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PubMed:9988768 JSONTXT

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ggdb-test

Id Subject Object Predicate Lexical cue
T1 356-361 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
T2 557-562 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
T3 597-604 https://acgg.asia/db/ggdb/info/gg015 denotes 3-OST-2
T4 597-602 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
T5 606-611 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
T6 620-625 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
T7 990-997 https://acgg.asia/db/ggdb/info/gg015 denotes 3-OST-2
T8 990-995 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
T9 999-1004 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
T10 1013-1018 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
T11 1220-1225 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
T12 1233-1238 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
T13 1338-1343 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
T14 1425-1432 https://acgg.asia/db/ggdb/info/gg015 denotes 3-OST-2
T15 1425-1430 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
T16 1437-1442 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
T17 1463-1470 https://acgg.asia/db/ggdb/info/gg015 denotes 3-OST-2
T18 1463-1468 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
T19 1475-1480 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
T20 1596-1603 https://acgg.asia/db/ggdb/info/gg015 denotes 3-OST-2
T21 1596-1601 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
T22 1656-1661 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST

GGDB-2020

Id Subject Object Predicate Lexical cue
T1 356-361 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
T2 557-562 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
T3 597-604 https://acgg.asia/db/ggdb/info/gg015 denotes 3-OST-2
T4 597-602 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
T5 606-611 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
T6 620-625 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
T7 990-997 https://acgg.asia/db/ggdb/info/gg015 denotes 3-OST-2
T8 990-995 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
T9 999-1004 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
T10 1013-1018 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
T11 1220-1225 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
T12 1233-1238 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
T13 1338-1343 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
T14 1425-1432 https://acgg.asia/db/ggdb/info/gg015 denotes 3-OST-2
T15 1425-1430 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
T16 1437-1442 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
T17 1463-1470 https://acgg.asia/db/ggdb/info/gg015 denotes 3-OST-2
T18 1463-1468 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
T19 1475-1480 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
T20 1596-1603 https://acgg.asia/db/ggdb/info/gg015 denotes 3-OST-2
T21 1596-1601 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
T22 1656-1661 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST

sentences

Id Subject Object Predicate Lexical cue
T1 0-113 Sentence denotes Expression of heparan sulfate D-glucosaminyl 3-O-sulfotransferase isoforms reveals novel substrate specificities.
T2 114-233 Sentence denotes The 3-O-sulfation of glucosamine residues is an important modification during the biosynthesis of heparan sulfate (HS).
T3 234-485 Sentence denotes Our previous studies have led us to purify and molecularly clone the heparan sulfate D-glucosaminyl 3-O-sulfotransferase (3-OST-1), which is the key enzyme converting nonanticoagulant heparan sulfate (HSinact) to anticoagulant heparan sulfate (HSact).
T4 486-680 Sentence denotes In this study, we expressed and characterized the full-length cDNAs of 3-OST-1 homologous genes, designated as 3-OST-2, 3-OST-3A, and 3-OST-3B as described in the accompanying paper (Shworak, N.
T5 681-704 Sentence denotes W., Liu, J., Petros, L.
T6 705-747 Sentence denotes M., Zhang, L., Kobayashi, M., Copeland, N.
T7 748-763 Sentence denotes G., Jenkins, N.
T8 764-785 Sentence denotes A., and Rosenberg, R.
T9 786-798 Sentence denotes D. (1999) J.
T10 799-804 Sentence denotes Biol.
T11 805-810 Sentence denotes Chem.
T12 811-827 Sentence denotes 274, 5170-5184).
T13 828-968 Sentence denotes All these cDNAs were successfully expressed in COS-7 cells, and heparan sulfate sulfotransferase activities were found in the cell extracts.
T14 969-1219 Sentence denotes We demonstrated that 3-OST-2, 3-OST-3A, and 3-OST-3B are heparan sulfate D-glucosaminyl 3-O-sulfotransferases because the enzymes transfer sulfate from adenosine 3'-phosphophate 5'-phospho-[35S]sulfate ([35S]PAPS) to the 3-OH position of glucosamine.
T15 1220-1276 Sentence denotes 3-OST-3A and 3-OST-3B sulfate an identical disaccharide.
T16 1277-1502 Sentence denotes HSact conversion activity in the cell extract transfected by 3-OST-1 was shown to be 300-fold greater than that in the cell extracts transfected by 3-OST-2 and 3-OST-3A, suggesting that 3-OST-2 and 3-OST-3A do not make HSact.
T17 1503-1699 Sentence denotes The results of the disaccharide analysis of the nitrous acid-degraded [35S]HS suggested that 3-OST-2 transfers sulfate to GlcA2S-GlcNS and IdoA2S-GlcNS; 3-OST-3A transfers sulfate to IdoA2S-GlcNS.
T18 1700-1876 Sentence denotes Our results demonstrate that the 3-O-sulfation of glucosamine is generated by different isoforms depending on the saccharide structures around the modified glucosamine residue.
T19 1877-2030 Sentence denotes This discovery has provided evidence for a new cellular mechanism for generating a defined saccharide sequence in structurally complex HS polysaccharide.

Glycosmos6-GlycoEpitope

Id Subject Object Predicate Lexical cue
T1 14-29 http://www.glycoepitope.jp/epitopes/EP0086 denotes heparan sulfate
T2 212-227 http://www.glycoepitope.jp/epitopes/EP0086 denotes heparan sulfate
T3 229-231 http://www.glycoepitope.jp/epitopes/EP0086 denotes HS
T4 303-318 http://www.glycoepitope.jp/epitopes/EP0086 denotes heparan sulfate
T5 418-433 http://www.glycoepitope.jp/epitopes/EP0086 denotes heparan sulfate
T6 461-476 http://www.glycoepitope.jp/epitopes/EP0086 denotes heparan sulfate
T7 892-907 http://www.glycoepitope.jp/epitopes/EP0086 denotes heparan sulfate
T8 1026-1041 http://www.glycoepitope.jp/epitopes/EP0086 denotes heparan sulfate
T9 1578-1580 http://www.glycoepitope.jp/epitopes/EP0086 denotes HS
T10 2012-2014 http://www.glycoepitope.jp/epitopes/EP0086 denotes HS

glycogenes

Id Subject Object Predicate Lexical cue
PD-GlycoGenes20190927-B_T1 356-361 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
PD-GlycoGenes20190927-B_T2 557-562 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
PD-GlycoGenes20190927-B_T3 583-593 url denotes designated
PD-GlycoGenes20190927-B_T4 597-604 https://acgg.asia/db/ggdb/info/gg015 denotes 3-OST-2
PD-GlycoGenes20190927-B_T5 597-602 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
PD-GlycoGenes20190927-B_T6 606-611 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
PD-GlycoGenes20190927-B_T7 620-625 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
PD-GlycoGenes20190927-B_T8 990-997 https://acgg.asia/db/ggdb/info/gg015 denotes 3-OST-2
PD-GlycoGenes20190927-B_T9 990-995 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
PD-GlycoGenes20190927-B_T10 999-1004 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
PD-GlycoGenes20190927-B_T11 1013-1018 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
PD-GlycoGenes20190927-B_T12 1220-1225 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
PD-GlycoGenes20190927-B_T13 1233-1238 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
PD-GlycoGenes20190927-B_T14 1338-1343 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
PD-GlycoGenes20190927-B_T15 1425-1432 https://acgg.asia/db/ggdb/info/gg015 denotes 3-OST-2
PD-GlycoGenes20190927-B_T16 1425-1430 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
PD-GlycoGenes20190927-B_T17 1437-1442 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
PD-GlycoGenes20190927-B_T18 1463-1470 https://acgg.asia/db/ggdb/info/gg015 denotes 3-OST-2
PD-GlycoGenes20190927-B_T19 1463-1468 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
PD-GlycoGenes20190927-B_T20 1475-1480 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
PD-GlycoGenes20190927-B_T21 1596-1603 https://acgg.asia/db/ggdb/info/gg015 denotes 3-OST-2
PD-GlycoGenes20190927-B_T22 1596-1601 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
PD-GlycoGenes20190927-B_T23 1656-1661 https://acgg.asia/db/ggdb/info/gg014 denotes 3-OST
PD-GlycoGenes20190927-B_T24 1892-1895 https://acgg.asia/db/ggdb/info/gg135 denotes has

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-113 Sentence denotes Expression of heparan sulfate D-glucosaminyl 3-O-sulfotransferase isoforms reveals novel substrate specificities.
T2 114-233 Sentence denotes The 3-O-sulfation of glucosamine residues is an important modification during the biosynthesis of heparan sulfate (HS).
T3 234-485 Sentence denotes Our previous studies have led us to purify and molecularly clone the heparan sulfate D-glucosaminyl 3-O-sulfotransferase (3-OST-1), which is the key enzyme converting nonanticoagulant heparan sulfate (HSinact) to anticoagulant heparan sulfate (HSact).
T4 486-827 Sentence denotes In this study, we expressed and characterized the full-length cDNAs of 3-OST-1 homologous genes, designated as 3-OST-2, 3-OST-3A, and 3-OST-3B as described in the accompanying paper (Shworak, N. W., Liu, J., Petros, L. M., Zhang, L., Kobayashi, M., Copeland, N. G., Jenkins, N. A., and Rosenberg, R. D. (1999) J. Biol. Chem. 274, 5170-5184).
T5 828-968 Sentence denotes All these cDNAs were successfully expressed in COS-7 cells, and heparan sulfate sulfotransferase activities were found in the cell extracts.
T6 969-1219 Sentence denotes We demonstrated that 3-OST-2, 3-OST-3A, and 3-OST-3B are heparan sulfate D-glucosaminyl 3-O-sulfotransferases because the enzymes transfer sulfate from adenosine 3'-phosphophate 5'-phospho-[35S]sulfate ([35S]PAPS) to the 3-OH position of glucosamine.
T7 1220-1276 Sentence denotes 3-OST-3A and 3-OST-3B sulfate an identical disaccharide.
T8 1277-1502 Sentence denotes HSact conversion activity in the cell extract transfected by 3-OST-1 was shown to be 300-fold greater than that in the cell extracts transfected by 3-OST-2 and 3-OST-3A, suggesting that 3-OST-2 and 3-OST-3A do not make HSact.
T9 1503-1699 Sentence denotes The results of the disaccharide analysis of the nitrous acid-degraded [35S]HS suggested that 3-OST-2 transfers sulfate to GlcA2S-GlcNS and IdoA2S-GlcNS; 3-OST-3A transfers sulfate to IdoA2S-GlcNS.
T10 1700-1876 Sentence denotes Our results demonstrate that the 3-O-sulfation of glucosamine is generated by different isoforms depending on the saccharide structures around the modified glucosamine residue.
T11 1877-2030 Sentence denotes This discovery has provided evidence for a new cellular mechanism for generating a defined saccharide sequence in structurally complex HS polysaccharide.

GlyCosmos15-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 14-29 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes heparan sulfate http://www.glycoepitope.jp/epitopes/EP0086
T2 212-227 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes heparan sulfate http://www.glycoepitope.jp/epitopes/EP0086
T3 229-231 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes HS http://www.glycoepitope.jp/epitopes/EP0086
T4 303-318 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes heparan sulfate http://www.glycoepitope.jp/epitopes/EP0086
T5 418-433 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes heparan sulfate http://www.glycoepitope.jp/epitopes/EP0086
T6 461-476 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes heparan sulfate http://www.glycoepitope.jp/epitopes/EP0086
T7 892-907 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes heparan sulfate http://www.glycoepitope.jp/epitopes/EP0086
T8 1026-1041 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes heparan sulfate http://www.glycoepitope.jp/epitopes/EP0086
T9 1578-1580 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes HS http://www.glycoepitope.jp/epitopes/EP0086
T10 2012-2014 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes HS http://www.glycoepitope.jp/epitopes/EP0086