| Id |
Subject |
Object |
Predicate |
Lexical cue |
| BEL:20039336 |
733-993 |
kin(p(MGI:Rps6ka1)) increases p(MGI:Stk11,pmod(P,S,431)) |
denotes |
We present pharmacological and genetic evidence that p90(RSK) mediated this phosphorylation in response to agonists that activate ERK1/2 and that cAMP-dependent protein kinase mediated this phosphorylation in response to agonists that activate adenylate cyclas |
| BEL:20039468 |
1531-1756 |
kin(p(MGI:Stk11)) decreases bp(GOBP:"cell proliferation") |
denotes |
The reintroduction of wild-type LKB1 into a cancer cell line that lacks LKB1 suppressed growth, but mutants of LKB1 in which Ser(431) was mutated to Ala to prevent phosphorylation of LKB1 were ineffective in inhibiting growth |
| BEL:20016440 |
1531-1756 |
p(MGI:Stk11,pmod(P,S,431)) decreases bp(GOBP:"cell proliferation") |
denotes |
The reintroduction of wild-type LKB1 into a cancer cell line that lacks LKB1 suppressed growth, but mutants of LKB1 in which Ser(431) was mutated to Ala to prevent phosphorylation of LKB1 were ineffective in inhibiting growth |
| BEL:20016442 |
1531-1756 |
p(MGI:Stk11,pmod(P,S,431)) directlyIncreases kin(p(MGI:Stk11)) |
denotes |
The reintroduction of wild-type LKB1 into a cancer cell line that lacks LKB1 suppressed growth, but mutants of LKB1 in which Ser(431) was mutated to Ala to prevent phosphorylation of LKB1 were ineffective in inhibiting growth |
