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sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-109 Sentence denotes [Treatment of chronic Wilson's disease in 2 patients using plasmapheresis--clinico-biochemical observations].
TextSentencer_T2 110-214 Sentence denotes Lecenje dva hronicna bolesnika od Vilsonove bolesti pomoću plazmafereze--klinicko-biohemijska zapazanja.
TextSentencer_T3 215-228 Sentence denotes INTRODUCTION:
TextSentencer_T4 229-359 Sentence denotes The introduction of penicillamine in the treatment of Wilson's disease (hepatolenticular degeneration) was a historical event [1].
TextSentencer_T5 360-460 Sentence denotes D-pericillamine (d-PAM) showed some potential side effects such as myasthenia, kidney toxicity, etc.
TextSentencer_T6 461-563 Sentence denotes In previous decade the treatment of Wilson's disease (WD) with zinc sulphate started successfully [4].
TextSentencer_T7 564-724 Sentence denotes Danks [7] described the use of exchanged transfusions, peritoneal dialysis and plasmapheresis in the treatment of young patients with WD in acute liver failure.
TextSentencer_T8 725-767 Sentence denotes These patients had acute copper poisoning.
TextSentencer_T9 768-810 Sentence denotes The results of this study were beneficial.
TextSentencer_T10 811-832 Sentence denotes MATERIAL AND METHODS:
TextSentencer_T11 833-948 Sentence denotes Therapeutic plasmapheresis (PF) has been used in many diseases in which immunological mechanisms are proved [8, 9].
TextSentencer_T12 949-1043 Sentence denotes We started with using PF in the treatment of two young chronic patients with Wilson's disease.
TextSentencer_T13 1044-1151 Sentence denotes The clinical picture of patients became worse, probably due to the decrease in cupriuretic effect of d-PAM.
TextSentencer_T14 1152-1197 Sentence denotes One patient (1) did not take d-PAM regularly.
TextSentencer_T15 1198-1277 Sentence denotes In this study PF was performed with the use of haemonetics V-50 and filter 704.
TextSentencer_T16 1278-1361 Sentence denotes During the treatment with PF, 2000 ml of plasma was always exchanged, i.e. removed.
TextSentencer_T17 1362-1497 Sentence denotes During the treatment with PF the patients were hospitalized at the Department of Neurology and Psychiatry of Children and Young People.
TextSentencer_T18 1498-1522 Sentence denotes CASE REPORT AND RESULTS:
TextSentencer_T19 1523-1534 Sentence denotes Patient No.
TextSentencer_T20 1535-1537 Sentence denotes 1.
TextSentencer_T21 1538-1597 Sentence denotes A 24-year-old man, born in 1965, came with a coarse tremor.
TextSentencer_T22 1598-1643 Sentence denotes He has been diagnosed as WD at the age of 18.
TextSentencer_T23 1644-1717 Sentence denotes Kayser-Fleischer rings were found in the cornea by slit-lamp examination.
TextSentencer_T24 1718-1792 Sentence denotes The disease began when he was 15 years old with polymorphous difficulties.
TextSentencer_T25 1793-1827 Sentence denotes In time tremor became more severe.
TextSentencer_T26 1828-1879 Sentence denotes It was apparent when the patient made any movement.
TextSentencer_T27 1880-1954 Sentence denotes The first treatment with PF (1) lasted from February 13 to March 16, 1989.
TextSentencer_T28 1955-2001 Sentence denotes The patient had 10 PF without any side effect.
TextSentencer_T29 2002-2055 Sentence denotes During the treatment with PF the patient felt better.
TextSentencer_T30 2056-2150 Sentence denotes After PF-tremor was reduced significantly, and subjective and objective condition ameliorated.
TextSentencer_T31 2151-2257 Sentence denotes The patient (1) was readmitted to the hospital on June 24, 1991 for continuation of the treatment with PF.
TextSentencer_T32 2258-2339 Sentence denotes Anamnestic data and neurological examination revealed progression of the disease.
TextSentencer_T33 2340-2386 Sentence denotes His condition became worse, especially tremor.
TextSentencer_T34 2387-2472 Sentence denotes He could not write a single letter (Figures 1-5) and walk without help of the others.
TextSentencer_T35 2473-2548 Sentence denotes His tremor became the severest when he made any kind of voluntary movement.
TextSentencer_T36 2549-2633 Sentence denotes The second treatment with PF started on June 25, 1991 and finished on July 16, 1991.
TextSentencer_T37 2634-2666 Sentence denotes He received 9 PF in this series.
TextSentencer_T38 2667-2706 Sentence denotes The treatment was without side effects.
TextSentencer_T39 2707-2747 Sentence denotes Tremor was reduced approximately by 15%.
TextSentencer_T40 2748-2827 Sentence denotes Plasma copper examined before and after 9 PF showed different values (Table 2).
TextSentencer_T41 2828-2919 Sentence denotes This difference (2.79 mumol/l; 23.70%) in plasma copper level was removed from circulation.
TextSentencer_T42 2920-2931 Sentence denotes Patient No.
TextSentencer_T43 2932-2934 Sentence denotes 2.
TextSentencer_T44 2935-3019 Sentence denotes A 23-year-old man, born in 1966, came to the hospital with acute exacerbation of WD.
TextSentencer_T45 3020-3068 Sentence denotes At the age of 16 latent psychosis was diagnosed.
TextSentencer_T46 3069-3157 Sentence denotes One year later diagnosis of WD was established in the hospital when he was 17 years old.
TextSentencer_T47 3158-3231 Sentence denotes Kayser-Fleischer rings were found in the cornea by slit-lamp examination.
TextSentencer_T48 3232-3415 Sentence denotes The treatment with d-PAM and other drugs (BAL, symptomatic therapies, sedatives, antidepressants, etc.) has been accompanied with good and long-term remissions and short exacerbation.
TextSentencer_T49 3416-3492 Sentence denotes A few years later exacerbation became longer and longer and worse and worse.
TextSentencer_T50 3493-3571 Sentence denotes He was admitted to the hospital on November 28, 1989 with acute relapse of WD.
TextSentencer_T51 3572-3627 Sentence denotes His condition was very difficult, completely bedridden.
TextSentencer_T52 3628-3710 Sentence denotes The treatment with PF started on December 26, 1989 and lasted to January 25, 1990.
TextSentencer_T53 3711-3751 Sentence denotes The treatment with PF was without d-PAM.
TextSentencer_T54 3752-3792 Sentence denotes He was only given symptomatic therapies.
TextSentencer_T55 3793-3945 Sentence denotes After a few PF he demonstrated side effects with nausea, sometimes vomiting, face sweating, pulse rate of about 120/min while blood pressure was normal.
TextSentencer_T56 3946-4034 Sentence denotes Therefore he was given human albumin in the next day, and no side effects were observed.
TextSentencer_T57 4035-4162 Sentence denotes The removal of little plasma copper from blood circulation correlated well with a small improvement in clinical symtpomatology.
TextSentencer_T58 4163-4215 Sentence denotes The rigidity was reduced and voluntary movements bec
T1 0-109 Sentence denotes [Treatment of chronic Wilson's disease in 2 patients using plasmapheresis--clinico-biochemical observations].
T2 110-214 Sentence denotes Lecenje dva hronicna bolesnika od Vilsonove bolesti pomoću plazmafereze--klinicko-biohemijska zapazanja.
T3 215-228 Sentence denotes INTRODUCTION:
T4 229-359 Sentence denotes The introduction of penicillamine in the treatment of Wilson's disease (hepatolenticular degeneration) was a historical event [1].
T5 360-460 Sentence denotes D-pericillamine (d-PAM) showed some potential side effects such as myasthenia, kidney toxicity, etc.
T6 461-563 Sentence denotes In previous decade the treatment of Wilson's disease (WD) with zinc sulphate started successfully [4].
T7 564-724 Sentence denotes Danks [7] described the use of exchanged transfusions, peritoneal dialysis and plasmapheresis in the treatment of young patients with WD in acute liver failure.
T8 725-767 Sentence denotes These patients had acute copper poisoning.
T9 768-810 Sentence denotes The results of this study were beneficial.
T10 811-832 Sentence denotes MATERIAL AND METHODS:
T11 833-948 Sentence denotes Therapeutic plasmapheresis (PF) has been used in many diseases in which immunological mechanisms are proved [8, 9].
T12 949-1043 Sentence denotes We started with using PF in the treatment of two young chronic patients with Wilson's disease.
T13 1044-1151 Sentence denotes The clinical picture of patients became worse, probably due to the decrease in cupriuretic effect of d-PAM.
T14 1152-1197 Sentence denotes One patient (1) did not take d-PAM regularly.
T15 1198-1277 Sentence denotes In this study PF was performed with the use of haemonetics V-50 and filter 704.
T16 1278-1361 Sentence denotes During the treatment with PF, 2000 ml of plasma was always exchanged, i.e. removed.
T17 1362-1497 Sentence denotes During the treatment with PF the patients were hospitalized at the Department of Neurology and Psychiatry of Children and Young People.
T18 1498-1522 Sentence denotes CASE REPORT AND RESULTS:
T19 1523-1534 Sentence denotes Patient No.
T20 1535-1537 Sentence denotes 1.
T21 1538-1597 Sentence denotes A 24-year-old man, born in 1965, came with a coarse tremor.
T22 1598-1643 Sentence denotes He has been diagnosed as WD at the age of 18.
T23 1644-1717 Sentence denotes Kayser-Fleischer rings were found in the cornea by slit-lamp examination.
T24 1718-1792 Sentence denotes The disease began when he was 15 years old with polymorphous difficulties.
T25 1793-1827 Sentence denotes In time tremor became more severe.
T26 1828-1879 Sentence denotes It was apparent when the patient made any movement.
T27 1880-1954 Sentence denotes The first treatment with PF (1) lasted from February 13 to March 16, 1989.
T28 1955-2001 Sentence denotes The patient had 10 PF without any side effect.
T29 2002-2055 Sentence denotes During the treatment with PF the patient felt better.
T30 2056-2150 Sentence denotes After PF-tremor was reduced significantly, and subjective and objective condition ameliorated.
T31 2151-2257 Sentence denotes The patient (1) was readmitted to the hospital on June 24, 1991 for continuation of the treatment with PF.
T32 2258-2339 Sentence denotes Anamnestic data and neurological examination revealed progression of the disease.
T33 2340-2386 Sentence denotes His condition became worse, especially tremor.
T34 2387-2472 Sentence denotes He could not write a single letter (Figures 1-5) and walk without help of the others.
T35 2473-2548 Sentence denotes His tremor became the severest when he made any kind of voluntary movement.
T36 2549-2633 Sentence denotes The second treatment with PF started on June 25, 1991 and finished on July 16, 1991.
T37 2634-2666 Sentence denotes He received 9 PF in this series.
T38 2667-2706 Sentence denotes The treatment was without side effects.
T39 2707-2747 Sentence denotes Tremor was reduced approximately by 15%.
T40 2748-2827 Sentence denotes Plasma copper examined before and after 9 PF showed different values (Table 2).
T41 2828-2919 Sentence denotes This difference (2.79 mumol/l; 23.70%) in plasma copper level was removed from circulation.
T42 2920-2931 Sentence denotes Patient No.
T43 2932-2934 Sentence denotes 2.
T44 2935-3019 Sentence denotes A 23-year-old man, born in 1966, came to the hospital with acute exacerbation of WD.
T45 3020-3068 Sentence denotes At the age of 16 latent psychosis was diagnosed.
T46 3069-3157 Sentence denotes One year later diagnosis of WD was established in the hospital when he was 17 years old.
T47 3158-3231 Sentence denotes Kayser-Fleischer rings were found in the cornea by slit-lamp examination.
T48 3232-3415 Sentence denotes The treatment with d-PAM and other drugs (BAL, symptomatic therapies, sedatives, antidepressants, etc.) has been accompanied with good and long-term remissions and short exacerbation.
T49 3416-3492 Sentence denotes A few years later exacerbation became longer and longer and worse and worse.
T50 3493-3571 Sentence denotes He was admitted to the hospital on November 28, 1989 with acute relapse of WD.
T51 3572-3627 Sentence denotes His condition was very difficult, completely bedridden.
T52 3628-3710 Sentence denotes The treatment with PF started on December 26, 1989 and lasted to January 25, 1990.
T53 3711-3751 Sentence denotes The treatment with PF was without d-PAM.
T54 3752-3792 Sentence denotes He was only given symptomatic therapies.
T55 3793-3945 Sentence denotes After a few PF he demonstrated side effects with nausea, sometimes vomiting, face sweating, pulse rate of about 120/min while blood pressure was normal.
T56 3946-4034 Sentence denotes Therefore he was given human albumin in the next day, and no side effects were observed.
T57 4035-4162 Sentence denotes The removal of little plasma copper from blood circulation correlated well with a small improvement in clinical symtpomatology.
T58 4163-4215 Sentence denotes The rigidity was reduced and voluntary movements bec

PubCasesHPO

Id Subject Object Predicate Lexical cue
AB1 1590-1596 HP:0001337 denotes tremor
AB2 1644-1666 HP:0200032 denotes Kayser-Fleischer rings
AB3 1801-1807 HP:0001337 denotes tremor
AB4 2065-2071 HP:0001337 denotes tremor
AB5 2379-2385 HP:0001337 denotes tremor
AB6 2477-2483 HP:0001337 denotes tremor
AB7 2707-2713 HP:0001337 denotes Tremor
AB8 3044-3053 HP:0000709 denotes psychosis
AB9 3158-3180 HP:0200032 denotes Kayser-Fleischer rings
AB10 3842-3848 HP:0002018 denotes nausea
AB11 3860-3868 HP:0002013 denotes vomiting
AB12 4167-4175 HP:0002063 denotes rigidity

UBERON-AE

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 439-445 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney
PD-UBERON-AE-B_T2 710-715 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
PD-UBERON-AE-B_T3 1685-1691 http://purl.obolibrary.org/obo/UBERON_0000964 denotes cornea
PD-UBERON-AE-B_T4 3199-3205 http://purl.obolibrary.org/obo/UBERON_0000964 denotes cornea
PD-UBERON-AE-B_T5 3860-3868 http://purl.obolibrary.org/obo/UBERON_0000172 denotes vomiting
PD-UBERON-AE-B_T6 3870-3874 http://purl.obolibrary.org/obo/UBERON_0001456 denotes face
PD-UBERON-AE-B_T7 3875-3883 http://purl.obolibrary.org/obo/UBERON_0001089 denotes sweating
PD-UBERON-AE-B_T8 3919-3924 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
PD-UBERON-AE-B_T9 4076-4081 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood

PubCasesORDO

Id Subject Object Predicate Lexical cue
AB1 301-330 ORDO:905 denotes hepatolenticular degeneration
AB2 704-723 ORDO:90062 denotes acute liver failure

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 3860-3868 http://purl.obolibrary.org/obo/UBERON_0000172 denotes vomiting
PD-UBERON-AE-B_T2 710-715 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
PD-UBERON-AE-B_T3 3919-3924 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
PD-UBERON-AE-B_T4 4076-4081 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
PD-UBERON-AE-B_T5 3870-3874 http://purl.obolibrary.org/obo/UBERON_0001456 denotes face
PD-UBERON-AE-B_T6 439-445 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney
PD-UBERON-AE-B_T7 1685-1691 http://purl.obolibrary.org/obo/UBERON_0000964 denotes cornea
PD-UBERON-AE-B_T8 3199-3205 http://purl.obolibrary.org/obo/UBERON_0000964 denotes cornea
PD-UBERON-AE-B_T9 3875-3883 http://purl.obolibrary.org/obo/UBERON_0001089 denotes sweating