PubMed:9144218
Annnotations
jnlpba-st-training
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 3-28 | DNA | denotes | enhancer-blocking element |
| T2 | 37-66 | DNA | denotes | alpha and delta gene segments |
| T3 | 78-117 | DNA | denotes | human T cell receptor alpha/delta locus |
| T4 | 119-146 | protein | denotes | T cell receptor (TCR) alpha |
| T5 | 278-303 | DNA | denotes | enhancer-blocking element |
| T6 | 305-311 | DNA | denotes | BEAD-1 |
| T7 | 326-347 | DNA | denotes | element alpha/delta 1 |
| T8 | 368-381 | DNA | denotes | 2.0-kb region |
| T9 | 388-411 | DNA | denotes | TCR delta gene segments |
| T10 | 422-453 | DNA | denotes | TCR alpha joining gene segments |
| T11 | 473-479 | DNA | denotes | BEAD-1 |
| T12 | 507-525 | DNA | denotes | TCR delta enhancer |
| T13 | 527-533 | DNA | denotes | Edelta |
| T14 | 592-622 | DNA | denotes | chromatin-integrated construct |
| T15 | 640-646 | DNA | denotes | BEAD-1 |
| T16 | 690-711 | DNA | denotes | TCR alpha/delta locus |
| T17 | 726-744 | DNA | denotes | regulatory domains |
| T18 | 759-765 | DNA | denotes | Edelta |
| T19 | 774-792 | DNA | denotes | TCR alpha enhancer |
| T20 | 815-821 | DNA | denotes | Edelta |
| T21 | 839-848 | DNA | denotes | chromatin |
| T22 | 856-865 | DNA | denotes | TCR alpha |
genia-medco-coref
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| C3 | 74-117 | NP | denotes | the human T cell receptor alpha/delta locus |
| C2 | 37-117 | NP | denotes | alpha and delta gene segments within the human T cell receptor alpha/delta locus |
| C1 | 0-117 | NP | denotes | An enhancer-blocking element between alpha and delta gene segments within the human T cell receptor alpha/delta locus |
| C4 | 119-170 | NP | denotes | T cell receptor (TCR) alpha and delta gene segments |
| C5 | 192-214 | NP | denotes | a single genetic locus |
| C6 | 275-348 | NP | denotes | An enhancer-blocking element (BEAD-1, for blocking element alpha/delta 1) |
| C7 | 422-453 | NP | denotes | TCR alpha joining gene segments |
| C8 | 461-471 | NP | denotes | this locus |
| C9 | 473-479 | NP | denotes | BEAD-1 |
| C10 | 503-534 | NP | denotes | the TCR delta enhancer (Edelta) |
| C11 | 640-646 | NP | denotes | BEAD-1 |
| C12 | 660-670 | NP | denotes | a boundary |
| C13 | 671-675 | NP | denotes | that |
| C14 | 686-711 | NP | denotes | the TCR alpha/delta locus |
| C15 | 759-765 | NP | denotes | Edelta |
| C16 | 803-805 | NP | denotes | it |
| C17 | 815-821 | NP | denotes | Edelta |
| C18 | 852-887 | NP | denotes | the TCR alpha joining gene segments |
| R1 | C4 | C2 | coref-ident | T cell receptor (TCR) alpha and delta gene segments,alpha and delta gene segments within the human T cell receptor alpha/delta locus |
| R2 | C5 | C3 | coref-ident | a single genetic locus,the human T cell receptor alpha/delta locus |
| R3 | C6 | C1 | coref-ident | "An enhancer-blocking element (BEAD-1, for blocking element alpha/delta 1)",An enhancer-blocking element between alpha and delta gene segments within the human T cell receptor alpha/delta locus |
| R4 | C8 | C5 | coref-ident | this locus,a single genetic locus |
| R5 | C9 | C6 | coref-ident | BEAD-1,"An enhancer-blocking element (BEAD-1, for blocking element alpha/delta 1)" |
| R6 | C11 | C9 | coref-ident | BEAD-1,BEAD-1 |
| R7 | C13 | C12 | coref-relat | that,a boundary |
| R8 | C14 | C8 | coref-ident | the TCR alpha/delta locus,this locus |
| R9 | C15 | C10 | coref-ident | Edelta,the TCR delta enhancer (Edelta) |
| R10 | C16 | C11 | coref-pron | it,BEAD-1 |
| R11 | C17 | C15 | coref-ident | Edelta,Edelta |
| R12 | C18 | C7 | coref-ident | the TCR alpha joining gene segments,TCR alpha joining gene segments |
pubmed-sentences-benchmark
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| S1 | 0-118 | Sentence | denotes | An enhancer-blocking element between alpha and delta gene segments within the human T cell receptor alpha/delta locus. |
| S2 | 119-274 | Sentence | denotes | T cell receptor (TCR) alpha and delta gene segments are organized within a single genetic locus but are differentially regulated during T cell development. |
| S3 | 275-472 | Sentence | denotes | An enhancer-blocking element (BEAD-1, for blocking element alpha/delta 1) was localized to a 2.0-kb region 3' of TCR delta gene segments and 5' of TCR alpha joining gene segments within this locus. |
| S4 | 473-623 | Sentence | denotes | BEAD-1 blocked the ability of the TCR delta enhancer (Edelta) to activate a promoter when located between the two in a chromatin-integrated construct. |
| S5 | 624-950 | Sentence | denotes | We propose that BEAD-1 functions as a boundary that separates the TCR alpha/delta locus into distinct regulatory domains controlled by Edelta and the TCR alpha enhancer, and that it prevents Edelta from opening the chromatin of the TCR alpha joining gene segments for VDJ recombination at an early stage of T cell development. |
GENIAcorpus
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 3-28 | DNA_domain_or_region | denotes | enhancer-blocking element |
| T2 | 78-117 | DNA_domain_or_region | denotes | human T cell receptor alpha/delta locus |
| T3 | 119-146 | protein_molecule | denotes | T cell receptor (TCR) alpha |
| T4 | 255-273 | other_name | denotes | T cell development |
| T5 | 278-303 | DNA_domain_or_region | denotes | enhancer-blocking element |
| T6 | 305-311 | DNA_domain_or_region | denotes | BEAD-1 |
| T7 | 326-347 | DNA_domain_or_region | denotes | element alpha/delta 1 |
| T8 | 368-381 | DNA_domain_or_region | denotes | 2.0-kb region |
| T9 | 388-411 | DNA_domain_or_region | denotes | TCR delta gene segments |
| T10 | 422-453 | DNA_domain_or_region | denotes | TCR alpha joining gene segments |
| T11 | 473-479 | DNA_domain_or_region | denotes | BEAD-1 |
| T12 | 507-525 | DNA_domain_or_region | denotes | TCR delta enhancer |
| T13 | 527-533 | DNA_domain_or_region | denotes | Edelta |
| T14 | 592-622 | DNA_family_or_group | denotes | chromatin-integrated construct |
| T15 | 640-646 | DNA_domain_or_region | denotes | BEAD-1 |
| T16 | 690-711 | DNA_domain_or_region | denotes | TCR alpha/delta locus |
| T17 | 726-744 | DNA_domain_or_region | denotes | regulatory domains |
| T18 | 759-765 | DNA_domain_or_region | denotes | Edelta |
| T19 | 774-792 | DNA_domain_or_region | denotes | TCR alpha enhancer |
| T20 | 815-821 | DNA_domain_or_region | denotes | Edelta |
| T21 | 839-848 | DNA_family_or_group | denotes | chromatin |
| T22 | 856-865 | DNA_domain_or_region | denotes | TCR alpha |
| T23 | 892-909 | other_name | denotes | VDJ recombination |
| T24 | 931-949 | other_name | denotes | T cell development |