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PubMed:9406848 JSONTXT

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jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 0-5 protein denotes C/EBP
T2 20-71 DNA denotes human corticotropin-releasing hormone gene promoter
T3 220-262 DNA denotes corticotropin releasing hormone (CRH) gene
T4 302-325 DNA denotes human CRH gene promoter
T5 374-386 DNA denotes CAT reporter
T6 483-503 protein denotes transcription factor
T7 544-573 DNA denotes 3070 bp CRH promoter fragment
T8 604-629 cell_line denotes lymphoblastoid cell lines
T9 670-691 protein denotes transcription factors
T10 692-701 protein denotes C/EBPbeta
T11 703-709 protein denotes NF-IL6
T12 733-743 protein denotes C/EBPdelta
T13 745-755 protein denotes NF-IL6beta
T14 768-771 protein denotes CRH
T15 861-874 protein denotes NF-IL6 mutant
T16 947-952 protein denotes C/EBP
T17 1005-1008 protein denotes CRH
T18 1105-1115 protein denotes NF-IL6beta
T19 1170-1191 protein denotes transcription factors
T20 1208-1216 protein denotes cytokine
T21 1250-1262 DNA denotes CRH promoter

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 0-5 NP denotes C/EBP
C2 16-71 NP denotes the human corticotropin-releasing hormone gene promoter
C3 298-325 NP denotes the human CRH gene promoter
C4 947-952 NP denotes C/EBP
C5 1012-1058 NP denotes the hypothalamus and spleens of arthritic rats
C6 1130-1142 NP denotes these organs
C7 1246-1262 NP denotes the CRH promoter
R1 C3 C2 coref-ident the human CRH gene promoter,the human corticotropin-releasing hormone gene promoter
R2 C4 C1 coref-ident C/EBP,C/EBP
R3 C6 C5 coref-ident these organs,the hypothalamus and spleens of arthritic rats
R4 C7 C3 coref-ident the CRH promoter,the human CRH gene promoter

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-72 Sentence denotes C/EBP activates the human corticotropin-releasing hormone gene promoter.
S2 73-263 Sentence denotes The purpose of these studies was to identify whether transcription factors, associated with cytokine signalling, affected promoter activity of the corticotropin releasing hormone (CRH) gene.
S3 264-387 Sentence denotes Fragments of a 3.6 kb sequence of the human CRH gene promoter were amplified by PCR and ligated upstream of a CAT reporter.
S4 388-523 Sentence denotes These constructs were transfected into a variety of cell lines, either alone or together, with transcription factor expression vectors.
S5 524-630 Sentence denotes Basal activity of a 3070 bp CRH promoter fragment was only seen in neuronal and lymphoblastoid cell lines.
S6 631-757 Sentence denotes Promoter activity was increased by the transcription factors C/EBPbeta (NF-IL6) and more strongly, by C/EBPdelta (NF-IL6beta).
S7 758-953 Sentence denotes Increased CRH promoter activity following phorbol ester treatment was inhibited by a dominant negative NF-IL6 mutant, showing that the effects of phorbol ester were principally mediated by C/EBP.
S8 954-1143 Sentence denotes Moreover, the inverse changes in the expression of CRH in the hypothalamus and spleens of arthritic rats were paralleled by similar inverse changes in NF-IL6beta expression in these organs.
S9 1144-1263 Sentence denotes These data show that some transcription factors associated with cytokine signalling can also activate the CRH promoter.

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 0-5 protein_family_or_group denotes C/EBP
T2 20-71 DNA_domain_or_region denotes human corticotropin-releasing hormone gene promoter
T3 195-212 other_name denotes promoter activity
T4 220-253 DNA_domain_or_region denotes corticotropin releasing hormone (
T5 253-256 protein_molecule denotes CRH
T6 302-307 DNA_domain_or_region denotes human
T7 308-311 protein_molecule denotes CRH
T8 374-386 DNA_family_or_group denotes CAT reporter
T9 483-503 protein_family_or_group denotes transcription factor
T10 544-551 DNA_molecule denotes 3070 bp
T11 552-555 protein_molecule denotes CRH
T12 604-629 cell_line denotes lymphoblastoid cell lines
T13 670-691 protein_family_or_group denotes transcription factors
T14 692-701 protein_molecule denotes C/EBPbeta
T15 703-709 protein_molecule denotes NF-IL6
T16 733-743 protein_molecule denotes C/EBPdelta
T17 745-755 protein_molecule denotes NF-IL6beta
T18 768-771 protein_molecule denotes CRH
T19 772-789 other_name denotes promoter activity
T20 800-813 other_organic_compound denotes phorbol ester
T21 861-874 protein_molecule denotes NF-IL6 mutant
T22 904-917 other_organic_compound denotes phorbol ester
T23 947-952 protein_family_or_group denotes C/EBP
T24 1005-1008 protein_molecule denotes CRH
T25 1105-1115 protein_molecule denotes NF-IL6beta
T26 1170-1191 protein_family_or_group denotes transcription factors
T27 1208-1216 protein_family_or_group denotes cytokine
T28 1250-1253 protein_molecule denotes CRH