> top > docs > PubMed:9363920 > annotations

PubMed:9363920 JSONTXT

Annnotations TAB JSON ListView MergeView

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 22-26 protein denotes JAK2
T2 26-32 protein denotes /STAT5
T3 87-106 protein denotes human IL-5 receptor
T4 112-137 protein denotes JAK (Janus kinase) family
T5 141-165 protein denotes protein tyrosine kinases
T6 174-179 protein denotes STATs
T7 181-231 protein denotes signal transducers and activators of transcription
T8 292-301 protein denotes cytokines
T9 306-320 protein denotes growth factors
T10 368-371 protein denotes JAK
T11 371-376 protein denotes /STAT
T12 390-409 protein denotes human interleukin-5
T13 411-416 protein denotes hIL-5
T14 447-474 cell_line denotes hIL-5-responsive cell lines
T15 476-541 cell_line denotes hIL-5 receptor alpha-subunit (hIL-5R alpha) cDNA-transfected TF-1
T16 543-555 cell_line denotes TF-h5R alpha
T17 561-586 cell_line denotes butyric-acid-treated YY-1
T18 588-593 cell_line denotes YY-Bu
T19 600-622 cell_line denotes peripheral eosinophils
T20 730-734 protein denotes JAK2
T21 753-758 protein denotes STAT5
T22 794-799 protein denotes hIL-5
T23 831-836 protein denotes STAT1
T24 869-880 cell_type denotes eosinophils
T25 910-914 protein denotes JAK2
T26 914-920 protein denotes /STAT5
T27 944-947 protein denotes JAK
T28 947-952 protein denotes /STAT
T29 965-970 protein denotes hIL-5

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-107 Sentence denotes The activation of the JAK2/STAT5 pathway is commonly involved in signaling through the human IL-5 receptor.
S2 108-321 Sentence denotes The JAK (Janus kinase) family of protein tyrosine kinases and the STATs (signal transducers and activators of transcription) have been shown to be activated in response to a number of cytokines and growth factors.
S3 322-623 Sentence denotes In this study, we evaluated the activation of JAK/STAT pathway upon human interleukin-5 (hIL-5) stimulation of two different hIL-5-responsive cell lines, hIL-5 receptor alpha-subunit (hIL-5R alpha) cDNA-transfected TF-1 (TF-h5R alpha) and butyric-acid-treated YY-1 (YY-Bu), and peripheral eosinophils.
S4 624-881 Sentence denotes Immunoprecipitation and electrophoretic mobility shift analysis revealed that tyrosine phosphorylation of JAK2 and activation of STAT5 were induced upon stimulation with hIL-5 in all three cell types, while STAT1 activation was only observed in eosinophils.
S5 882-1002 Sentence denotes These results indicate that JAK2/STAT5 activation is a common JAK/STAT pathway for hIL-5-mediated signal in these cells.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 0-40 NP denotes The activation of the JAK2/STAT5 pathway
C3 433-474 NP denotes two different hIL-5-responsive cell lines
C4 476-594 NP denotes hIL-5 receptor alpha-subunit (hIL-5R alpha) cDNA-transfected TF-1 (TF-h5R alpha) and butyric-acid-treated YY-1 (YY-Bu)
C5 600-622 NP denotes peripheral eosinophils
C2 433-622 NP denotes two different hIL-5-responsive cell lines, hIL-5 receptor alpha-subunit (hIL-5R alpha) cDNA-transfected TF-1 (TF-h5R alpha) and butyric-acid-treated YY-1 (YY-Bu), and peripheral eosinophils
C6 803-823 NP denotes all three cell types
C7 869-880 NP denotes eosinophils
C8 910-931 NP denotes JAK2/STAT5 activation
C9 990-1001 NP denotes these cells
R1 C4 C3 coref-appos hIL-5 receptor alpha-subunit (hIL-5R alpha) cDNA-transfected TF-1 (TF-h5R alpha) and butyric-acid-treated YY-1 (YY-Bu),two different hIL-5-responsive cell lines
R2 C6 C2 coref-ident all three cell types,"two different hIL-5-responsive cell lines, hIL-5 receptor alpha-subunit (hIL-5R alpha) cDNA-transfected TF-1 (TF-h5R alpha) and butyric-acid-treated YY-1 (YY-Bu), and peripheral eosinophils"
R3 C7 C5 coref-ident eosinophils,peripheral eosinophils
R4 C8 C1 coref-ident JAK2/STAT5 activation,The activation of the JAK2/STAT5 pathway
R5 C9 C2 coref-ident these cells,"two different hIL-5-responsive cell lines, hIL-5 receptor alpha-subunit (hIL-5R alpha) cDNA-transfected TF-1 (TF-h5R alpha) and butyric-acid-treated YY-1 (YY-Bu), and peripheral eosinophils"

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 22-26 protein_molecule denotes JAK2
T2 26-32 protein_molecule denotes /STAT5
T3 87-106 protein_family_or_group denotes human IL-5 receptor
T4 112-117 protein_family_or_group denotes JAK (
T5 117-129 protein_family_or_group denotes Janus kinase
T6 141-148 protein_family_or_group denotes protein
T7 149-157 amino_acid_monomer denotes tyrosine
T8 174-179 protein_family_or_group denotes STATs
T9 181-231 protein_family_or_group denotes signal transducers and activators of transcription
T10 292-301 protein_family_or_group denotes cytokines
T11 306-320 protein_family_or_group denotes growth factors
T12 368-371 protein_family_or_group denotes JAK
T13 371-376 protein_family_or_group denotes /STAT
T14 390-409 protein_molecule denotes human interleukin-5
T15 411-416 protein_molecule denotes hIL-5
T16 447-452 protein_molecule denotes hIL-5
T17 476-481 protein_molecule denotes hIL-5
T18 506-518 protein_subunit denotes hIL-5R alpha
T19 543-555 cell_line denotes TF-h5R alpha
T20 561-573 other_organic_compound denotes butyric-acid
T21 588-593 cell_line denotes YY-Bu
T22 600-622 cell_line denotes peripheral eosinophils
T23 624-643 other_name denotes Immunoprecipitation
T24 648-687 other_name denotes electrophoretic mobility shift analysis
T25 702-710 amino_acid_monomer denotes tyrosine
T26 730-734 protein_molecule denotes JAK2
T27 753-758 protein_molecule denotes STAT5
T28 794-799 protein_molecule denotes hIL-5
T29 831-836 protein_molecule denotes STAT1
T30 869-880 cell_type denotes eosinophils
T31 910-914 protein_molecule denotes JAK2
T32 914-920 protein_molecule denotes /STAT5
T33 944-947 protein_family_or_group denotes JAK
T34 947-952 protein_family_or_group denotes /STAT
T35 965-970 protein_molecule denotes hIL-5