> top > docs > PubMed:8724135 > annotations

PubMed:8724135 JSONTXT

Annnotations TAB JSON ListView MergeView

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-136 Sentence denotes Transcription of the beta-galactoside alpha 2,6-sialyltransferase gene in B lymphocytes is directed by a separate and distinct promoter.
TextSentencer_T2 137-270 Sentence denotes A single human gene, SIAT1, encodes the beta-galactoside alpha 2,6-sialyltransferase from which multiple mRNA isoforms are generated.
TextSentencer_T3 271-416 Sentence denotes In rat, expression of the hepatic mRNA isoform (Form 1) has been defined with respect to the transcriptional initiation site and promoter region.
TextSentencer_T4 417-488 Sentence denotes We show here that a similar hepatic SIAT1 mRNA isoform exists in human.
TextSentencer_T5 489-589 Sentence denotes Another human mRNA isoform, a mature B-cell-specific mRNA isoform (Form 2), was previously reported.
TextSentencer_T6 590-712 Sentence denotes Here, we used 5'-RACE and S1 nuclease protection analysis to define the 5'-untranslated region of Form 2 human SIAT1 mRNA.
TextSentencer_T7 713-829 Sentence denotes We demonstrate conclusively that Form 2 mRNA is initiated from a point completely distinct from that of Form 1 mRNA.
TextSentencer_T8 830-983 Sentence denotes A number of cis-acting regulatory elements residing immediately 5'of the Form 2 initiation site includes AP-1, AP-2, NF-kappa B, NF-IL6, C/EBP, and CREB.
TextSentencer_T9 984-1060 Sentence denotes A TATAA box is also present 29 bp 5' of the transcriptional initiation site.
TextSentencer_T10 1061-1313 Sentence denotes CAT reporter gene expression from serially-truncated segments of the 5'-flanking region of the Form 2 initiation site indicates that the segment between -784 and +125 was sufficient to promote high level CAT expression in Louckes, a mature B-cell line.
TextSentencer_T11 1314-1488 Sentence denotes The 5'-flanking region to the human Form 1 initiation site is competent in expression of CAT upon transfection of the fusion construct into HepG2, a human hepatoma cell line.
TextSentencer_T12 1489-1547 Sentence denotes Cellular specificity of expression is apparently retained.
TextSentencer_T13 1548-1654 Sentence denotes Louckes cells expressed CAT efficiently from Form 2 promoter but only marginally from the Form 1 promoter.
TextSentencer_T14 1655-1767 Sentence denotes In contrast, CAT expression from Form 1 promoter is more efficient than from the Form 2 promoter in HepG2 cells.
T1 0-136 Sentence denotes Transcription of the beta-galactoside alpha 2,6-sialyltransferase gene in B lymphocytes is directed by a separate and distinct promoter.
T2 137-270 Sentence denotes A single human gene, SIAT1, encodes the beta-galactoside alpha 2,6-sialyltransferase from which multiple mRNA isoforms are generated.
T3 271-416 Sentence denotes In rat, expression of the hepatic mRNA isoform (Form 1) has been defined with respect to the transcriptional initiation site and promoter region.
T4 417-488 Sentence denotes We show here that a similar hepatic SIAT1 mRNA isoform exists in human.
T5 489-589 Sentence denotes Another human mRNA isoform, a mature B-cell-specific mRNA isoform (Form 2), was previously reported.
T6 590-712 Sentence denotes Here, we used 5'-RACE and S1 nuclease protection analysis to define the 5'-untranslated region of Form 2 human SIAT1 mRNA.
T7 713-829 Sentence denotes We demonstrate conclusively that Form 2 mRNA is initiated from a point completely distinct from that of Form 1 mRNA.
T8 830-983 Sentence denotes A number of cis-acting regulatory elements residing immediately 5'of the Form 2 initiation site includes AP-1, AP-2, NF-kappa B, NF-IL6, C/EBP, and CREB.
T9 984-1060 Sentence denotes A TATAA box is also present 29 bp 5' of the transcriptional initiation site.
T10 1061-1313 Sentence denotes CAT reporter gene expression from serially-truncated segments of the 5'-flanking region of the Form 2 initiation site indicates that the segment between -784 and +125 was sufficient to promote high level CAT expression in Louckes, a mature B-cell line.
T11 1314-1488 Sentence denotes The 5'-flanking region to the human Form 1 initiation site is competent in expression of CAT upon transfection of the fusion construct into HepG2, a human hepatoma cell line.
T12 1489-1547 Sentence denotes Cellular specificity of expression is apparently retained.
T13 1548-1654 Sentence denotes Louckes cells expressed CAT efficiently from Form 2 promoter but only marginally from the Form 1 promoter.
T14 1655-1767 Sentence denotes In contrast, CAT expression from Form 1 promoter is more efficient than from the Form 2 promoter in HepG2 cells.
T1 0-136 Sentence denotes Transcription of the beta-galactoside alpha 2,6-sialyltransferase gene in B lymphocytes is directed by a separate and distinct promoter.
T2 137-270 Sentence denotes A single human gene, SIAT1, encodes the beta-galactoside alpha 2,6-sialyltransferase from which multiple mRNA isoforms are generated.
T3 271-416 Sentence denotes In rat, expression of the hepatic mRNA isoform (Form 1) has been defined with respect to the transcriptional initiation site and promoter region.
T4 417-488 Sentence denotes We show here that a similar hepatic SIAT1 mRNA isoform exists in human.
T5 489-589 Sentence denotes Another human mRNA isoform, a mature B-cell-specific mRNA isoform (Form 2), was previously reported.
T6 590-712 Sentence denotes Here, we used 5'-RACE and S1 nuclease protection analysis to define the 5'-untranslated region of Form 2 human SIAT1 mRNA.
T7 713-829 Sentence denotes We demonstrate conclusively that Form 2 mRNA is initiated from a point completely distinct from that of Form 1 mRNA.
T8 830-983 Sentence denotes A number of cis-acting regulatory elements residing immediately 5'of the Form 2 initiation site includes AP-1, AP-2, NF-kappa B, NF-IL6, C/EBP, and CREB.
T9 984-1060 Sentence denotes A TATAA box is also present 29 bp 5' of the transcriptional initiation site.
T10 1061-1313 Sentence denotes CAT reporter gene expression from serially-truncated segments of the 5'-flanking region of the Form 2 initiation site indicates that the segment between -784 and +125 was sufficient to promote high level CAT expression in Louckes, a mature B-cell line.
T11 1314-1488 Sentence denotes The 5'-flanking region to the human Form 1 initiation site is competent in expression of CAT upon transfection of the fusion construct into HepG2, a human hepatoma cell line.
T12 1489-1547 Sentence denotes Cellular specificity of expression is apparently retained.
T13 1548-1654 Sentence denotes Louckes cells expressed CAT efficiently from Form 2 promoter but only marginally from the Form 1 promoter.
T14 1655-1767 Sentence denotes In contrast, CAT expression from Form 1 promoter is more efficient than from the Form 2 promoter in HepG2 cells.

DisGeNET

Id Subject Object Predicate Lexical cue
T0 1403-1406 gene:847 denotes CAT
T1 1469-1477 disease:C0023903 denotes hepatoma
T2 1403-1406 gene:847 denotes CAT
T3 1469-1477 disease:C2239176 denotes hepatoma
T4 1403-1406 gene:1384 denotes CAT
T5 1469-1477 disease:C0023903 denotes hepatoma
T6 1403-1406 gene:1384 denotes CAT
T7 1469-1477 disease:C2239176 denotes hepatoma
T8 1403-1406 gene:10249 denotes CAT
T9 1469-1477 disease:C0023903 denotes hepatoma
T10 1403-1406 gene:10249 denotes CAT
T11 1469-1477 disease:C2239176 denotes hepatoma
R1 T0 T1 associated_with CAT,hepatoma
R2 T2 T3 associated_with CAT,hepatoma
R3 T4 T5 associated_with CAT,hepatoma
R4 T6 T7 associated_with CAT,hepatoma
R5 T8 T9 associated_with CAT,hepatoma
R6 T10 T11 associated_with CAT,hepatoma

GlycoBiology-FMA

Id Subject Object Predicate Lexical cue
_T1 66-70 FMAID:198663 denotes gene
_T2 74-87 FMAID:167173 denotes B lymphocytes
_T3 74-87 FMAID:62869 denotes B lymphocytes
_T4 74-87 FMAID:167174 denotes B lymphocytes
_T5 74-87 FMAID:167176 denotes B lymphocytes
_T6 74-87 FMAID:167171 denotes B lymphocytes
_T7 74-87 FMAID:62870 denotes B lymphocytes
_T8 76-87 FMAID:167163 denotes lymphocytes
_T9 76-87 FMAID:62863 denotes lymphocytes
_T10 152-156 FMAID:198663 denotes gene
_T11 616-618 FMAID:63522 denotes S1
_T12 616-618 FMAID:167750 denotes S1
_T13 778-783 FMAID:146304 denotes point
_T14 778-783 FMAID:50596 denotes point
_T15 1074-1078 FMAID:198663 denotes gene
_T16 1114-1122 FMAID:256626 denotes segments
_T17 1114-1122 FMAID:11367 denotes segments
_T18 1114-1122 FMAID:99729 denotes segments
_T19 1114-1122 FMAID:256624 denotes segments
_T20 1114-1122 FMAID:256625 denotes segments
_T21 1114-1122 FMAID:256632 denotes segments
_T22 1114-1122 FMAID:256633 denotes segments
_T23 1114-1122 FMAID:256627 denotes segments
_T24 1114-1122 FMAID:256630 denotes segments
_T25 1114-1122 FMAID:256631 denotes segments
_T26 1114-1122 FMAID:256628 denotes segments
_T27 1114-1122 FMAID:256629 denotes segments
_T28 1114-1129 FMAID:258811 denotes segments of the
_T29 1114-1129 FMAID:74845 denotes segments of the
_T30 1133-1141 FMAID:104341 denotes flanking
_T31 1198-1205 FMAID:256633 denotes segment
_T32 1198-1205 FMAID:256627 denotes segment
_T33 1198-1205 FMAID:256630 denotes segment
_T34 1198-1205 FMAID:256631 denotes segment
_T35 1198-1205 FMAID:256625 denotes segment
_T36 1198-1205 FMAID:256624 denotes segment
_T37 1198-1205 FMAID:256632 denotes segment
_T38 1198-1205 FMAID:256626 denotes segment
_T39 1198-1205 FMAID:256629 denotes segment
_T40 1198-1205 FMAID:256628 denotes segment
_T41 1198-1205 FMAID:99729 denotes segment
_T42 1198-1205 FMAID:11367 denotes segment
_T43 1321-1329 FMAID:104341 denotes flanking
_T44 1556-1561 FMAID:68646 denotes cells
_T45 1556-1561 FMAID:169002 denotes cells
_T46 1761-1766 FMAID:68646 denotes cells
_T47 1761-1766 FMAID:169002 denotes cells

uniprot-human

Id Subject Object Predicate Lexical cue
T1 158-163 http://www.uniprot.org/uniprot/P15907 denotes SIAT1
T2 453-458 http://www.uniprot.org/uniprot/P15907 denotes SIAT1
T3 701-706 http://www.uniprot.org/uniprot/P15907 denotes SIAT1
T4 941-945 http://www.uniprot.org/uniprot/P05549 denotes AP-2
T5 962-965 http://www.uniprot.org/uniprot/P05231 denotes IL6
T6 969-972 http://www.uniprot.org/uniprot/Q15125 denotes EBP
T7 969-972 http://www.uniprot.org/uniprot/Q5HYK7 denotes EBP
T8 1061-1064 http://www.uniprot.org/uniprot/P04040 denotes CAT
T9 1265-1268 http://www.uniprot.org/uniprot/P04040 denotes CAT
T10 1403-1406 http://www.uniprot.org/uniprot/P04040 denotes CAT
T11 1572-1575 http://www.uniprot.org/uniprot/P04040 denotes CAT
T12 1668-1671 http://www.uniprot.org/uniprot/P04040 denotes CAT
T13 1061-1064 http://www.uniprot.org/uniprot/Q6IB77 denotes CAT
T14 1265-1268 http://www.uniprot.org/uniprot/Q6IB77 denotes CAT
T15 1403-1406 http://www.uniprot.org/uniprot/Q6IB77 denotes CAT
T16 1572-1575 http://www.uniprot.org/uniprot/Q6IB77 denotes CAT
T17 1668-1671 http://www.uniprot.org/uniprot/Q6IB77 denotes CAT
T18 1061-1064 http://www.uniprot.org/uniprot/P43155 denotes CAT
T19 1265-1268 http://www.uniprot.org/uniprot/P43155 denotes CAT
T20 1403-1406 http://www.uniprot.org/uniprot/P43155 denotes CAT
T21 1572-1575 http://www.uniprot.org/uniprot/P43155 denotes CAT
T22 1668-1671 http://www.uniprot.org/uniprot/P43155 denotes CAT

uniprot-mouse

Id Subject Object Predicate Lexical cue
T1 842-845 http://www.uniprot.org/uniprot/Q62225 denotes cis
T2 935-939 http://www.uniprot.org/uniprot/P05627 denotes AP-1
T3 941-945 http://www.uniprot.org/uniprot/Q91VX0 denotes AP-2
T4 1061-1064 http://www.uniprot.org/uniprot/P47934 denotes CAT
T5 1265-1268 http://www.uniprot.org/uniprot/P47934 denotes CAT
T6 1403-1406 http://www.uniprot.org/uniprot/P47934 denotes CAT
T7 1572-1575 http://www.uniprot.org/uniprot/P47934 denotes CAT
T8 1668-1671 http://www.uniprot.org/uniprot/P47934 denotes CAT

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 21-25 http://purl.bioontology.org/ontology/NCBITAXON/3554 denotes beta
T2 21-25 http://purl.bioontology.org/ontology/NCBITAXON/158455 denotes beta
T3 177-181 http://purl.bioontology.org/ontology/NCBITAXON/3554 denotes beta
T4 177-181 http://purl.bioontology.org/ontology/NCBITAXON/158455 denotes beta
T5 842-845 http://purl.bioontology.org/ontology/NCBITAXON/245896 denotes cis
T6 1556-1561 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T7 1761-1766 http://purl.bioontology.org/ontology/STY/T025 denotes cells

GO-BP

Id Subject Object Predicate Lexical cue
T1 0-13 http://purl.obolibrary.org/obo/GO_0006351 denotes Transcription
T2 364-379 http://purl.obolibrary.org/obo/GO_0006351 denotes transcriptional
T3 1028-1043 http://purl.obolibrary.org/obo/GO_0006351 denotes transcriptional
T4 1061-1064 http://purl.obolibrary.org/obo/GO_0004096 denotes CAT
T5 1265-1268 http://purl.obolibrary.org/obo/GO_0004096 denotes CAT
T6 1403-1406 http://purl.obolibrary.org/obo/GO_0004096 denotes CAT
T7 1572-1575 http://purl.obolibrary.org/obo/GO_0004096 denotes CAT
T8 1668-1671 http://purl.obolibrary.org/obo/GO_0004096 denotes CAT
T9 1074-1089 http://purl.obolibrary.org/obo/GO_0010467 denotes gene expression
T10 1114-1122 http://purl.obolibrary.org/obo/GO_0035282 denotes segments
T11 1198-1205 http://purl.obolibrary.org/obo/GO_0035282 denotes segment
T12 1489-1497 http://purl.obolibrary.org/obo/GO_0007349 denotes Cellular

GO-CC

Id Subject Object Predicate Lexical cue
T1 528-532 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T2 1303-1307 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T3 1478-1482 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T4 1556-1561 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T5 1761-1766 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

EDAM-topics

Id Subject Object Predicate Lexical cue
T1 0-13 http://edamontology.org/topic_0110 denotes Transcription
T2 0-13 http://edamontology.org/topic_3308 denotes Transcription
T3 0-13 http://edamontology.org/topic_0203 denotes Transcription
T4 0-13 http://edamontology.org/topic_3512 denotes Transcription
T5 127-135 http://edamontology.org/topic_0749 denotes promoter
T6 127-135 http://edamontology.org/topic_1312 denotes promoter
T7 127-135 http://edamontology.org/topic_0111 denotes promoter
T8 146-151 http://edamontology.org/topic_2815 denotes human
T9 146-156 http://edamontology.org/topic_3574 denotes human gene
T10 364-379 http://edamontology.org/topic_3308 denotes transcriptional
T11 364-379 http://edamontology.org/topic_0110 denotes transcriptional
T12 364-379 http://edamontology.org/topic_3512 denotes transcriptional
T13 364-379 http://edamontology.org/topic_0203 denotes transcriptional
T14 400-408 http://edamontology.org/topic_0111 denotes promoter
T15 400-408 http://edamontology.org/topic_1312 denotes promoter
T16 400-408 http://edamontology.org/topic_0749 denotes promoter
T17 482-487 http://edamontology.org/topic_2815 denotes human
T18 497-502 http://edamontology.org/topic_2815 denotes human
T19 695-700 http://edamontology.org/topic_2815 denotes human
T20 1028-1043 http://edamontology.org/topic_3512 denotes transcriptional
T21 1028-1043 http://edamontology.org/topic_3308 denotes transcriptional
T22 1028-1043 http://edamontology.org/topic_0110 denotes transcriptional
T23 1028-1043 http://edamontology.org/topic_0203 denotes transcriptional
T24 1074-1089 http://edamontology.org/topic_0203 denotes gene expression
T25 1246-1253 http://edamontology.org/topic_1312 denotes promote
T26 1246-1253 http://edamontology.org/topic_0749 denotes promote
T27 1246-1253 http://edamontology.org/topic_0111 denotes promote
T28 1344-1349 http://edamontology.org/topic_2815 denotes human
T29 1463-1468 http://edamontology.org/topic_2815 denotes human
T30 1600-1608 http://edamontology.org/topic_0111 denotes promoter
T31 1600-1608 http://edamontology.org/topic_1312 denotes promoter
T32 1600-1608 http://edamontology.org/topic_0749 denotes promoter
T33 1645-1653 http://edamontology.org/topic_0749 denotes promoter
T34 1645-1653 http://edamontology.org/topic_0111 denotes promoter
T35 1645-1653 http://edamontology.org/topic_1312 denotes promoter
T36 1695-1703 http://edamontology.org/topic_0749 denotes promoter
T37 1695-1703 http://edamontology.org/topic_0111 denotes promoter
T38 1695-1703 http://edamontology.org/topic_1312 denotes promoter
T39 1743-1751 http://edamontology.org/topic_0749 denotes promoter
T40 1743-1751 http://edamontology.org/topic_0111 denotes promoter
T41 1743-1751 http://edamontology.org/topic_1312 denotes promoter

EDAM-DFO

Id Subject Object Predicate Lexical cue
T1 260-269 http://edamontology.org/operation_3429 denotes generated
T2 580-588 http://edamontology.org/data_2048 denotes reported
T3 628-647 http://edamontology.org/operation_2502 denotes protection analysis
T4 639-647 http://edamontology.org/operation_2945 denotes analysis
T5 716-727 http://edamontology.org/operation_2246 denotes demonstrate
T6 853-872 http://edamontology.org/operation_0438 denotes regulatory elements
T7 873-881 http://edamontology.org/data_2619 denotes residing
T8 1065-1073 http://edamontology.org/data_2048 denotes reporter
T9 1439-1448 http://edamontology.org/operation_3429 denotes construct

GlycoBiology-Epitope

Id Subject Object Predicate Lexical cue
PD-GlycoEpitope-B_T1 616-618 http://www.glycoepitope.jp/epitopes/AN0638 denotes S1

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 1469-1477 Disease denotes hepatoma http://purl.obolibrary.org/obo/MONDO_0007256

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 146-151 OrganismTaxon denotes human 9606
T2 274-277 OrganismTaxon denotes rat 10114|10116
T4 482-487 OrganismTaxon denotes human 9606
T5 497-502 OrganismTaxon denotes human 9606
T6 695-700 OrganismTaxon denotes human 9606
T7 1344-1349 OrganismTaxon denotes human 9606
T8 1463-1468 OrganismTaxon denotes human 9606

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 74-87 Body_part denotes B lymphocytes http://purl.obolibrary.org/obo/CL_0000236
T2 519-532 Body_part denotes mature B-cell http://purl.obolibrary.org/obo/CL_0000785
T3 1114-1122 Body_part denotes segments http://purl.obolibrary.org/obo/UBERON_0000914
T4 1198-1205 Body_part denotes segment http://purl.obolibrary.org/obo/UBERON_0000914
T5 1294-1307 Body_part denotes mature B-cell http://purl.obolibrary.org/obo/CL_0000785

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 74-87 Cell denotes B lymphocytes http://purl.obolibrary.org/obo/CL:0000236
T2 519-532 Cell denotes mature B-cell http://purl.obolibrary.org/obo/CL:0000785
T3 526-532 Cell denotes B-cell http://purl.obolibrary.org/obo/CL:0000236
T4 1294-1307 Cell denotes mature B-cell http://purl.obolibrary.org/obo/CL:0000785
T5 1301-1307 Cell denotes B-cell http://purl.obolibrary.org/obo/CL:0000236