| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T363 |
4-13 |
Regulation |
denotes |
Regulates |
| T353 |
14-18 |
Protein |
denotes |
TNFα |
| T364 |
19-28 |
Gene_expression |
denotes |
Synthesis |
| T354 |
43-47 |
Protein |
denotes |
RIP1 |
| T365 |
55-65 |
Positive_regulation |
denotes |
Activation |
| T355 |
443-473 |
Protein |
denotes |
receptor interacting protein-1 |
| T356 |
475-479 |
Protein |
denotes |
RIP1 |
| T366 |
580-584 |
Regulation |
denotes |
role |
| T357 |
588-592 |
Protein |
denotes |
TNFα |
| T367 |
593-603 |
Gene_expression |
denotes |
production |
| T358 |
647-651 |
Protein |
denotes |
RIP1 |
| T359 |
807-811 |
Protein |
denotes |
RIP1 |
| T368 |
967-972 |
Positive_regulation |
denotes |
links |
| T360 |
973-977 |
Protein |
denotes |
RIP1 |
| T361 |
1024-1028 |
Protein |
denotes |
TNFα |
| T362 |
1149-1153 |
Protein |
denotes |
TNFα |
| T369 |
1154-1164 |
Gene_expression |
denotes |
production |
| T1769 |
2081-2088 |
Binding |
denotes |
complex |
| T1750 |
2132-2136 |
Protein |
denotes |
RIP1 |
| T1751 |
2141-2145 |
Protein |
denotes |
RIP3 |
| T1752 |
2757-2761 |
Protein |
denotes |
RIP1 |
| T1753 |
2766-2770 |
Protein |
denotes |
RIP3 |
| T1754 |
2964-2968 |
Protein |
denotes |
RIP1 |
| T1755 |
3015-3020 |
Protein |
denotes |
c-Jun |
| T1756 |
3180-3184 |
Protein |
denotes |
TNFα |
| T1770 |
3185-3194 |
Gene_expression |
denotes |
synthesis |
| T1757 |
3308-3312 |
Protein |
denotes |
RIP1 |
| T6379 |
3308-3312 |
Protein |
denotes |
RIP1 |
| T1758 |
3352-3356 |
Protein |
denotes |
TNFα |
| T1771 |
3357-3367 |
Gene_expression |
denotes |
production |
| T1759 |
3627-3634 |
Protein |
denotes |
insulin |
| T1760 |
4106-4113 |
Protein |
denotes |
insulin |
| T1761 |
4284-4288 |
Protein |
denotes |
RIP1 |
| T1762 |
4472-4476 |
Protein |
denotes |
RIP1 |
| T1772 |
4532-4541 |
Positive_regulation |
denotes |
activated |
| T14928 |
4550-4554 |
Protein |
denotes |
RIP1 |
| T1763 |
4550-4554 |
Protein |
denotes |
RIP1 |
| T14962 |
4555-4571 |
Positive_regulation |
denotes |
kinase-dependent |
| T1774 |
4555-4571 |
Positive_regulation |
denotes |
kinase-dependent |
| T14963 |
4579-4594 |
Phosphorylation |
denotes |
phosphorylation |
| T1773 |
4579-4594 |
Phosphorylation |
denotes |
phosphorylation |
| T1764 |
4709-4711 |
Protein |
denotes |
S6 |
| T1776 |
4731-4741 |
Positive_regulation |
denotes |
activation |
| T1765 |
4761-4765 |
Protein |
denotes |
TNFα |
| T1775 |
4766-4776 |
Gene_expression |
denotes |
production |
| T1766 |
4842-4846 |
Protein |
denotes |
RIP1 |
| T1767 |
4955-4959 |
Protein |
denotes |
FADD |
| T1768 |
5076-5080 |
Protein |
denotes |
TNFα |
| T1777 |
5081-5091 |
Gene_expression |
denotes |
production |
| T3917 |
5289-5319 |
Protein |
denotes |
Basic Fibroblast Growth Factor |
| T3918 |
5472-5476 |
Protein |
denotes |
TNFα |
| T3946 |
5502-5512 |
Negative_regulation |
denotes |
inhibition |
| T3919 |
5516-5525 |
Protein |
denotes |
caspase-8 |
| T3947 |
5949-5953 |
Negative_regulation |
denotes |
loss |
| T3920 |
5987-5996 |
Protein |
denotes |
caspase-8 |
| T3921 |
6001-6005 |
Protein |
denotes |
FADD |
| T3922 |
6411-6420 |
Protein |
denotes |
caspase-8 |
| T3948 |
6449-6460 |
Negative_regulation |
denotes |
inactivates |
| T3923 |
6461-6465 |
Protein |
denotes |
RIP1 |
| T3924 |
6481-6500 |
Protein |
denotes |
RIP1 deubiquitinase |
| T3925 |
6501-6505 |
Protein |
denotes |
CYLD |
| T3926 |
6726-6730 |
Protein |
denotes |
bFGF |
| T3927 |
6920-6924 |
Protein |
denotes |
bFGF |
| T3928 |
6929-6934 |
Protein |
denotes |
IGF-1 |
| T3929 |
6944-6947 |
Protein |
denotes |
EGF |
| T3930 |
7081-7085 |
Protein |
denotes |
bFGF |
| T3931 |
7142-7146 |
Protein |
denotes |
TNFα |
| T3932 |
7278-7282 |
Protein |
denotes |
TNFα |
| T28686 |
7377-7381 |
Protein |
denotes |
bFGF |
| T28687 |
7386-7391 |
Protein |
denotes |
IGF-1 |
| T28688 |
7471-7475 |
Protein |
denotes |
TNFα |
| T28689 |
8080-8084 |
Protein |
denotes |
TNFα |
| T3949 |
8294-8303 |
Negative_regulation |
denotes |
inhibitor |
| T3933 |
8307-8311 |
Protein |
denotes |
RIP1 |
| T3934 |
8606-8610 |
Protein |
denotes |
TNFα |
| T3935 |
8707-8711 |
Protein |
denotes |
RIP1 |
| T3950 |
8845-8849 |
Negative_regulation |
denotes |
loss |
| T3936 |
8853-8857 |
Protein |
denotes |
RIP1 |
| T3937 |
8992-8996 |
Protein |
denotes |
TNFα |
| T3938 |
9046-9050 |
Protein |
denotes |
bFGF |
| T3939 |
9091-9095 |
Protein |
denotes |
RIP1 |
| T3940 |
9217-9221 |
Protein |
denotes |
bFGF |
| T3941 |
9319-9348 |
Protein |
denotes |
bFGF receptor tyrosine kinase |
| T3951 |
9349-9359 |
Negative_regulation |
denotes |
inhibitors |
| T3942 |
9419-9423 |
Protein |
denotes |
bFGF |
| T3943 |
9544-9557 |
Protein |
denotes |
bFGF receptor |
| T3952 |
9558-9567 |
Negative_regulation |
denotes |
inhibitor |
| T3944 |
9590-9594 |
Protein |
denotes |
TNFα |
| T3945 |
9792-9796 |
Protein |
denotes |
bFGF |
| T6380 |
10595-10599 |
Protein |
denotes |
bFGF |
| T6381 |
10603-10608 |
Protein |
denotes |
IGF-1 |
| T6382 |
10750-10754 |
Protein |
denotes |
TNFα |
| T6383 |
10870-10874 |
Protein |
denotes |
TNFα |
| T6384 |
11088-11092 |
Protein |
denotes |
TNFα |
| T29100 |
11217-11221 |
Protein |
denotes |
TNFα |
| T29101 |
11268-11272 |
Protein |
denotes |
TNFα |
| T29106 |
11499-11510 |
Gene_expression |
denotes |
transfected |
| T29102 |
11516-11520 |
Protein |
denotes |
Akt1 |
| T29103 |
11522-11526 |
Protein |
denotes |
Akt2 |
| T29104 |
11532-11543 |
Protein |
denotes |
Akt3 siRNAs |
| T29105 |
11585-11589 |
Protein |
denotes |
TNFα |
| T6413 |
12035-12044 |
Negative_regulation |
denotes |
knockdown |
| T6385 |
12061-12065 |
Protein |
denotes |
Akt1 |
| T6386 |
12070-12074 |
Protein |
denotes |
Akt2 |
| T6387 |
12150-12154 |
Protein |
denotes |
TNFα |
| T6414 |
12169-12179 |
Gene_expression |
denotes |
expression |
| T6388 |
12183-12187 |
Protein |
denotes |
Akt3 |
| T6389 |
12241-12251 |
Protein |
denotes |
Akt3 siRNA |
| T6390 |
12555-12559 |
Protein |
denotes |
TNFα |
| T6391 |
12725-12729 |
Protein |
denotes |
TNFα |
| T6416 |
12977-12985 |
Positive_regulation |
denotes |
increase |
| T6415 |
12993-13008 |
Phosphorylation |
denotes |
phosphorylation |
| T6392 |
13021-13024 |
Protein |
denotes |
p46 |
| T6393 |
13029-13032 |
Protein |
denotes |
p54 |
| T6394 |
13073-13078 |
Protein |
denotes |
c-Jun |
| T29642 |
13220-13224 |
Protein |
denotes |
RIP1 |
| T29648 |
13225-13241 |
Regulation |
denotes |
kinase-dependent |
| T29647 |
13242-13257 |
Phosphorylation |
denotes |
phosphorylation |
| T29643 |
13338-13342 |
Protein |
denotes |
TNFα |
| T29644 |
13460-13464 |
Protein |
denotes |
bFGF |
| T29645 |
13624-13628 |
Protein |
denotes |
bFGF |
| T29646 |
13632-13636 |
Protein |
denotes |
bFGF |
| T6395 |
13745-13749 |
Protein |
denotes |
RIP1 |
| T6420 |
13757-13766 |
Negative_regulation |
denotes |
inhibitor |
| T6417 |
13786-13795 |
Negative_regulation |
denotes |
prevented |
| T6419 |
13800-13808 |
Positive_regulation |
denotes |
increase |
| T6396 |
13819-13822 |
Protein |
denotes |
Akt |
| T6418 |
13823-13838 |
Phosphorylation |
denotes |
phosphorylation |
| T6397 |
14014-14018 |
Protein |
denotes |
TNFα |
| T6421 |
14046-14053 |
Regulation |
denotes |
changes |
| T6398 |
14089-14094 |
Protein |
denotes |
c-Jun |
| T6422 |
14175-14183 |
Positive_regulation |
denotes |
increase |
| T6399 |
14187-14192 |
Protein |
denotes |
c-Jun |
| T6400 |
14402-14406 |
Protein |
denotes |
RIP1 |
| T6401 |
14698-14702 |
Protein |
denotes |
RIP1 |
| T6402 |
14869-14873 |
Protein |
denotes |
bFGF |
| T6423 |
14953-14961 |
Positive_regulation |
denotes |
increase |
| T6403 |
15030-15035 |
Protein |
denotes |
c-Jun |
| T6404 |
15158-15162 |
Protein |
denotes |
bFGF |
| T6405 |
15181-15185 |
Protein |
denotes |
bFGF |
| T6427 |
15424-15432 |
Positive_regulation |
denotes |
increase |
| T6406 |
15453-15458 |
Protein |
denotes |
c-Jun |
| T6424 |
15459-15474 |
Phosphorylation |
denotes |
phosphorylation |
| T6407 |
15493-15497 |
Protein |
denotes |
bFGF |
| T6408 |
15502-15506 |
Protein |
denotes |
bFGF |
| T6428 |
15585-15592 |
Negative_regulation |
denotes |
blocked |
| T6409 |
15597-15601 |
Protein |
denotes |
bFGF |
| T6425 |
15607-15615 |
Positive_regulation |
denotes |
increase |
| T6426 |
15728-15737 |
Positive_regulation |
denotes |
dependent |
| T6410 |
15741-15745 |
Protein |
denotes |
RIP1 |
| T6411 |
16165-16169 |
Protein |
denotes |
RIP1 |
| T6412 |
16449-16453 |
Protein |
denotes |
RIP1 |
| T7670 |
16463-16467 |
Protein |
denotes |
TNFα |
| T7671 |
16584-16588 |
Protein |
denotes |
TNFα |
| T7672 |
16687-16691 |
Protein |
denotes |
TNFα |
| T7681 |
16692-16699 |
Positive_regulation |
denotes |
induced |
| T7673 |
16843-16847 |
Protein |
denotes |
TNFα |
| T7674 |
16976-16980 |
Protein |
denotes |
TNFα |
| T7675 |
17069-17073 |
Protein |
denotes |
TNFα |
| T7676 |
17133-17137 |
Protein |
denotes |
TNFα |
| T7683 |
17175-17183 |
Positive_regulation |
denotes |
increase |
| T7682 |
17191-17206 |
Phosphorylation |
denotes |
phosphorylation |
| T7677 |
17218-17223 |
Protein |
denotes |
c-Jun |
| T7680 |
17377-17381 |
Protein |
denotes |
RIP1 |
| T7678 |
17476-17480 |
Protein |
denotes |
Ask1 |
| T7679 |
17517-17521 |
Protein |
denotes |
RIP1 |
| T8426 |
17698-17702 |
Protein |
denotes |
RIP1 |
| T8431 |
17720-17728 |
Positive_regulation |
denotes |
increase |
| T8427 |
18244-18248 |
Protein |
denotes |
TNFα |
| T8428 |
18252-18256 |
Protein |
denotes |
bFGF |
| T8429 |
18462-18466 |
Protein |
denotes |
bFGF |
| T8430 |
18501-18505 |
Protein |
denotes |
bFGF |
| T29942 |
19117-19121 |
Protein |
denotes |
bFGF |
| T29943 |
19237-19241 |
Protein |
denotes |
TNFα |
| T29944 |
19249-19253 |
Protein |
denotes |
bFGF |
| T29945 |
19503-19507 |
Protein |
denotes |
bFGF |
| T29946 |
19738-19742 |
Protein |
denotes |
bFGF |
| T10215 |
20088-20096 |
Positive_regulation |
denotes |
increase |
| T10214 |
20104-20119 |
Phosphorylation |
denotes |
phosphorylation |
| T10172 |
20216-20231 |
Protein |
denotes |
double minute 2 |
| T10173 |
20233-20237 |
Protein |
denotes |
MDM2 |
| T10174 |
20273-20304 |
Protein |
denotes |
p70 ribosomal protein S6 Kinase |
| T10175 |
20306-20312 |
Protein |
denotes |
p70S6K |
| T10176 |
20315-20317 |
Protein |
denotes |
S6 |
| T10177 |
20345-20350 |
Protein |
denotes |
FoxO1 |
| T10178 |
20352-20357 |
Protein |
denotes |
FoxO4 |
| T10179 |
20359-20363 |
Protein |
denotes |
MDM2 |
| T10216 |
20375-20383 |
Positive_regulation |
denotes |
increase |
| T10184 |
20414-20420 |
Protein |
denotes |
FoxO3a |
| T10180 |
20422-20428 |
Protein |
denotes |
GSK-3α |
| T10181 |
20429-20430 |
Protein |
denotes |
β |
| T10182 |
20432-20438 |
Protein |
denotes |
p70S6K |
| T10183 |
20457-20459 |
Protein |
denotes |
S6 |
| T10185 |
20629-20635 |
Protein |
denotes |
pFoxO1 |
| T10217 |
20697-20705 |
Positive_regulation |
denotes |
increase |
| T10186 |
21124-21128 |
Protein |
denotes |
RIP1 |
| T30542 |
21290-21294 |
Protein |
denotes |
TNFα |
| T30543 |
21390-21394 |
Protein |
denotes |
bFGF |
| T30544 |
21398-21402 |
Protein |
denotes |
bFGF |
| T30545 |
21551-21555 |
Protein |
denotes |
TNFα |
| T30546 |
21764-21768 |
Protein |
denotes |
TNFα |
| T10218 |
22209-22218 |
Negative_regulation |
denotes |
inhibitor |
| T10187 |
22241-22247 |
Protein |
denotes |
Raptor |
| T10188 |
22616-22620 |
Protein |
denotes |
TNFα |
| T10219 |
22683-22693 |
Positive_regulation |
denotes |
activation |
| T10189 |
22697-22709 |
Protein |
denotes |
p70S6 kinase |
| T10190 |
22747-22749 |
Protein |
denotes |
S6 |
| T10222 |
22912-22921 |
Negative_regulation |
denotes |
inhibitor |
| T10191 |
22925-22931 |
Protein |
denotes |
p70S6K |
| T10220 |
23005-23010 |
Negative_regulation |
denotes |
block |
| T10192 |
23011-23013 |
Protein |
denotes |
S6 |
| T10221 |
23014-23029 |
Phosphorylation |
denotes |
phosphorylation |
| T10223 |
23059-23068 |
Negative_regulation |
denotes |
knockdown |
| T10193 |
23072-23074 |
Protein |
denotes |
S6 |
| T10194 |
23167-23173 |
Protein |
denotes |
p70S6K |
| T10195 |
23174-23176 |
Protein |
denotes |
S6 |
| T10196 |
23422-23426 |
Protein |
denotes |
RIP1 |
| T10225 |
23455-23462 |
Regulation |
denotes |
control |
| T10224 |
23467-23479 |
Positive_regulation |
denotes |
upregulation |
| T10197 |
23483-23487 |
Protein |
denotes |
TNFα |
| T10226 |
23635-23644 |
Positive_regulation |
denotes |
increased |
| T10227 |
23645-23654 |
Gene_expression |
denotes |
synthesis |
| T10198 |
23658-23662 |
Protein |
denotes |
TNFα |
| T10228 |
23747-23757 |
Positive_regulation |
denotes |
contribute |
| T10199 |
23761-23765 |
Protein |
denotes |
TNFα |
| T10229 |
23766-23775 |
Gene_expression |
denotes |
synthesis |
| T10200 |
23795-23799 |
Protein |
denotes |
RIP1 |
| T10230 |
23810-23818 |
Positive_regulation |
denotes |
increase |
| T10201 |
23822-23826 |
Protein |
denotes |
TNFα |
| T10202 |
23864-23868 |
Protein |
denotes |
TNFα |
| T10231 |
23874-23880 |
Transcription |
denotes |
levels |
| T10232 |
23881-23890 |
Positive_regulation |
denotes |
increased |
| T10203 |
23929-23933 |
Protein |
denotes |
RIP1 |
| T10204 |
23974-23978 |
Protein |
denotes |
bFGF |
| T10233 |
24000-24009 |
Positive_regulation |
denotes |
induction |
| T10205 |
24013-24017 |
Protein |
denotes |
TNFα |
| T10235 |
24166-24178 |
Positive_regulation |
denotes |
upregulation |
| T10206 |
24182-24186 |
Protein |
denotes |
TNFα |
| T10237 |
24215-24224 |
Positive_regulation |
denotes |
increased |
| T10234 |
24349-24357 |
Positive_regulation |
denotes |
increase |
| T10207 |
24371-24375 |
Protein |
denotes |
TNFα |
| T10236 |
24376-24385 |
Gene_expression |
denotes |
synthesis |
| T30869 |
24446-24453 |
Regulation |
denotes |
control |
| T30860 |
24464-24468 |
Protein |
denotes |
TNFα |
| T30868 |
24469-24478 |
Gene_expression |
denotes |
synthesis |
| T30861 |
24574-24578 |
Protein |
denotes |
bFGF |
| T30862 |
24654-24659 |
Protein |
denotes |
mTNFα |
| T30863 |
24690-24693 |
Protein |
denotes |
18S |
| T30864 |
24742-24746 |
Protein |
denotes |
TNFα |
| T30865 |
24848-24852 |
Protein |
denotes |
TNFα |
| T30870 |
24858-24864 |
Transcription |
denotes |
levels |
| T30866 |
24973-24977 |
Protein |
denotes |
TNFα |
| T30867 |
25020-25025 |
Protein |
denotes |
mTNFα |
| T10238 |
25146-25156 |
Positive_regulation |
denotes |
contribute |
| T10240 |
25164-25176 |
Positive_regulation |
denotes |
upregulation |
| T10208 |
25180-25184 |
Protein |
denotes |
TNFα |
| T10239 |
25279-25286 |
Negative_regulation |
denotes |
reduced |
| T10209 |
25287-25291 |
Protein |
denotes |
TNFα |
| T10241 |
25297-25303 |
Transcription |
denotes |
levels |
| T10210 |
25349-25353 |
Protein |
denotes |
RIP1 |
| T10244 |
25362-25372 |
Negative_regulation |
denotes |
inhibitors |
| T10242 |
25380-25386 |
Regulation |
denotes |
effect |
| T10211 |
25404-25408 |
Protein |
denotes |
TNFα |
| T10212 |
25463-25467 |
Protein |
denotes |
bFGF |
| T10243 |
25540-25547 |
Positive_regulation |
denotes |
mediate |
| T10246 |
25570-25578 |
Positive_regulation |
denotes |
increase |
| T10213 |
25582-25586 |
Protein |
denotes |
TNFα |
| T10245 |
25587-25596 |
Gene_expression |
denotes |
synthesis |
| T12165 |
25689-25698 |
Regulation |
denotes |
regulator |
| T12152 |
25702-25706 |
Protein |
denotes |
TNFα |
| T12164 |
25707-25716 |
Gene_expression |
denotes |
synthesis |
| T12167 |
25820-25825 |
Negative_regulation |
denotes |
block |
| T12166 |
25830-25838 |
Positive_regulation |
denotes |
increase |
| T12153 |
25842-25846 |
Protein |
denotes |
TNFα |
| T12172 |
25927-25936 |
Negative_regulation |
denotes |
Knockdown |
| T12154 |
25953-25957 |
Protein |
denotes |
Akt1 |
| T12155 |
25962-25966 |
Protein |
denotes |
Akt2 |
| T12169 |
25970-25980 |
Negative_regulation |
denotes |
inhibition |
| T12170 |
26000-26010 |
Negative_regulation |
denotes |
suppressed |
| T12156 |
26057-26062 |
Protein |
denotes |
c-Jun |
| T12168 |
26063-26078 |
Phosphorylation |
denotes |
phosphorylation |
| T12157 |
26143-26147 |
Protein |
denotes |
RIP1 |
| T12171 |
26156-26166 |
Positive_regulation |
denotes |
activation |
| T12176 |
26204-26213 |
Negative_regulation |
denotes |
inhibited |
| T12177 |
26218-26225 |
Negative_regulation |
denotes |
delayed |
| T12175 |
26246-26254 |
Positive_regulation |
denotes |
increase |
| T12158 |
26258-26262 |
Protein |
denotes |
bFGF |
| T12174 |
26272-26279 |
Positive_regulation |
denotes |
induced |
| T12159 |
26288-26293 |
Protein |
denotes |
c-Jun |
| T12173 |
26294-26309 |
Phosphorylation |
denotes |
phosphorylation |
| T12178 |
26322-26331 |
Negative_regulation |
denotes |
Knockdown |
| T12161 |
26359-26365 |
Protein |
denotes |
p70S6K |
| T12181 |
26392-26402 |
Negative_regulation |
denotes |
attenuated |
| T12179 |
26430-26438 |
Positive_regulation |
denotes |
increase |
| T12160 |
26450-26455 |
Protein |
denotes |
c-Jun |
| T12180 |
26456-26471 |
Phosphorylation |
denotes |
phosphorylation |
| T12162 |
26550-26553 |
Protein |
denotes |
S6K |
| T12163 |
26583-26587 |
Protein |
denotes |
RIP1 |
| T13158 |
26691-26695 |
Protein |
denotes |
PDK1 |
| T13165 |
27044-27058 |
Phosphorylation |
denotes |
phosphorylated |
| T13159 |
27083-27128 |
Protein |
denotes |
3-phosphoinositide dependent protein kinase-1 |
| T13160 |
27130-27134 |
Protein |
denotes |
PDK1 |
| T13161 |
27333-27337 |
Protein |
denotes |
PDK1 |
| T13166 |
27339-27349 |
Negative_regulation |
denotes |
Inhibition |
| T13162 |
27362-27366 |
Protein |
denotes |
PDK1 |
| T13168 |
27533-27542 |
Negative_regulation |
denotes |
knockdown |
| T13163 |
27546-27550 |
Protein |
denotes |
PDK1 |
| T13164 |
27652-27656 |
Protein |
denotes |
PDK1 |
| T13167 |
27675-27683 |
Positive_regulation |
denotes |
required |
| T14957 |
27853-27863 |
Gene_expression |
denotes |
expressing |
| T14914 |
27896-27900 |
Protein |
denotes |
Akt1 |
| T14915 |
27902-27909 |
Protein |
denotes |
Myr-Akt |
| T14916 |
27948-27953 |
Protein |
denotes |
K179M |
| T14917 |
28024-28028 |
Protein |
denotes |
RIP1 |
| T14918 |
28096-28100 |
Protein |
denotes |
Akt1 |
| T14919 |
28102-28109 |
Protein |
denotes |
Myr-Akt |
| T14958 |
28416-28426 |
Gene_expression |
denotes |
expressing |
| T14920 |
28427-28434 |
Protein |
denotes |
Myr-Akt |
| T14921 |
28713-28720 |
Protein |
denotes |
Myr-Akt |
| T14922 |
28734-28739 |
Protein |
denotes |
K179M |
| T14923 |
28826-28833 |
Protein |
denotes |
Myr-Akt |
| T14924 |
29030-29035 |
Protein |
denotes |
c-Jun |
| T14959 |
29036-29051 |
Phosphorylation |
denotes |
phosphorylation |
| T14960 |
29066-29078 |
Positive_regulation |
denotes |
upregulation |
| T14925 |
29082-29086 |
Protein |
denotes |
TNFα |
| T14926 |
29384-29388 |
Protein |
denotes |
RIP1 |
| T14927 |
29493-29497 |
Protein |
denotes |
RIP1 |
| T31430 |
30397-30401 |
Protein |
denotes |
TNFα |
| T31433 |
30407-30413 |
Transcription |
denotes |
levels |
| T31431 |
30468-30471 |
Protein |
denotes |
18S |
| T31432 |
30699-30703 |
Protein |
denotes |
TNFα |
| T14929 |
30828-30835 |
Protein |
denotes |
Myr-Akt |
| T14961 |
30855-30864 |
Positive_regulation |
denotes |
increased |
| T14930 |
30865-30872 |
Protein |
denotes |
Myr-Akt |
| T14965 |
30986-30995 |
Positive_regulation |
denotes |
increased |
| T14964 |
31005-31015 |
Gene_expression |
denotes |
expression |
| T14931 |
31019-31026 |
Protein |
denotes |
Myr-Akt |
| T14932 |
31040-31045 |
Protein |
denotes |
K179M |
| T14966 |
31204-31213 |
Positive_regulation |
denotes |
increased |
| T14933 |
31232-31239 |
Protein |
denotes |
Myr-Akt |
| T14934 |
31268-31274 |
Protein |
denotes |
p70S6K |
| T14935 |
31276-31278 |
Protein |
denotes |
S6 |
| T14936 |
31290-31295 |
Protein |
denotes |
FoxO4 |
| T14967 |
31308-31322 |
Phosphorylation |
denotes |
phosphorylated |
| T14969 |
31375-31390 |
Phosphorylation |
denotes |
phosphorylation |
| T14937 |
31394-31399 |
Protein |
denotes |
FoxO1 |
| T14938 |
31404-31408 |
Protein |
denotes |
MDM2 |
| T14968 |
31427-31436 |
Positive_regulation |
denotes |
increased |
| T14970 |
31501-31516 |
Phosphorylation |
denotes |
phosphorylation |
| T14939 |
31520-31527 |
Protein |
denotes |
Myr-Akt |
| T14940 |
31653-31657 |
Protein |
denotes |
TNFα |
| T14971 |
31658-31668 |
Gene_expression |
denotes |
production |
| T14972 |
31697-31706 |
Gene_expression |
denotes |
expressed |
| T14941 |
31707-31714 |
Protein |
denotes |
Myr-Akt |
| T14973 |
32276-32285 |
Negative_regulation |
denotes |
reduction |
| T14942 |
32315-32318 |
Protein |
denotes |
Akt |
| T14943 |
32771-32783 |
Protein |
denotes |
S473D mutant |
| T14974 |
32795-32809 |
Phosphorylation |
denotes |
phosphorylated |
| T14944 |
32896-32901 |
Protein |
denotes |
S473A |
| T14975 |
32925-32931 |
Gene_expression |
denotes |
active |
| T14945 |
32963-32968 |
Protein |
denotes |
S473A |
| T14976 |
32998-33012 |
Phosphorylation |
denotes |
phosphorylated |
| T14946 |
33133-33137 |
Protein |
denotes |
PDK1 |
| T14977 |
33249-33258 |
Positive_regulation |
denotes |
promoting |
| T14978 |
33271-33286 |
Phosphorylation |
denotes |
phosphorylation |
| T14947 |
33298-33303 |
Protein |
denotes |
c-Jun |
| T14948 |
33309-33313 |
Protein |
denotes |
TNFα |
| T14949 |
33339-33344 |
Protein |
denotes |
T308D |
| T14979 |
33419-33434 |
Phosphorylation |
denotes |
phosphorylation |
| T14950 |
33583-33588 |
Protein |
denotes |
T308D |
| T14980 |
33668-33682 |
Phosphorylation |
denotes |
phosphorylated |
| T14951 |
33690-33697 |
Protein |
denotes |
Myr-Akt |
| T14981 |
33727-33731 |
Negative_regulation |
denotes |
zVAD |
| T14952 |
33742-33747 |
Protein |
denotes |
FoxO1 |
| T14953 |
33749-33754 |
Protein |
denotes |
Foxo4 |
| T14954 |
33756-33760 |
Protein |
denotes |
MDM2 |
| T14955 |
33766-33772 |
Protein |
denotes |
p70S6K |
| T14982 |
34004-34011 |
Positive_regulation |
denotes |
promote |
| T14956 |
34012-34016 |
Protein |
denotes |
TNFα |
| T14983 |
34017-34026 |
Gene_expression |
denotes |
synthesis |
| T17359 |
34073-34081 |
Regulation |
denotes |
Controls |
| T17340 |
34082-34086 |
Protein |
denotes |
TNFα |
| T17360 |
34087-34097 |
Gene_expression |
denotes |
Production |
| T17341 |
34149-34153 |
Protein |
denotes |
RIP1 |
| T17342 |
34303-34343 |
Protein |
denotes |
Fas-associated protein with death domain |
| T17343 |
34345-34349 |
Protein |
denotes |
FADD |
| T17344 |
34509-34513 |
Protein |
denotes |
TNFα |
| T17345 |
34571-34575 |
Protein |
denotes |
RIP1 |
| T17346 |
34718-34722 |
Protein |
denotes |
TNFα |
| T17364 |
34728-34734 |
Transcription |
denotes |
levels |
| T17362 |
34740-34749 |
Positive_regulation |
denotes |
increased |
| T17363 |
34813-34822 |
Negative_regulation |
denotes |
inhibited |
| T17347 |
34831-34835 |
Protein |
denotes |
RIP1 |
| T17361 |
34844-34854 |
Negative_regulation |
denotes |
inhibitors |
| T17365 |
34980-34990 |
Regulation |
denotes |
regulation |
| T17349 |
35004-35008 |
Protein |
denotes |
TNFα |
| T17366 |
35009-35018 |
Gene_expression |
denotes |
synthesis |
| T17348 |
35131-35135 |
Protein |
denotes |
RIP1 |
| T32121 |
35268-35279 |
Positive_regulation |
denotes |
contributes |
| T32108 |
35293-35297 |
Protein |
denotes |
TNFα |
| T32120 |
35298-35308 |
Gene_expression |
denotes |
production |
| T32109 |
35333-35337 |
Protein |
denotes |
FADD |
| T32123 |
35338-35347 |
Negative_regulation |
denotes |
deficient |
| T32110 |
35379-35383 |
Protein |
denotes |
TNFα |
| T32111 |
35421-35425 |
Protein |
denotes |
TNFα |
| T32122 |
35431-35437 |
Transcription |
denotes |
levels |
| T32112 |
35476-35479 |
Protein |
denotes |
18S |
| T32113 |
35631-35635 |
Protein |
denotes |
TNFα |
| T32114 |
35785-35789 |
Protein |
denotes |
TNFα |
| T32115 |
35817-35821 |
Protein |
denotes |
TNFα |
| T32124 |
35881-35891 |
Gene_expression |
denotes |
expressing |
| T32119 |
35908-35912 |
Protein |
denotes |
Akt1 |
| T32116 |
35916-35920 |
Protein |
denotes |
Akt2 |
| T32117 |
35952-35956 |
Protein |
denotes |
TNFα |
| T32118 |
35984-35988 |
Protein |
denotes |
TNFα |
| T17350 |
36243-36247 |
Protein |
denotes |
TNFα |
| T17367 |
36326-36334 |
Positive_regulation |
denotes |
restored |
| T17351 |
36335-36339 |
Protein |
denotes |
TNFα |
| T17368 |
36345-36355 |
Transcription |
denotes |
production |
| T17352 |
36371-36375 |
Protein |
denotes |
TNFα |
| T17370 |
36511-36521 |
Gene_expression |
denotes |
expressing |
| T17353 |
36533-36537 |
Protein |
denotes |
Akt1 |
| T17354 |
36541-36545 |
Protein |
denotes |
Akt2 |
| T17355 |
36591-36595 |
Protein |
denotes |
TNFα |
| T17356 |
36645-36649 |
Protein |
denotes |
RIP1 |
| T17371 |
36650-36659 |
Positive_regulation |
denotes |
dependent |
| T17357 |
36660-36664 |
Protein |
denotes |
TNFα |
| T17369 |
36670-36682 |
Positive_regulation |
denotes |
upregulation |
| T17358 |
36814-36818 |
Protein |
denotes |
TNFα |
| T17372 |
36819-36828 |
Gene_expression |
denotes |
synthesis |
| T19268 |
37024-37028 |
Protein |
denotes |
RIP1 |
| T19269 |
37118-37122 |
Protein |
denotes |
RIP1 |
| T19270 |
37374-37378 |
Protein |
denotes |
RIP1 |
| T19294 |
37686-37696 |
Gene_expression |
denotes |
Expression |
| T19271 |
37750-37757 |
Protein |
denotes |
Myr-Akt |
| T19296 |
37823-37833 |
Gene_expression |
denotes |
expression |
| T19272 |
37837-37844 |
Protein |
denotes |
Myr-Akt |
| T19295 |
37858-37868 |
Positive_regulation |
denotes |
sufficient |
| T19273 |
37913-37917 |
Protein |
denotes |
RIP1 |
| T32403 |
38138-38142 |
Protein |
denotes |
RIP1 |
| T32404 |
38297-38301 |
Protein |
denotes |
RIP1 |
| T32406 |
38346-38351 |
Positive_regulation |
denotes |
leads |
| T32405 |
38355-38359 |
Protein |
denotes |
TNFα |
| T32407 |
38360-38369 |
Gene_expression |
denotes |
synthesis |
| T19274 |
39170-39174 |
Protein |
denotes |
RIP1 |
| T19275 |
39297-39301 |
Protein |
denotes |
TNFα |
| T19297 |
39302-39311 |
Gene_expression |
denotes |
synthesis |
| T19299 |
39569-39578 |
Negative_regulation |
denotes |
inhibited |
| T19276 |
39579-39583 |
Protein |
denotes |
TNFα |
| T19298 |
39584-39594 |
Gene_expression |
denotes |
production |
| T19300 |
39808-39815 |
Negative_regulation |
denotes |
inhibit |
| T19277 |
39820-39833 |
Protein |
denotes |
p110δ subunit |
| T19278 |
39851-39855 |
Protein |
denotes |
PDK1 |
| T19279 |
40119-40123 |
Protein |
denotes |
JNK1 |
| T19280 |
40128-40132 |
Protein |
denotes |
JNK2 |
| T19302 |
40170-40180 |
Negative_regulation |
denotes |
inhibition |
| T19301 |
40184-40193 |
Negative_regulation |
denotes |
knockdown |
| T19281 |
40197-40201 |
Protein |
denotes |
JNK1 |
| T19282 |
40202-40203 |
Protein |
denotes |
2 |
| T19303 |
40251-40261 |
Negative_regulation |
denotes |
inhibiting |
| T19304 |
40266-40281 |
Phosphorylation |
denotes |
phosphorylation |
| T19283 |
40285-40290 |
Protein |
denotes |
c-Jun |
| T19306 |
40371-40380 |
Negative_regulation |
denotes |
reduction |
| T19284 |
40384-40388 |
Protein |
denotes |
TNFα |
| T19305 |
40389-40399 |
Gene_expression |
denotes |
production |
| T19307 |
40618-40622 |
Positive_regulation |
denotes |
role |
| T19285 |
40627-40632 |
Protein |
denotes |
c-Jun |
| T19286 |
40662-40666 |
Protein |
denotes |
TNFα |
| T19308 |
40667-40676 |
Gene_expression |
denotes |
synthesis |
| T19287 |
40735-40740 |
Protein |
denotes |
c-Jun |
| T19309 |
40747-40756 |
Negative_regulation |
denotes |
knockdown |
| T19288 |
40882-40886 |
Protein |
denotes |
TNFα |
| T19310 |
40887-40897 |
Gene_expression |
denotes |
production |
| T19311 |
40899-40908 |
Regulation |
denotes |
dependent |
| T19289 |
40912-40917 |
Protein |
denotes |
c-Jun |
| T19312 |
41054-41062 |
Positive_regulation |
denotes |
increase |
| T19290 |
41087-41092 |
Protein |
denotes |
c-Jun |
| T19291 |
41140-41144 |
Protein |
denotes |
TNFα |
| T19292 |
41267-41272 |
Protein |
denotes |
c-Jun |
| T19313 |
41407-41422 |
Phosphorylation |
denotes |
phosphorylation |
| T19293 |
41426-41431 |
Protein |
denotes |
c-Jun |
| T22751 |
41723-41727 |
Protein |
denotes |
RIP1 |
| T22752 |
41867-41871 |
Protein |
denotes |
RIP1 |
| T22753 |
41994-41998 |
Protein |
denotes |
TNFα |
| T22792 |
41999-42008 |
Gene_expression |
denotes |
synthesis |
| T22794 |
42215-42225 |
Gene_expression |
denotes |
Expression |
| T22793 |
42251-42268 |
Positive_regulation |
denotes |
membrane-targeted |
| T22754 |
42269-42276 |
Protein |
denotes |
Myr-Akt |
| T22798 |
42323-42333 |
Gene_expression |
denotes |
expression |
| T22755 |
42337-42344 |
Protein |
denotes |
Myr-Akt |
| T22797 |
42352-42362 |
Positive_regulation |
denotes |
sufficient |
| T22795 |
42409-42419 |
Positive_regulation |
denotes |
activation |
| T22756 |
42431-42435 |
Protein |
denotes |
TNFα |
| T22796 |
42436-42445 |
Gene_expression |
denotes |
synthesis |
| T22757 |
42457-42461 |
Protein |
denotes |
RIP1 |
| T22758 |
43036-43040 |
Protein |
denotes |
RIP1 |
| T22759 |
43115-43119 |
Protein |
denotes |
RIP1 |
| T22760 |
43486-43490 |
Protein |
denotes |
RIP1 |
| T22761 |
43508-43512 |
Protein |
denotes |
PDK1 |
| T22762 |
43645-43649 |
Protein |
denotes |
RIP1 |
| T22763 |
43762-43769 |
Protein |
denotes |
Myr-Akt |
| T22799 |
44068-44083 |
Phosphorylation |
denotes |
phosphorylation |
| T22764 |
44094-44098 |
Protein |
denotes |
RIP1 |
| T22801 |
44230-44237 |
Positive_regulation |
denotes |
promote |
| T22765 |
44257-44261 |
Protein |
denotes |
TNFα |
| T22800 |
44262-44271 |
Gene_expression |
denotes |
synthesis |
| T22766 |
44983-44987 |
Protein |
denotes |
TNFα |
| T22767 |
45130-45134 |
Protein |
denotes |
TNFα |
| T22768 |
45456-45460 |
Protein |
denotes |
RIP1 |
| T22769 |
45667-45672 |
Protein |
denotes |
FoxO1 |
| T22770 |
45673-45674 |
Protein |
denotes |
4 |
| T22771 |
45680-45684 |
Protein |
denotes |
MDM2 |
| T22772 |
46185-46189 |
Protein |
denotes |
RIP1 |
| T22802 |
46198-46208 |
Gene_expression |
denotes |
expression |
| T22773 |
46851-46855 |
Protein |
denotes |
TNFα |
| T22774 |
46979-46983 |
Protein |
denotes |
TNFα |
| T22775 |
47343-47347 |
Protein |
denotes |
RIP1 |
| T22776 |
47593-47597 |
Protein |
denotes |
FADD |
| T22805 |
47598-47607 |
Negative_regulation |
denotes |
deficient |
| T22803 |
47688-47696 |
Positive_regulation |
denotes |
increase |
| T22777 |
47700-47704 |
Protein |
denotes |
TNFα |
| T22804 |
47705-47714 |
Gene_expression |
denotes |
synthesis |
| T22778 |
47861-47865 |
Protein |
denotes |
RIP1 |
| T22806 |
47893-47902 |
Positive_regulation |
denotes |
mediating |
| T22807 |
47907-47917 |
Gene_expression |
denotes |
production |
| T22779 |
47921-47925 |
Protein |
denotes |
TNFα |
| T22808 |
48673-48683 |
Positive_regulation |
denotes |
activation |
| T22780 |
48687-48691 |
Protein |
denotes |
TNFα |
| T22809 |
48692-48701 |
Gene_expression |
denotes |
synthesis |
| T22781 |
48705-48709 |
Protein |
denotes |
RIP1 |
| T22812 |
48928-48932 |
Negative_regulation |
denotes |
loss |
| T22810 |
48936-48943 |
Regulation |
denotes |
control |
| T22782 |
48949-48953 |
Protein |
denotes |
RIP1 |
| T22783 |
48954-48958 |
Protein |
denotes |
RIP3 |
| T22784 |
48980-48984 |
Protein |
denotes |
FADD |
| T22785 |
48989-48998 |
Protein |
denotes |
caspase-8 |
| T22786 |
49069-49073 |
Protein |
denotes |
TNFα |
| T22811 |
49074-49084 |
Gene_expression |
denotes |
production |
| T22814 |
49213-49222 |
Positive_regulation |
denotes |
increased |
| T22813 |
49223-49233 |
Gene_expression |
denotes |
production |
| T22787 |
49237-49241 |
Protein |
denotes |
TNFα |
| T22788 |
49582-49586 |
Protein |
denotes |
RIP1 |
| T22789 |
49591-49595 |
Protein |
denotes |
RIP3 |
| T22790 |
49672-49676 |
Protein |
denotes |
RIP1 |
| T22791 |
49785-49789 |
Protein |
denotes |
RIP1 |
| T22815 |
49797-49807 |
Negative_regulation |
denotes |
inhibitors |
| T25250 |
50802-50806 |
Protein |
denotes |
TNFα |
| T25251 |
50825-50829 |
Protein |
denotes |
bFGF |
| T25252 |
50842-50845 |
Protein |
denotes |
EGF |
| T25253 |
50882-50887 |
Protein |
denotes |
IGF-1 |
| T25648 |
50989-50997 |
Protein |
denotes |
Myr-Akt1 |
| T25649 |
51056-51069 |
Protein |
denotes |
Myr-Akt1-FLAG |
| T25650 |
51201-51209 |
Protein |
denotes |
Myr-Akt1 |
| T26062 |
52217-52221 |
Protein |
denotes |
TNFα |
| T26063 |
52302-52305 |
Protein |
denotes |
18S |
| T26064 |
52392-52396 |
Protein |
denotes |
TNFα |
| T26065 |
52443-52447 |
Protein |
denotes |
TNFα |
| T26066 |
52493-52496 |
Protein |
denotes |
18S |
| T26067 |
52541-52544 |
Protein |
denotes |
18S |
| T26326 |
52603-52607 |
Protein |
denotes |
FADD |
| T26327 |
52608-52617 |
Negative_regulation |
denotes |
deficient |
| T26866 |
54009-54013 |
Protein |
denotes |
Akt1 |
| T26867 |
54035-54039 |
Protein |
denotes |
Akt2 |
| T26868 |
54061-54065 |
Protein |
denotes |
Akt3 |
| T26869 |
54113-54117 |
Protein |
denotes |
PDK1 |
| T26870 |
54176-54181 |
Protein |
denotes |
Mapk8 |
| T26871 |
54203-54208 |
Protein |
denotes |
Mapk9 |
| T26872 |
54402-54406 |
Protein |
denotes |
TNFα |
| T27317 |
54647-54651 |
Protein |
denotes |
TNFα |
| T27318 |
54806-54810 |
Protein |
denotes |
TNFα |
| T27858 |
56096-56104 |
Protein |
denotes |
Myr-Akt1 |
| T28217 |
57079-57083 |
Protein |
denotes |
TNFα |
| T28218 |
57096-57100 |
Protein |
denotes |
TNFα |
| T28362 |
57427-57434 |
Protein |
denotes |
Myr-Akt |
| T28363 |
57439-57457 |
Binding |
denotes |
immunoprecipitated |
| R11566 |
T17340 |
T17360 |
themeOf |
TNFα,Production |
| R11567 |
T17346 |
T17363 |
themeOf |
TNFα,inhibited |
| R11568 |
T17346 |
T17364 |
themeOf |
TNFα,levels |
| R11569 |
T17346 |
T17362 |
themeOf |
TNFα,increased |
| R11570 |
T17347 |
T17361 |
themeOf |
RIP1,inhibitors |
| R11571 |
T17349 |
T17366 |
themeOf |
TNFα,synthesis |
| R11572 |
T17351 |
T17368 |
themeOf |
TNFα,production |
| R11573 |
T17353 |
T17370 |
themeOf |
Akt1,expressing |
| R11574 |
T17354 |
T17370 |
themeOf |
Akt2,expressing |
| R11575 |
T17357 |
T17369 |
themeOf |
TNFα,upregulation |
| R11576 |
T17358 |
T17372 |
themeOf |
TNFα,synthesis |
| R11577 |
T17360 |
T17359 |
themeOf |
Production,Controls |
| R11578 |
T17366 |
T17365 |
themeOf |
synthesis,regulation |
| R11579 |
T17368 |
T17367 |
themeOf |
production,restored |
| R11580 |
T17369 |
T17371 |
themeOf |
upregulation,dependent |
| R1200 |
T1751 |
T1769 |
themeOf |
RIP3,complex |
| R1201 |
T1756 |
T1770 |
themeOf |
TNFα,synthesis |
| R1202 |
T1758 |
T1771 |
themeOf |
TNFα,production |
| R1203 |
T1763 |
T1773 |
themeOf |
RIP1,phosphorylation |
| R1204 |
T1765 |
T1775 |
themeOf |
TNFα,production |
| R1205 |
T1768 |
T1777 |
themeOf |
TNFα,production |
| R1206 |
T1773 |
T1772 |
themeOf |
phosphorylation,activated |
| R1207 |
T1773 |
T1774 |
themeOf |
phosphorylation,kinase-dependent |
| R1208 |
T1775 |
T1776 |
themeOf |
production,activation |
| R12906 |
T19271 |
T19294 |
themeOf |
Myr-Akt,Expression |
| R12907 |
T19272 |
T19296 |
themeOf |
Myr-Akt,expression |
| R12908 |
T19275 |
T19297 |
themeOf |
TNFα,synthesis |
| R12909 |
T19276 |
T19298 |
themeOf |
TNFα,production |
| R12910 |
T19277 |
T19300 |
themeOf |
p110δ subunit,inhibit |
| R12911 |
T19281 |
T19302 |
themeOf |
JNK1,inhibition |
| R12912 |
T19281 |
T19301 |
themeOf |
JNK1,knockdown |
| R12913 |
T19282 |
T19302 |
themeOf |
2,inhibition |
| R12914 |
T19282 |
T19301 |
themeOf |
2,knockdown |
| R12915 |
T19283 |
T19304 |
themeOf |
c-Jun,phosphorylation |
| R12916 |
T19284 |
T19305 |
themeOf |
TNFα,production |
| R12917 |
T19285 |
T19307 |
causeOf |
c-Jun,role |
| R12918 |
T19286 |
T19308 |
themeOf |
TNFα,synthesis |
| R12919 |
T19287 |
T19309 |
themeOf |
c-Jun,knockdown |
| R12920 |
T19288 |
T19310 |
themeOf |
TNFα,production |
| R12921 |
T19289 |
T19311 |
causeOf |
c-Jun,dependent |
| R12922 |
T19290 |
T19312 |
themeOf |
c-Jun,increase |
| R12923 |
T19293 |
T19313 |
themeOf |
c-Jun,phosphorylation |
| R12924 |
T19296 |
T19295 |
themeOf |
expression,sufficient |
| R12925 |
T19298 |
T19299 |
themeOf |
production,inhibited |
| R12926 |
T19302 |
T19301 |
themeOf |
inhibition,knockdown |
| R12927 |
T19302 |
T19301 |
themeOf |
inhibition,knockdown |
| R12928 |
T19304 |
T19303 |
themeOf |
phosphorylation,inhibiting |
| R12929 |
T19305 |
T19306 |
themeOf |
production,reduction |
| R12930 |
T19308 |
T19307 |
themeOf |
synthesis,role |
| R12931 |
T19310 |
T19311 |
themeOf |
production,dependent |
| R15381 |
T22753 |
T22792 |
themeOf |
TNFα,synthesis |
| R15382 |
T22754 |
T22794 |
themeOf |
Myr-Akt,Expression |
| R15383 |
T22754 |
T22793 |
themeOf |
Myr-Akt,membrane-targeted |
| R15384 |
T22755 |
T22798 |
themeOf |
Myr-Akt,expression |
| R15385 |
T22756 |
T22796 |
themeOf |
TNFα,synthesis |
| R15386 |
T22764 |
T22799 |
themeOf |
RIP1,phosphorylation |
| R15387 |
T22765 |
T22800 |
themeOf |
TNFα,synthesis |
| R15388 |
T22772 |
T22802 |
themeOf |
RIP1,expression |
| R15389 |
T22776 |
T22805 |
themeOf |
FADD,deficient |
| R15390 |
T22777 |
T22804 |
themeOf |
TNFα,synthesis |
| R15391 |
T22779 |
T22807 |
themeOf |
TNFα,production |
| R15392 |
T22780 |
T22809 |
themeOf |
TNFα,synthesis |
| R15393 |
T22782 |
T22810 |
themeOf |
RIP1,control |
| R15394 |
T22783 |
T22812 |
themeOf |
RIP3,loss |
| R15395 |
T22783 |
T22810 |
themeOf |
RIP3,control |
| R15396 |
T22786 |
T22811 |
themeOf |
TNFα,production |
| R15397 |
T22787 |
T22813 |
themeOf |
TNFα,production |
| R15398 |
T22791 |
T22815 |
themeOf |
RIP1,inhibitors |
| R15399 |
T22796 |
T22795 |
themeOf |
synthesis,activation |
| R15400 |
T22798 |
T22797 |
themeOf |
expression,sufficient |
| R15401 |
T22800 |
T22801 |
themeOf |
synthesis,promote |
| R15402 |
T22804 |
T22803 |
themeOf |
synthesis,increase |
| R15403 |
T22807 |
T22806 |
themeOf |
production,mediating |
| R15404 |
T22809 |
T22808 |
themeOf |
synthesis,activation |
| R15405 |
T22813 |
T22814 |
themeOf |
production,increased |
| R18019 |
T26326 |
T26327 |
themeOf |
FADD,deficient |
| R19678 |
T28362 |
T28363 |
themeOf |
Myr-Akt,immunoprecipitated |
| R20182 |
T29102 |
T29106 |
themeOf |
Akt1,transfected |
| R20183 |
T29103 |
T29106 |
themeOf |
Akt2,transfected |
| R20184 |
T29104 |
T29106 |
themeOf |
Akt3 siRNAs,transfected |
| R20562 |
T29642 |
T29647 |
themeOf |
RIP1,phosphorylation |
| R20563 |
T29647 |
T29648 |
themeOf |
phosphorylation,kinase-dependent |
| R21353 |
T30860 |
T30868 |
themeOf |
TNFα,synthesis |
| R21354 |
T30865 |
T30870 |
themeOf |
TNFα,levels |
| R21355 |
T30868 |
T30869 |
themeOf |
synthesis,control |
| R21761 |
T31430 |
T31433 |
themeOf |
TNFα,levels |
| R22217 |
T32108 |
T32120 |
themeOf |
TNFα,production |
| R22218 |
T32109 |
T32123 |
themeOf |
FADD,deficient |
| R22219 |
T32111 |
T32122 |
themeOf |
TNFα,levels |
| R22220 |
T32116 |
T32124 |
themeOf |
Akt2,expressing |
| R22221 |
T32119 |
T32124 |
themeOf |
Akt1,expressing |
| R22222 |
T32120 |
T32121 |
themeOf |
production,contributes |
| R22323 |
T32405 |
T32407 |
themeOf |
TNFα,synthesis |
| R22324 |
T32407 |
T32406 |
themeOf |
synthesis,leads |
| R2718 |
T3919 |
T3946 |
themeOf |
caspase-8,inhibition |
| R2719 |
T3920 |
T3947 |
themeOf |
caspase-8,loss |
| R2720 |
T3925 |
T3948 |
themeOf |
CYLD,inactivates |
| R2721 |
T3933 |
T3949 |
themeOf |
RIP1,inhibitor |
| R2722 |
T3936 |
T3950 |
themeOf |
RIP1,loss |
| R2723 |
T3941 |
T3951 |
themeOf |
bFGF receptor tyrosine kinase,inhibitors |
| R2724 |
T3943 |
T3952 |
themeOf |
bFGF receptor,inhibitor |
| R4400 |
T6385 |
T6413 |
themeOf |
Akt1,knockdown |
| R4401 |
T6386 |
T6413 |
themeOf |
Akt2,knockdown |
| R4402 |
T6388 |
T6414 |
themeOf |
Akt3,expression |
| R4403 |
T6392 |
T6415 |
themeOf |
p46,phosphorylation |
| R4404 |
T6393 |
T6415 |
themeOf |
p54,phosphorylation |
| R4405 |
T6394 |
T6415 |
themeOf |
c-Jun,phosphorylation |
| R4406 |
T6394 |
T6416 |
themeOf |
c-Jun,increase |
| R4407 |
T6395 |
T6420 |
themeOf |
RIP1,inhibitor |
| R4408 |
T6396 |
T6418 |
themeOf |
Akt,phosphorylation |
| R4409 |
T6398 |
T6421 |
themeOf |
c-Jun,changes |
| R4410 |
T6399 |
T6422 |
themeOf |
c-Jun,increase |
| R4411 |
T6403 |
T6423 |
themeOf |
c-Jun,increase |
| R4412 |
T6406 |
T6424 |
themeOf |
c-Jun,phosphorylation |
| R4413 |
T6409 |
T6425 |
themeOf |
bFGF,increase |
| R4414 |
T6410 |
T6426 |
themeOf |
RIP1,dependent |
| R4415 |
T6415 |
T6416 |
themeOf |
phosphorylation,increase |
| R4416 |
T6415 |
T6416 |
themeOf |
phosphorylation,increase |
| R4417 |
T6415 |
T6416 |
themeOf |
phosphorylation,increase |
| R4418 |
T6418 |
T6419 |
themeOf |
phosphorylation,increase |
| R4419 |
T6419 |
T6417 |
themeOf |
increase,prevented |
| R4420 |
T6424 |
T6427 |
themeOf |
phosphorylation,increase |
| R4421 |
T6425 |
T6428 |
themeOf |
increase,blocked |
| R450 |
T353 |
T364 |
themeOf |
TNFα,Synthesis |
| R451 |
T354 |
T365 |
themeOf |
RIP1,Activation |
| R452 |
T357 |
T367 |
themeOf |
TNFα,production |
| R453 |
T360 |
T368 |
themeOf |
RIP1,links |
| R454 |
T362 |
T369 |
themeOf |
TNFα,production |
| R455 |
T364 |
T363 |
themeOf |
Synthesis,Regulates |
| R456 |
T367 |
T366 |
themeOf |
production,role |
| R4988 |
T7672 |
T7681 |
themeOf |
TNFα,induced |
| R4989 |
T7677 |
T7682 |
themeOf |
c-Jun,phosphorylation |
| R4990 |
T7682 |
T7683 |
themeOf |
phosphorylation,increase |
| R5493 |
T8426 |
T8431 |
themeOf |
RIP1,increase |
| R6659 |
T10172 |
T10214 |
themeOf |
double minute 2,phosphorylation |
| R6660 |
T10173 |
T10214 |
themeOf |
MDM2,phosphorylation |
| R6661 |
T10174 |
T10214 |
themeOf |
p70 ribosomal protein S6 Kinase,phosphorylation |
| R6662 |
T10175 |
T10214 |
themeOf |
p70S6K,phosphorylation |
| R6663 |
T10176 |
T10214 |
themeOf |
S6,phosphorylation |
| R6664 |
T10178 |
T10216 |
themeOf |
FoxO4,increase |
| R6665 |
T10185 |
T10217 |
themeOf |
pFoxO1,increase |
| R6666 |
T10187 |
T10218 |
themeOf |
Raptor,inhibitor |
| R6667 |
T10189 |
T10219 |
themeOf |
p70S6 kinase,activation |
| R6668 |
T10191 |
T10222 |
themeOf |
p70S6K,inhibitor |
| R6669 |
T10192 |
T10221 |
themeOf |
S6,phosphorylation |
| R6670 |
T10193 |
T10223 |
themeOf |
S6,knockdown |
| R6671 |
T10197 |
T10224 |
themeOf |
TNFα,upregulation |
| R6672 |
T10198 |
T10227 |
themeOf |
TNFα,synthesis |
| R6673 |
T10199 |
T10229 |
themeOf |
TNFα,synthesis |
| R6674 |
T10201 |
T10230 |
themeOf |
TNFα,increase |
| R6675 |
T10202 |
T10231 |
themeOf |
TNFα,levels |
| R6676 |
T10202 |
T10232 |
themeOf |
TNFα,increased |
| R6677 |
T10203 |
T10232 |
themeOf |
RIP1,increased |
| R6678 |
T10205 |
T10233 |
themeOf |
TNFα,induction |
| R6679 |
T10206 |
T10235 |
themeOf |
TNFα,upregulation |
| R6680 |
T10207 |
T10236 |
themeOf |
TNFα,synthesis |
| R6681 |
T10208 |
T10240 |
themeOf |
TNFα,upregulation |
| R6682 |
T10209 |
T10239 |
themeOf |
TNFα,reduced |
| R6683 |
T10209 |
T10241 |
themeOf |
TNFα,levels |
| R6684 |
T10210 |
T10244 |
themeOf |
RIP1,inhibitors |
| R6685 |
T10211 |
T10242 |
themeOf |
TNFα,effect |
| R6686 |
T10213 |
T10245 |
themeOf |
TNFα,synthesis |
| R6687 |
T10214 |
T10215 |
themeOf |
phosphorylation,increase |
| R6688 |
T10214 |
T10215 |
themeOf |
phosphorylation,increase |
| R6689 |
T10214 |
T10215 |
themeOf |
phosphorylation,increase |
| R6690 |
T10214 |
T10215 |
themeOf |
phosphorylation,increase |
| R6691 |
T10214 |
T10215 |
themeOf |
phosphorylation,increase |
| R6692 |
T10221 |
T10220 |
themeOf |
phosphorylation,block |
| R6693 |
T10224 |
T10225 |
themeOf |
upregulation,control |
| R6694 |
T10227 |
T10226 |
themeOf |
synthesis,increased |
| R6695 |
T10229 |
T10228 |
themeOf |
synthesis,contribute |
| R6696 |
T10235 |
T10237 |
themeOf |
upregulation,increased |
| R6697 |
T10236 |
T10234 |
themeOf |
synthesis,increase |
| R6698 |
T10240 |
T10238 |
themeOf |
upregulation,contribute |
| R6699 |
T10245 |
T10246 |
themeOf |
synthesis,increase |
| R6700 |
T10246 |
T10243 |
themeOf |
increase,mediate |
| R8007 |
T12152 |
T12164 |
themeOf |
TNFα,synthesis |
| R8008 |
T12153 |
T12166 |
themeOf |
TNFα,increase |
| R8009 |
T12154 |
T12169 |
themeOf |
Akt1,inhibition |
| R8010 |
T12154 |
T12172 |
themeOf |
Akt1,Knockdown |
| R8011 |
T12155 |
T12169 |
themeOf |
Akt2,inhibition |
| R8012 |
T12155 |
T12172 |
themeOf |
Akt2,Knockdown |
| R8013 |
T12156 |
T12168 |
themeOf |
c-Jun,phosphorylation |
| R8014 |
T12157 |
T12171 |
themeOf |
RIP1,activation |
| R8015 |
T12158 |
T12175 |
themeOf |
bFGF,increase |
| R8016 |
T12159 |
T12173 |
themeOf |
c-Jun,phosphorylation |
| R8017 |
T12160 |
T12180 |
themeOf |
c-Jun,phosphorylation |
| R8018 |
T12161 |
T12178 |
themeOf |
p70S6K,Knockdown |
| R8019 |
T12164 |
T12165 |
themeOf |
synthesis,regulator |
| R8020 |
T12166 |
T12167 |
themeOf |
increase,block |
| R8021 |
T12168 |
T12170 |
themeOf |
phosphorylation,suppressed |
| R8022 |
T12173 |
T12174 |
themeOf |
phosphorylation,induced |
| R8023 |
T12175 |
T12177 |
themeOf |
increase,delayed |
| R8024 |
T12175 |
T12176 |
themeOf |
increase,inhibited |
| R8025 |
T12179 |
T12181 |
themeOf |
increase,attenuated |
| R8026 |
T12180 |
T12179 |
themeOf |
phosphorylation,increase |
| R8752 |
T13160 |
T13165 |
themeOf |
PDK1,phosphorylated |
| R8753 |
T13162 |
T13166 |
themeOf |
PDK1,Inhibition |
| R8754 |
T13163 |
T13168 |
themeOf |
PDK1,knockdown |
| R8755 |
T13164 |
T13167 |
themeOf |
PDK1,required |
| R9911 |
T14914 |
T14957 |
themeOf |
Akt1,expressing |
| R9912 |
T14915 |
T14957 |
themeOf |
Myr-Akt,expressing |
| R9913 |
T14916 |
T14957 |
themeOf |
K179M,expressing |
| R9914 |
T14920 |
T14958 |
themeOf |
Myr-Akt,expressing |
| R9915 |
T14924 |
T14959 |
themeOf |
c-Jun,phosphorylation |
| R9916 |
T14925 |
T14960 |
themeOf |
TNFα,upregulation |
| R9917 |
T14928 |
T14963 |
themeOf |
RIP1,phosphorylation |
| R9918 |
T14929 |
T14963 |
themeOf |
Myr-Akt,phosphorylation |
| R9919 |
T14930 |
T14961 |
themeOf |
Myr-Akt,increased |
| R9920 |
T14931 |
T14964 |
themeOf |
Myr-Akt,expression |
| R9921 |
T14932 |
T14964 |
themeOf |
K179M,expression |
| R9922 |
T14933 |
T14966 |
themeOf |
Myr-Akt,increased |
| R9923 |
T14934 |
T14967 |
themeOf |
p70S6K,phosphorylated |
| R9924 |
T14935 |
T14967 |
themeOf |
S6,phosphorylated |
| R9925 |
T14936 |
T14967 |
themeOf |
FoxO4,phosphorylated |
| R9926 |
T14937 |
T14969 |
themeOf |
FoxO1,phosphorylation |
| R9927 |
T14938 |
T14969 |
themeOf |
MDM2,phosphorylation |
| R9928 |
T14939 |
T14970 |
themeOf |
Myr-Akt,phosphorylation |
| R9929 |
T14940 |
T14971 |
themeOf |
TNFα,production |
| R9930 |
T14941 |
T14972 |
themeOf |
Myr-Akt,expressed |
| R9931 |
T14942 |
T14973 |
themeOf |
Akt,reduction |
| R9932 |
T14943 |
T14974 |
themeOf |
S473D mutant,phosphorylated |
| R9933 |
T14944 |
T14975 |
themeOf |
S473A,active |
| R9934 |
T14945 |
T14976 |
themeOf |
S473A,phosphorylated |
| R9935 |
T14947 |
T14978 |
themeOf |
c-Jun,phosphorylation |
| R9936 |
T14948 |
T14977 |
themeOf |
TNFα,promoting |
| R9937 |
T14949 |
T14979 |
themeOf |
T308D,phosphorylation |
| R9938 |
T14953 |
T14980 |
themeOf |
Foxo4,phosphorylated |
| R9939 |
T14953 |
T14981 |
themeOf |
Foxo4,zVAD |
| R9940 |
T14956 |
T14983 |
themeOf |
TNFα,synthesis |
| R9941 |
T14963 |
T14962 |
themeOf |
phosphorylation,kinase-dependent |
| R9942 |
T14963 |
T14962 |
themeOf |
phosphorylation,kinase-dependent |
| R9943 |
T14964 |
T14965 |
themeOf |
expression,increased |
| R9944 |
T14964 |
T14965 |
themeOf |
expression,increased |
| R9945 |
T14969 |
T14968 |
themeOf |
phosphorylation,increased |
| R9946 |
T14969 |
T14968 |
themeOf |
phosphorylation,increased |
| R9947 |
T14978 |
T14977 |
themeOf |
phosphorylation,promoting |
| R9948 |
T14983 |
T14982 |
themeOf |
synthesis,promote |
