consequent narrowing of the lumina.
TextSentencer_T6 526-738 Sentence denotes At necropsy examination, the coronary arteries, arcuate renal arteries and common iliac arteries showed marked thickening with nodules segmentally located along the vessels and consequent narrowing of the lumina.
TextSentencer_T7 739-872 Sentence denotes Histologically, acute and chronic inflammatory infiltration of the vascular walls was associated with necrosis of the muscular layer.
TextSentencer_T7 739-872 Sentence denotes Histologically, acute and chronic inflammatory infiltration of the vascular walls was associated with necrosis of the muscular layer.
TextSentencer_T7 739-872 Sentence denotes Histologically, acute and chronic inflammatory infiltration of the vascular walls was associated with necrosis of the muscular layer.
TextSentencer_T8 873-1052 Sentence denotes Lesions were consistent with polyarteritis nodosa and involved the small, medium and large arteries of the heart, kidneys, small and large intestine, mesentery, liver and thyroid.
TextSentencer_T8 873-1052 Sentence denotes Lesions were consistent with polyarteritis nodosa and involved the small, medium and large arteries of the heart, kidneys, small and large intestine, mesentery, liver and thyroid.
TextSentencer_T8 873-1052 Sentence denotes Lesions were consistent with polyarteritis nodosa and involved the small, medium and large arteries of the heart, kidneys, small and large intestine, mesentery, liver and thyroid.
TextSentencer_T9 1053-1192 Sentence denotes Multifocal meningeal vasculitis associated with focal infarction of the frontal lobe and necrotizing vascular polyneuropathy were detected.
TextSentencer_T9 1053-1192 Sentence denotes Multifocal meningeal vasculitis associated with focal infarction of the frontal lobe and necrotizing vascular polyneuropathy were detected.
TextSentencer_T9 1053-1192 Sentence denotes Multifocal meningeal vasculitis associated with focal infarction of the frontal lobe and necrotizing vascular polyneuropathy were detected.
TextSentencer_T10 1193-1302 Sentence denotes Involvement of the central and peripheral nervous systems in polyarteritis nodosa is a novel finding in cats.
TextSentencer_T10 1193-1302 Sentence denotes Involvement of the central and peripheral nervous systems in polyarteritis nodosa is a novel finding in cats.
TextSentencer_T10 1193-1302 Sentence denotes Involvement of the central and peripheral nervous systems in polyarteritis nodosa is a novel finding in cats.
TextSentencer_T11 1304-1457 Sentence denotes Polyarteritis nodosa (PAN) is a systemic necrotizing vasculitis typically involving small-and mediumsized muscular arteries of visceral and soft tissues.
TextSentencer_T11 1304-1457 Sentence denotes Polyarteritis nodosa (PAN) is a systemic necrotizing vasculitis typically involving small-and mediumsized muscular arteries of visceral and soft tissues.
TextSentencer_T11 1304-1457 Sentence denotes Polyarteritis nodosa (PAN) is a systemic necrotizing vasculitis typically involving small-and mediumsized muscular arteries of visceral and soft tissues.
TextSentencer_T12 1458-1592 Sentence denotes PAN can affect every organ, but generally the lungs are spared; venules and capillaries are not involved (Forbess and Bannykh, 2015) .
TextSentencer_T12 1458-1592 Sentence denotes PAN can affect every organ, but generally the lungs are spared; venules and capillaries are not involved (Forbess and Bannykh, 2015) .
TextSentencer_T12 1458-1592 Sentence denotes PAN can affect every organ, but generally the lungs are spared; venules and capillaries are not involved (Forbess and Bannykh, 2015) .
TextSentencer_T13 1593-1715 Sentence denotes In veterinary medicine, PAN is a common disease of laboratory animals, affecting mainly male rats (Lepherd et al., 2013) .
TextSentencer_T13 1593-1715 Sentence denotes In veterinary medicine, PAN is a common disease of laboratory animals, affecting mainly male rats (Lepherd et al., 2013) .
TextSentencer_T13 1593-1715 Sentence denotes In veterinary medicine, PAN is a common disease of laboratory animals, affecting mainly male rats (Lepherd et al., 2013) .
TextSentencer_T14 1716-2184 Sentence denotes It has been described in blue foxes (Alopex lagopus) (Nordstoga and Westbye, 1976) , cynomolgus macaques (Macaca fascicularis) (Albassam et al., 1993; Porter et al., 2003) , sheep (Landsverk and Bratberg, 1979; Ferreras et al., 2013; Wessel et al., 2017; Pesavento et al., 2018) , cattle (Filippich and Mudie, 1972) , pigs (Hamir, 1980; Liu et al., 2005) , dogs (Carpenter et al., 1988; Snyder et al., 1995) and cats (Altera and Bonasch, 1966; Campbell et al., 1972) .
TextSentencer_T14 1716-2184 Sentence denotes It has been described in blue foxes (Alopex lagopus) (Nordstoga and Westbye, 1976) , cynomolgus macaques (Macaca fascicularis) (Albassam et al., 1993; Porter et al., 2003) , sheep (Landsverk and Bratberg, 1979; Ferreras et al., 2013; Wessel et al., 2017; Pesavento et al., 2018) , cattle (Filippich and Mudie, 1972) , pigs (Hamir, 1980; Liu et al., 2005) , dogs (Carpenter et al., 1988; Snyder et al., 1995) and cats (Altera and Bonasch, 1966; Campbell et al., 1972) .
TextSentencer_T14 1716-2184 Sentence denotes It has been described in blue foxes (Alopex lagopus) (Nordstoga and Westbye, 1976) , cynomolgus macaques (Macaca fascicularis) (Albassam et al., 1993; Porter et al., 2003) , sheep (Landsverk and Bratberg, 1979; Ferreras et al., 2013; Wessel et al., 2017; Pesavento et al., 2018) , cattle (Filippich and Mudie, 1972) , pigs (Hamir, 1980; Liu et al., 2005) , dogs (Carpenter et al., 1988; Snyder et al., 1995) and cats (Altera and Bonasch, 1966; Campbell et al., 1972) .
TextSentencer_T15 2185-2311 Sentence denotes Affected cats were reported to show weight loss, pyrexia, sneezing, leucocytosis, stiffness of all four limbs and muscle pain.
TextSentencer_T15 2185-2311 Sentence denotes Affected cats were reported to show weight loss, pyrexia, sneezing, leucocytosis, stiffness of all four limbs and muscle pain.
TextSentencer_T15 2185-2311 Sentence denotes Affected cats were reported to show weight loss, pyrexia, sneezing, leucocytosis, stiffness of all four limbs and muscle pain.
TextSentencer_T16 2312-2563 Sentence denotes Vascular lesions were detected in many organs including the pancreas, thyroid glands, myocardium, lymph nodes, spleen, liver, kidney, lungs, eyes, skeletal muscles and periarticular connective tissue (Altera and Bonasch, 1966; Campbell et al., 1972) .
TextSentencer_T16 2312-2563 Sentence denotes Vascular lesions were detected in many organs including the pancreas, thyroid glands, myocardium, lymph nodes, spleen, liver, kidney, lungs, eyes, skeletal muscles and periarticular connective tissue (Altera and Bonasch, 1966; Campbell et al., 1972) .
TextSentencer_T16 2312-2563 Sentence denotes Vascular lesions were detected in many organs including the pancreas, thyroid glands, myocardium, lymph nodes, spleen, liver, kidney, lungs, eyes, skeletal muscles and periarticular connective tissue (Altera and Bonasch, 1966; Campbell et al., 1972) .
TextSentencer_T17 2564-2611 Sentence denotes Involvement of nervous tissue was not reported.
TextSentencer_T17 2564-2611 Sentence denotes Involvement of nervous tissue was not reported.
TextSentencer_T17 2564-2611 Sentence denotes Involvement of nervous tissue was not reported.
TextSentencer_T18 2612-2657 Sentence denotes The pathogenesis of PAN is poorly understood.
TextSentencer_T18 2612-2657 Sentence denotes The pathogenesis of PAN is poorly understood.
TextSentencer_T18 2612-2657 Sentence denotes The pathogenesis of PAN is poorly understood.
TextSentencer_T19 2658-2888 Sentence denotes In man, PAN triggered by virus infections such as with hepatitis B and C viruses, human immunodeficiency virus, parvovirus B19 and hairy cell leukaemia has been described (Ishiguro and Kawashima, 2010; Forbess and Bannykh, 2015) .
TextSentencer_T19 2658-2888 Sentence denotes In man, PAN triggered by virus infections such as with hepatitis B and C viruses, human immunodeficiency virus, parvovirus B19 and hairy cell leukaemia has been described (Ishiguro and Kawashima, 2010; Forbess and Bannykh, 2015) .
TextSentencer_T19 2658-2888 Sentence denotes In man, PAN triggered by virus infections such as with hepatitis B and C viruses, human immunodeficiency virus, parvovirus B19 and hairy cell leukaemia has been described (Ishiguro and Kawashima, 2010; Forbess and Bannykh, 2015) .
TextSentencer_T20 2889-3232 Sentence denotes An immune-mediated mechanism in the development of vascular lesions is suspected (Cid et al., 1994; Forbess and Bannykh, 2015) due to the prevalence of macrophages and CD4 + T lymphocytes in inflammatory infiltrates and to the clinical response to immunosuppressive drugs (Eleftheriou et al., 2013; Watanabe et al., 2016; James et al., 2018) .
TextSentencer_T20 2889-3232 Sentence denotes An immune-mediated mechanism in the development of vascular lesions is suspected (Cid et al., 1994; Forbess and Bannykh, 2015) due to the prevalence of macrophages and CD4 + T lymphocytes in inflammatory infiltrates and to the clinical response to immunosuppressive drugs (Eleftheriou et al., 2013; Watanabe et al., 2016; James et al., 2018) .
TextSentencer_T20 2889-3232 Sentence denotes An immune-mediated mechanism in the development of vascular lesions is suspected (Cid et al., 1994; Forbess and Bannykh, 2015) due to the prevalence of macrophages and CD4 + T lymphocytes in inflammatory infiltrates and to the clinical response to immunosuppressive drugs (Eleftheriou et al., 2013; Watanabe et al., 2016; James et al., 2018) .
TextSentencer_T21 3233-3494 Sentence denotes In veterinary medicine, PAN has been described in blue foxes associated with encephalitozoonosis (Nordstoga and Westbye, 1976) , in lambs with sarcocystosis (Landsverk and Bratberg, 1979) and in sheep infected with ovine herpesvirus 2 (Pesavento et al., 2018) .
TextSentencer_T21 3233-3494 Sentence denotes In veterinary medicine, PAN has been described in blue foxes associated with encephalitozoonosis (Nordstoga and Westbye, 1976) , in lambs with sarcocystosis (Landsverk and Bratberg, 1979) and in sheep infected with ovine herpesvirus 2 (Pesavento et al., 2018) .
TextSentencer_T21 3233-3494 Sentence denotes In veterinary medicine, PAN has been described in blue foxes associated with encephalitozoonosis (Nordstoga and Westbye, 1976) , in lambs with sarcocystosis (Landsverk and Bratberg, 1979) and in sheep infected with ovine herpesvirus 2 (Pesavento et al., 2018) .
TextSentencer_T22 3495-3586 Sentence denotes A relationship with streptococcal infection has been suspected in pigs (Liu et al., 2005) .
TextSentencer_T22 3495-3586 Sentence denotes A relationship with streptococcal infection has been suspected in pigs (Liu et al., 2005) .
TextSentencer_T22 3495-3586 Sentence denotes A relationship with streptococcal infection has been suspected in pigs (Liu et al., 2005) .
TextSentencer_T23 3587-3757 Sentence denotes However, no infectious agents have been detected in most cases of PAN in animals (Carpenter et al., 1988; Snyder et al., 1995; Porter et al., 2003; Wessel et al., 2017) .
TextSentencer_T23 3587-3757 Sentence denotes However, no infectious agents have been detected in most cases of PAN in animals (Carpenter et al., 1988; Snyder et al., 1995; Porter et al., 2003; Wessel et al., 2017) .
TextSentencer_T23 3587-3757 Sentence denotes However, no infectious agents have been detected in most cases of PAN in animals (Carpenter et al., 1988; Snyder et al., 1995; Porter et al., 2003; Wessel et al., 2017) .
TextSentencer_T24 3758-3946 Sentence denotes Here we describe the clinical and pathological findings in a case of feline PAN with central and peripheral nervous system involvement not previously reported in the veterinary literature.
TextSentencer_T24 3758-3946 Sentence denotes Here we describe the clinical and pathological findings in a case of feline PAN with central and peripheral nervous system involvement not previously reported in the veterinary literature.
TextSentencer_T24 3758-3946 Sentence denotes Here we describe the clinical and pathological findings in a case of feline PAN with central and peripheral nervous system involvement not previously reported in the veterinary literature.
TextSentencer_T25 3947-4143 Sentence denotes An 18-month-old neutered male domestic shorthair cat was referred with a 2-month history of pyrexia, polyuria and polydypsia, vomiting and three episodes of transient bilateral hindlimb paralysis.
TextSentencer_T25 3947-4143 Sentence denotes An 18-month-old neutered male domestic shorthair cat was referred with a 2-month history of pyrexia, polyuria and polydypsia, vomiting and three episodes of transient bilateral hindlimb paralysis.
TextSentencer_T25 3947-4143 Sentence denotes An 18-month-old neutered male domestic shorthair cat was referred with a 2-month history of pyrexia, polyuria and polydypsia, vomiting and three episodes of transient bilateral hindlimb paralysis.
TextSentencer_T26 4144-4213 Sentence denotes During the last year, recurrent vomiting and diarrhoea were reported.
TextSentencer_T26 4144-4213 Sentence denotes During the last year, recurrent vomiting and diarrhoea were reported.
TextSentencer_T26 4144-4213 Sentence denotes During the last year, recurrent vomiting and diarrhoea were reported.
TextSentencer_T27 4214-4284 Sentence denotes The cat was vaccinated and there was no history of exposure to toxins.
TextSentencer_T27 4214-4284 Sentence denotes The cat was vaccinated and there was no history of exposure to toxins.
TextSentencer_T27 4214-4284 Sentence denotes The cat was vaccinated and there was no history of exposure to toxins.
TextSentencer_T28 4285-4440 Sentence denotes The cat was seronegative for feline infectious peritonitis (FIP), feline leukaemia virus (FeLV), feline immunodeficiency virus (FIV) and Toxoplasma gondii.
TextSentencer_T28 4285-4440 Sentence denotes The cat was seronegative for feline infectious peritonitis (FIP), feline leukaemia virus (FeLV), feline immunodeficiency virus (FIV) and Toxoplasma gondii.
TextSentencer_T28 4285-4440 Sentence denotes The cat was seronegative for feline infectious peritonitis (FIP), feline leukaemia virus (FeLV), feline immunodeficiency virus (FIV) and Toxoplasma gondii.
TextSentencer_T29 4441-4538 Sentence denotes On presentation, the cat was bright, alert and responsive, with a low body condition score (3/9).
TextSentencer_T29 4441-4538 Sentence denotes On presentation, the cat was bright, alert and responsive, with a low body condition score (3/9).
TextSentencer_T29 4441-4538 Sentence denotes On presentation, the cat was bright, alert and responsive, with a low body condition score (3/9).
TextSentencer_T30 4539-4742 Sentence denotes Cardiac auscultation revealed a systolic heart murmur (grade 3/6) with maximal intensity over the sternum and severe systemic hypertension (systolic blood pressure 230 mm Hg; normal range 120e150 mm Hg).
TextSentencer_T30 4539-4742 Sentence denotes Cardiac auscultation revealed a systolic heart murmur (grade 3/6) with maximal intensity over the sternum and severe systemic hypertension (systolic blood pressure 230 mm Hg; normal range 120e150 mm Hg).
TextSentencer_T30 4539-4742 Sentence denotes Cardiac auscultation revealed a systolic heart murmur (grade 3/6) with maximal intensity over the sternum and severe systemic hypertension (systolic blood pressure 230 mm Hg; normal range 120e150 mm Hg).
TextSentencer_T31 4743-4972 Sentence denotes Echocardiography revealed severe concentric hypertrophy of the left ventricle with heterogeneous echogenicity of the myocardium, a left atrium of normal dimensions and a dynamic obstruction of the right ventricular outflow tract.
TextSentencer_T31 4743-4972 Sentence denotes Echocardiography revealed severe concentric hypertrophy of the left ventricle with heterogeneous echogenicity of the myocardium, a left atrium of normal dimensions and a dynamic obstruction of the right ventricular outflow tract.
TextSentencer_T31 4743-4972 Sentence denotes Echocardiography revealed severe concentric hypertrophy of the left ventricle with heterogeneous echogenicity of the myocardium, a left atrium of normal dimensions and a dynamic obstruction of the right ventricular outflow tract.
TextSentencer_T32 4973-5055 Sentence denotes Abdominal ultrasonography revealed chronic intestinal and pancreatic inflammation.
TextSentencer_T32 4973-5055 Sentence denotes Abdominal ultrasonography revealed chronic intestinal and pancreatic inflammation.
TextSentencer_T32 4973-5055 Sentence denotes Abdominal ultrasonography revealed chronic intestinal and pancreatic inflammation.
TextSentencer_T33 5056-5098 Sentence denotes Neurological examination was unremarkable.
TextSentencer_T33 5056-5098 Sentence denotes Neurological examination was unremarkable.
TextSentencer_T33 5056-5098 Sentence denotes Neurological examination was unremarkable.
TextSentencer_T34 5099-5156 Sentence denotes Complete blood count and coagulation profile were normal.
TextSentencer_T34 5099-5156 Sentence denotes Complete blood count and coagulation profile were normal.
TextSentencer_T34 5099-5156 Sentence denotes Complete blood count and coagulation profile were normal.
TextSentencer_T35 5157-5286 Sentence denotes Serum electrophoresis showed a moderate hyperproteinaemia (9 g/dl, reference interval 6e8 g/ dl) with alpha-2 hyperglobulinaemia.
TextSentencer_T35 5157-5286 Sentence denotes Serum electrophoresis showed a moderate hyperproteinaemia (9 g/dl, reference interval 6e8 g/ dl) with alpha-2 hyperglobulinaemia.
TextSentencer_T35 5157-5286 Sentence denotes Serum electrophoresis showed a moderate hyperproteinaemia (9 g/dl, reference interval 6e8 g/ dl) with alpha-2 hyperglobulinaemia.
TextSentencer_T36 5287-5414 Sentence denotes Serum cardiac troponin I was 0 ng/ml (reference interval 0e0.11 ng/ ml) and concentrations of cobalamin and folate were normal.
TextSentencer_T36 5287-5414 Sentence denotes Serum cardiac troponin I was 0 ng/ml (reference interval 0e0.11 ng/ ml) and concentrations of cobalamin and folate were normal.
TextSentencer_T36 5287-5414 Sentence denotes Serum cardiac troponin I was 0 ng/ml (reference interval 0e0.11 ng/ ml) and concentrations of cobalamin and folate were normal.
TextSentencer_T37 5415-5503 Sentence denotes Low urine specificity gravity (1.012; reference interval 1.035e1.060) was also detected.
TextSentencer_T37 5415-5503 Sentence denotes Low urine specificity gravity (1.012; reference interval 1.035e1.060) was also detected.
TextSentencer_T37 5415-5503 Sentence denotes Low urine specificity gravity (1.012; reference interval 1.035e1.060) was also detected.
TextSentencer_T38 5504-5879 Sentence denotes After these diagnostic investigations, the cat was discharged on amlodipine 0.2 mg/kg q24h for systemic hypertension, clopidogrel 1 mg/kg q24h as an antithrombotic drug, probiotics (feline Fortiflora Ò ProPlan Ò Veterinary Diets; Nestl e Purina, St. Louis, Missouri, USA) and a gastrointestinal diet (feline EN Gastro-intestinalÔ Pro Plan Ò Veterinary Diets; Nestl e Purina).
TextSentencer_T38 5504-5879 Sentence denotes After these diagnostic investigations, the cat was discharged on amlodipine 0.2 mg/kg q24h for systemic hypertension, clopidogrel 1 mg/kg q24h as an antithrombotic drug, probiotics (feline Fortiflora Ò ProPlan Ò Veterinary Diets; Nestl e Purina, St. Louis, Missouri, USA) and a gastrointestinal diet (feline EN Gastro-intestinalÔ Pro Plan Ò Veterinary Diets; Nestl e Purina).
TextSentencer_T38 5504-5879 Sentence denotes After these diagnostic investigations, the cat was discharged on amlodipine 0.2 mg/kg q24h for systemic hypertension, clopidogrel 1 mg/kg q24h as an antithrombotic drug, probiotics (feline Fortiflora Ò ProPlan Ò Veterinary Diets; Nestl e Purina, St. Louis, Missouri, USA) and a gastrointestinal diet (feline EN Gastro-intestinalÔ Pro Plan Ò Veterinary Diets; Nestl e Purina).
TextSentencer_T39 5880-6058 Sentence denotes After 1 week of therapy, the cat appeared to have improved clinically, but the systolic blood pressure was still high, and the dose of amlodipine was increased to 0.2 mg/kg q12h.
TextSentencer_T39 5880-6058 Sentence denotes After 1 week of therapy, the cat appeared to have improved clinically, but the systolic blood pressure was still high, and the dose of amlodipine was increased to 0.2 mg/kg q12h.
TextSentencer_T39 5880-6058 Sentence denotes After 1 week of therapy, the cat appeared to have improved clinically, but the systolic blood pressure was still high, and the dose of amlodipine was increased to 0.2 mg/kg q12h.
TextSentencer_T40 6059-6202 Sentence denotes One month later the cat was readmitted with a new episode of hindlimb paralysis with bilateral loss of patellar reflex and reduced nociception.
TextSentencer_T40 6059-6202 Sentence denotes One month later the cat was readmitted with a new episode of hindlimb paralysis with bilateral loss of patellar reflex and reduced nociception.
TextSentencer_T40 6059-6202 Sentence denotes One month later the cat was readmitted with a new episode of hindlimb paralysis with bilateral loss of patellar reflex and reduced nociception.
TextSentencer_T41 6203-6269 Sentence denotes The cat also showed circling, vocalization and recurrent seizures.
TextSentencer_T41 6203-6269 Sentence denotes The cat also showed circling, vocalization and recurrent seizures.
TextSentencer_T41 6203-6269 Sentence denotes The cat also showed circling, vocalization and recurrent seizures.
TextSentencer_T42 6270-6321 Sentence denotes The cat died in status epilepticus on the same day.
TextSentencer_T42 6270-6321 Sentence denotes The cat died in status epilepticus on the same day.
TextSentencer_T42 6270-6321 Sentence denotes The cat died in status epilepticus on the same day.
TextSentencer_T43 6322-6482 Sentence denotes A complete necropsy examination was performed and gross changes were evident in the heart, kidneys and at the aortic bifurcation into the common iliac arteries.
TextSentencer_T43 6322-6482 Sentence denotes A complete necropsy examination was performed and gross changes were evident in the heart, kidneys and at the aortic bifurcation into the common iliac arteries.
TextSentencer_T43 6322-6482 Sentence denotes A complete necropsy examination was performed and gross changes were evident in the heart, kidneys and at the aortic bifurcation into the common iliac arteries.
TextSentencer_T44 6483-6643 Sentence denotes Coronary arteries, mainly the left coronary artery and its branches, showed marked thickening with small nodules located segmentally along the vessel (Fig. 1) .
TextSentencer_T44 6483-6643 Sentence denotes Coronary arteries, mainly the left coronary artery and its branches, showed marked thickening with small nodules located segmentally along the vessel (Fig. 1) .
TextSentencer_T44 6483-6643 Sentence denotes Coronary arteries, mainly the left coronary artery and its branches, showed marked thickening with small nodules located segmentally along the vessel (Fig. 1) .
TextSentencer_T45 6644-6910 Sentence denotes In transverse sections, moderate symmetrical thickening of the left ventricular free wall and interventricular septum with narrowing of the lumen were evident; coronary arteries showed severe thickening and hardening of the walls with marked narrowing of the lumina.
TextSentencer_T45 6644-6910 Sentence denotes In transverse sections, moderate symmetrical thickening of the left ventricular free wall and interventricular septum with narrowing of the lumen were evident; coronary arteries showed severe thickening and hardening of the walls with marked narrowing of the lumina.
TextSentencer_T45 6644-6910 Sentence denotes In transverse sections, moderate symmetrical thickening of the left ventricular free wall and interventricular septum with narrowing of the lumen were evident; coronary arteries showed severe thickening and hardening of the walls with marked narrowing of the lumina.
TextSentencer_T46 6911-7005 Sentence denotes No haemorrhages were detected, but there was multifocal pale discolouration of the myocardium.
TextSentencer_T46 6911-7005 Sentence denotes No haemorrhages were detected, but there was multifocal pale discolouration of the myocardium.
TextSentencer_T46 6911-7005 Sentence denotes No haemorrhages were detected, but there was multifocal pale discolouration of the myocardium.
TextSentencer_T47 7006-7073 Sentence denotes The kidneys showed an irregular surface with multifocal pale scars.
TextSentencer_T47 7006-7073 Sentence denotes The kidneys showed an irregular surface with multifocal pale scars.
TextSentencer_T47 7006-7073 Sentence denotes The kidneys showed an irregular surface with multifocal pale scars.
TextSentencer_T48 7074-7299 Sentence denotes Thinning and discolouration of the cortex and marked thickening of the arcuate arteries, with these vessels having a tortuous course and segmental nodular change, were evident on longitudinal sections of both kidneys Fig. 1 .
TextSentencer_T48 7074-7299 Sentence denotes Thinning and discolouration of the cortex and marked thickening of the arcuate arteries, with these vessels having a tortuous course and segmental nodular change, were evident on longitudinal sections of both kidneys Fig. 1 .
TextSentencer_T48 7074-7299 Sentence denotes Thinning and discolouration of the cortex and marked thickening of the arcuate arteries, with these vessels having a tortuous course and segmental nodular change, were evident on longitudinal sections of both kidneys Fig. 1 .
TextSentencer_T49 7300-7306 Sentence denotes Heart.
TextSentencer_T49 7300-7306 Sentence denotes Heart.
TextSentencer_T49 7300-7306 Sentence denotes Heart.
TextSentencer_T50 7307-7410 Sentence denotes The left coronary artery and its branches show severe thickening and small nodules located segmentally.
TextSentencer_T50 7307-7410 Sentence denotes The left coronary artery and its branches show severe thickening and small nodules located segmentally.
TextSentencer_T50 7307-7410 Sentence denotes The left coronary artery and its branches show severe thickening and small nodules located segmentally.
TextSentencer_T51 7411-7421 Sentence denotes Bar, 1 cm.
TextSentencer_T51 7411-7421 Sentence denotes Bar, 1 cm.
TextSentencer_T51 7411-7421 Sentence denotes Bar, 1 cm.
TextSentencer_T52 7422-7447 Sentence denotes ( Supplementary Fig. 1 ).
TextSentencer_T52 7422-7447 Sentence denotes ( Supplementary Fig. 1 ).
TextSentencer_T52 7422-7447 Sentence denotes ( Supplementary Fig. 1 ).
TextSentencer_T53 7448-7604 Sentence denotes Segmental nodular thickening was also evident in the common iliac arteries (especially that of the right side) and at the terminal bifurcation of the aorta.
TextSentencer_T53 7448-7604 Sentence denotes Segmental nodular thickening was also evident in the common iliac arteries (especially that of the right side) and at the terminal bifurcation of the aorta.
TextSentencer_T53 7448-7604 Sentence denotes Segmental nodular thickening was also evident in the common iliac arteries (especially that of the right side) and at the terminal bifurcation of the aorta.
TextSentencer_T54 7605-7749 Sentence denotes Samples of major organs, the aortic and iliac arteries and the entire central nervous system (CNS) were fixed in 4% phosphate buffered formalin.
TextSentencer_T54 7605-7749 Sentence denotes Samples of major organs, the aortic and iliac arteries and the entire central nervous system (CNS) were fixed in 4% phosphate buffered formalin.
TextSentencer_T54 7605-7749 Sentence denotes Samples of major organs, the aortic and iliac arteries and the entire central nervous system (CNS) were fixed in 4% phosphate buffered formalin.
TextSentencer_T55 7750-8016 Sentence denotes Samples of the right and left cranial tibial and triceps muscles were snap frozen in isopentane precooled in liquid nitrogen and samples of the right and left peroneal common nerves and ulnar nerves were fixed in 2.5% glutaraldehyde in 0.1 M phosphate buffer at 4 C.
TextSentencer_T55 7750-8016 Sentence denotes Samples of the right and left cranial tibial and triceps muscles were snap frozen in isopentane precooled in liquid nitrogen and samples of the right and left peroneal common nerves and ulnar nerves were fixed in 2.5% glutaraldehyde in 0.1 M phosphate buffer at 4 C.
TextSentencer_T55 7750-8016 Sentence denotes Samples of the right and left cranial tibial and triceps muscles were snap frozen in isopentane precooled in liquid nitrogen and samples of the right and left peroneal common nerves and ulnar nerves were fixed in 2.5% glutaraldehyde in 0.1 M phosphate buffer at 4 C.
TextSentencer_T56 8017-8094 Sentence denotes Formalin-fixed tissues were processed routinely and embedded in paraffin wax.
TextSentencer_T56 8017-8094 Sentence denotes Formalin-fixed tissues were processed routinely and embedded in paraffin wax.
TextSentencer_T56 8017-8094 Sentence denotes Formalin-fixed tissues were processed routinely and embedded in paraffin wax.
TextSentencer_T57 8095-8256 Sentence denotes Sections were stained with haematoxylin and eosin (HE), periodic acideSchiff (PAS), Luxol fast blue, Gomori's trichrome, orcein and Perls' Prussian blue methods.
TextSentencer_T57 8095-8256 Sentence denotes Sections were stained with haematoxylin and eosin (HE), periodic acideSchiff (PAS), Luxol fast blue, Gomori's trichrome, orcein and Perls' Prussian blue methods.
TextSentencer_T57 8095-8256 Sentence denotes Sections were stained with haematoxylin and eosin (HE), periodic acideSchiff (PAS), Luxol fast blue, Gomori's trichrome, orcein and Perls' Prussian blue methods.
TextSentencer_T58 8257-8887 Sentence denotes Selected sections were labelled immunohistochemically with antibodies specific for CD3 (clone F7.2.38; 1 in 100 dilution; Dako, Glostrup, Denmark), CD20 (RB9013; 1 in 400 dilution; Thermo Scientific, Fremont, California, USA), Iba-1 (1 in 300 dilution; Wako, Osaka, Japan), major histocompatibility complex class II (MHC class II; clone 1AL.1B5; 1 in 10 dilution; Dako), feline IgG, IgM and complement factor C3 (each 1 in 10 dilution; Binding Site, Birmingham, UK), feline coronavirus (FIPV3-70; 1 in 200 dilution; OriGene Technologies Inc., Rockville, Maryland, USA) and smooth muscle actin (clone 1A4; 1 in 500 dilution; Dako).
TextSentencer_T58 8257-8887 Sentence denotes Selected sections were labelled immunohistochemically with antibodies specific for CD3 (clone F7.2.38; 1 in 100 dilution; Dako, Glostrup, Denmark), CD20 (RB9013; 1 in 400 dilution; Thermo Scientific, Fremont, California, USA), Iba-1 (1 in 300 dilution; Wako, Osaka, Japan), major histocompatibility complex class II (MHC class II; clone 1AL.1B5; 1 in 10 dilution; Dako), feline IgG, IgM and complement factor C3 (each 1 in 10 dilution; Binding Site, Birmingham, UK), feline coronavirus (FIPV3-70; 1 in 200 dilution; OriGene Technologies Inc., Rockville, Maryland, USA) and smooth muscle actin (clone 1A4; 1 in 500 dilution; Dako).
TextSentencer_T58 8257-8887 Sentence denotes Selected sections were labelled immunohistochemically with antibodies specific for CD3 (clone F7.2.38; 1 in 100 dilution; Dako, Glostrup, Denmark), CD20 (RB9013; 1 in 400 dilution; Thermo Scientific, Fremont, California, USA), Iba-1 (1 in 300 dilution; Wako, Osaka, Japan), major histocompatibility complex class II (MHC class II; clone 1AL.1B5; 1 in 10 dilution; Dako), feline IgG, IgM and complement factor C3 (each 1 in 10 dilution; Binding Site, Birmingham, UK), feline coronavirus (FIPV3-70; 1 in 200 dilution; OriGene Technologies Inc., Rockville, Maryland, USA) and smooth muscle actin (clone 1A4; 1 in 500 dilution; Dako).
TextSentencer_T59 8888-9039 Sentence denotes Cryostat sections (8 mm) of frozen muscle were evaluated using a standard panel of histochemical stains and enzyme reactions (Salvadori et al., 2012) .
TextSentencer_T59 8888-9039 Sentence denotes Cryostat sections (8 mm) of frozen muscle were evaluated using a standard panel of histochemical stains and enzyme reactions (Salvadori et al., 2012) .
TextSentencer_T59 8888-9039 Sentence denotes Cryostat sections (8 mm) of frozen muscle were evaluated using a standard panel of histochemical stains and enzyme reactions (Salvadori et al., 2012) .
TextSentencer_T60 9040-9134 Sentence denotes Nerves were post-fixed in osmium tetroxide, dehydrated in ethanol and embedded in epoxy resin.
TextSentencer_T60 9040-9134 Sentence denotes Nerves were post-fixed in osmium tetroxide, dehydrated in ethanol and embedded in epoxy resin.
TextSentencer_T60 9040-9134 Sentence denotes Nerves were post-fixed in osmium tetroxide, dehydrated in ethanol and embedded in epoxy resin.
TextSentencer_T61 9135-9227 Sentence denotes Semithin sections were stained with toluidine blue and methylene blue/basic fuchsin methods.
TextSentencer_T61 9135-9227 Sentence denotes Semithin sections were stained with toluidine blue and methylene blue/basic fuchsin methods.
TextSentencer_T61 9135-9227 Sentence denotes Semithin sections were stained with toluidine blue and methylene blue/basic fuchsin methods.
TextSentencer_T62 9228-9490 Sentence denotes Microscopical examination revealed multifocal peri-and panarteritis involving small, medium and large arteries of the heart, kidney, small and large intestine, mesentery, liver, thyroid gland, brain and spinal meninges (Fig. 2) , and peripheral nerves (Fig. 3) .
TextSentencer_T62 9228-9490 Sentence denotes Microscopical examination revealed multifocal peri-and panarteritis involving small, medium and large arteries of the heart, kidney, small and large intestine, mesentery, liver, thyroid gland, brain and spinal meninges (Fig. 2) , and peripheral nerves (Fig. 3) .
TextSentencer_T62 9228-9490 Sentence denotes Microscopical examination revealed multifocal peri-and panarteritis involving small, medium and large arteries of the heart, kidney, small and large intestine, mesentery, liver, thyroid gland, brain and spinal meninges (Fig. 2) , and peripheral nerves (Fig. 3) .
TextSentencer_T63 9491-9836 Sentence denotes Inflammatory cells, mainly MHC class II-positive cells, with higher numbers of T lymphocytes ( Supplementary Fig. 2 ) and macrophages ( Supplementary Fig. 3 ) and fewer CD20-positive lymphocytes, plasma cells and rare neutrophils, infiltrated the adventitia and perivascular tissues, spreading within the artery wall to the subendothelial layer.
TextSentencer_T63 9491-9836 Sentence denotes Inflammatory cells, mainly MHC class II-positive cells, with higher numbers of T lymphocytes ( Supplementary Fig. 2 ) and macrophages ( Supplementary Fig. 3 ) and fewer CD20-positive lymphocytes, plasma cells and rare neutrophils, infiltrated the adventitia and perivascular tissues, spreading within the artery wall to the subendothelial layer.
TextSentencer_T63 9491-9836 Sentence denotes Inflammatory cells, mainly MHC class II-positive cells, with higher numbers of T lymphocytes ( Supplementary Fig. 2 ) and macrophages ( Supplementary Fig. 3 ) and fewer CD20-positive lymphocytes, plasma cells and rare neutrophils, infiltrated the adventitia and perivascular tissues, spreading within the artery wall to the subendothelial layer.
TextSentencer_T64 9837-9913 Sentence denotes Both IgG-and IgM-labelled plasma cells were evident, but no C3 was detected.
TextSentencer_T64 9837-9913 Sentence denotes Both IgG-and IgM-labelled plasma cells were evident, but no C3 was detected.
TextSentencer_T64 9837-9913 Sentence denotes Both IgG-and IgM-labelled plasma cells were evident, but no C3 was detected.
TextSentencer_T65 9914-10128 Sentence denotes Inflammatory cell infiltration was associated with necrosis and loss of smooth muscle fibres of the tunica media and delamination and disintegration of the internal and external elastic laminae (Supplementary Figs.
TextSentencer_T65 9914-10128 Sentence denotes Inflammatory cell infiltration was associated with necrosis and loss of smooth muscle fibres of the tunica media and delamination and disintegration of the internal and external elastic laminae (Supplementary Figs.
TextSentencer_T65 9914-10128 Sentence denotes Inflammatory cell infiltration was associated with necrosis and loss of smooth muscle fibres of the tunica media and delamination and disintegration of the internal and external elastic laminae (Supplementary Figs.
TextSentencer_T66 10129-10139 Sentence denotes 4 and 5) .
TextSentencer_T66 10129-10139 Sentence denotes 4 and 5) .
TextSentencer_T66 10129-10139 Sentence denotes 4 and 5) .
TextSentencer_T67 10140-10280 Sentence denotes Different stages of vascular inflammation were evident in the same tissue and the coexistence of affected and unaffected vessels was common.
TextSentencer_T67 10140-10280 Sentence denotes Different stages of vascular inflammation were evident in the same tissue and the coexistence of affected and unaffected vessels was common.
TextSentencer_T67 10140-10280 Sentence denotes Different stages of vascular inflammation were evident in the same tissue and the coexistence of affected and unaffected vessels was common.
TextSentencer_T68 10281-10527 Sentence denotes Acute stages, with fibrinoid necrosis of the tunica media and a dominant infiltration of neutrophils ( Supplementary Fig. 6 ), were associated with chronic stages characterized by severe thickening of the arterial wall and narrowing of the lumen.
TextSentencer_T68 10281-10527 Sentence denotes Acute stages, with fibrinoid necrosis of the tunica media and a dominant infiltration of neutrophils ( Supplementary Fig. 6 ), were associated with chronic stages characterized by severe thickening of the arterial wall and narrowing of the lumen.
TextSentencer_T68 10281-10527 Sentence denotes Acute stages, with fibrinoid necrosis of the tunica media and a dominant infiltration of neutrophils ( Supplementary Fig. 6 ), were associated with chronic stages characterized by severe thickening of the arterial wall and narrowing of the lumen.
TextSentencer_T69 10528-10721 Sentence denotes In severely thickened vessels, both the intima and tunica media showed marked proliferation of fibroblasts and hyperplasia and hypertrophy of smooth muscle (Fig. 4) , with extracellular oedema.
TextSentencer_T69 10528-10721 Sentence denotes In severely thickened vessels, both the intima and tunica media showed marked proliferation of fibroblasts and hyperplasia and hypertrophy of smooth muscle (Fig. 4) , with extracellular oedema.
TextSentencer_T69 10528-10721 Sentence denotes In severely thickened vessels, both the intima and tunica media showed marked proliferation of fibroblasts and hyperplasia and hypertrophy of smooth muscle (Fig. 4) , with extracellular oedema.
TextSentencer_T70 10722-10769 Sentence denotes Intramural neovascularization was also evident.
TextSentencer_T70 10722-10769 Sentence denotes Intramural neovascularization was also evident.
TextSentencer_T70 10722-10769 Sentence denotes Intramural neovascularization was also evident.
TextSentencer_T71 10770-10881 Sentence denotes Rarely, intraluminal thrombi and haemosiderin-laden macrophages, suggesting previous haemorrhage, were evident.
TextSentencer_T71 10770-10881 Sentence denotes Rarely, intraluminal thrombi and haemosiderin-laden macrophages, suggesting previous haemorrhage, were evident.
TextSentencer_T71 10770-10881 Sentence denotes Rarely, intraluminal thrombi and haemosiderin-laden macrophages, suggesting previous haemorrhage, were evident.
TextSentencer_T72 10882-10942 Sentence denotes The most severe vascular lesions were detected in the heart.
TextSentencer_T72 10882-10942 Sentence denotes The most severe vascular lesions were detected in the heart.
TextSentencer_T72 10882-10942 Sentence denotes The most severe vascular lesions were detected in the heart.
TextSentencer_T73 10943-11092 Sentence denotes Coronary arteries and all of their branches in the myocardium showed severe inflammatory changes associated with marked thickening of arterial walls.
TextSentencer_T73 10943-11092 Sentence denotes Coronary arteries and all of their branches in the myocardium showed severe inflammatory changes associated with marked thickening of arterial walls.
TextSentencer_T73 10943-11092 Sentence denotes Coronary arteries and all of their branches in the myocardium showed severe inflammatory changes associated with marked thickening of arterial walls.
TextSentencer_T74 11093-11213 Sentence denotes Multifocal to coalescing fibrosis was also evident in the perimysial and endomysial connective tissue of the myocardium.
TextSentencer_T74 11093-11213 Sentence denotes Multifocal to coalescing fibrosis was also evident in the perimysial and endomysial connective tissue of the myocardium.
TextSentencer_T74 11093-11213 Sentence denotes Multifocal to coalescing fibrosis was also evident in the perimysial and endomysial connective tissue of the myocardium.
TextSentencer_T75 11214-11360 Sentence denotes In both kidneys, severe vascular lesions were associated with multifocal interstitial nephritis and fibrosis without involvement of the glomeruli.
TextSentencer_T75 11214-11360 Sentence denotes In both kidneys, severe vascular lesions were associated with multifocal interstitial nephritis and fibrosis without involvement of the glomeruli.
TextSentencer_T75 11214-11360 Sentence denotes In both kidneys, severe vascular lesions were associated with multifocal interstitial nephritis and fibrosis without involvement of the glomeruli.
TextSentencer_T76 11361-11478 Sentence denotes In the small and large intestine, arterial vessels of the external and internal muscular layers were mainly affected.
TextSentencer_T76 11361-11478 Sentence denotes In the small and large intestine, arterial vessels of the external and internal muscular layers were mainly affected.
TextSentencer_T76 11361-11478 Sentence denotes In the small and large intestine, arterial vessels of the external and internal muscular layers were mainly affected.
TextSentencer_T77 11479-11693 Sentence denotes In the CNS, both the dura mater and leptomeninges were involved, with scattered vascular lesions, mainly located in the spinal cord and ventral aspect of the thalamus, midbrain, medulla oblongata and frontal lobes.
TextSentencer_T77 11479-11693 Sentence denotes In the CNS, both the dura mater and leptomeninges were involved, with scattered vascular lesions, mainly located in the spinal cord and ventral aspect of the thalamus, midbrain, medulla oblongata and frontal lobes.
TextSentencer_T77 11479-11693 Sentence denotes In the CNS, both the dura mater and leptomeninges were involved, with scattered vascular lesions, mainly located in the spinal cord and ventral aspect of the thalamus, midbrain, medulla oblongata and frontal lobes.
TextSentencer_T78 11694-11817 Sentence denotes Lesions were accompanied by scattered inflammatory cells in the meninges and a focal infarct in the ventral frontal cortex.
TextSentencer_T78 11694-11817 Sentence denotes Lesions were accompanied by scattered inflammatory cells in the meninges and a focal infarct in the ventral frontal cortex.
TextSentencer_T78 11694-11817 Sentence denotes Lesions were accompanied by scattered inflammatory cells in the meninges and a focal infarct in the ventral frontal cortex.
TextSentencer_T79 11818-12018 Sentence denotes This latter lesion was associated with affected vessels of the meninges and was characterized by malacia and white matter degeneration, gliosis and infiltration of macrophages laden with haemosiderin.
TextSentencer_T79 11818-12018 Sentence denotes This latter lesion was associated with affected vessels of the meninges and was characterized by malacia and white matter degeneration, gliosis and infiltration of macrophages laden with haemosiderin.
TextSentencer_T79 11818-12018 Sentence denotes This latter lesion was associated with affected vessels of the meninges and was characterized by malacia and white matter degeneration, gliosis and infiltration of macrophages laden with haemosiderin.
TextSentencer_T80 12019-12325 Sentence denotes Both ulnar and common peroneal nerves showed different stages of inflammation of epineural small and medium arteries, ranging from mild perivascular mononuclear cell infiltration to severe thickening of the intima and tunica media with destruction of the elastic lamina ( Fig. 3 and Supplementary Fig. 5 ).
TextSentencer_T80 12019-12325 Sentence denotes Both ulnar and common peroneal nerves showed different stages of inflammation of epineural small and medium arteries, ranging from mild perivascular mononuclear cell infiltration to severe thickening of the intima and tunica media with destruction of the elastic lamina ( Fig. 3 and Supplementary Fig. 5 ).
TextSentencer_T80 12019-12325 Sentence denotes Both ulnar and common peroneal nerves showed different stages of inflammation of epineural small and medium arteries, ranging from mild perivascular mononuclear cell infiltration to severe thickening of the intima and tunica media with destruction of the elastic lamina ( Fig. 3 and Supplementary Fig. 5 ).
TextSentencer_T81 12326-12459 Sentence denotes Vascular lesions were associated with axonal degeneration and a slight loss of large and medium myelinated fibres of nerve fascicles.
TextSentencer_T81 12326-12459 Sentence denotes Vascular lesions were associated with axonal degeneration and a slight loss of large and medium myelinated fibres of nerve fascicles.
TextSentencer_T81 12326-12459 Sentence denotes Vascular lesions were associated with axonal degeneration and a slight loss of large and medium myelinated fibres of nerve fascicles.
TextSentencer_T82 12460-12666 Sentence denotes In muscle samples, there was moderate variation in muscle fibre size and shape, mainly in the cranial tibial muscle, in which there were many angular or rounded atrophic fibres and rare hypertrophic fibres.
TextSentencer_T82 12460-12666 Sentence denotes In muscle samples, there was moderate variation in muscle fibre size and shape, mainly in the cranial tibial muscle, in which there were many angular or rounded atrophic fibres and rare hypertrophic fibres.
TextSentencer_T82 12460-12666 Sentence denotes In muscle samples, there was moderate variation in muscle fibre size and shape, mainly in the cranial tibial muscle, in which there were many angular or rounded atrophic fibres and rare hypertrophic fibres.
TextSentencer_T83 12667-12753 Sentence denotes Rounded atrophic fibres were frequently observed at the periphery of muscle fascicles.
TextSentencer_T83 12667-12753 Sentence denotes Rounded atrophic fibres were frequently observed at the periphery of muscle fascicles.
TextSentencer_T83 12667-12753 Sentence denotes Rounded atrophic fibres were frequently observed at the periphery of muscle fascicles.
TextSentencer_T84 12754-12830 Sentence denotes No fibrosis or inflammatory infiltrates were observed in the muscle samples.
TextSentencer_T84 12754-12830 Sentence denotes No fibrosis or inflammatory infiltrates were observed in the muscle samples.
TextSentencer_T84 12754-12830 Sentence denotes No fibrosis or inflammatory infiltrates were observed in the muscle samples.
TextSentencer_T85 12831-12902 Sentence denotes Myofibre type distribution and enzymatic oxidative pattern were normal.
TextSentencer_T85 12831-12902 Sentence denotes Myofibre type distribution and enzymatic oxidative pattern were normal.
TextSentencer_T85 12831-12902 Sentence denotes Myofibre type distribution and enzymatic oxidative pattern were normal.
TextSentencer_T86 12903-13021 Sentence denotes No lesions were observed in the lungs and no intralesional bacteria, protozoa or fungi were identified in any tissues.
TextSentencer_T86 12903-13021 Sentence denotes No lesions were observed in the lungs and no intralesional bacteria, protozoa or fungi were identified in any tissues.
TextSentencer_T86 12903-13021 Sentence denotes No lesions were observed in the lungs and no intralesional bacteria, protozoa or fungi were identified in any tissues.
TextSentencer_T87 13022-13094 Sentence denotes Immunolabelling for FIP coronavirus antigen was negative in all tissues.
TextSentencer_T87 13022-13094 Sentence denotes Immunolabelling for FIP coronavirus antigen was negative in all tissues.
TextSentencer_T87 13022-13094 Sentence denotes Immunolabelling for FIP coronavirus antigen was negative in all tissues.
TextSentencer_T88 13095-13329 Sentence denotes The pathological findings in this cat were consistent with PAN as described previously in cats and in other species (Altera and Bonasch, 1966; Campbell et al., 1972; Albassam et al., 1993; Porter et al., 2003; Ferreras et al., 2013) .
TextSentencer_T88 13095-13329 Sentence denotes The pathological findings in this cat were consistent with PAN as described previously in cats and in other species (Altera and Bonasch, 1966; Campbell et al., 1972; Albassam et al., 1993; Porter et al., 2003; Ferreras et al., 2013) .
TextSentencer_T88 13095-13329 Sentence denotes The pathological findings in this cat were consistent with PAN as described previously in cats and in other species (Altera and Bonasch, 1966; Campbell et al., 1972; Albassam et al., 1993; Porter et al., 2003; Ferreras et al., 2013) .
TextSentencer_T89 13330-13472 Sentence denotes Involvement of the lungs and eyes was absent, in contrast with other reported feline cases (Altera and Bonasch, 1966; Campbell et al., 1972) .
TextSentencer_T89 13330-13472 Sentence denotes Involvement of the lungs and eyes was absent, in contrast with other reported feline cases (Altera and Bonasch, 1966; Campbell et al., 1972) .
TextSentencer_T89 13330-13472 Sentence denotes Involvement of the lungs and eyes was absent, in contrast with other reported feline cases (Altera and Bonasch, 1966; Campbell et al., 1972) .
TextSentencer_T90 13473-13678 Sentence denotes Although some authors proposed the term 'systemic necrotizing arteritis' instead of PAN (Robinson and Robinson, 2016) , the present cat showed lesions strongly resembling those described in human patients.
TextSentencer_T90 13473-13678 Sentence denotes Although some authors proposed the term 'systemic necrotizing arteritis' instead of PAN (Robinson and Robinson, 2016) , the present cat showed lesions strongly resembling those described in human patients.
TextSentencer_T90 13473-13678 Sentence denotes Although some authors proposed the term 'systemic necrotizing arteritis' instead of PAN (Robinson and Robinson, 2016) , the present cat showed lesions strongly resembling those described in human patients.
TextSentencer_T91 13679-14071 Sentence denotes Involvement of small-and mediumsized arteries showing severe segmental nodular thickening with marked perivascular and intramural mononuclear inflammatory cell infiltration, as well as the presence of affected and unaffected blood vessels within the same tissue, sparing of the lungs, and preference for arterial branching, are all specific features of human PAN (Forbess and Bannykh, 2015) .
TextSentencer_T91 13679-14071 Sentence denotes Involvement of small-and mediumsized arteries showing severe segmental nodular thickening with marked perivascular and intramural mononuclear inflammatory cell infiltration, as well as the presence of affected and unaffected blood vessels within the same tissue, sparing of the lungs, and preference for arterial branching, are all specific features of human PAN (Forbess and Bannykh, 2015) .
TextSentencer_T91 13679-14071 Sentence denotes Involvement of small-and mediumsized arteries showing severe segmental nodular thickening with marked perivascular and intramural mononuclear inflammatory cell infiltration, as well as the presence of affected and unaffected blood vessels within the same tissue, sparing of the lungs, and preference for arterial branching, are all specific features of human PAN (Forbess and Bannykh, 2015) .
TextSentencer_T92 14072-14322 Sentence denotes A prevalence of T lymphocytes and macrophages with a high number of MHC II-labelled cells and scattered IgM-and IgG-labelled plasma cells was detected in our cat as previously described (Porter et al., 2003; Liu et al., 2005; Ferreras et al., 2013) .
TextSentencer_T92 14072-14322 Sentence denotes A prevalence of T lymphocytes and macrophages with a high number of MHC II-labelled cells and scattered IgM-and IgG-labelled plasma cells was detected in our cat as previously described (Porter et al., 2003; Liu et al., 2005; Ferreras et al., 2013) .
TextSentencer_T92 14072-14322 Sentence denotes A prevalence of T lymphocytes and macrophages with a high number of MHC II-labelled cells and scattered IgM-and IgG-labelled plasma cells was detected in our cat as previously described (Porter et al., 2003; Liu et al., 2005; Ferreras et al., 2013) .
TextSentencer_T93 14323-14423 Sentence denotes A cellmediated immune mechanism was suspected, similar to that described in man (Cid et al., 1994) .
TextSentencer_T93 14323-14423 Sentence denotes A cellmediated immune mechanism was suspected, similar to that described in man (Cid et al., 1994) .
TextSentencer_T93 14323-14423 Sentence denotes A cellmediated immune mechanism was suspected, similar to that described in man (Cid et al., 1994) .
TextSentencer_T94 14424-14530 Sentence denotes Although no complement deposition was detected, an immune complex-mediated disorder could not be excluded.
TextSentencer_T94 14424-14530 Sentence denotes Although no complement deposition was detected, an immune complex-mediated disorder could not be excluded.
TextSentencer_T94 14424-14530 Sentence denotes Although no complement deposition was detected, an immune complex-mediated disorder could not be excluded.
TextSentencer_T95 14531-14655 Sentence denotes Indeed, the observed lesions could result from a progression of immune mechanisms from type III to type IV hypersensitivity.
TextSentencer_T95 14531-14655 Sentence denotes Indeed, the observed lesions could result from a progression of immune mechanisms from type III to type IV hypersensitivity.
TextSentencer_T95 14531-14655 Sentence denotes Indeed, the observed lesions could result from a progression of immune mechanisms from type III to type IV hypersensitivity.
TextSentencer_T96 14656-14898 Sentence denotes Prolonged inflammatory vascular injury stimulates proliferation of smooth muscle cells, deposits of extracellular matrix and fibroblast growth with progressive intimal and medial thickening and narrowing of the vascular lumen (Schoen, 2005) .
TextSentencer_T96 14656-14898 Sentence denotes Prolonged inflammatory vascular injury stimulates proliferation of smooth muscle cells, deposits of extracellular matrix and fibroblast growth with progressive intimal and medial thickening and narrowing of the vascular lumen (Schoen, 2005) .
TextSentencer_T96 14656-14898 Sentence denotes Prolonged inflammatory vascular injury stimulates proliferation of smooth muscle cells, deposits of extracellular matrix and fibroblast growth with progressive intimal and medial thickening and narrowing of the vascular lumen (Schoen, 2005) .
TextSentencer_T97 14899-15131 Sentence denotes In cats, severe systemic vasculitis involving the CNS is frequently caused by FIP coronavirus, but these lesions differ from those observed in the present cat and there was no evidence of coronavirus antigen in the tissues examined.
TextSentencer_T97 14899-15131 Sentence denotes In cats, severe systemic vasculitis involving the CNS is frequently caused by FIP coronavirus, but these lesions differ from those observed in the present cat and there was no evidence of coronavirus antigen in the tissues examined.
TextSentencer_T97 14899-15131 Sentence denotes In cats, severe systemic vasculitis involving the CNS is frequently caused by FIP coronavirus, but these lesions differ from those observed in the present cat and there was no evidence of coronavirus antigen in the tissues examined.
TextSentencer_T98 15132-15189 Sentence denotes Pyogranulomatous vasculitis in FIP mainly involves small-
TextSentencer_T98 15132-15189 Sentence denotes Pyogranulomatous vasculitis in FIP mainly involves small-
TextSentencer_T98 15132-15189 Sentence denotes Pyogranulomatous vasculitis in FIP mainly involves small-
TextSentencer_T99 15191-15331 Sentence denotes and medium-sized veins and inflammatory cells are mainly monocytes/macrophages with a few neutrophils and lymphocytes (Kipar et al., 2005) .
TextSentencer_T99 15191-15331 Sentence denotes and medium-sized veins and inflammatory cells are mainly monocytes/macrophages with a few neutrophils and lymphocytes (Kipar et al., 2005) .
TextSentencer_T99 15191-15331 Sentence denotes and medium-sized veins and inflammatory cells are mainly monocytes/macrophages with a few neutrophils and lymphocytes (Kipar et al., 2005) .
TextSentencer_T100 15332-15490 Sentence denotes The clinical signs of neurological, cardiac and renal dysfunction shown by the present cat were a consequence of vascular damage and related vascular hypoxia.
TextSentencer_T100 15332-15490 Sentence denotes The clinical signs of neurological, cardiac and renal dysfunction shown by the present cat were a consequence of vascular damage and related vascular hypoxia.
TextSentencer_T100 15332-15490 Sentence denotes The clinical signs of neurological, cardiac and renal dysfunction shown by the present cat were a consequence of vascular damage and related vascular hypoxia.
TextSentencer_T101 15491-15724 Sentence denotes Left ventricular concentric hypertrophy with heterogeneous echogenicity of the myocardium was assumed to be a consequence of chronic systemic hypertension, severe vascular inflammatory lesions and myocardial fibrosis (Abbott, 2010) .
TextSentencer_T101 15491-15724 Sentence denotes Left ventricular concentric hypertrophy with heterogeneous echogenicity of the myocardium was assumed to be a consequence of chronic systemic hypertension, severe vascular inflammatory lesions and myocardial fibrosis (Abbott, 2010) .
TextSentencer_T101 15491-15724 Sentence denotes Left ventricular concentric hypertrophy with heterogeneous echogenicity of the myocardium was assumed to be a consequence of chronic systemic hypertension, severe vascular inflammatory lesions and myocardial fibrosis (Abbott, 2010) .
TextSentencer_T102 15725-16066 Sentence denotes Although PAN involving the coronary arteries, with subsequent myocardial infarction, has been described in man and dogs (Carpenter et al., 1988; Odhav et al., 1994; Yuce et al., 2011) , no clinical signs of acute coronary syndrome were identified, and no haemorrhages or infarcts were detected on post-mortem examination in the present case.
TextSentencer_T102 15725-16066 Sentence denotes Although PAN involving the coronary arteries, with subsequent myocardial infarction, has been described in man and dogs (Carpenter et al., 1988; Odhav et al., 1994; Yuce et al., 2011) , no clinical signs of acute coronary syndrome were identified, and no haemorrhages or infarcts were detected on post-mortem examination in the present case.
TextSentencer_T102 15725-16066 Sentence denotes Although PAN involving the coronary arteries, with subsequent myocardial infarction, has been described in man and dogs (Carpenter et al., 1988; Odhav et al., 1994; Yuce et al., 2011) , no clinical signs of acute coronary syndrome were identified, and no haemorrhages or infarcts were detected on post-mortem examination in the present case.
TextSentencer_T103 16067-16305 Sentence denotes Central neurological signs, such as circling and seizures, were likely due to involvement of the meningeal vessels and the presence of cerebral infarction as described in sows and dogs with PAN (Carpenter et al., 1988; Liu et al., 2005) .
TextSentencer_T103 16067-16305 Sentence denotes Central neurological signs, such as circling and seizures, were likely due to involvement of the meningeal vessels and the presence of cerebral infarction as described in sows and dogs with PAN (Carpenter et al., 1988; Liu et al., 2005) .
TextSentencer_T103 16067-16305 Sentence denotes Central neurological signs, such as circling and seizures, were likely due to involvement of the meningeal vessels and the presence of cerebral infarction as described in sows and dogs with PAN (Carpenter et al., 1988; Liu et al., 2005) .
TextSentencer_T104 16306-16399 Sentence denotes The present cat also showed hindlimb paralysis subsequent to necrotizing vascular neuropathy.
TextSentencer_T104 16306-16399 Sentence denotes The present cat also showed hindlimb paralysis subsequent to necrotizing vascular neuropathy.
TextSentencer_T104 16306-16399 Sentence denotes The present cat also showed hindlimb paralysis subsequent to necrotizing vascular neuropathy.
TextSentencer_T105 16400-16491 Sentence denotes Nerve fibre degeneration was secondary to ischaemia due to vasculitis of the vasa nervorum.
TextSentencer_T105 16400-16491 Sentence denotes Nerve fibre degeneration was secondary to ischaemia due to vasculitis of the vasa nervorum.
TextSentencer_T105 16400-16491 Sentence denotes Nerve fibre degeneration was secondary to ischaemia due to vasculitis of the vasa nervorum.
TextSentencer_T106 16492-16835 Sentence denotes In cats, hindlimb paralysis with decreased peripheral pulse pressure, pallor and coolness frequently results from aortic thromboembolism secondary to underlying cardiac disease, most commonly hypertrophic cardiomyopathy, but has also been observed in peripheral arterial neoplasia or foreign body embolization (Dickinson and LeCouteur, 2004) .
TextSentencer_T106 16492-16835 Sentence denotes In cats, hindlimb paralysis with decreased peripheral pulse pressure, pallor and coolness frequently results from aortic thromboembolism secondary to underlying cardiac disease, most commonly hypertrophic cardiomyopathy, but has also been observed in peripheral arterial neoplasia or foreign body embolization (Dickinson and LeCouteur, 2004) .
TextSentencer_T106 16492-16835 Sentence denotes In cats, hindlimb paralysis with decreased peripheral pulse pressure, pallor and coolness frequently results from aortic thromboembolism secondary to underlying cardiac disease, most commonly hypertrophic cardiomyopathy, but has also been observed in peripheral arterial neoplasia or foreign body embolization (Dickinson and LeCouteur, 2004) .
TextSentencer_T107 16836-16994 Sentence denotes Necrotizing vascular neuropathies secondary to PAN are common in man (Imboden, 2017; James et al., 2018) , but have not been described in veterinary medicine.
TextSentencer_T107 16836-16994 Sentence denotes Necrotizing vascular neuropathies secondary to PAN are common in man (Imboden, 2017; James et al., 2018) , but have not been described in veterinary medicine.
TextSentencer_T107 16836-16994 Sentence denotes Necrotizing vascular neuropathies secondary to PAN are common in man (Imboden, 2017; James et al., 2018) , but have not been described in veterinary medicine.
TextSentencer_T108 16995-17172 Sentence denotes Peripheral nerve involvement was associated with neurogenic muscle atrophy and primary myopathic findings, such as perifascicular atrophy, were suggestive of ischaemic myopathy.
TextSentencer_T108 16995-17172 Sentence denotes Peripheral nerve involvement was associated with neurogenic muscle atrophy and primary myopathic findings, such as perifascicular atrophy, were suggestive of ischaemic myopathy.
TextSentencer_T108 16995-17172 Sentence denotes Peripheral nerve involvement was associated with neurogenic muscle atrophy and primary myopathic findings, such as perifascicular atrophy, were suggestive of ischaemic myopathy.
TextSentencer_T109 17173-17294 Sentence denotes In conclusion, PAN should be included in the differential diagnoses of cardiovascular and neurological syndromes in cats.
TextSentencer_T109 17173-17294 Sentence denotes In conclusion, PAN should be included in the differential diagnoses of cardiovascular and neurological syndromes in cats.
TextSentencer_T109 17173-17294 Sentence denotes In conclusion, PAN should be included in the differential diagnoses of cardiovascular and neurological syndromes in cats.
TextSentencer_T110 17295-17395 Sentence denotes Combined muscle and nerve biopsy could provide useful clues for ante-mortem diagnosis of feline PAN.
TextSentencer_T110 17295-17395 Sentence denotes Combined muscle and nerve biopsy could provide useful clues for ante-mortem diagnosis of feline PAN.
TextSentencer_T110 17295-17395 Sentence denotes Combined muscle and nerve biopsy could provide useful clues for ante-mortem diagnosis of feline PAN.