| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1279 |
1707-1711 |
Protein |
denotes |
p100 |
| T1283 |
1715-1721 |
Protein |
denotes |
NF-κB2 |
| T1284 |
1723-1727 |
Protein |
denotes |
p105 |
| T1285 |
1731-1737 |
Protein |
denotes |
NF-κB1 |
| T1286 |
1739-1742 |
Protein |
denotes |
p65 |
| T1287 |
1746-1750 |
Protein |
denotes |
RelA |
| T1288 |
1752-1756 |
Protein |
denotes |
RelB |
| T1289 |
1758-1763 |
Protein |
denotes |
c-Rel |
| T1299 |
1823-1831 |
Regulation |
denotes |
regulate |
| T1298 |
1836-1846 |
Gene_expression |
denotes |
expression |
| T1290 |
1884-1887 |
Protein |
denotes |
TNF |
| T1280 |
1895-1899 |
Protein |
denotes |
IL-6 |
| T1281 |
1901-1918 |
Protein |
denotes |
cyclo-oxygenase-2 |
| T1282 |
1932-1963 |
Protein |
denotes |
inducible nitric oxide synthase |
| T1291 |
2035-2038 |
Protein |
denotes |
TNF |
| T1292 |
2654-2688 |
Protein |
denotes |
receptor activator of NF-κB ligand |
| T1293 |
2690-2695 |
Protein |
denotes |
RANKL |
| T1294 |
2940-2944 |
Protein |
denotes |
CD40 |
| T1295 |
2946-2951 |
Protein |
denotes |
TRAF1 |
| T1296 |
2953-2960 |
Protein |
denotes |
TNFAIP3 |
| T1297 |
2966-2971 |
Protein |
denotes |
c-REL |
| T3288 |
3316-3319 |
Protein |
denotes |
TNF |
| T3289 |
3375-3378 |
Protein |
denotes |
TNF |
| T3290 |
3450-3453 |
Protein |
denotes |
TNF |
| T3291 |
3664-3691 |
Protein |
denotes |
receptor activator of NF-κB |
| T3292 |
3693-3697 |
Protein |
denotes |
RANK |
| T3293 |
3789-3793 |
Protein |
denotes |
RANK |
| T3294 |
3903-3907 |
Protein |
denotes |
CD40 |
| T3295 |
3919-3945 |
Protein |
denotes |
TNF receptor family member |
| T3319 |
3967-3976 |
Gene_expression |
denotes |
expressed |
| T3318 |
4146-4157 |
Positive_regulation |
denotes |
upregulated |
| T3296 |
4197-4200 |
Protein |
denotes |
TNF |
| T3320 |
4207-4214 |
Binding |
denotes |
Binding |
| T3297 |
4222-4233 |
Protein |
denotes |
CD40 ligand |
| T3298 |
4235-4240 |
Protein |
denotes |
CD154 |
| T3321 |
4264-4273 |
Gene_expression |
denotes |
expressed |
| T3299 |
4302-4305 |
Protein |
denotes |
CD4 |
| T3300 |
4576-4580 |
Protein |
denotes |
CD40 |
| T3323 |
4756-4764 |
Positive_regulation |
denotes |
Enhanced |
| T3322 |
4765-4775 |
Gene_expression |
denotes |
expression |
| T3301 |
4810-4834 |
Protein |
denotes |
B-cell activating factor |
| T3302 |
4836-4840 |
Protein |
denotes |
BAFF |
| T3303 |
4957-4961 |
Protein |
denotes |
BAFF |
| T3304 |
5011-5033 |
Protein |
denotes |
lymphotoxin β receptor |
| T3305 |
5880-5925 |
Protein |
denotes |
High mobility group box chromosomal protein 1 |
| T3306 |
5927-5932 |
Protein |
denotes |
HMGB1 |
| T3307 |
5954-5973 |
Protein |
denotes |
chromatin component |
| T3324 |
5995-6003 |
Localization |
denotes |
secreted |
| T3325 |
6032-6040 |
Localization |
denotes |
released |
| T3308 |
6099-6111 |
Protein |
denotes |
TLR4 ligands |
| T3309 |
6138-6143 |
Protein |
denotes |
HMGB1 |
| T3326 |
6147-6156 |
Positive_regulation |
denotes |
increased |
| T3310 |
6183-6188 |
Protein |
denotes |
HMGB1 |
| T3311 |
6248-6253 |
Protein |
denotes |
HMGB1 |
| T3312 |
6311-6336 |
Protein |
denotes |
Myeloid-related protein 8 |
| T3313 |
6341-6367 |
Protein |
denotes |
myeloid-related protein 14 |
| T3314 |
6565-6569 |
Protein |
denotes |
TLR4 |
| T3327 |
6570-6577 |
Positive_regulation |
denotes |
induced |
| T3315 |
6736-6747 |
Protein |
denotes |
fibronectin |
| T3316 |
6749-6757 |
Protein |
denotes |
biglycan |
| T3317 |
6759-6769 |
Protein |
denotes |
tenascin C |
| T6942 |
7259-7263 |
Protein |
denotes |
IκBα |
| T6943 |
7265-7269 |
Protein |
denotes |
IκBβ |
| T6944 |
7271-7275 |
Protein |
denotes |
IκBε |
| T6945 |
7277-7281 |
Protein |
denotes |
p105 |
| T6946 |
7297-7303 |
Protein |
denotes |
NF-κB1 |
| T6947 |
7306-7310 |
Protein |
denotes |
p100 |
| T6948 |
7326-7332 |
Protein |
denotes |
NF-κB2 |
| T6949 |
7365-7369 |
Protein |
denotes |
IκBξ |
| T6950 |
7374-7379 |
Protein |
denotes |
Bcl-3 |
| T6951 |
7437-7441 |
Protein |
denotes |
p100 |
| T6952 |
7446-7450 |
Protein |
denotes |
p105 |
| T6953 |
7473-7476 |
Protein |
denotes |
p52 |
| T6954 |
7481-7484 |
Protein |
denotes |
p50 |
| T6955 |
7808-7811 |
Protein |
denotes |
TNF |
| T6956 |
7830-7835 |
Protein |
denotes |
RANKL |
| T6957 |
8275-8279 |
Protein |
denotes |
IKK1 |
| T6958 |
8284-8288 |
Protein |
denotes |
IKK2 |
| T6959 |
8304-8308 |
Protein |
denotes |
IKKα |
| T6960 |
8313-8317 |
Protein |
denotes |
IKKβ |
| T6961 |
8346-8371 |
Protein |
denotes |
NF-κB essential modulator |
| T6962 |
8373-8377 |
Protein |
denotes |
NEMO |
| T6963 |
8394-8398 |
Protein |
denotes |
IKKγ |
| T6964 |
8451-8455 |
Protein |
denotes |
IKK2 |
| T6965 |
8460-8464 |
Protein |
denotes |
NEMO |
| T6966 |
8474-8478 |
Protein |
denotes |
IKK1 |
| T7053 |
8484-8492 |
Positive_regulation |
denotes |
required |
| T20647 |
8599-8609 |
Binding |
denotes |
engagement |
| T20590 |
8649-8654 |
Protein |
denotes |
TNFR1 |
| T20599 |
8656-8660 |
Protein |
denotes |
CD40 |
| T20600 |
8662-8666 |
Protein |
denotes |
RANK |
| T20601 |
8672-8676 |
Protein |
denotes |
TLR4 |
| T20646 |
8689-8700 |
Binding |
denotes |
recruitment |
| T20602 |
8731-8777 |
Protein |
denotes |
TNF receptor 1-associated death domain protein |
| T20603 |
8779-8784 |
Protein |
denotes |
TRADD |
| T20604 |
8787-8792 |
Protein |
denotes |
MyD88 |
| T20605 |
8794-8797 |
Protein |
denotes |
MAL |
| T20606 |
8799-8842 |
Protein |
denotes |
TIR domain-containing adaptor-inducing IFNβ |
| T20591 |
8844-8848 |
Protein |
denotes |
TRIF |
| T20592 |
8861-8865 |
Protein |
denotes |
RIP1 |
| T20593 |
8867-8872 |
Protein |
denotes |
IRAK1 |
| T20594 |
8874-8879 |
Protein |
denotes |
IRAK4 |
| T20595 |
8905-8910 |
Protein |
denotes |
TRAF2 |
| T20596 |
8912-8917 |
Protein |
denotes |
TRAF6 |
| T20597 |
8919-8924 |
Protein |
denotes |
cIAP1 |
| T20598 |
8926-8931 |
Protein |
denotes |
cIAP2 |
| T20649 |
8961-8979 |
Positive_regulation |
denotes |
polyubiquitination |
| T20607 |
8990-8994 |
Protein |
denotes |
RIP1 |
| T20608 |
8999-9004 |
Protein |
denotes |
IRAK1 |
| T20609 |
9023-9027 |
Protein |
denotes |
NEMO |
| T20648 |
9046-9055 |
Positive_regulation |
denotes |
resulting |
| T20650 |
9063-9074 |
Binding |
denotes |
recruitment |
| T20610 |
9106-9110 |
Protein |
denotes |
IKK2 |
| T20611 |
9115-9119 |
Protein |
denotes |
TAK1 |
| T20612 |
9121-9125 |
Protein |
denotes |
TAK1 |
| T20651 |
9131-9145 |
Phosphorylation |
denotes |
phosphorylates |
| T20652 |
9150-9159 |
Positive_regulation |
denotes |
activates |
| T20613 |
9160-9164 |
Protein |
denotes |
IKK2 |
| T20653 |
9180-9194 |
Phosphorylation |
denotes |
phosphorylates |
| T20614 |
9195-9199 |
Protein |
denotes |
IκBα |
| T20615 |
9321-9324 |
Protein |
denotes |
p65 |
| T20616 |
9329-9332 |
Protein |
denotes |
p50 |
| T20617 |
9400-9405 |
Protein |
denotes |
TRAF1 |
| T20618 |
9534-9537 |
Protein |
denotes |
A20 |
| T20619 |
9542-9546 |
Protein |
denotes |
CYLD |
| T20654 |
9609-9618 |
Binding |
denotes |
targeting |
| T20620 |
9658-9662 |
Protein |
denotes |
RIP1 |
| T20621 |
9667-9672 |
Protein |
denotes |
TRAF6 |
| T20622 |
9760-9766 |
Protein |
denotes |
ABIN-1 |
| T20623 |
9771-9774 |
Protein |
denotes |
p62 |
| T20655 |
9836-9846 |
Negative_regulation |
denotes |
inhibiting |
| T20656 |
9847-9857 |
Gene_expression |
denotes |
expression |
| T20624 |
9861-9866 |
Protein |
denotes |
IRAK1 |
| T20625 |
9871-9876 |
Protein |
denotes |
TRAF6 |
| T20659 |
9914-9923 |
Negative_regulation |
denotes |
inhibited |
| T20626 |
9953-9959 |
Protein |
denotes |
SIGIRR |
| T20657 |
9988-9995 |
Negative_regulation |
denotes |
compete |
| T20627 |
10001-10005 |
Protein |
denotes |
TLR4 |
| T20658 |
10010-10017 |
Binding |
denotes |
binding |
| T20628 |
10021-10026 |
Protein |
denotes |
IRAK1 |
| T20629 |
10031-10036 |
Protein |
denotes |
TRAF6 |
| T20630 |
10194-10198 |
Protein |
denotes |
ABIN |
| T20631 |
10200-10230 |
Protein |
denotes |
A20-binding inhibitor of NF-κB |
| T20632 |
10271-10275 |
Protein |
denotes |
CYLD |
| T20633 |
10277-10292 |
Protein |
denotes |
cylindromatosis |
| T20634 |
10367-10372 |
Protein |
denotes |
MyD88 |
| T20635 |
10374-10422 |
Protein |
denotes |
myeloid differentiation primary response gene 88 |
| T20636 |
10424-10428 |
Protein |
denotes |
NEMO |
| T20637 |
10430-10455 |
Protein |
denotes |
NF-κB essential modulator |
| T20638 |
10477-10481 |
Protein |
denotes |
RANK |
| T20639 |
10483-10510 |
Protein |
denotes |
receptor activator of NF-κB |
| T20640 |
10512-10516 |
Protein |
denotes |
RIP1 |
| T20641 |
10518-10548 |
Protein |
denotes |
receptor interacting protein 1 |
| T20642 |
10550-10556 |
Protein |
denotes |
SIGIRR |
| T20643 |
10558-10600 |
Protein |
denotes |
single-immunoglobulinIL-1 receptor-related |
| T20644 |
10696-10699 |
Protein |
denotes |
TNF |
| T20645 |
10701-10723 |
Protein |
denotes |
tumour necrosis factor |
| T6967 |
10782-10785 |
Protein |
denotes |
TNF |
| T6968 |
10795-10798 |
Protein |
denotes |
TNF |
| T7054 |
10826-10837 |
Binding |
denotes |
recruitment |
| T6969 |
10841-10879 |
Protein |
denotes |
TNF receptor-1-associated death domain |
| T6970 |
10881-10886 |
Protein |
denotes |
TRADD |
| T6971 |
10903-10933 |
Protein |
denotes |
receptor interacting protein 1 |
| T6972 |
10935-10939 |
Protein |
denotes |
RIP1 |
| T6973 |
11006-11045 |
Protein |
denotes |
TNF receptor-associated factor (TRAF) 2 |
| T6974 |
11050-11055 |
Protein |
denotes |
TRAF5 |
| T7055 |
11071-11075 |
Binding |
denotes |
bind |
| T6975 |
11101-11141 |
Protein |
denotes |
cellular inhibitor of apoptosis (cIAP) 1 |
| T6976 |
11146-11151 |
Protein |
denotes |
cIAP2 |
| T6977 |
11167-11170 |
Protein |
denotes |
TNF |
| T7056 |
11197-11202 |
Binding |
denotes |
bound |
| T6978 |
11203-11207 |
Protein |
denotes |
RIP1 |
| T6979 |
11264-11269 |
Protein |
denotes |
TRAF2 |
| T6980 |
11270-11271 |
Protein |
denotes |
5 |
| T6981 |
11276-11281 |
Protein |
denotes |
cIAP1 |
| T6982 |
11282-11283 |
Protein |
denotes |
2 |
| T6983 |
11308-11312 |
Protein |
denotes |
RIP1 |
| T7057 |
11313-11327 |
Binding |
denotes |
ubiquitination |
| T6984 |
11405-11409 |
Protein |
denotes |
RIP1 |
| T7058 |
11447-11454 |
Binding |
denotes |
recruit |
| T6985 |
11467-11471 |
Protein |
denotes |
TAK1 |
| T6986 |
11515-11519 |
Protein |
denotes |
NEMO |
| T6987 |
11524-11528 |
Protein |
denotes |
TAB1 |
| T6988 |
11529-11530 |
Protein |
denotes |
2 |
| T7059 |
11612-11620 |
Regulation |
denotes |
modifies |
| T6989 |
11621-11625 |
Protein |
denotes |
NEMO |
| T6990 |
11680-11683 |
Protein |
denotes |
TNF |
| T6991 |
11906-11910 |
Protein |
denotes |
TAK1 |
| T6992 |
11994-11998 |
Protein |
denotes |
TLR4 |
| T7063 |
11999-12010 |
Positive_regulation |
denotes |
stimulation |
| T7061 |
12033-12040 |
Positive_regulation |
denotes |
induces |
| T7060 |
12045-12056 |
Binding |
denotes |
recruitment |
| T6993 |
12060-12094 |
Protein |
denotes |
Toll/IL-1 receptor adaptor protein |
| T6994 |
12116-12118 |
Protein |
denotes |
Ma |
| T6995 |
12125-12154 |
Protein |
denotes |
TRIF-related adaptor molecule |
| T6996 |
12156-12160 |
Protein |
denotes |
TRAM |
| T7062 |
12212-12219 |
Binding |
denotes |
recruit |
| T6997 |
12220-12268 |
Protein |
denotes |
myeloid differentiation primary response gene 88 |
| T6998 |
12270-12275 |
Protein |
denotes |
MyD88 |
| T6999 |
12281-12324 |
Protein |
denotes |
TIR domain-containing adaptor-inducing IFNβ |
| T7000 |
12326-12330 |
Protein |
denotes |
TRIF |
| T7001 |
12347-12352 |
Protein |
denotes |
MyD88 |
| T7002 |
12427-12432 |
Protein |
denotes |
TRAF6 |
| T7003 |
12487-12492 |
Protein |
denotes |
TRAF6 |
| T7004 |
12499-12503 |
Protein |
denotes |
TRIF |
| T7065 |
12509-12517 |
Binding |
denotes |
recruits |
| T7005 |
12518-12523 |
Protein |
denotes |
TRAF6 |
| T7006 |
12533-12537 |
Protein |
denotes |
RIP1 |
| T7064 |
12556-12567 |
Binding |
denotes |
interaction |
| T7066 |
12588-12596 |
Positive_regulation |
denotes |
activate |
| T7007 |
12597-12601 |
Protein |
denotes |
TAK1 |
| T7008 |
12662-12665 |
Protein |
denotes |
TNF |
| T7009 |
12741-12763 |
Protein |
denotes |
lymphotoxin β receptor |
| T7010 |
12765-12778 |
Protein |
denotes |
BAFF receptor |
| T7011 |
12780-12784 |
Protein |
denotes |
CD40 |
| T7012 |
12790-12794 |
Protein |
denotes |
RANK |
| T7013 |
12824-12828 |
Protein |
denotes |
p100 |
| T7014 |
12863-12866 |
Protein |
denotes |
p52 |
| T7015 |
12892-12896 |
Protein |
denotes |
RelB |
| T7016 |
13107-13111 |
Protein |
denotes |
IKK1 |
| T7067 |
13122-13131 |
Positive_regulation |
denotes |
activated |
| T7017 |
13156-13177 |
Protein |
denotes |
NF-κB inducing kinase |
| T7018 |
13179-13182 |
Protein |
denotes |
NIK |
| T7019 |
13185-13188 |
Protein |
denotes |
NIK |
| T7068 |
13206-13215 |
Regulation |
denotes |
regulated |
| T7021 |
13330-13333 |
Protein |
denotes |
NIK |
| T7022 |
13371-13376 |
Protein |
denotes |
TRAF2 |
| T7023 |
13378-13383 |
Protein |
denotes |
TRAF3 |
| T7024 |
13389-13394 |
Protein |
denotes |
cIAP1 |
| T7025 |
13395-13396 |
Protein |
denotes |
2 |
| T7020 |
13426-13429 |
Protein |
denotes |
NIK |
| T7069 |
13457-13468 |
Protein_catabolism |
denotes |
degradation |
| T7074 |
13533-13539 |
Negative_regulation |
denotes |
remove |
| T7026 |
13540-13545 |
Protein |
denotes |
TRAF3 |
| T7073 |
13567-13577 |
Binding |
denotes |
recruiting |
| T7072 |
13610-13617 |
Binding |
denotes |
attract |
| T7027 |
13618-13623 |
Protein |
denotes |
TRAF2 |
| T7028 |
13628-13633 |
Protein |
denotes |
cIAP1 |
| T7029 |
13634-13635 |
Protein |
denotes |
2 |
| T7071 |
13647-13656 |
Positive_regulation |
denotes |
essential |
| T7030 |
13672-13677 |
Protein |
denotes |
TRAF3 |
| T7070 |
13678-13689 |
Protein_catabolism |
denotes |
degradation |
| T7075 |
13715-13724 |
Negative_regulation |
denotes |
releasing |
| T7031 |
13725-13728 |
Protein |
denotes |
NIK |
| T7077 |
13751-13762 |
Protein_catabolism |
denotes |
degradation |
| T7076 |
13764-13773 |
Positive_regulation |
denotes |
resulting |
| T7032 |
13777-13780 |
Protein |
denotes |
NIK |
| T7078 |
13781-13793 |
Positive_regulation |
denotes |
accumulation |
| T7033 |
13798-13802 |
Protein |
denotes |
IKK1 |
| T7079 |
13803-13818 |
Phosphorylation |
denotes |
phosphorylation |
| T22107 |
13880-13884 |
Protein |
denotes |
CD40 |
| T22108 |
13889-13893 |
Protein |
denotes |
RANK |
| T22141 |
13946-13955 |
Regulation |
denotes |
dependent |
| T22109 |
13959-13980 |
Protein |
denotes |
NF-κB inducing kinase |
| T22110 |
13982-13985 |
Protein |
denotes |
NIK |
| T22142 |
13987-13997 |
Gene_expression |
denotes |
expression |
| T22113 |
14028-14031 |
Protein |
denotes |
NIK |
| T22114 |
14085-14090 |
Protein |
denotes |
TRAF2 |
| T22115 |
14092-14097 |
Protein |
denotes |
TRAF3 |
| T22116 |
14102-14107 |
Protein |
denotes |
cIAP1 |
| T22117 |
14108-14109 |
Protein |
denotes |
2 |
| T22143 |
14144-14162 |
Binding |
denotes |
polyubiquitination |
| T22144 |
14179-14190 |
Protein_catabolism |
denotes |
degradation |
| T22111 |
14194-14197 |
Protein |
denotes |
NIK |
| T22112 |
14207-14210 |
Protein |
denotes |
NIK |
| T22118 |
14244-14249 |
Protein |
denotes |
TRAF3 |
| T22145 |
14253-14262 |
Binding |
denotes |
recruited |
| T22119 |
14286-14291 |
Protein |
denotes |
TRAF2 |
| T22147 |
14326-14344 |
Binding |
denotes |
polyubiquitination |
| T22120 |
14348-14353 |
Protein |
denotes |
cIAP1 |
| T22121 |
14354-14355 |
Protein |
denotes |
2 |
| T22146 |
14376-14386 |
Positive_regulation |
denotes |
activation |
| T22122 |
14401-14406 |
Protein |
denotes |
cIAP1 |
| T22123 |
14407-14408 |
Protein |
denotes |
2 |
| T22148 |
14432-14450 |
Binding |
denotes |
polyubiquitination |
| T22124 |
14454-14459 |
Protein |
denotes |
TRAF3 |
| T22125 |
14473-14476 |
Protein |
denotes |
NIK |
| T22126 |
14491-14496 |
Protein |
denotes |
TRAF3 |
| T22149 |
14500-14508 |
Protein_catabolism |
denotes |
degraded |
| T22127 |
14513-14516 |
Protein |
denotes |
NIK |
| T22150 |
14545-14554 |
Positive_regulation |
denotes |
increased |
| T22128 |
14555-14558 |
Protein |
denotes |
NIK |
| T22129 |
14579-14582 |
Protein |
denotes |
NIK |
| T22153 |
14588-14602 |
Phosphorylation |
denotes |
phosphorylates |
| T22154 |
14607-14616 |
Positive_regulation |
denotes |
activates |
| T22130 |
14617-14621 |
Protein |
denotes |
IKK1 |
| T22151 |
14629-14637 |
Positive_regulation |
denotes |
mediates |
| T22131 |
14644-14648 |
Protein |
denotes |
p100 |
| T22152 |
14649-14664 |
Phosphorylation |
denotes |
phosphorylation |
| T22155 |
14740-14751 |
Protein_catabolism |
denotes |
degradation |
| T22132 |
14755-14759 |
Protein |
denotes |
p100 |
| T22133 |
14763-14766 |
Protein |
denotes |
p52 |
| T22134 |
14799-14803 |
Protein |
denotes |
RelB |
| T22135 |
14839-14844 |
Protein |
denotes |
TRAF3 |
| T22136 |
14846-14851 |
Protein |
denotes |
TRAF1 |
| T22137 |
15065-15069 |
Protein |
denotes |
RANK |
| T22138 |
15071-15098 |
Protein |
denotes |
receptor activator of NF-κB |
| T22139 |
15138-15141 |
Protein |
denotes |
TNF |
| T22140 |
15143-15165 |
Protein |
denotes |
tumour necrosis factor |
| T7034 |
15195-15199 |
Protein |
denotes |
CD40 |
| T7035 |
15201-15223 |
Protein |
denotes |
lymphotoxin β receptor |
| T7036 |
15228-15232 |
Protein |
denotes |
RANK |
| T7037 |
15348-15352 |
Protein |
denotes |
CD40 |
| T7038 |
15357-15361 |
Protein |
denotes |
RANK |
| T7080 |
15362-15370 |
Binding |
denotes |
interact |
| T7039 |
15408-15413 |
Protein |
denotes |
TRAF1 |
| T7040 |
15415-15420 |
Protein |
denotes |
TRAF2 |
| T7041 |
15422-15427 |
Protein |
denotes |
TRAF3 |
| T7042 |
15429-15434 |
Protein |
denotes |
TRAF5 |
| T7043 |
15440-15445 |
Protein |
denotes |
TRAF6 |
| T7044 |
15489-15494 |
Protein |
denotes |
TRAF2 |
| T7045 |
15499-15504 |
Protein |
denotes |
TRAF3 |
| T7046 |
15676-15680 |
Protein |
denotes |
CD40 |
| T7047 |
15725-15730 |
Protein |
denotes |
TRAF6 |
| T7081 |
15734-15742 |
Positive_regulation |
denotes |
required |
| T7048 |
15747-15751 |
Protein |
denotes |
CD40 |
| T7049 |
15780-15784 |
Protein |
denotes |
IL-6 |
| T7082 |
15785-15795 |
Gene_expression |
denotes |
production |
| T7050 |
15803-15808 |
Protein |
denotes |
TRAF2 |
| T7083 |
15812-15820 |
Positive_regulation |
denotes |
required |
| T7051 |
15850-15855 |
Protein |
denotes |
TRAF3 |
| T7052 |
15890-15894 |
Protein |
denotes |
CD40 |
| T9128 |
16895-16901 |
Protein |
denotes |
MyD88s |
| T9129 |
16903-16909 |
Protein |
denotes |
IRAK-M |
| T9130 |
16915-16921 |
Protein |
denotes |
TOLLIP |
| T9131 |
17069-17073 |
Protein |
denotes |
IKK1 |
| T9132 |
17297-17301 |
Protein |
denotes |
IKK1 |
| T9145 |
17302-17311 |
Negative_regulation |
denotes |
deficient |
| T9141 |
17333-17343 |
Gene_expression |
denotes |
expressing |
| T9133 |
17353-17357 |
Protein |
denotes |
IKK1 |
| T9144 |
17418-17424 |
Positive_regulation |
denotes |
result |
| T9146 |
17428-17436 |
Positive_regulation |
denotes |
enhanced |
| T9134 |
17437-17441 |
Protein |
denotes |
IKK2 |
| T9142 |
17442-17452 |
Positive_regulation |
denotes |
activation |
| T9135 |
17457-17461 |
Protein |
denotes |
IκBα |
| T9143 |
17462-17473 |
Protein_catabolism |
denotes |
degradation |
| T9137 |
17480-17484 |
Protein |
denotes |
IKK1 |
| T9147 |
17580-17595 |
Phosphorylation |
denotes |
phosphorylating |
| T9136 |
17596-17601 |
Protein |
denotes |
STAT1 |
| T9138 |
17660-17664 |
Protein |
denotes |
IKK1 |
| T9148 |
17665-17679 |
Phosphorylation |
denotes |
phosphorylates |
| T9139 |
17680-17683 |
Protein |
denotes |
NIK |
| T9140 |
17781-17785 |
Protein |
denotes |
IKK1 |
| T11744 |
17941-17944 |
Protein |
denotes |
A20 |
| T11745 |
17953-17956 |
Protein |
denotes |
A20 |
| T11746 |
17972-17979 |
Protein |
denotes |
TNFAIP3 |
| T11747 |
17986-18011 |
Protein |
denotes |
ubiquitin-editing protein |
| T11748 |
18038-18043 |
Protein |
denotes |
NF-κB |
| T11749 |
18132-18135 |
Protein |
denotes |
TNF |
| T11752 |
18275-18278 |
Protein |
denotes |
A20 |
| T11753 |
18382-18386 |
Protein |
denotes |
RIP1 |
| T11754 |
18388-18392 |
Protein |
denotes |
RIP2 |
| T11750 |
18394-18399 |
Protein |
denotes |
TRAF6 |
| T11751 |
18404-18409 |
Protein |
denotes |
MALT1 |
| T11806 |
18498-18508 |
Negative_regulation |
denotes |
disruption |
| T11755 |
18567-18572 |
Protein |
denotes |
Ubc13 |
| T11756 |
18577-18583 |
Protein |
denotes |
Ubc5hc |
| T11757 |
18611-18616 |
Protein |
denotes |
TRAF6 |
| T11758 |
18618-18623 |
Protein |
denotes |
TRAF2 |
| T11759 |
18628-18633 |
Protein |
denotes |
cIAP1 |
| T11760 |
18634-18635 |
Protein |
denotes |
2 |
| T11761 |
18691-18694 |
Protein |
denotes |
A20 |
| T11807 |
18738-18749 |
Binding |
denotes |
association |
| T11762 |
18753-18756 |
Protein |
denotes |
A20 |
| T11809 |
18766-18773 |
Regulation |
denotes |
targets |
| T11808 |
18774-18782 |
Positive_regulation |
denotes |
requires |
| T11763 |
18838-18877 |
Protein |
denotes |
A20-binding inhibitor of NF-κB (ABIN) 1 |
| T11764 |
18882-18904 |
Protein |
denotes |
Tax1-binding protein 1 |
| T11765 |
18964-18967 |
Protein |
denotes |
A20 |
| T11810 |
18985-18994 |
Negative_regulation |
denotes |
inhibitor |
| T11766 |
19062-19065 |
Protein |
denotes |
A20 |
| T11767 |
19126-19129 |
Protein |
denotes |
A20 |
| T11811 |
19130-19139 |
Negative_regulation |
denotes |
deficient |
| T11768 |
19311-19314 |
Protein |
denotes |
A20 |
| T11812 |
19315-19324 |
Negative_regulation |
denotes |
deficient |
| T11769 |
19360-19363 |
Protein |
denotes |
TNF |
| T11814 |
19475-19482 |
Negative_regulation |
denotes |
lacking |
| T11770 |
19483-19486 |
Protein |
denotes |
A20 |
| T11771 |
19643-19646 |
Protein |
denotes |
TNF |
| T11813 |
19647-19654 |
Positive_regulation |
denotes |
induced |
| T11772 |
19677-19680 |
Protein |
denotes |
A20 |
| T11815 |
19790-19797 |
Negative_regulation |
denotes |
lacking |
| T11773 |
19798-19801 |
Protein |
denotes |
A20 |
| T11774 |
19929-19932 |
Protein |
denotes |
A20 |
| T11816 |
19933-19943 |
Gene_expression |
denotes |
expression |
| T11775 |
20106-20109 |
Protein |
denotes |
A20 |
| T11817 |
20110-20120 |
Gene_expression |
denotes |
expression |
| T11818 |
20131-20140 |
Regulation |
denotes |
regulated |
| T11776 |
20168-20171 |
Protein |
denotes |
A20 |
| T11777 |
20271-20274 |
Protein |
denotes |
A20 |
| T11819 |
20275-20285 |
Gene_expression |
denotes |
expressing |
| T11778 |
20499-20502 |
Protein |
denotes |
A20 |
| T11821 |
20503-20513 |
Gene_expression |
denotes |
expression |
| T11822 |
20553-20563 |
Negative_regulation |
denotes |
inhibition |
| T11823 |
20586-20595 |
Negative_regulation |
denotes |
decreased |
| T11779 |
20606-20609 |
Protein |
denotes |
TNF |
| T11780 |
20611-20616 |
Protein |
denotes |
IL-1β |
| T11781 |
20618-20622 |
Protein |
denotes |
IL-6 |
| T11782 |
20632-20637 |
Protein |
denotes |
RANKL |
| T11783 |
20639-20674 |
Protein |
denotes |
monocyte chemo-attractant protein 1 |
| T11784 |
20703-20706 |
Protein |
denotes |
A20 |
| T11824 |
20707-20714 |
Positive_regulation |
denotes |
induces |
| T11820 |
20836-20846 |
Gene_expression |
denotes |
expression |
| T11785 |
20861-20864 |
Protein |
denotes |
TNF |
| T11786 |
20869-20874 |
Protein |
denotes |
IL-1β |
| T11825 |
20970-20979 |
Negative_regulation |
denotes |
decreased |
| T11787 |
20996-20999 |
Protein |
denotes |
TNF |
| T11788 |
21004-21009 |
Protein |
denotes |
IL-1β |
| T11789 |
21013-21016 |
Protein |
denotes |
A20 |
| T11790 |
21162-21165 |
Protein |
denotes |
A20 |
| T11826 |
21166-21180 |
Positive_regulation |
denotes |
overexpression |
| T11791 |
21257-21260 |
Protein |
denotes |
A20 |
| T11827 |
21456-21460 |
Negative_regulation |
denotes |
lack |
| T11792 |
21461-21464 |
Protein |
denotes |
A20 |
| T11793 |
21607-21610 |
Protein |
denotes |
A20 |
| T11828 |
21791-21802 |
Binding |
denotes |
association |
| T11794 |
21828-21831 |
Protein |
denotes |
A20 |
| T11829 |
21972-21981 |
Regulation |
denotes |
influence |
| T11795 |
21982-21985 |
Protein |
denotes |
A20 |
| T11796 |
22029-22032 |
Protein |
denotes |
A20 |
| T11797 |
22116-22119 |
Protein |
denotes |
A20 |
| T11831 |
22123-22131 |
Positive_regulation |
denotes |
required |
| T11798 |
22151-22154 |
Protein |
denotes |
TNF |
| T11830 |
22155-22162 |
Positive_regulation |
denotes |
induced |
| T11799 |
22176-22179 |
Protein |
denotes |
TNF |
| T11800 |
22208-22216 |
Protein |
denotes |
cytokine |
| T11801 |
22246-22249 |
Protein |
denotes |
A20 |
| T11802 |
22327-22330 |
Protein |
denotes |
A20 |
| T11803 |
22507-22510 |
Protein |
denotes |
A20 |
| T11833 |
22545-22554 |
Negative_regulation |
denotes |
repressed |
| T11804 |
22555-22558 |
Protein |
denotes |
A20 |
| T11832 |
22559-22572 |
Transcription |
denotes |
transcription |
| T11805 |
22791-22794 |
Protein |
denotes |
A20 |
| T13628 |
22866-22869 |
Protein |
denotes |
A20 |
| T13659 |
22870-22877 |
Binding |
denotes |
binding |
| T13629 |
22898-22904 |
Protein |
denotes |
ABIN-1 |
| T13630 |
22906-22912 |
Protein |
denotes |
ABIN-2 |
| T13631 |
22917-22923 |
Protein |
denotes |
ABIN-3 |
| T13632 |
22939-22945 |
Protein |
denotes |
TNIP-1 |
| T13633 |
22947-22953 |
Protein |
denotes |
TNIP-2 |
| T13634 |
22959-22965 |
Protein |
denotes |
TNIP-3 |
| T13660 |
22999-23008 |
Gene_expression |
denotes |
expressed |
| T13635 |
23009-23012 |
Protein |
denotes |
A20 |
| T13661 |
23013-23024 |
Binding |
denotes |
interacting |
| T13636 |
23080-23083 |
Protein |
denotes |
TNF |
| T13662 |
23229-23235 |
Binding |
denotes |
target |
| T13637 |
23236-23239 |
Protein |
denotes |
A20 |
| T13638 |
23292-23295 |
Protein |
denotes |
A20 |
| T13639 |
23297-23303 |
Protein |
denotes |
ABIN-1 |
| T13640 |
23308-23314 |
Protein |
denotes |
ABIN-3 |
| T13663 |
23315-23325 |
Gene_expression |
denotes |
expression |
| T13641 |
23383-23386 |
Protein |
denotes |
A20 |
| T13642 |
23495-23501 |
Protein |
denotes |
ABIN-1 |
| T13664 |
23502-23511 |
Negative_regulation |
denotes |
deficient |
| T13643 |
23516-23522 |
Protein |
denotes |
ABIN-2 |
| T13665 |
23523-23532 |
Negative_regulation |
denotes |
deficient |
| T13644 |
23707-23713 |
Protein |
denotes |
ABIN-3 |
| T13667 |
23717-23726 |
Gene_expression |
denotes |
expressed |
| T13668 |
23752-23759 |
Gene_expression |
denotes |
express |
| T13645 |
23762-23789 |
Protein |
denotes |
truncated and inactive form |
| T13666 |
23790-23797 |
Negative_regulation |
denotes |
lacking |
| T13646 |
23848-23851 |
Protein |
denotes |
A20 |
| T13647 |
23853-23859 |
Protein |
denotes |
ABIN-1 |
| T13670 |
23874-23882 |
Negative_regulation |
denotes |
inhibits |
| T13648 |
23883-23886 |
Protein |
denotes |
TNF |
| T13671 |
23887-23894 |
Positive_regulation |
denotes |
induced |
| T13649 |
23915-23921 |
Protein |
denotes |
ABIN-1 |
| T13669 |
23922-23931 |
Negative_regulation |
denotes |
deficient |
| T13650 |
23962-23965 |
Protein |
denotes |
TNF |
| T13651 |
24048-24054 |
Protein |
denotes |
ABIN-1 |
| T13652 |
24076-24079 |
Protein |
denotes |
TNF |
| T13672 |
24080-24087 |
Positive_regulation |
denotes |
induced |
| T13653 |
24136-24142 |
Protein |
denotes |
ABIN-1 |
| T13654 |
24217-24223 |
Protein |
denotes |
ABIN-1 |
| T13655 |
24239-24242 |
Protein |
denotes |
A20 |
| T13674 |
24468-24474 |
Regulation |
denotes |
depend |
| T13673 |
24482-24492 |
Gene_expression |
denotes |
expression |
| T13656 |
24526-24532 |
Protein |
denotes |
ABIN-3 |
| T13657 |
24537-24540 |
Protein |
denotes |
A20 |
| T13658 |
24679-24685 |
Protein |
denotes |
ABIN-1 |
| T15029 |
25238-25253 |
Protein |
denotes |
Cylindromatosis |
| T15030 |
25262-25277 |
Protein |
denotes |
Cylindromatosis |
| T15031 |
25279-25283 |
Protein |
denotes |
CYLD |
| T15032 |
25385-25389 |
Protein |
denotes |
CYLD |
| T15037 |
25578-25582 |
Protein |
denotes |
CYLD |
| T15038 |
25588-25611 |
Protein |
denotes |
deubiquitinating enzyme |
| T15039 |
25674-25678 |
Protein |
denotes |
RANK |
| T15040 |
25807-25811 |
Protein |
denotes |
NEMO |
| T15041 |
25813-25818 |
Protein |
denotes |
TRAF2 |
| T15033 |
25820-25825 |
Protein |
denotes |
TRAF6 |
| T15034 |
25827-25832 |
Protein |
denotes |
TRAF7 |
| T15035 |
25834-25838 |
Protein |
denotes |
RIP1 |
| T15036 |
25843-25847 |
Protein |
denotes |
TAK1 |
| T15042 |
25884-25887 |
Protein |
denotes |
A20 |
| T15043 |
25933-25936 |
Protein |
denotes |
A20 |
| T15044 |
25948-25952 |
Protein |
denotes |
CYLD |
| T15045 |
25985-25988 |
Protein |
denotes |
A20 |
| T15063 |
25997-26006 |
Gene_expression |
denotes |
expressed |
| T15046 |
26143-26147 |
Protein |
denotes |
CYLD |
| T15047 |
26290-26294 |
Protein |
denotes |
CYLD |
| T15048 |
26333-26337 |
Protein |
denotes |
RANK |
| T15064 |
26406-26416 |
Negative_regulation |
denotes |
deficiency |
| T15049 |
26420-26424 |
Protein |
denotes |
CYLD |
| T15050 |
26559-26564 |
Protein |
denotes |
RANKL |
| T15065 |
26565-26572 |
Positive_regulation |
denotes |
induced |
| T15051 |
26630-26634 |
Protein |
denotes |
CYLD |
| T15066 |
26635-26645 |
Gene_expression |
denotes |
expression |
| T15069 |
26658-26669 |
Positive_regulation |
denotes |
upregulated |
| T15052 |
26690-26695 |
Protein |
denotes |
RANKL |
| T15068 |
26730-26739 |
Binding |
denotes |
recruited |
| T15053 |
26757-26762 |
Protein |
denotes |
TRAF6 |
| T15054 |
26771-26780 |
Protein |
denotes |
ubiquitin |
| T15070 |
26781-26788 |
Binding |
denotes |
binding |
| T15055 |
26805-26808 |
Protein |
denotes |
p62 |
| T15056 |
26824-26838 |
Protein |
denotes |
sequestosome 1 |
| T15057 |
26862-26866 |
Protein |
denotes |
CYLD |
| T15067 |
26876-26892 |
Negative_regulation |
denotes |
deubiquitination |
| T15058 |
26896-26901 |
Protein |
denotes |
TRAF6 |
| T15071 |
26964-26974 |
Gene_expression |
denotes |
expressing |
| T15059 |
26993-26996 |
Protein |
denotes |
p62 |
| T15060 |
27106-27110 |
Protein |
denotes |
CYLD |
| T15061 |
27135-27139 |
Protein |
denotes |
RANK |
| T15062 |
27244-27248 |
Protein |
denotes |
CYLD |
| T16059 |
27336-27379 |
Protein |
denotes |
Single-immunoglobulin IL-1 receptor-related |
| T16060 |
27388-27431 |
Protein |
denotes |
Single-immunoglobulin IL-1 receptor-related |
| T16061 |
27433-27439 |
Protein |
denotes |
SIGIRR |
| T16062 |
27464-27469 |
Protein |
denotes |
TIR-8 |
| T16077 |
27553-27562 |
Negative_regulation |
denotes |
inhibitor |
| T16063 |
27566-27571 |
Protein |
denotes |
IL-1R |
| T16076 |
27616-27627 |
Binding |
denotes |
interaction |
| T16064 |
27650-27655 |
Protein |
denotes |
MyD88 |
| T16065 |
27657-27662 |
Protein |
denotes |
IRAK1 |
| T16066 |
27666-27671 |
Protein |
denotes |
TRAF6 |
| T16068 |
27717-27722 |
Protein |
denotes |
IL-1R |
| T16067 |
27813-27819 |
Protein |
denotes |
SIGIRR |
| T16069 |
27843-27849 |
Protein |
denotes |
SIGIRR |
| T16078 |
27898-27907 |
Gene_expression |
denotes |
expressed |
| T16070 |
28019-28025 |
Protein |
denotes |
SIGIRR |
| T16079 |
28026-28040 |
Positive_regulation |
denotes |
overexpression |
| T16071 |
28168-28174 |
Protein |
denotes |
SIGIRR |
| T16072 |
28212-28218 |
Protein |
denotes |
SIGIRR |
| T16080 |
28219-28228 |
Negative_regulation |
denotes |
deficient |
| T16081 |
28391-28401 |
Gene_expression |
denotes |
expression |
| T16073 |
28405-28411 |
Protein |
denotes |
SIGIRR |
| T16074 |
28510-28516 |
Protein |
denotes |
SIGIRR |
| T16083 |
28574-28584 |
Gene_expression |
denotes |
expression |
| T16075 |
28594-28600 |
Protein |
denotes |
SIGIRR |
| T16082 |
28640-28646 |
Regulation |
denotes |
target |
| T17011 |
28655-28687 |
Protein |
denotes |
TNF receptor-associated factor 1 |
| T17012 |
28688-28693 |
Protein |
denotes |
TRAF1 |
| T17013 |
28798-28807 |
Protein |
denotes |
ubiquitin |
| T17014 |
28862-28867 |
Protein |
denotes |
TRAF1 |
| T17034 |
29015-29025 |
Gene_expression |
denotes |
Expression |
| T17015 |
29029-29034 |
Protein |
denotes |
TRAF1 |
| T17032 |
29038-29047 |
Positive_regulation |
denotes |
inducible |
| T17016 |
29051-29054 |
Protein |
denotes |
TNF |
| T17033 |
29059-29073 |
Positive_regulation |
denotes |
overexpression |
| T17017 |
29077-29082 |
Protein |
denotes |
TRAF1 |
| T17018 |
29092-29095 |
Protein |
denotes |
TNF |
| T17020 |
29122-29127 |
Protein |
denotes |
TRAF1 |
| T17035 |
29128-29137 |
Negative_regulation |
denotes |
deficient |
| T17019 |
29170-29173 |
Protein |
denotes |
TNF |
| T17021 |
29251-29256 |
Protein |
denotes |
TRAF1 |
| T17022 |
29299-29303 |
Protein |
denotes |
CD40 |
| T17023 |
29330-29335 |
Protein |
denotes |
TRAF1 |
| T17036 |
29336-29345 |
Negative_regulation |
denotes |
deficient |
| T17024 |
29426-29431 |
Protein |
denotes |
TRAF2 |
| T17025 |
29528-29533 |
Protein |
denotes |
TRAF1 |
| T17026 |
29595-29600 |
Protein |
denotes |
TRAF1 |
| T17037 |
29639-29646 |
Binding |
denotes |
binding |
| T17027 |
29708-29713 |
Protein |
denotes |
TRAF1 |
| T17039 |
29720-29727 |
Binding |
denotes |
recruit |
| T17028 |
29728-29731 |
Protein |
denotes |
A20 |
| T17038 |
29761-29769 |
Binding |
denotes |
interact |
| T17029 |
29955-29960 |
Protein |
denotes |
TRAF1 |
| T17030 |
30057-30062 |
Protein |
denotes |
TRAF1 |
| T17040 |
30171-30182 |
Binding |
denotes |
association |
| T17031 |
30190-30195 |
Protein |
denotes |
TRAF1 |
| T18509 |
30575-30583 |
Protein |
denotes |
miR-146a |
| T18510 |
30584-30585 |
Protein |
denotes |
b |
| T18511 |
30590-30597 |
Protein |
denotes |
miR-155 |
| T18539 |
30689-30696 |
Positive_regulation |
denotes |
induced |
| T18512 |
30729-30734 |
Protein |
denotes |
IL-1β |
| T18513 |
30736-30739 |
Protein |
denotes |
TNF |
| T18514 |
30771-30779 |
Protein |
denotes |
miR-146a |
| T18515 |
30843-30848 |
Protein |
denotes |
IRAK1 |
| T18516 |
30853-30858 |
Protein |
denotes |
TRAF6 |
| T18517 |
30894-30902 |
Protein |
denotes |
miR-146a |
| T18518 |
30931-30938 |
Protein |
denotes |
miR-155 |
| T18519 |
31006-31010 |
Protein |
denotes |
IKKε |
| T18520 |
31015-31019 |
Protein |
denotes |
RIP1 |
| T18521 |
31055-31062 |
Protein |
denotes |
miR-155 |
| T18540 |
31067-31076 |
Gene_expression |
denotes |
expressed |
| T18522 |
31220-31228 |
Protein |
denotes |
miR-146a |
| T18541 |
31237-31250 |
Gene_expression |
denotes |
overexpressed |
| T18523 |
31254-31257 |
Protein |
denotes |
CD4 |
| T18524 |
31263-31268 |
Protein |
denotes |
IL-17 |
| T18542 |
31269-31278 |
Gene_expression |
denotes |
producing |
| T18525 |
31364-31372 |
Protein |
denotes |
miR-146a |
| T18543 |
31373-31379 |
Binding |
denotes |
target |
| T18526 |
31450-31457 |
Protein |
denotes |
miR-155 |
| T18544 |
31458-31472 |
Positive_regulation |
denotes |
overexpression |
| T18527 |
31651-31658 |
Protein |
denotes |
miR-155 |
| T18546 |
31672-31679 |
Positive_regulation |
denotes |
promote |
| T18528 |
31680-31683 |
Protein |
denotes |
TNF |
| T18545 |
31684-31694 |
Gene_expression |
denotes |
production |
| T18529 |
31754-31761 |
Protein |
denotes |
miR-155 |
| T18530 |
32152-32159 |
Protein |
denotes |
miR-155 |
| T18531 |
32324-32332 |
Protein |
denotes |
miR-124a |
| T18532 |
32368-32402 |
Protein |
denotes |
monocyte chemoattractant protein 1 |
| T18547 |
32421-32430 |
Negative_regulation |
denotes |
decreased |
| T18549 |
32481-32489 |
Positive_regulation |
denotes |
elevated |
| T18533 |
32500-32507 |
Protein |
denotes |
miR-203 |
| T18548 |
32521-32530 |
Positive_regulation |
denotes |
increased |
| T18550 |
32531-32540 |
Localization |
denotes |
secretion |
| T18534 |
32544-32570 |
Protein |
denotes |
matrix metalloproteinase-1 |
| T18535 |
32575-32579 |
Protein |
denotes |
IL-6 |
| T18536 |
32638-32644 |
Protein |
denotes |
miR-16 |
| T18537 |
32646-32653 |
Protein |
denotes |
miR-132 |
| T18538 |
32659-32666 |
Protein |
denotes |
miR-223 |
| R10041 |
T15045 |
T15063 |
themeOf |
A20,expressed |
| R10042 |
T15049 |
T15064 |
themeOf |
CYLD,deficiency |
| R10043 |
T15050 |
T15065 |
themeOf |
RANKL,induced |
| R10044 |
T15051 |
T15066 |
themeOf |
CYLD,expression |
| R10045 |
T15054 |
T15070 |
themeOf |
ubiquitin,binding |
| R10046 |
T15055 |
T15068 |
themeOf |
p62,recruited |
| R10047 |
T15055 |
T15070 |
themeOf |
p62,binding |
| R10048 |
T15058 |
T15067 |
themeOf |
TRAF6,deubiquitination |
| R10049 |
T15059 |
T15071 |
themeOf |
p62,expressing |
| R10050 |
T15066 |
T15069 |
themeOf |
expression,upregulated |
| R1058 |
T1281 |
T1298 |
themeOf |
cyclo-oxygenase-2,expression |
| R1059 |
T1283 |
T1299 |
causeOf |
NF-κB2,regulate |
| R1064 |
T1298 |
T1299 |
themeOf |
expression,regulate |
| R10665 |
T16060 |
T16076 |
themeOf |
Single-immunoglobulin IL-1 receptor-related,interaction |
| R10666 |
T16061 |
T16076 |
themeOf |
SIGIRR,interaction |
| R10667 |
T16062 |
T16076 |
themeOf |
TIR-8,interaction |
| R10668 |
T16063 |
T16076 |
themeOf |
IL-1R,interaction |
| R10669 |
T16065 |
T16077 |
themeOf |
IRAK1,inhibitor |
| R10670 |
T16065 |
T16076 |
themeOf |
IRAK1,interaction |
| R10671 |
T16069 |
T16078 |
themeOf |
SIGIRR,expressed |
| R10672 |
T16070 |
T16079 |
themeOf |
SIGIRR,overexpression |
| R10673 |
T16072 |
T16080 |
themeOf |
SIGIRR,deficient |
| R10674 |
T16073 |
T16081 |
themeOf |
SIGIRR,expression |
| R10675 |
T16075 |
T16082 |
themeOf |
SIGIRR,target |
| R10676 |
T16075 |
T16083 |
themeOf |
SIGIRR,expression |
| R11281 |
T17015 |
T17034 |
themeOf |
TRAF1,Expression |
| R11282 |
T17016 |
T17032 |
causeOf |
TNF,inducible |
| R11283 |
T17017 |
T17033 |
themeOf |
TRAF1,overexpression |
| R11284 |
T17020 |
T17035 |
themeOf |
TRAF1,deficient |
| R11285 |
T17023 |
T17036 |
themeOf |
TRAF1,deficient |
| R11286 |
T17026 |
T17037 |
themeOf |
TRAF1,binding |
| R11287 |
T17027 |
T17039 |
themeOf |
TRAF1,recruit |
| R11288 |
T17028 |
T17038 |
themeOf |
A20,interact |
| R11289 |
T17028 |
T17039 |
themeOf |
A20,recruit |
| R11290 |
T17031 |
T17040 |
themeOf |
TRAF1,association |
| R11291 |
T17034 |
T17032 |
themeOf |
Expression,inducible |
| R12357 |
T18512 |
T18539 |
themeOf |
IL-1β,induced |
| R12358 |
T18513 |
T18539 |
causeOf |
TNF,induced |
| R12359 |
T18521 |
T18540 |
themeOf |
miR-155,expressed |
| R12360 |
T18522 |
T18541 |
themeOf |
miR-146a,overexpressed |
| R12361 |
T18524 |
T18542 |
themeOf |
IL-17,producing |
| R12362 |
T18525 |
T18543 |
themeOf |
miR-146a,target |
| R12363 |
T18526 |
T18544 |
themeOf |
miR-155,overexpression |
| R12364 |
T18528 |
T18545 |
themeOf |
TNF,production |
| R12365 |
T18531 |
T18547 |
themeOf |
miR-124a,decreased |
| R12366 |
T18533 |
T18549 |
themeOf |
miR-203,elevated |
| R12367 |
T18534 |
T18548 |
themeOf |
matrix metalloproteinase-1,increased |
| R12368 |
T18534 |
T18550 |
themeOf |
matrix metalloproteinase-1,secretion |
| R12369 |
T18535 |
T18548 |
themeOf |
IL-6,increased |
| R12370 |
T18535 |
T18550 |
themeOf |
IL-6,secretion |
| R12371 |
T18545 |
T18546 |
themeOf |
production,promote |
| R12372 |
T18550 |
T18548 |
themeOf |
secretion,increased |
| R12373 |
T18550 |
T18548 |
themeOf |
secretion,increased |
| R13674 |
T20590 |
T20647 |
themeOf |
TNFR1,engagement |
| R13675 |
T20591 |
T20646 |
themeOf |
TRIF,recruitment |
| R13676 |
T20592 |
T20646 |
themeOf |
RIP1,recruitment |
| R13677 |
T20593 |
T20646 |
themeOf |
IRAK1,recruitment |
| R13678 |
T20594 |
T20646 |
themeOf |
IRAK4,recruitment |
| R13679 |
T20595 |
T20646 |
themeOf |
TRAF2,recruitment |
| R13680 |
T20596 |
T20646 |
themeOf |
TRAF6,recruitment |
| R13681 |
T20597 |
T20646 |
themeOf |
cIAP1,recruitment |
| R13682 |
T20598 |
T20646 |
themeOf |
cIAP2,recruitment |
| R13683 |
T20601 |
T20647 |
themeOf |
TLR4,engagement |
| R13684 |
T20602 |
T20646 |
themeOf |
TNF receptor 1-associated death domain protein,recruitment |
| R13685 |
T20603 |
T20646 |
themeOf |
TRADD,recruitment |
| R13686 |
T20604 |
T20646 |
themeOf |
MyD88,recruitment |
| R13687 |
T20605 |
T20646 |
themeOf |
MAL,recruitment |
| R13688 |
T20606 |
T20646 |
themeOf |
TIR domain-containing adaptor-inducing IFNβ,recruitment |
| R13689 |
T20607 |
T20649 |
themeOf |
RIP1,polyubiquitination |
| R13690 |
T20608 |
T20649 |
themeOf |
IRAK1,polyubiquitination |
| R13691 |
T20610 |
T20650 |
themeOf |
IKK2,recruitment |
| R13692 |
T20611 |
T20650 |
themeOf |
TAK1,recruitment |
| R13693 |
T20612 |
T20651 |
themeOf |
TAK1,phosphorylates |
| R13694 |
T20612 |
T20652 |
causeOf |
TAK1,activates |
| R13695 |
T20613 |
T20651 |
themeOf |
IKK2,phosphorylates |
| R13696 |
T20613 |
T20652 |
themeOf |
IKK2,activates |
| R13697 |
T20614 |
T20653 |
themeOf |
IκBα,phosphorylates |
| R13698 |
T20620 |
T20654 |
themeOf |
RIP1,targeting |
| R13699 |
T20624 |
T20656 |
themeOf |
IRAK1,expression |
| R13700 |
T20625 |
T20656 |
themeOf |
TRAF6,expression |
| R13701 |
T20626 |
T20659 |
themeOf |
SIGIRR,inhibited |
| R13702 |
T20627 |
T20657 |
themeOf |
TLR4,compete |
| R13703 |
T20627 |
T20658 |
themeOf |
TLR4,binding |
| R13704 |
T20627 |
T20658 |
themeOf |
TLR4,binding |
| R13705 |
T20628 |
T20658 |
themeOf |
IRAK1,binding |
| R13706 |
T20629 |
T20658 |
themeOf |
TRAF6,binding |
| R13707 |
T20650 |
T20648 |
themeOf |
recruitment,resulting |
| R13708 |
T20650 |
T20648 |
themeOf |
recruitment,resulting |
| R13709 |
T20656 |
T20655 |
themeOf |
expression,inhibiting |
| R13710 |
T20656 |
T20655 |
themeOf |
expression,inhibiting |
| R13711 |
T20658 |
T20657 |
themeOf |
binding,compete |
| R13712 |
T20658 |
T20657 |
themeOf |
binding,compete |
| R14446 |
T22109 |
T22141 |
themeOf |
NF-κB inducing kinase,dependent |
| R14447 |
T22109 |
T22142 |
themeOf |
NF-κB inducing kinase,expression |
| R14448 |
T22110 |
T22142 |
themeOf |
NIK,expression |
| R14449 |
T22111 |
T22143 |
themeOf |
NIK,polyubiquitination |
| R14450 |
T22111 |
T22144 |
themeOf |
NIK,degradation |
| R14451 |
T22118 |
T22145 |
themeOf |
TRAF3,recruited |
| R14452 |
T22120 |
T22147 |
themeOf |
cIAP1,polyubiquitination |
| R14453 |
T22120 |
T22146 |
themeOf |
cIAP1,activation |
| R14454 |
T22121 |
T22147 |
themeOf |
2,polyubiquitination |
| R14455 |
T22124 |
T22148 |
themeOf |
TRAF3,polyubiquitination |
| R14456 |
T22125 |
T22148 |
themeOf |
NIK,polyubiquitination |
| R14457 |
T22126 |
T22149 |
themeOf |
TRAF3,degraded |
| R14458 |
T22128 |
T22150 |
themeOf |
NIK,increased |
| R14459 |
T22129 |
T22153 |
themeOf |
NIK,phosphorylates |
| R14460 |
T22129 |
T22154 |
causeOf |
NIK,activates |
| R14461 |
T22130 |
T22153 |
themeOf |
IKK1,phosphorylates |
| R14462 |
T22130 |
T22154 |
themeOf |
IKK1,activates |
| R14463 |
T22130 |
T22151 |
causeOf |
IKK1,mediates |
| R14464 |
T22131 |
T22152 |
themeOf |
p100,phosphorylation |
| R14465 |
T22132 |
T22155 |
themeOf |
p100,degradation |
| R14466 |
T22133 |
T22155 |
themeOf |
p52,degradation |
| R14467 |
T22142 |
T22141 |
themeOf |
expression,dependent |
| R14468 |
T22142 |
T22141 |
themeOf |
expression,dependent |
| R14469 |
T22152 |
T22151 |
themeOf |
phosphorylation,mediates |
| R2612 |
T3294 |
T3319 |
themeOf |
CD40,expressed |
| R2613 |
T3295 |
T3318 |
themeOf |
TNF receptor family member,upregulated |
| R2614 |
T3295 |
T3319 |
themeOf |
TNF receptor family member,expressed |
| R2616 |
T3297 |
T3321 |
themeOf |
CD40 ligand,expressed |
| R2617 |
T3297 |
T3320 |
themeOf |
CD40 ligand,Binding |
| R2618 |
T3298 |
T3321 |
themeOf |
CD154,expressed |
| R2619 |
T3298 |
T3320 |
themeOf |
CD154,Binding |
| R2621 |
T3301 |
T3322 |
themeOf |
B-cell activating factor,expression |
| R2623 |
T3302 |
T3322 |
themeOf |
BAFF,expression |
| R2627 |
T3305 |
T3325 |
themeOf |
High mobility group box chromosomal protein 1,released |
| R2628 |
T3307 |
T3324 |
themeOf |
chromatin component,secreted |
| R2629 |
T3307 |
T3325 |
themeOf |
chromatin component,released |
| R2630 |
T3309 |
T3326 |
themeOf |
HMGB1,increased |
| R2633 |
T3314 |
T3327 |
themeOf |
TLR4,induced |
| R2637 |
T3322 |
T3323 |
themeOf |
expression,Enhanced |
| R2638 |
T3322 |
T3323 |
themeOf |
expression,Enhanced |
| R4903 |
T6964 |
T7053 |
causeOf |
IKK2,required |
| R4905 |
T6965 |
T7053 |
themeOf |
NEMO,required |
| R4906 |
T6965 |
T7053 |
themeOf |
NEMO,required |
| R4907 |
T6966 |
T7053 |
causeOf |
IKK1,required |
| R4909 |
T6969 |
T7054 |
themeOf |
TNF receptor-1-associated death domain,recruitment |
| R4910 |
T6970 |
T7054 |
themeOf |
TRADD,recruitment |
| R4911 |
T6971 |
T7054 |
themeOf |
receptor interacting protein 1,recruitment |
| R4913 |
T6972 |
T7054 |
themeOf |
RIP1,recruitment |
| R4915 |
T6975 |
T7055 |
themeOf |
cellular inhibitor of apoptosis (cIAP) 1,bind |
| R4916 |
T6976 |
T7055 |
themeOf |
cIAP2,bind |
| R4919 |
T6978 |
T7056 |
themeOf |
RIP1,bound |
| R4922 |
T6983 |
T7057 |
themeOf |
RIP1,ubiquitination |
| R4924 |
T6986 |
T7058 |
themeOf |
NEMO,recruit |
| R4925 |
T6987 |
T7058 |
themeOf |
TAB1,recruit |
| R4927 |
T6988 |
T7058 |
themeOf |
2,recruit |
| R4928 |
T6989 |
T7059 |
themeOf |
NEMO,modifies |
| R4930 |
T6992 |
T7063 |
themeOf |
TLR4,stimulation |
| R4932 |
T6993 |
T7060 |
themeOf |
Toll/IL-1 receptor adaptor protein,recruitment |
| R4933 |
T6995 |
T7060 |
themeOf |
TRIF-related adaptor molecule,recruitment |
| R4935 |
T6996 |
T7060 |
themeOf |
TRAM,recruitment |
| R4936 |
T6997 |
T7062 |
themeOf |
myeloid differentiation primary response gene 88,recruit |
| R4937 |
T6998 |
T7062 |
themeOf |
MyD88,recruit |
| R4939 |
T6999 |
T7062 |
themeOf |
TIR domain-containing adaptor-inducing IFNβ,recruit |
| R4940 |
T7000 |
T7062 |
themeOf |
TRIF,recruit |
| R4942 |
T7004 |
T7064 |
themeOf |
TRIF,interaction |
| R4944 |
T7005 |
T7064 |
themeOf |
TRAF6,interaction |
| R4945 |
T7005 |
T7065 |
themeOf |
TRAF6,recruits |
| R4946 |
T7006 |
T7065 |
themeOf |
RIP1,recruits |
| R4947 |
T7007 |
T7066 |
themeOf |
TAK1,activate |
| R4952 |
T7016 |
T7067 |
causeOf |
IKK1,activated |
| R4954 |
T7017 |
T7067 |
themeOf |
NF-κB inducing kinase,activated |
| R4956 |
T7019 |
T7068 |
themeOf |
NIK,regulated |
| R4959 |
T7025 |
T7069 |
themeOf |
2,degradation |
| R4960 |
T7026 |
T7074 |
themeOf |
TRAF3,remove |
| R4961 |
T7026 |
T7073 |
themeOf |
TRAF3,recruiting |
| R4962 |
T7027 |
T7072 |
themeOf |
TRAF2,attract |
| R4963 |
T7028 |
T7072 |
themeOf |
cIAP1,attract |
| R4964 |
T7029 |
T7072 |
themeOf |
2,attract |
| R4965 |
T7030 |
T7070 |
themeOf |
TRAF3,degradation |
| R4966 |
T7031 |
T7077 |
themeOf |
NIK,degradation |
| R4967 |
T7031 |
T7075 |
themeOf |
NIK,releasing |
| R4968 |
T7032 |
T7078 |
themeOf |
NIK,accumulation |
| R4969 |
T7033 |
T7079 |
themeOf |
IKK1,phosphorylation |
| R4970 |
T7037 |
T7080 |
themeOf |
CD40,interact |
| R4971 |
T7038 |
T7080 |
themeOf |
RANK,interact |
| R4972 |
T7047 |
T7081 |
causeOf |
TRAF6,required |
| R4977 |
T7049 |
T7082 |
themeOf |
IL-6,production |
| R4986 |
T7050 |
T7083 |
themeOf |
TRAF2,required |
| R5008 |
T7060 |
T7061 |
themeOf |
recruitment,induces |
| R5031 |
T7060 |
T7061 |
themeOf |
recruitment,induces |
| R5038 |
T7060 |
T7061 |
themeOf |
recruitment,induces |
| R5039 |
T7063 |
T7061 |
causeOf |
stimulation,induces |
| R5050 |
T7063 |
T7061 |
causeOf |
stimulation,induces |
| R5051 |
T7063 |
T7061 |
causeOf |
stimulation,induces |
| R5052 |
T7070 |
T7071 |
themeOf |
degradation,essential |
| R5067 |
T7077 |
T7075 |
themeOf |
degradation,releasing |
| R5072 |
T7078 |
T7076 |
themeOf |
accumulation,resulting |
| R5075 |
T7079 |
T7076 |
themeOf |
phosphorylation,resulting |
| R5076 |
T7082 |
T7081 |
themeOf |
production,required |
| R6247 |
T9132 |
T9145 |
themeOf |
IKK1,deficient |
| R6248 |
T9133 |
T9141 |
themeOf |
IKK1,expressing |
| R6249 |
T9134 |
T9142 |
themeOf |
IKK2,activation |
| R6250 |
T9135 |
T9143 |
themeOf |
IκBα,degradation |
| R6251 |
T9136 |
T9147 |
themeOf |
STAT1,phosphorylating |
| R6252 |
T9139 |
T9148 |
themeOf |
NIK,phosphorylates |
| R6253 |
T9142 |
T9146 |
themeOf |
activation,enhanced |
| R6254 |
T9143 |
T9144 |
themeOf |
degradation,result |
| R8025 |
T11755 |
T11806 |
themeOf |
Ubc13,disruption |
| R8028 |
T11756 |
T11806 |
themeOf |
Ubc5hc,disruption |
| R8030 |
T11759 |
T11806 |
themeOf |
cIAP1,disruption |
| R8032 |
T11762 |
T11807 |
themeOf |
A20,association |
| R8036 |
T11763 |
T11808 |
themeOf |
A20-binding inhibitor of NF-κB (ABIN) 1,requires |
| R8038 |
T11765 |
T11810 |
themeOf |
A20,inhibitor |
| R8040 |
T11767 |
T11811 |
themeOf |
A20,deficient |
| R8042 |
T11768 |
T11812 |
themeOf |
A20,deficient |
| R8045 |
T11770 |
T11814 |
themeOf |
A20,lacking |
| R8047 |
T11771 |
T11813 |
themeOf |
TNF,induced |
| R8049 |
T11773 |
T11815 |
themeOf |
A20,lacking |
| R8050 |
T11774 |
T11816 |
themeOf |
A20,expression |
| R8051 |
T11775 |
T11817 |
themeOf |
A20,expression |
| R8053 |
T11777 |
T11819 |
themeOf |
A20,expressing |
| R8054 |
T11778 |
T11821 |
themeOf |
A20,expression |
| R8056 |
T11779 |
T11822 |
themeOf |
TNF,inhibition |
| R8057 |
T11779 |
T11823 |
themeOf |
TNF,decreased |
| R8058 |
T11780 |
T11822 |
themeOf |
IL-1β,inhibition |
| R8059 |
T11780 |
T11823 |
themeOf |
IL-1β,decreased |
| R8060 |
T11781 |
T11822 |
themeOf |
IL-6,inhibition |
| R8061 |
T11781 |
T11823 |
themeOf |
IL-6,decreased |
| R8062 |
T11782 |
T11823 |
themeOf |
RANKL,decreased |
| R8064 |
T11783 |
T11823 |
themeOf |
monocyte chemo-attractant protein 1,decreased |
| R8065 |
T11784 |
T11824 |
themeOf |
A20,induces |
| R8066 |
T11784 |
T11820 |
themeOf |
A20,expression |
| R8068 |
T11787 |
T11825 |
themeOf |
TNF,decreased |
| R8069 |
T11788 |
T11825 |
themeOf |
IL-1β,decreased |
| R8071 |
T11790 |
T11826 |
themeOf |
A20,overexpression |
| R8073 |
T11792 |
T11827 |
themeOf |
A20,lack |
| R8074 |
T11794 |
T11828 |
themeOf |
A20,association |
| R8076 |
T11795 |
T11829 |
themeOf |
A20,influence |
| R8078 |
T11797 |
T11831 |
themeOf |
A20,required |
| R8079 |
T11798 |
T11830 |
themeOf |
TNF,induced |
| R8082 |
T11804 |
T11832 |
themeOf |
A20,transcription |
| R8084 |
T11807 |
T11809 |
themeOf |
association,targets |
| R8085 |
T11807 |
T11808 |
causeOf |
association,requires |
| R8093 |
T11817 |
T11818 |
themeOf |
expression,regulated |
| R8095 |
T11822 |
T11823 |
themeOf |
inhibition,decreased |
| R8096 |
T11822 |
T11823 |
themeOf |
inhibition,decreased |
| R8097 |
T11822 |
T11823 |
themeOf |
inhibition,decreased |
| R8101 |
T11832 |
T11833 |
themeOf |
transcription,repressed |
| R9156 |
T13628 |
T13659 |
themeOf |
A20,binding |
| R9157 |
T13630 |
T13660 |
themeOf |
ABIN-2,expressed |
| R9158 |
T13635 |
T13661 |
themeOf |
A20,interacting |
| R9159 |
T13635 |
T13660 |
themeOf |
A20,expressed |
| R9160 |
T13637 |
T13662 |
themeOf |
A20,target |
| R9161 |
T13639 |
T13663 |
themeOf |
ABIN-1,expression |
| R9162 |
T13640 |
T13663 |
themeOf |
ABIN-3,expression |
| R9163 |
T13642 |
T13664 |
themeOf |
ABIN-1,deficient |
| R9164 |
T13643 |
T13665 |
themeOf |
ABIN-2,deficient |
| R9165 |
T13644 |
T13667 |
themeOf |
ABIN-3,expressed |
| R9166 |
T13645 |
T13668 |
themeOf |
truncated and inactive form,express |
| R9167 |
T13645 |
T13666 |
themeOf |
truncated and inactive form,lacking |
| R9168 |
T13646 |
T13670 |
themeOf |
A20,inhibits |
| R9169 |
T13647 |
T13670 |
causeOf |
ABIN-1,inhibits |
| R9170 |
T13648 |
T13671 |
themeOf |
TNF,induced |
| R9171 |
T13649 |
T13669 |
themeOf |
ABIN-1,deficient |
| R9172 |
T13652 |
T13672 |
themeOf |
TNF,induced |
| R9173 |
T13656 |
T13673 |
themeOf |
ABIN-3,expression |
| R9174 |
T13657 |
T13673 |
themeOf |
A20,expression |
| R9175 |
T13673 |
T13674 |
themeOf |
expression,depend |
| R9176 |
T13673 |
T13674 |
themeOf |
expression,depend |
