PubMed:9540826 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/9540826","sourcedb":"PubMed","sourceid":"9540826","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/9540826","text":"Isolation and expression of a human SRY-related cDNA hSOX20.\nSOX is a family of genes related to the testis-determining gene, SRY. We have isolated and sequenced an hSOX20 cDNA from a cell line of human embryonic carcinoma. This cDNA contains an open reading frame (ORF) encoding 233 amino acids. The protein encompasses an SRY-type HMG box exhibiting strong homologies to those of mouse Sox15 and Sox16. Various adult and fetal tissues were tested for hSOX20 mRNA by Northern analysis. Its expression is restricted to the fetal testis and the size of the transcript is 1.5 knt. Electrophoretic mobility shift assay indicated that recombinant hSOX20 polypeptide is capable of binding to AACAAT sequence.","tracks":[{"project":"bionlp-st-gro-2013-development","denotations":[{"id":"T2","span":{"begin":30,"end":35},"obj":"Eukaryote"},{"id":"T5","span":{"begin":53,"end":59},"obj":"Gene"},{"id":"T6","span":{"begin":61,"end":64},"obj":"Gene"},{"id":"T7","span":{"begin":80,"end":85},"obj":"Gene"},{"id":"T8","span":{"begin":101,"end":124},"obj":"Gene"},{"id":"T9","span":{"begin":126,"end":129},"obj":"Gene"},{"id":"T10","span":{"begin":165,"end":171},"obj":"Gene"},{"id":"T11","span":{"begin":172,"end":176},"obj":"DNA"},{"id":"T12","span":{"begin":184,"end":193},"obj":"Cell"},{"id":"T13","span":{"begin":197,"end":202},"obj":"Eukaryote"},{"id":"T15","span":{"begin":229,"end":233},"obj":"DNA"},{"id":"T16","span":{"begin":246,"end":264},"obj":"OpenReadingFrame"},{"id":"T17","span":{"begin":284,"end":295},"obj":"AminoAcid"},{"id":"T18","span":{"begin":301,"end":308},"obj":"Protein"},{"id":"T19","span":{"begin":324,"end":327},"obj":"Protein"},{"id":"T20","span":{"begin":333,"end":340},"obj":"HMG"},{"id":"T21","span":{"begin":382,"end":387},"obj":"Eukaryote"},{"id":"T22","span":{"begin":388,"end":393},"obj":"Protein"},{"id":"T23","span":{"begin":398,"end":403},"obj":"Protein"},{"id":"T24","span":{"begin":413,"end":436},"obj":"Tissue"},{"id":"T26","span":{"begin":453,"end":459},"obj":"Gene"},{"id":"T27","span":{"begin":460,"end":464},"obj":"MessengerRNA"},{"id":"T29","span":{"begin":523,"end":535},"obj":"Tissue"},{"id":"T30","span":{"begin":556,"end":566},"obj":"Transcript"},{"id":"T31","span":{"begin":643,"end":649},"obj":"Gene"},{"id":"T32","span":{"begin":650,"end":661},"obj":"Peptide"},{"id":"T34","span":{"begin":687,"end":702},"obj":"Sequence"},{"id":"T3","span":{"begin":36,"end":52},"obj":"DNA"},{"id":"E1","span":{"begin":14,"end":24},"obj":"GeneExpression"},{"id":"E2","span":{"begin":203,"end":222},"obj":"Disease"},{"id":"E3","span":{"begin":491,"end":501},"obj":"GeneExpression"},{"id":"E4","span":{"begin":676,"end":683},"obj":"BindingOfProteinToDNA"}],"relations":[{"id":"R4","pred":"locatedIn","subj":"T11","obj":"T12"},{"id":"R5","pred":"fromSpecies","subj":"E2","obj":"T13"},{"id":"R6","pred":"hasPart","subj":"T15","obj":"T16"},{"id":"R7","pred":"encodes","subj":"T16","obj":"T17"},{"id":"R8","pred":"hasPart","subj":"T18","obj":"T20"},{"id":"R9","pred":"fromSpecies","subj":"T22","obj":"T21"},{"id":"R10","pred":"fromSpecies","subj":"T23","obj":"T21"},{"id":"R11","pred":"encodes","subj":"T26","obj":"T27"},{"id":"R14","pred":"locatedIn","subj":"E3","obj":"T29"},{"id":"R15","pred":"encodes","subj":"T31","obj":"T32"},{"id":"R1","pred":"fromSpecies","subj":"T5","obj":"T2"},{"id":"R3","pred":"hasPatient","subj":"T5","obj":"E1"},{"id":"R4","pred":"hasPatient","subj":"T30","obj":"E3"},{"id":"R5","pred":"hasAgent","subj":"T32","obj":"E4"},{"id":"R6","pred":"hasPatient","subj":"T34","obj":"E4"}],"attributes":[{"subj":"T2","pred":"source","obj":"bionlp-st-gro-2013-development"},{"subj":"T5","pred":"source","obj":"bionlp-st-gro-2013-development"},{"subj":"T6","pred":"source","obj":"bionlp-st-gro-2013-development"},{"subj":"T7","pred":"source","obj":"bionlp-st-gro-2013-development"},{"subj":"T8","pred":"source","obj":"bionlp-st-gro-2013-development"},{"subj":"T9","pred":"source","obj":"bionlp-st-gro-2013-development"},{"subj":"T10","pred":"source","obj":"bionlp-st-gro-2013-development"},{"subj":"T11","pred":"source","obj":"bionlp-st-gro-2013-development"},{"subj":"T12","pred":"source","obj":"bionlp-st-gro-2013-development"},{"subj":"T13","pred":"source","obj":"bionlp-st-gro-2013-development"},{"subj":"T15","pred":"source","obj":"bionlp-st-gro-2013-development"},{"subj":"T16","pred":"source","obj":"bionlp-st-gro-2013-development"},{"subj":"T17","pred":"source","obj":"bionlp-st-gro-2013-development"},{"subj":"T18","pred":"source","obj":"bionlp-st-gro-2013-development"},{"subj":"T19","pred":"source","obj":"bionlp-st-gro-2013-development"},{"subj":"T20","pred":"source","obj":"bionlp-st-gro-2013-development"},{"subj":"T21","pred":"source","obj":"bionlp-st-gro-2013-development"},{"subj":"T22","pred":"source","obj":"bionlp-st-gro-2013-development"},{"subj":"T23","pred":"source","obj":"bionlp-st-gro-2013-development"},{"subj":"T24","pred":"source","obj":"bionlp-st-gro-2013-development"},{"subj":"T26","pred":"source","obj":"bionlp-st-gro-2013-development"},{"subj":"T27","pred":"source","obj":"bionlp-st-gro-2013-development"},{"subj":"T29","pred":"source","obj":"bionlp-st-gro-2013-development"},{"subj":"T30","pred":"source","obj":"bionlp-st-gro-2013-development"},{"subj":"T31","pred":"source","obj":"bionlp-st-gro-2013-development"},{"subj":"T32","pred":"source","obj":"bionlp-st-gro-2013-development"},{"subj":"T34","pred":"source","obj":"bionlp-st-gro-2013-development"},{"subj":"T3","pred":"source","obj":"bionlp-st-gro-2013-development"},{"subj":"E1","pred":"source","obj":"bionlp-st-gro-2013-development"},{"subj":"E2","pred":"source","obj":"bionlp-st-gro-2013-development"},{"subj":"E3","pred":"source","obj":"bionlp-st-gro-2013-development"},{"subj":"E4","pred":"source","obj":"bionlp-st-gro-2013-development"}]},{"project":"GlyCosmos15-HP","denotations":[{"id":"T1","span":{"begin":213,"end":222},"obj":"Phenotype"}],"attributes":[{"id":"A1","pred":"hp_id","subj":"T1","obj":"HP:0030731"},{"subj":"T1","pred":"source","obj":"GlyCosmos15-HP"}],"namespaces":[{"prefix":"HP","uri":"http://purl.obolibrary.org/obo/HP_"}]},{"project":"mondo_disease","denotations":[{"id":"T1","span":{"begin":203,"end":222},"obj":"Disease"}],"attributes":[{"id":"A1","pred":"mondo_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/MONDO_0005440"},{"subj":"T1","pred":"source","obj":"mondo_disease"}]},{"project":"NCBITAXON","denotations":[{"id":"T1","span":{"begin":30,"end":35},"obj":"OrganismTaxon"},{"id":"T2","span":{"begin":197,"end":202},"obj":"OrganismTaxon"},{"id":"T3","span":{"begin":382,"end":387},"obj":"OrganismTaxon"}],"attributes":[{"id":"A1","pred":"db_id","subj":"T1","obj":"9606"},{"id":"A2","pred":"db_id","subj":"T2","obj":"9606"},{"id":"A3","pred":"db_id","subj":"T3","obj":"10088"},{"id":"A4","pred":"db_id","subj":"T3","obj":"10090"},{"subj":"T1","pred":"source","obj":"NCBITAXON"},{"subj":"T2","pred":"source","obj":"NCBITAXON"},{"subj":"T3","pred":"source","obj":"NCBITAXON"}]},{"project":"Anatomy-UBERON","denotations":[{"id":"T1","span":{"begin":101,"end":107},"obj":"Body_part"},{"id":"T2","span":{"begin":529,"end":535},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"uberon_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"A2","pred":"uberon_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"subj":"T1","pred":"source","obj":"Anatomy-UBERON"},{"subj":"T2","pred":"source","obj":"Anatomy-UBERON"}]},{"project":"Anatomy-MAT","denotations":[{"id":"T1","span":{"begin":101,"end":107},"obj":"Body_part"},{"id":"T2","span":{"begin":529,"end":535},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"mat_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/MAT_0000132"},{"id":"A2","pred":"mat_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/MAT_0000132"},{"subj":"T1","pred":"source","obj":"Anatomy-MAT"},{"subj":"T2","pred":"source","obj":"Anatomy-MAT"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"bionlp-st-gro-2013-development","color":"#ec9397","default":true},{"id":"GlyCosmos15-HP","color":"#93b1ec"},{"id":"mondo_disease","color":"#cbec93"},{"id":"NCBITAXON","color":"#ec93e5"},{"id":"Anatomy-UBERON","color":"#93ecd8"},{"id":"Anatomy-MAT","color":"#ecbe93"}]}]}}