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PubMed:9854680
Annnotations
jnlpba-st-training
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 18-41 | protein | denotes | glucocorticoid receptor |
T2 | 87-114 | cell_type | denotes | human mononuclear leukocyte |
T3 | 127-151 | protein | denotes | Glucocorticoid receptors |
T4 | 153-155 | protein | denotes | GR |
T5 | 220-242 | cell_type | denotes | mononuclear leukocytes |
T6 | 244-247 | cell_type | denotes | MNL |
T7 | 447-450 | cell_type | denotes | MNL |
T8 | 1348-1350 | protein | denotes | GR |
T9 | 1555-1557 | protein | denotes | GR |
T10 | 1578-1581 | cell_type | denotes | MNL |
pubmed-sentences-benchmark
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
S1 | 0-126 | Sentence | denotes | The modulation of glucocorticoid receptor content by 3-O-methyl-D-glucose transport in human mononuclear leukocyte in obesity. |
S2 | 127-369 | Sentence | denotes | Glucocorticoid receptors (GR) and 3-O-methyl-D glucose (3-O-MG) transport were determined in mononuclear leukocytes (MNL) from 11 abdominal obese subjects, 10 pituitary-dependent Cushing's syndrome (Cushing's disease) and 10 healthy controls. |
S3 | 370-684 | Sentence | denotes | Using a whole-cell competitive binding assay and 3H-dexamethasone as tracer, MNL of abdominal obese subjects were found to have 4855 +/- 1389 sites/cell which was significantly lower (p < 0.05) than controls (6234 +/- 1568 sites/cell), although no significant difference was found in the mean serum cortisol level. |
S4 | 685-851 | Sentence | denotes | Their mean Kd (affinity) was also significantly lower than that found in the healthy controls (obese Kd:2.92 +/- 0.84 nmol/l, control Kd: 4.55 +/- 0.67 nM, p < 0.05). |
S5 | 852-959 | Sentence | denotes | On the other hand, the receptor characteristics in Cushing's disease patients were within the normal range. |
S6 | 960-1031 | Sentence | denotes | At the same time, 3-O-MG transport was determined in the same subjects. |
S7 | 1032-1281 | Sentence | denotes | In Cushing's disease, 3-O-MG transport was within the normal range, whereas in abdominal obesity this value was significantly lower than the healthy controls (abdominal obese: 31.90 +/- 8.20; control: 46.26 +/- 12.91 fmol/10(6) cell, min, p < 0.05). |
S8 | 1282-1498 | Sentence | denotes | We also found a positive correlation between 3-O-MG transport and GR binding capacity in abdominal subjects (r = 0.89, p < 0.001), however we did not find such a correlation in Cushing's disease (r = 0.60, p > 0.05). |
S9 | 1499-1632 | Sentence | denotes | These results indicated that, in abdominal obesity, the GR binding capacity in MNL is influenced by the changes in glucose transport. |
genia-medco-coref
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
C1 | 161-200 | NP | denotes | 3-O-methyl-D glucose (3-O-MG) transport |
C3 | 254-281 | NP | denotes | 11 abdominal obese subjects |
C4 | 283-368 | NP | denotes | 10 pituitary-dependent Cushing's syndrome (Cushing's disease) and 10 healthy controls |
C2 | 254-368 | NP | denotes | 11 abdominal obese subjects, 10 pituitary-dependent Cushing's syndrome (Cushing's disease) and 10 healthy controls |
C5 | 454-478 | NP | denotes | abdominal obese subjects |
C6 | 498-522 | NP | denotes | 4855 +/- 1389 sites/cell |
C7 | 523-528 | NP | denotes | which |
C8 | 569-577 | NP | denotes | controls |
C9 | 685-690 | NP | denotes | Their |
C10 | 758-778 | NP | denotes | the healthy controls |
C11 | 942-958 | NP | denotes | the normal range |
C12 | 978-994 | NP | denotes | 3-O-MG transport |
C13 | 1013-1030 | NP | denotes | the same subjects |
C14 | 1035-1052 | NP | denotes | Cushing's disease |
C15 | 1054-1070 | NP | denotes | 3-O-MG transport |
C16 | 1082-1098 | NP | denotes | the normal range |
C17 | 1129-1139 | NP | denotes | this value |
C18 | 1169-1189 | NP | denotes | the healthy controls |
C19 | 1327-1343 | NP | denotes | 3-O-MG transport |
C20 | 1371-1389 | NP | denotes | abdominal subjects |
C21 | 1459-1476 | NP | denotes | Cushing's disease |
R1 | C5 | C3 | coref-ident | abdominal obese subjects,11 abdominal obese subjects |
R2 | C7 | C6 | coref-relat | which,4855 +/- 1389 sites/cell |
R3 | C8 | C4 | coref-ident | controls,10 pituitary-dependent Cushing's syndrome (Cushing's disease) and 10 healthy controls |
R4 | C9 | C5 | coref-pron | Their,abdominal obese subjects |
R5 | C12 | C1 | coref-ident | 3-O-MG transport,3-O-methyl-D glucose (3-O-MG) transport |
R6 | C13 | C2 | coref-ident | the same subjects,"11 abdominal obese subjects, 10 pituitary-dependent Cushing's syndrome (Cushing's disease) and 10 healthy controls" |
R7 | C15 | C12 | coref-ident | 3-O-MG transport,3-O-MG transport |
R8 | C16 | C11 | coref-ident | the normal range,the normal range |
R9 | C17 | C15 | coref-ident | this value,3-O-MG transport |
R10 | C18 | C10 | coref-ident | the healthy controls,the healthy controls |
R11 | C19 | C17 | coref-ident | 3-O-MG transport,this value |
R12 | C20 | C5 | coref-ident | abdominal subjects,abdominal obese subjects |
R13 | C21 | C14 | coref-ident | Cushing's disease,Cushing's disease |
GENIAcorpus
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 18-41 | protein_family_or_group | denotes | glucocorticoid receptor |
T2 | 53-73 | carbohydrate | denotes | 3-O-methyl-D-glucose |
T3 | 87-114 | cell_type | denotes | human mononuclear leukocyte |
T4 | 127-151 | protein_family_or_group | denotes | Glucocorticoid receptors |
T5 | 153-155 | protein_family_or_group | denotes | GR |
T6 | 161-181 | carbohydrate | denotes | 3-O-methyl-D glucose |
T7 | 183-189 | carbohydrate | denotes | 3-O-MG |
T8 | 220-242 | cell_type | denotes | mononuclear leukocytes |
T9 | 244-247 | cell_type | denotes | MNL |
T10 | 257-281 | multi_cell | denotes | abdominal obese subjects |
T11 | 286-324 | other_name | denotes | pituitary-dependent Cushing's syndrome |
T12 | 352-368 | multi_cell | denotes | healthy controls |
T13 | 378-414 | other_name | denotes | whole-cell competitive binding assay |
T14 | 419-435 | lipid | denotes | 3H-dexamethasone |
T15 | 447-450 | cell_type | denotes | MNL |
T16 | 454-478 | multi_cell | denotes | abdominal obese subjects |
T17 | 498-522 | cell_component | denotes | 4855 +/- 1389 sites/cell |
T18 | 663-683 | other_name | denotes | serum cortisol level |
T19 | 762-778 | multi_cell | denotes | healthy controls |
T20 | 903-929 | multi_cell | denotes | Cushing's disease patients |
T21 | 978-984 | carbohydrate | denotes | 3-O-MG |
T22 | 1035-1052 | other_name | denotes | Cushing's disease |
T23 | 1054-1060 | carbohydrate | denotes | 3-O-MG |
T24 | 1173-1189 | multi_cell | denotes | healthy controls |
T25 | 1327-1333 | carbohydrate | denotes | 3-O-MG |
T26 | 1348-1350 | protein_family_or_group | denotes | GR |
T27 | 1371-1389 | multi_cell | denotes | abdominal subjects |
T28 | 1459-1476 | other_name | denotes | Cushing's disease |
T29 | 1532-1549 | other_name | denotes | abdominal obesity |
T30 | 1555-1557 | protein_family_or_group | denotes | GR |
T31 | 1578-1581 | cell_type | denotes | MNL |
T32 | 1614-1621 | carbohydrate | denotes | glucose |