PubMed:9390032 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/9390032","sourcedb":"PubMed","sourceid":"9390032","source_url":"https://www.ncbi.nlm.nih.gov/pubmed/9390032","text":"'Revertant' DCIS in human axillary breast carcinoma metastases.\nRecent experimental evidence obtained in Scid mice has suggested that the metastatic process is in large part epigenetically regulated and undergoes partial reversion once the metastatic process is completed: the metastatic colonies become more engaged in the process of growing in situ than actively metastasizing. Based on this experimental evidence, examples were sought of metastatic human cancers where similar reversion to an in situ growth state was occurring. Review of 200 cases of metastatic human breast cancer revealed a 21 per cent incidence of reversion to a ductal carcinoma in situ (DCIS) growth pattern within axillary nodal metastases. The revertant DCIS areas were characterized by an intact and circumferential basement membrane, as demonstrated by extracellular laminin and type IV collagen immunoreactivity. These revertant DCIS areas could be distinguished from primary DCIS, however, by the absence of surrounding myoepithelial cells in the former, identified in the latter by their positive maspin, S-100, and smooth muscle actin immunoreactivity. The pattern of revertant DCIS, poorly differentiated (comedo) (13 per cent), intermediate (non-comedo) (6 per cent), or well-differentiated (non-comedo) (2%), exhibited complete 100 per cent concordance with the primary DCIS pattern. The concordance of histological patterns held true for even the subtypes of DCIS determined by architectural pattern, such as the micropapillary or cribriform subtypes. Nuclear size by digital image analysis and Her-2/neu, p53, and Ki-67 status in the revertant DCIS also exhibited complete concordance with the primary DCIS counterparts. Cases exhibiting a revertant DCIS pattern tended to be ER-negative/EGFR-positive and exhibited significant nodal involvement (mean number, 9; mean area, 90 per cent) compared with cases lacking a revertant pattern (mean number, 4; mean area, 15 per cent) (P \u003c 0.01) These findings suggest that reversion of the metastatic phenotype may also be occurring within autochthonous human metastasis.","tracks":[{"project":"c_corpus","denotations":[{"id":"T2","span":{"begin":12,"end":16},"obj":"CVCL_5552"},{"id":"T1","span":{"begin":12,"end":16},"obj":"D002285"},{"id":"T3","span":{"begin":12,"end":16},"obj":"D002285"},{"id":"T4","span":{"begin":20,"end":25},"obj":"D006801"},{"id":"T5","span":{"begin":35,"end":41},"obj":"UBERON:0000310"},{"id":"T6","span":{"begin":35,"end":51},"obj":"D001943"},{"id":"T7","span":{"begin":35,"end":51},"obj":"D001943"},{"id":"T10","span":{"begin":52,"end":62},"obj":"D009362"},{"id":"T11","span":{"begin":52,"end":62},"obj":"D009362"},{"id":"T12","span":{"begin":105,"end":114},"obj":"D016513"},{"id":"T13","span":{"begin":110,"end":114},"obj":"PR:000005054"},{"id":"T15","span":{"begin":110,"end":114},"obj":"O89094"},{"id":"T17","span":{"begin":189,"end":198},"obj":"SO:0000119"},{"id":"T18","span":{"begin":452,"end":457},"obj":"D006801"},{"id":"T19","span":{"begin":458,"end":465},"obj":"D009369"},{"id":"T20","span":{"begin":458,"end":465},"obj":"D009369"},{"id":"T21","span":{"begin":566,"end":571},"obj":"D006801"},{"id":"T22","span":{"begin":572,"end":578},"obj":"UBERON:0000310"},{"id":"T23","span":{"begin":572,"end":585},"obj":"D001943"},{"id":"T24","span":{"begin":572,"end":585},"obj":"D001943"},{"id":"T28","span":{"begin":637,"end":661},"obj":"D002285"},{"id":"T29","span":{"begin":637,"end":661},"obj":"D002285"},{"id":"T35","span":{"begin":663,"end":667},"obj":"CVCL_5552"},{"id":"T34","span":{"begin":663,"end":667},"obj":"D002285"},{"id":"T36","span":{"begin":663,"end":667},"obj":"D002285"},{"id":"T37","span":{"begin":669,"end":683},"obj":"GO:0007150"},{"id":"T38","span":{"begin":669,"end":683},"obj":"GO:0040007"},{"id":"T39","span":{"begin":700,"end":705},"obj":"PR:000000105"},{"id":"T40","span":{"begin":700,"end":705},"obj":"PR:P43021"},{"id":"T41","span":{"begin":700,"end":705},"obj":"PR:Q96S42"},{"id":"T42","span":{"begin":700,"end":705},"obj":"P43021"},{"id":"T43","span":{"begin":706,"end":716},"obj":"D009362"},{"id":"T44","span":{"begin":706,"end":716},"obj":"D009362"},{"id":"T46","span":{"begin":732,"end":736},"obj":"CVCL_5552"},{"id":"T45","span":{"begin":732,"end":736},"obj":"D002285"},{"id":"T47","span":{"begin":732,"end":736},"obj":"D002285"},{"id":"T48","span":{"begin":795,"end":812},"obj":"GO:0005604"},{"id":"T49","span":{"begin":795,"end":812},"obj":"UBERON:0005769"},{"id":"T53","span":{"begin":833,"end":846},"obj":"GO:0005576"},{"id":"T54","span":{"begin":847,"end":854},"obj":"D007797"},{"id":"T55","span":{"begin":859,"end":875},"obj":"D024141"},{"id":"T57","span":{"begin":867,"end":875},"obj":"2714"},{"id":"T56","span":{"begin":867,"end":875},"obj":"GO:0005202"},{"id":"T61","span":{"begin":910,"end":914},"obj":"CVCL_5552"},{"id":"T60","span":{"begin":910,"end":914},"obj":"D002285"},{"id":"T62","span":{"begin":910,"end":914},"obj":"D002285"},{"id":"T64","span":{"begin":957,"end":961},"obj":"CVCL_5552"},{"id":"T63","span":{"begin":957,"end":961},"obj":"D002285"},{"id":"T65","span":{"begin":957,"end":961},"obj":"D002285"},{"id":"T67","span":{"begin":1080,"end":1086},"obj":"P36952"},{"id":"T68","span":{"begin":1080,"end":1086},"obj":"B1MTB7"},{"id":"T70","span":{"begin":1080,"end":1086},"obj":"P70124"},{"id":"T71","span":{"begin":1080,"end":1086},"obj":"P70564"},{"id":"T72","span":{"begin":1080,"end":1086},"obj":"PR:000014696"},{"id":"T66","span":{"begin":1080,"end":1086},"obj":"C085344"},{"id":"T69","span":{"begin":1080,"end":1086},"obj":"C085344"},{"id":"T73","span":{"begin":1099,"end":1112},"obj":"UBERON:0001135"},{"id":"T74","span":{"begin":1099,"end":1112},"obj":"UBERON:0000953"},{"id":"T77","span":{"begin":1113,"end":1118},"obj":"P53491"},{"id":"T78","span":{"begin":1113,"end":1118},"obj":"P45520"},{"id":"T79","span":{"begin":1113,"end":1118},"obj":"O00937"},{"id":"T80","span":{"begin":1113,"end":1118},"obj":"Q05214"},{"id":"T81","span":{"begin":1113,"end":1118},"obj":"P13363"},{"id":"T82","span":{"begin":1113,"end":1118},"obj":"Q39596"},{"id":"T83","span":{"begin":1113,"end":1118},"obj":"P30161"},{"id":"T84","span":{"begin":1113,"end":1118},"obj":"P53476"},{"id":"T85","span":{"begin":1113,"end":1118},"obj":"P51775"},{"id":"T86","span":{"begin":1113,"end":1118},"obj":"P60011"},{"id":"T87","span":{"begin":1113,"end":1118},"obj":"Q9P4D1"},{"id":"T88","span":{"begin":1113,"end":1118},"obj":"P50138"},{"id":"T89","span":{"begin":1113,"end":1118},"obj":"O65314"},{"id":"T90","span":{"begin":1113,"end":1118},"obj":"P26183"},{"id":"T91","span":{"begin":1113,"end":1118},"obj":"Q75D00"},{"id":"T92","span":{"begin":1113,"end":1118},"obj":"P53502"},{"id":"T93","span":{"begin":1113,"end":1118},"obj":"P11426"},{"id":"T94","span":{"begin":1113,"end":1118},"obj":"P80709"},{"id":"T95","span":{"begin":1113,"end":1118},"obj":"Q8X119"},{"id":"T96","span":{"begin":1113,"end":1118},"obj":"Q6TCF2"},{"id":"T97","span":{"begin":1113,"end":1118},"obj":"Q99023"},{"id":"T98","span":{"begin":1113,"end":1118},"obj":"A5DQP9"},{"id":"T99","span":{"begin":1113,"end":1118},"obj":"P60009"},{"id":"T100","span":{"begin":1113,"end":1118},"obj":"O65315"},{"id":"T101","span":{"begin":1113,"end":1118},"obj":"P26182"},{"id":"T102","span":{"begin":1113,"end":1118},"obj":"Q9UVF3"},{"id":"T103","span":{"begin":1113,"end":1118},"obj":"Q2U7A3"},{"id":"T104","span":{"begin":1113,"end":1118},"obj":"Q92192"},{"id":"T105","span":{"begin":1113,"end":1118},"obj":"Q9UVZ8"},{"id":"T106","span":{"begin":1113,"end":1118},"obj":"P53689"},{"id":"T107","span":{"begin":1113,"end":1118},"obj":"P68555"},{"id":"T108","span":{"begin":1113,"end":1118},"obj":"P53455"},{"id":"T109","span":{"begin":1113,"end":1118},"obj":"O13419"},{"id":"T110","span":{"begin":1113,"end":1118},"obj":"P60010"},{"id":"T111","span":{"begin":1113,"end":1118},"obj":"Q39758"},{"id":"T112","span":{"begin":1113,"end":1118},"obj":"P81085"},{"id":"T113","span":{"begin":1113,"end":1118},"obj":"P48465"},{"id":"T114","span":{"begin":1113,"end":1118},"obj":"P78711"},{"id":"T115","span":{"begin":1113,"end":1118},"obj":"P17128"},{"id":"T116","span":{"begin":1113,"end":1118},"obj":"P91754"},{"id":"T117","span":{"begin":1113,"end":1118},"obj":"Q24733"},{"id":"T118","span":{"begin":1113,"end":1118},"obj":"P14235"},{"id":"T119","span":{"begin":1113,"end":1118},"obj":"Q92193"},{"id":"T120","span":{"begin":1113,"end":1118},"obj":"Q11212"},{"id":"T121","span":{"begin":1113,"end":1118},"obj":"P45521"},{"id":"T122","span":{"begin":1113,"end":1118},"obj":"P53477"},{"id":"T123","span":{"begin":1113,"end":1118},"obj":"P53499"},{"id":"T124","span":{"begin":1113,"end":1118},"obj":"P24902"},{"id":"T125","span":{"begin":1113,"end":1118},"obj":"Q8SWN8"},{"id":"T126","span":{"begin":1113,"end":1118},"obj":"O17320"},{"id":"T127","span":{"begin":1113,"end":1118},"obj":"P10365"},{"id":"T129","span":{"begin":1113,"end":1118},"obj":"O16808"},{"id":"T130","span":{"begin":1113,"end":1118},"obj":"P53498"},{"id":"T131","span":{"begin":1113,"end":1118},"obj":"Q9UVX4"},{"id":"T132","span":{"begin":1113,"end":1118},"obj":"O81221"},{"id":"T133","span":{"begin":1113,"end":1118},"obj":"P20904"},{"id":"T134","span":{"begin":1113,"end":1118},"obj":"O65316"},{"id":"T135","span":{"begin":1113,"end":1118},"obj":"O74258"},{"id":"T136","span":{"begin":1113,"end":1118},"obj":"P53500"},{"id":"T137","span":{"begin":1113,"end":1118},"obj":"P10989"},{"id":"T138","span":{"begin":1113,"end":1118},"obj":"P90689"},{"id":"T128","span":{"begin":1113,"end":1118},"obj":"D000199"},{"id":"T140","span":{"begin":1162,"end":1166},"obj":"CVCL_5552"},{"id":"T139","span":{"begin":1162,"end":1166},"obj":"D002285"},{"id":"T141","span":{"begin":1162,"end":1166},"obj":"D002285"},{"id":"T142","span":{"begin":1214,"end":1226},"obj":"SO:0000933"},{"id":"T144","span":{"begin":1357,"end":1361},"obj":"CVCL_5552"},{"id":"T143","span":{"begin":1357,"end":1361},"obj":"D002285"},{"id":"T145","span":{"begin":1357,"end":1361},"obj":"D002285"},{"id":"T147","span":{"begin":1447,"end":1451},"obj":"CVCL_5552"},{"id":"T146","span":{"begin":1447,"end":1451},"obj":"D002285"},{"id":"T148","span":{"begin":1447,"end":1451},"obj":"D002285"},{"id":"T149","span":{"begin":1583,"end":1588},"obj":"PR:P04626"},{"id":"T150","span":{"begin":1583,"end":1588},"obj":"PR:000002082"},{"id":"T151","span":{"begin":1583,"end":1588},"obj":"PR:Q03557"},{"id":"T152","span":{"begin":1583,"end":1588},"obj":"PR:P34708"},{"id":"T153","span":{"begin":1583,"end":1588},"obj":"PR:Q5AK64"},{"id":"T154","span":{"begin":1589,"end":1592},"obj":"PR:P04626"},{"id":"T155","span":{"begin":1589,"end":1592},"obj":"PR:000002082"},{"id":"T156","span":{"begin":1589,"end":1592},"obj":"PR:000011145"},{"id":"T157","span":{"begin":1589,"end":1592},"obj":"PR:P70424"},{"id":"T159","span":{"begin":1589,"end":1592},"obj":"PR:000011149"},{"id":"T160","span":{"begin":1589,"end":1592},"obj":"PR:O35657"},{"id":"T161","span":{"begin":1589,"end":1592},"obj":"PR:P06494"},{"id":"T162","span":{"begin":1589,"end":1592},"obj":"PR:P29503"},{"id":"T158","span":{"begin":1589,"end":1592},"obj":"CHEBI:23995"},{"id":"T163","span":{"begin":1594,"end":1597},"obj":"PR:P04637"},{"id":"T164","span":{"begin":1594,"end":1597},"obj":"PR:000003035"},{"id":"T165","span":{"begin":1594,"end":1597},"obj":"PR:P02340"},{"id":"T166","span":{"begin":1594,"end":1597},"obj":"PR:Q42578"},{"id":"T167","span":{"begin":1594,"end":1597},"obj":"PR:P10361"},{"id":"T169","span":{"begin":1633,"end":1637},"obj":"CVCL_5552"},{"id":"T168","span":{"begin":1633,"end":1637},"obj":"D002285"},{"id":"T170","span":{"begin":1633,"end":1637},"obj":"D002285"},{"id":"T172","span":{"begin":1691,"end":1695},"obj":"CVCL_5552"},{"id":"T171","span":{"begin":1691,"end":1695},"obj":"D002285"},{"id":"T173","span":{"begin":1691,"end":1695},"obj":"D002285"},{"id":"T175","span":{"begin":1739,"end":1743},"obj":"CVCL_5552"},{"id":"T174","span":{"begin":1739,"end":1743},"obj":"D002285"},{"id":"T176","span":{"begin":1739,"end":1743},"obj":"D002285"},{"id":"T177","span":{"begin":1777,"end":1781},"obj":"PR:Q01279"},{"id":"T178","span":{"begin":1777,"end":1781},"obj":"P0CY46"},{"id":"T179","span":{"begin":1777,"end":1781},"obj":"P04412"},{"id":"T180","span":{"begin":1777,"end":1781},"obj":"PR:P04412"},{"id":"T182","span":{"begin":1777,"end":1781},"obj":"PR:P00533"},{"id":"T183","span":{"begin":1777,"end":1781},"obj":"PR:000006933"},{"id":"T181","span":{"begin":1777,"end":1781},"obj":"GO:0005006"},{"id":"T184","span":{"begin":1817,"end":1822},"obj":"PR:000000105"},{"id":"T185","span":{"begin":1817,"end":1822},"obj":"PR:P43021"},{"id":"T186","span":{"begin":1817,"end":1822},"obj":"PR:Q96S42"},{"id":"T187","span":{"begin":1817,"end":1822},"obj":"P43021"},{"id":"T188","span":{"begin":2085,"end":2090},"obj":"D006801"},{"id":"T189","span":{"begin":2091,"end":2101},"obj":"D009362"},{"id":"T190","span":{"begin":2091,"end":2101},"obj":"D009362"}],"attributes":[{"subj":"T2","pred":"source","obj":"c_corpus"},{"subj":"T1","pred":"source","obj":"c_corpus"},{"subj":"T3","pred":"source","obj":"c_corpus"},{"subj":"T4","pred":"source","obj":"c_corpus"},{"subj":"T5","pred":"source","obj":"c_corpus"},{"subj":"T6","pred":"source","obj":"c_corpus"},{"subj":"T7","pred":"source","obj":"c_corpus"},{"subj":"T10","pred":"source","obj":"c_corpus"},{"subj":"T11","pred":"source","obj":"c_corpus"},{"subj":"T12","pred":"source","obj":"c_corpus"},{"subj":"T13","pred":"source","obj":"c_corpus"},{"subj":"T15","pred":"source","obj":"c_corpus"},{"subj":"T17","pred":"source","obj":"c_corpus"},{"subj":"T18","pred":"source","obj":"c_corpus"},{"subj":"T19","pred":"source","obj":"c_corpus"},{"subj":"T20","pred":"source","obj":"c_corpus"},{"subj":"T21","pred":"source","obj":"c_corpus"},{"subj":"T22","pred":"source","obj":"c_corpus"},{"subj":"T23","pred":"source","obj":"c_corpus"},{"subj":"T24","pred":"source","obj":"c_corpus"},{"subj":"T28","pred":"source","obj":"c_corpus"},{"subj":"T29","pred":"source","obj":"c_corpus"},{"subj":"T35","pred":"source","obj":"c_corpus"},{"subj":"T34","pred":"source","obj":"c_corpus"},{"subj":"T36","pred":"source","obj":"c_corpus"},{"subj":"T37","pred":"source","obj":"c_corpus"},{"subj":"T38","pred":"source","obj":"c_corpus"},{"subj":"T39","pred":"source","obj":"c_corpus"},{"subj":"T40","pred":"source","obj":"c_corpus"},{"subj":"T41","pred":"source","obj":"c_corpus"},{"subj":"T42","pred":"source","obj":"c_corpus"},{"subj":"T43","pred":"source","obj":"c_corpus"},{"subj":"T44","pred":"source","obj":"c_corpus"},{"subj":"T46","pred":"source","obj":"c_corpus"},{"subj":"T45","pred":"source","obj":"c_corpus"},{"subj":"T47","pred":"source","obj":"c_corpus"},{"subj":"T48","pred":"source","obj":"c_corpus"},{"subj":"T49","pred":"source","obj":"c_corpus"},{"subj":"T53","pred":"source","obj":"c_corpus"},{"subj":"T54","pred":"source","obj":"c_corpus"},{"subj":"T55","pred":"source","obj":"c_corpus"},{"subj":"T57","pred":"source","obj":"c_corpus"},{"subj":"T56","pred":"source","obj":"c_corpus"},{"subj":"T61","pred":"source","obj":"c_corpus"},{"subj":"T60","pred":"source","obj":"c_corpus"},{"subj":"T62","pred":"source","obj":"c_corpus"},{"subj":"T64","pred":"source","obj":"c_corpus"},{"subj":"T63","pred":"source","obj":"c_corpus"},{"subj":"T65","pred":"source","obj":"c_corpus"},{"subj":"T67","pred":"source","obj":"c_corpus"},{"subj":"T68","pred":"source","obj":"c_corpus"},{"subj":"T70","pred":"source","obj":"c_corpus"},{"subj":"T71","pred":"source","obj":"c_corpus"},{"subj":"T72","pred":"source","obj":"c_corpus"},{"subj":"T66","pred":"source","obj":"c_corpus"},{"subj":"T69","pred":"source","obj":"c_corpus"},{"subj":"T73","pred":"source","obj":"c_corpus"},{"subj":"T74","pred":"source","obj":"c_corpus"},{"subj":"T77","pred":"source","obj":"c_corpus"},{"subj":"T78","pred":"source","obj":"c_corpus"},{"subj":"T79","pred":"source","obj":"c_corpus"},{"subj":"T80","pred":"source","obj":"c_corpus"},{"subj":"T81","pred":"source","obj":"c_corpus"},{"subj":"T82","pred":"source","obj":"c_corpus"},{"subj":"T83","pred":"source","obj":"c_corpus"},{"subj":"T84","pred":"source","obj":"c_corpus"},{"subj":"T85","pred":"source","obj":"c_corpus"},{"subj":"T86","pred":"source","obj":"c_corpus"},{"subj":"T87","pred":"source","obj":"c_corpus"},{"subj":"T88","pred":"source","obj":"c_corpus"},{"subj":"T89","pred":"source","obj":"c_corpus"},{"subj":"T90","pred":"source","obj":"c_corpus"},{"subj":"T91","pred":"source","obj":"c_corpus"},{"subj":"T92","pred":"source","obj":"c_corpus"},{"subj":"T93","pred":"source","obj":"c_corpus"},{"subj":"T94","pred":"source","obj":"c_corpus"},{"subj":"T95","pred":"source","obj":"c_corpus"},{"subj":"T96","pred":"source","obj":"c_corpus"},{"subj":"T97","pred":"source","obj":"c_corpus"},{"subj":"T98","pred":"source","obj":"c_corpus"},{"subj":"T99","pred":"source","obj":"c_corpus"},{"subj":"T100","pred":"source","obj":"c_corpus"},{"subj":"T101","pred":"source","obj":"c_corpus"},{"subj":"T102","pred":"source","obj":"c_corpus"},{"subj":"T103","pred":"source","obj":"c_corpus"},{"subj":"T104","pred":"source","obj":"c_corpus"},{"subj":"T105","pred":"source","obj":"c_corpus"},{"subj":"T106","pred":"source","obj":"c_corpus"},{"subj":"T107","pred":"source","obj":"c_corpus"},{"subj":"T108","pred":"source","obj":"c_corpus"},{"subj":"T109","pred":"source","obj":"c_corpus"},{"subj":"T110","pred":"source","obj":"c_corpus"},{"subj":"T111","pred":"source","obj":"c_corpus"},{"subj":"T112","pred":"source","obj":"c_corpus"},{"subj":"T113","pred":"source","obj":"c_corpus"},{"subj":"T114","pred":"source","obj":"c_corpus"},{"subj":"T115","pred":"source","obj":"c_corpus"},{"subj":"T116","pred":"source","obj":"c_corpus"},{"subj":"T117","pred":"source","obj":"c_corpus"},{"subj":"T118","pred":"source","obj":"c_corpus"},{"subj":"T119","pred":"source","obj":"c_corpus"},{"subj":"T120","pred":"source","obj":"c_corpus"},{"subj":"T121","pred":"source","obj":"c_corpus"},{"subj":"T122","pred":"source","obj":"c_corpus"},{"subj":"T123","pred":"source","obj":"c_corpus"},{"subj":"T124","pred":"source","obj":"c_corpus"},{"subj":"T125","pred":"source","obj":"c_corpus"},{"subj":"T126","pred":"source","obj":"c_corpus"},{"subj":"T127","pred":"source","obj":"c_corpus"},{"subj":"T129","pred":"source","obj":"c_corpus"},{"subj":"T130","pred":"source","obj":"c_corpus"},{"subj":"T131","pred":"source","obj":"c_corpus"},{"subj":"T132","pred":"source","obj":"c_corpus"},{"subj":"T133","pred":"source","obj":"c_corpus"},{"subj":"T134","pred":"source","obj":"c_corpus"},{"subj":"T135","pred":"source","obj":"c_corpus"},{"subj":"T136","pred":"source","obj":"c_corpus"},{"subj":"T137","pred":"source","obj":"c_corpus"},{"subj":"T138","pred":"source","obj":"c_corpus"},{"subj":"T128","pred":"source","obj":"c_corpus"},{"subj":"T140","pred":"source","obj":"c_corpus"},{"subj":"T139","pred":"source","obj":"c_corpus"},{"subj":"T141","pred":"source","obj":"c_corpus"},{"subj":"T142","pred":"source","obj":"c_corpus"},{"subj":"T144","pred":"source","obj":"c_corpus"},{"subj":"T143","pred":"source","obj":"c_corpus"},{"subj":"T145","pred":"source","obj":"c_corpus"},{"subj":"T147","pred":"source","obj":"c_corpus"},{"subj":"T146","pred":"source","obj":"c_corpus"},{"subj":"T148","pred":"source","obj":"c_corpus"},{"subj":"T149","pred":"source","obj":"c_corpus"},{"subj":"T150","pred":"source","obj":"c_corpus"},{"subj":"T151","pred":"source","obj":"c_corpus"},{"subj":"T152","pred":"source","obj":"c_corpus"},{"subj":"T153","pred":"source","obj":"c_corpus"},{"subj":"T154","pred":"source","obj":"c_corpus"},{"subj":"T155","pred":"source","obj":"c_corpus"},{"subj":"T156","pred":"source","obj":"c_corpus"},{"subj":"T157","pred":"source","obj":"c_corpus"},{"subj":"T159","pred":"source","obj":"c_corpus"},{"subj":"T160","pred":"source","obj":"c_corpus"},{"subj":"T161","pred":"source","obj":"c_corpus"},{"subj":"T162","pred":"source","obj":"c_corpus"},{"subj":"T158","pred":"source","obj":"c_corpus"},{"subj":"T163","pred":"source","obj":"c_corpus"},{"subj":"T164","pred":"source","obj":"c_corpus"},{"subj":"T165","pred":"source","obj":"c_corpus"},{"subj":"T166","pred":"source","obj":"c_corpus"},{"subj":"T167","pred":"source","obj":"c_corpus"},{"subj":"T169","pred":"source","obj":"c_corpus"},{"subj":"T168","pred":"source","obj":"c_corpus"},{"subj":"T170","pred":"source","obj":"c_corpus"},{"subj":"T172","pred":"source","obj":"c_corpus"},{"subj":"T171","pred":"source","obj":"c_corpus"},{"subj":"T173","pred":"source","obj":"c_corpus"},{"subj":"T175","pred":"source","obj":"c_corpus"},{"subj":"T174","pred":"source","obj":"c_corpus"},{"subj":"T176","pred":"source","obj":"c_corpus"},{"subj":"T177","pred":"source","obj":"c_corpus"},{"subj":"T178","pred":"source","obj":"c_corpus"},{"subj":"T179","pred":"source","obj":"c_corpus"},{"subj":"T180","pred":"source","obj":"c_corpus"},{"subj":"T182","pred":"source","obj":"c_corpus"},{"subj":"T183","pred":"source","obj":"c_corpus"},{"subj":"T181","pred":"source","obj":"c_corpus"},{"subj":"T184","pred":"source","obj":"c_corpus"},{"subj":"T185","pred":"source","obj":"c_corpus"},{"subj":"T186","pred":"source","obj":"c_corpus"},{"subj":"T187","pred":"source","obj":"c_corpus"},{"subj":"T188","pred":"source","obj":"c_corpus"},{"subj":"T189","pred":"source","obj":"c_corpus"},{"subj":"T190","pred":"source","obj":"c_corpus"}]},{"project":"UseCases_ArguminSci_Discourse","denotations":[{"id":"T1","span":{"begin":0,"end":63},"obj":"DRI_Background"},{"id":"T2","span":{"begin":64,"end":379},"obj":"DRI_Background"},{"id":"T3","span":{"begin":380,"end":531},"obj":"DRI_Background"},{"id":"T4","span":{"begin":532,"end":717},"obj":"DRI_Background"},{"id":"T5","span":{"begin":718,"end":893},"obj":"DRI_Background"},{"id":"T6","span":{"begin":894,"end":1136},"obj":"DRI_Background"},{"id":"T7","span":{"begin":1137,"end":1370},"obj":"DRI_Outcome"},{"id":"T8","span":{"begin":1371,"end":1539},"obj":"DRI_Challenge"},{"id":"T9","span":{"begin":1540,"end":1709},"obj":"DRI_Background"},{"id":"T10","span":{"begin":1710,"end":2102},"obj":"DRI_Outcome"}],"attributes":[{"subj":"T1","pred":"source","obj":"UseCases_ArguminSci_Discourse"},{"subj":"T2","pred":"source","obj":"UseCases_ArguminSci_Discourse"},{"subj":"T3","pred":"source","obj":"UseCases_ArguminSci_Discourse"},{"subj":"T4","pred":"source","obj":"UseCases_ArguminSci_Discourse"},{"subj":"T5","pred":"source","obj":"UseCases_ArguminSci_Discourse"},{"subj":"T6","pred":"source","obj":"UseCases_ArguminSci_Discourse"},{"subj":"T7","pred":"source","obj":"UseCases_ArguminSci_Discourse"},{"subj":"T8","pred":"source","obj":"UseCases_ArguminSci_Discourse"},{"subj":"T9","pred":"source","obj":"UseCases_ArguminSci_Discourse"},{"subj":"T10","pred":"source","obj":"UseCases_ArguminSci_Discourse"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"c_corpus","color":"#ec93e8","default":true},{"id":"UseCases_ArguminSci_Discourse","color":"#93ecd6"}]}]}}