PubMed:8631981
Annnotations
ggdb-test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 715-718 | https://acgg.asia/db/ggdb/info/gg052 | denotes | GM3 |
GlyCosmos6-Glycan-Motif-Image
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 30-33 | Glycan_Motif | denotes | GT3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G93899SO|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G33570YF |
| T3 | 44-47 | Glycan_Motif | denotes | GD3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G98544DH|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81928IQ |
| T5 | 52-55 | Glycan_Motif | denotes | GT3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G93899SO|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G33570YF |
| T7 | 129-132 | Glycan_Motif | denotes | GT3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G93899SO|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G33570YF |
| T9 | 284-287 | Glycan_Motif | denotes | GT3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G93899SO|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G33570YF |
| T11 | 328-339 | Glycan_Motif | denotes | sialic acid | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY |
| T12 | 343-346 | Glycan_Motif | denotes | GD3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G98544DH|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81928IQ |
| T14 | 416-419 | Glycan_Motif | denotes | GT3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G93899SO|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G33570YF |
| T16 | 575-578 | Glycan_Motif | denotes | GD3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G98544DH|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81928IQ |
| T18 | 637-640 | Glycan_Motif | denotes | GD3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G98544DH|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81928IQ |
| T20 | 641-644 | Glycan_Motif | denotes | GT3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G93899SO|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G33570YF |
| T22 | 655-658 | Glycan_Motif | denotes | GD3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G98544DH|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81928IQ |
| T24 | 667-670 | Glycan_Motif | denotes | GD3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G98544DH|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81928IQ |
| T26 | 689-692 | Glycan_Motif | denotes | GT3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G93899SO|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G33570YF |
| T28 | 715-718 | Glycan_Motif | denotes | GM3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G91237TK|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G56516VH |
| T30 | 805-808 | Glycan_Motif | denotes | GD3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G98544DH|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81928IQ |
| T32 | 874-885 | Glycan_Motif | denotes | sialic acid | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY |
| T33 | 976-979 | Glycan_Motif | denotes | GD3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G98544DH|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81928IQ |
| T35 | 985-988 | Glycan_Motif | denotes | GD3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G98544DH|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81928IQ |
| T37 | 1028-1031 | Glycan_Motif | denotes | GT3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G93899SO|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G33570YF |
| T39 | 1102-1105 | Glycan_Motif | denotes | GD3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G98544DH|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81928IQ |
| T41 | 1152-1155 | Glycan_Motif | denotes | GT3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G93899SO|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G33570YF |
| T43 | 1209-1212 | Glycan_Motif | denotes | GD3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G98544DH|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81928IQ |
| T45 | 1213-1216 | Glycan_Motif | denotes | GT3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G93899SO|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G33570YF |
| T47 | 1262-1265 | Glycan_Motif | denotes | GD3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G98544DH|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81928IQ |
| T49 | 1349-1352 | Glycan_Motif | denotes | GD3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G98544DH|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81928IQ |
| T51 | 1558-1561 | Glycan_Motif | denotes | GD3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G98544DH|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81928IQ |
GGDB-2020
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 715-718 | https://acgg.asia/db/ggdb/info/gg052 | denotes | GM3 |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-43 | Sentence | denotes | Expression cloning of a human GT3 synthase. |
| T2 | 44-91 | Sentence | denotes | GD3 AND GT3 are synthesized by a single enzyme. |
| T3 | 92-216 | Sentence | denotes | Gangliosides of the C series such as GT3 are polysialylated glycosphingolipids whose synthesis is developmentally regulated. |
| T4 | 217-493 | Sentence | denotes | Here we report the expression cDNA cloning and characterization of GT3 synthase that adds the second alpha-2,8-sialic acid to GD3, NeuNAcalpha2-->8NeuNAcalpha2-->3Galbeta1-->4Glc-->Cer, thus forming GT3, NeuNAcalpha2-->8NeuNAcalpha2-->8NeuNAc alpha2-->3Galbeta1--> 4Glc-->Cer. |
| T5 | 494-588 | Sentence | denotes | Unexpectedly, the cloned cDNA was found to be identical to the cDNA that encodes GD3 synthase. |
| T6 | 589-666 | Sentence | denotes | The newly identified enzyme was therefore named GD3/GT3 synthase (GD3/GT3ST). |
| T7 | 667-932 | Sentence | denotes | GD3/GT3ST synthesized GT3 most efficiently when GM3, NeuNAcalpha2-->3Galbeta1-->4Glc-->Cer, was incubated as an acceptor, indicating that GD3/GT3ST is a polysialyltransferase that can transfer more than one sialic acid residue via alpha-2,8 linkage to gangliosides. |
| T8 | 933-1065 | Sentence | denotes | Moreover, a longer period of incubation of GD3 with GD3/GT3ST produced a significant amount of GT3 and higher polysialogangliosides. |
| T9 | 1066-1243 | Sentence | denotes | Among various cell lines expressing GD3/GT3ST, higher polysialogangliosides including GT3 were detected only in cell lines where the amount of GD3/GT3 mRNA is sufficiently high. |
| T10 | 1244-1344 | Sentence | denotes | The expression of GD3/GT3ST mRNA among human tissues is highly restricted to fetal and adult brains. |
| T11 | 1345-1417 | Sentence | denotes | The GD3/GT3ST gene was found to be located at chromosome 12, region p12. |
| T12 | 1418-1618 | Sentence | denotes | Taken together, these results indicate that C series polysialogangliosides are synthesized by a ganglioside-specific polysialyltransferase, GD3/GT3ST, that is specifically expressed in neural tissues. |
| T1 | 0-43 | Sentence | denotes | Expression cloning of a human GT3 synthase. |
| T2 | 44-91 | Sentence | denotes | GD3 AND GT3 are synthesized by a single enzyme. |
| T3 | 92-216 | Sentence | denotes | Gangliosides of the C series such as GT3 are polysialylated glycosphingolipids whose synthesis is developmentally regulated. |
| T4 | 217-493 | Sentence | denotes | Here we report the expression cDNA cloning and characterization of GT3 synthase that adds the second alpha-2,8-sialic acid to GD3, NeuNAcalpha2-->8NeuNAcalpha2-->3Galbeta1-->4Glc-->Cer, thus forming GT3, NeuNAcalpha2-->8NeuNAcalpha2-->8NeuNAc alpha2-->3Galbeta1--> 4Glc-->Cer. |
| T5 | 494-588 | Sentence | denotes | Unexpectedly, the cloned cDNA was found to be identical to the cDNA that encodes GD3 synthase. |
| T6 | 589-666 | Sentence | denotes | The newly identified enzyme was therefore named GD3/GT3 synthase (GD3/GT3ST). |
| T7 | 667-932 | Sentence | denotes | GD3/GT3ST synthesized GT3 most efficiently when GM3, NeuNAcalpha2-->3Galbeta1-->4Glc-->Cer, was incubated as an acceptor, indicating that GD3/GT3ST is a polysialyltransferase that can transfer more than one sialic acid residue via alpha-2,8 linkage to gangliosides. |
| T8 | 933-1065 | Sentence | denotes | Moreover, a longer period of incubation of GD3 with GD3/GT3ST produced a significant amount of GT3 and higher polysialogangliosides. |
| T9 | 1066-1243 | Sentence | denotes | Among various cell lines expressing GD3/GT3ST, higher polysialogangliosides including GT3 were detected only in cell lines where the amount of GD3/GT3 mRNA is sufficiently high. |
| T10 | 1244-1344 | Sentence | denotes | The expression of GD3/GT3ST mRNA among human tissues is highly restricted to fetal and adult brains. |
| T11 | 1345-1417 | Sentence | denotes | The GD3/GT3ST gene was found to be located at chromosome 12, region p12. |
| T12 | 1418-1618 | Sentence | denotes | Taken together, these results indicate that C series polysialogangliosides are synthesized by a ganglioside-specific polysialyltransferase, GD3/GT3ST, that is specifically expressed in neural tissues. |
Glycosmos6-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 1337-1343 | http://purl.obolibrary.org/obo/MAT_0000098 | denotes | brains |
GlyCosmos6-Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 30-33 | https://glytoucan.org/Structures/Glycans/G33570YF | denotes | GT3 |
| T2 | 30-33 | https://glytoucan.org/Structures/Glycans/G93899SO | denotes | GT3 |
| T3 | 44-47 | https://glytoucan.org/Structures/Glycans/G81928IQ | denotes | GD3 |
| T4 | 44-47 | https://glytoucan.org/Structures/Glycans/G98544DH | denotes | GD3 |
| T5 | 52-55 | https://glytoucan.org/Structures/Glycans/G33570YF | denotes | GT3 |
| T6 | 52-55 | https://glytoucan.org/Structures/Glycans/G93899SO | denotes | GT3 |
| T7 | 129-132 | https://glytoucan.org/Structures/Glycans/G33570YF | denotes | GT3 |
| T8 | 129-132 | https://glytoucan.org/Structures/Glycans/G93899SO | denotes | GT3 |
| T9 | 284-287 | https://glytoucan.org/Structures/Glycans/G33570YF | denotes | GT3 |
| T10 | 284-287 | https://glytoucan.org/Structures/Glycans/G93899SO | denotes | GT3 |
| T11 | 328-339 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | sialic acid |
| T12 | 343-346 | https://glytoucan.org/Structures/Glycans/G81928IQ | denotes | GD3 |
| T13 | 343-346 | https://glytoucan.org/Structures/Glycans/G98544DH | denotes | GD3 |
| T14 | 416-419 | https://glytoucan.org/Structures/Glycans/G33570YF | denotes | GT3 |
| T15 | 416-419 | https://glytoucan.org/Structures/Glycans/G93899SO | denotes | GT3 |
| T16 | 575-578 | https://glytoucan.org/Structures/Glycans/G81928IQ | denotes | GD3 |
| T17 | 575-578 | https://glytoucan.org/Structures/Glycans/G98544DH | denotes | GD3 |
| T18 | 637-640 | https://glytoucan.org/Structures/Glycans/G81928IQ | denotes | GD3 |
| T19 | 637-640 | https://glytoucan.org/Structures/Glycans/G98544DH | denotes | GD3 |
| T20 | 641-644 | https://glytoucan.org/Structures/Glycans/G33570YF | denotes | GT3 |
| T21 | 641-644 | https://glytoucan.org/Structures/Glycans/G93899SO | denotes | GT3 |
| T22 | 655-658 | https://glytoucan.org/Structures/Glycans/G81928IQ | denotes | GD3 |
| T23 | 655-658 | https://glytoucan.org/Structures/Glycans/G98544DH | denotes | GD3 |
| T24 | 667-670 | https://glytoucan.org/Structures/Glycans/G81928IQ | denotes | GD3 |
| T25 | 667-670 | https://glytoucan.org/Structures/Glycans/G98544DH | denotes | GD3 |
| T26 | 689-692 | https://glytoucan.org/Structures/Glycans/G33570YF | denotes | GT3 |
| T27 | 689-692 | https://glytoucan.org/Structures/Glycans/G93899SO | denotes | GT3 |
| T28 | 715-718 | https://glytoucan.org/Structures/Glycans/G56516VH | denotes | GM3 |
| T29 | 715-718 | https://glytoucan.org/Structures/Glycans/G91237TK | denotes | GM3 |
| T30 | 805-808 | https://glytoucan.org/Structures/Glycans/G81928IQ | denotes | GD3 |
| T31 | 805-808 | https://glytoucan.org/Structures/Glycans/G98544DH | denotes | GD3 |
| T32 | 874-885 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | sialic acid |
| T33 | 976-979 | https://glytoucan.org/Structures/Glycans/G81928IQ | denotes | GD3 |
| T34 | 976-979 | https://glytoucan.org/Structures/Glycans/G98544DH | denotes | GD3 |
| T35 | 985-988 | https://glytoucan.org/Structures/Glycans/G81928IQ | denotes | GD3 |
| T36 | 985-988 | https://glytoucan.org/Structures/Glycans/G98544DH | denotes | GD3 |
| T37 | 1028-1031 | https://glytoucan.org/Structures/Glycans/G33570YF | denotes | GT3 |
| T38 | 1028-1031 | https://glytoucan.org/Structures/Glycans/G93899SO | denotes | GT3 |
| T39 | 1102-1105 | https://glytoucan.org/Structures/Glycans/G81928IQ | denotes | GD3 |
| T40 | 1102-1105 | https://glytoucan.org/Structures/Glycans/G98544DH | denotes | GD3 |
| T41 | 1152-1155 | https://glytoucan.org/Structures/Glycans/G33570YF | denotes | GT3 |
| T42 | 1152-1155 | https://glytoucan.org/Structures/Glycans/G93899SO | denotes | GT3 |
| T43 | 1209-1212 | https://glytoucan.org/Structures/Glycans/G81928IQ | denotes | GD3 |
| T44 | 1209-1212 | https://glytoucan.org/Structures/Glycans/G98544DH | denotes | GD3 |
| T45 | 1213-1216 | https://glytoucan.org/Structures/Glycans/G33570YF | denotes | GT3 |
| T46 | 1213-1216 | https://glytoucan.org/Structures/Glycans/G93899SO | denotes | GT3 |
| T47 | 1262-1265 | https://glytoucan.org/Structures/Glycans/G81928IQ | denotes | GD3 |
| T48 | 1262-1265 | https://glytoucan.org/Structures/Glycans/G98544DH | denotes | GD3 |
| T49 | 1349-1352 | https://glytoucan.org/Structures/Glycans/G81928IQ | denotes | GD3 |
| T50 | 1349-1352 | https://glytoucan.org/Structures/Glycans/G98544DH | denotes | GD3 |
| T51 | 1558-1561 | https://glytoucan.org/Structures/Glycans/G81928IQ | denotes | GD3 |
| T52 | 1558-1561 | https://glytoucan.org/Structures/Glycans/G98544DH | denotes | GD3 |
Glycosmos6-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 30-33 | http://www.glycoepitope.jp/epitopes/EP0070 | denotes | GT3 |
| T2 | 52-55 | http://www.glycoepitope.jp/epitopes/EP0070 | denotes | GT3 |
| T3 | 129-132 | http://www.glycoepitope.jp/epitopes/EP0070 | denotes | GT3 |
| T4 | 284-287 | http://www.glycoepitope.jp/epitopes/EP0070 | denotes | GT3 |
| T5 | 416-419 | http://www.glycoepitope.jp/epitopes/EP0070 | denotes | GT3 |
| T6 | 641-644 | http://www.glycoepitope.jp/epitopes/EP0070 | denotes | GT3 |
| T7 | 689-692 | http://www.glycoepitope.jp/epitopes/EP0070 | denotes | GT3 |
| T8 | 1028-1031 | http://www.glycoepitope.jp/epitopes/EP0070 | denotes | GT3 |
| T9 | 1152-1155 | http://www.glycoepitope.jp/epitopes/EP0070 | denotes | GT3 |
| T10 | 1213-1216 | http://www.glycoepitope.jp/epitopes/EP0070 | denotes | GT3 |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 1337-1343 | Body_part | denotes | brains | http://purl.obolibrary.org/obo/MAT_0000098 |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 30-33 | Glycan | denotes | GT3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G93899SO |
| T2 | 44-47 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
| T3 | 52-55 | Glycan | denotes | GT3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G93899SO |
| T4 | 129-132 | Glycan | denotes | GT3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G93899SO |
| T5 | 284-287 | Glycan | denotes | GT3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G93899SO |
| T6 | 343-346 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
| T7 | 416-419 | Glycan | denotes | GT3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G93899SO |
| T8 | 575-578 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
| T9 | 637-640 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
| T10 | 641-644 | Glycan | denotes | GT3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G93899SO |
| T11 | 655-658 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
| T12 | 667-670 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
| T13 | 689-692 | Glycan | denotes | GT3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G93899SO |
| T14 | 715-718 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T15 | 805-808 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
| T16 | 976-979 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
| T17 | 985-988 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
| T18 | 1028-1031 | Glycan | denotes | GT3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G93899SO |
| T19 | 1102-1105 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
| T20 | 1152-1155 | Glycan | denotes | GT3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G93899SO |
| T21 | 1209-1212 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
| T22 | 1213-1216 | Glycan | denotes | GT3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G93899SO |
| T23 | 1262-1265 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
| T24 | 1349-1352 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
| T25 | 1558-1561 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
GlyCosmos15-NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 24-29 | OrganismTaxon | denotes | human | 9606 |
| T2 | 1283-1288 | OrganismTaxon | denotes | human | 9606 |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 1391-1401 | Body_part | denotes | chromosome | http://purl.obolibrary.org/obo/GO_0005694 |
| T2 | 1603-1617 | Body_part | denotes | neural tissues | http://purl.obolibrary.org/obo/UBERON_0003714 |
GlyCosmos15-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 1337-1343 | Body_part | denotes | brains | http://purl.obolibrary.org/obo/MAT_0000098 |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-43 | Sentence | denotes | Expression cloning of a human GT3 synthase. |
| T2 | 44-91 | Sentence | denotes | GD3 AND GT3 are synthesized by a single enzyme. |
| T3 | 92-216 | Sentence | denotes | Gangliosides of the C series such as GT3 are polysialylated glycosphingolipids whose synthesis is developmentally regulated. |
| T4 | 217-493 | Sentence | denotes | Here we report the expression cDNA cloning and characterization of GT3 synthase that adds the second alpha-2,8-sialic acid to GD3, NeuNAcalpha2-->8NeuNAcalpha2-->3Galbeta1-->4Glc-->Cer, thus forming GT3, NeuNAcalpha2-->8NeuNAcalpha2-->8NeuNAc alpha2-->3Galbeta1--> 4Glc-->Cer. |
| T5 | 494-588 | Sentence | denotes | Unexpectedly, the cloned cDNA was found to be identical to the cDNA that encodes GD3 synthase. |
| T6 | 589-666 | Sentence | denotes | The newly identified enzyme was therefore named GD3/GT3 synthase (GD3/GT3ST). |
| T7 | 667-932 | Sentence | denotes | GD3/GT3ST synthesized GT3 most efficiently when GM3, NeuNAcalpha2-->3Galbeta1-->4Glc-->Cer, was incubated as an acceptor, indicating that GD3/GT3ST is a polysialyltransferase that can transfer more than one sialic acid residue via alpha-2,8 linkage to gangliosides. |
| T8 | 933-1065 | Sentence | denotes | Moreover, a longer period of incubation of GD3 with GD3/GT3ST produced a significant amount of GT3 and higher polysialogangliosides. |
| T9 | 1066-1243 | Sentence | denotes | Among various cell lines expressing GD3/GT3ST, higher polysialogangliosides including GT3 were detected only in cell lines where the amount of GD3/GT3 mRNA is sufficiently high. |
| T10 | 1244-1344 | Sentence | denotes | The expression of GD3/GT3ST mRNA among human tissues is highly restricted to fetal and adult brains. |
| T11 | 1345-1417 | Sentence | denotes | The GD3/GT3ST gene was found to be located at chromosome 12, region p12. |
| T12 | 1418-1618 | Sentence | denotes | Taken together, these results indicate that C series polysialogangliosides are synthesized by a ganglioside-specific polysialyltransferase, GD3/GT3ST, that is specifically expressed in neural tissues. |
| T1 | 0-43 | Sentence | denotes | Expression cloning of a human GT3 synthase. |
| T2 | 44-91 | Sentence | denotes | GD3 AND GT3 are synthesized by a single enzyme. |
| T3 | 92-216 | Sentence | denotes | Gangliosides of the C series such as GT3 are polysialylated glycosphingolipids whose synthesis is developmentally regulated. |
| T4 | 217-493 | Sentence | denotes | Here we report the expression cDNA cloning and characterization of GT3 synthase that adds the second alpha-2,8-sialic acid to GD3, NeuNAcalpha2-->8NeuNAcalpha2-->3Galbeta1-->4Glc-->Cer, thus forming GT3, NeuNAcalpha2-->8NeuNAcalpha2-->8NeuNAc alpha2-->3Galbeta1--> 4Glc-->Cer. |
| T5 | 494-588 | Sentence | denotes | Unexpectedly, the cloned cDNA was found to be identical to the cDNA that encodes GD3 synthase. |
| T6 | 589-666 | Sentence | denotes | The newly identified enzyme was therefore named GD3/GT3 synthase (GD3/GT3ST). |
| T7 | 667-932 | Sentence | denotes | GD3/GT3ST synthesized GT3 most efficiently when GM3, NeuNAcalpha2-->3Galbeta1-->4Glc-->Cer, was incubated as an acceptor, indicating that GD3/GT3ST is a polysialyltransferase that can transfer more than one sialic acid residue via alpha-2,8 linkage to gangliosides. |
| T8 | 933-1065 | Sentence | denotes | Moreover, a longer period of incubation of GD3 with GD3/GT3ST produced a significant amount of GT3 and higher polysialogangliosides. |
| T9 | 1066-1243 | Sentence | denotes | Among various cell lines expressing GD3/GT3ST, higher polysialogangliosides including GT3 were detected only in cell lines where the amount of GD3/GT3 mRNA is sufficiently high. |
| T10 | 1244-1344 | Sentence | denotes | The expression of GD3/GT3ST mRNA among human tissues is highly restricted to fetal and adult brains. |
| T11 | 1345-1417 | Sentence | denotes | The GD3/GT3ST gene was found to be located at chromosome 12, region p12. |
| T12 | 1418-1618 | Sentence | denotes | Taken together, these results indicate that C series polysialogangliosides are synthesized by a ganglioside-specific polysialyltransferase, GD3/GT3ST, that is specifically expressed in neural tissues. |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-43 | Sentence | denotes | Expression cloning of a human GT3 synthase. |
| T2 | 44-91 | Sentence | denotes | GD3 AND GT3 are synthesized by a single enzyme. |
| T3 | 92-216 | Sentence | denotes | Gangliosides of the C series such as GT3 are polysialylated glycosphingolipids whose synthesis is developmentally regulated. |
| T4 | 217-588 | Sentence | denotes | Here we report the expression cDNA cloning and characterization of GT3 synthase that adds the second alpha-2,8-sialic acid to GD3, NeuNAcalpha2-->8NeuNAcalpha2-->3Galbeta1-->4Glc-->Cer, thus forming GT3, NeuNAcalpha2-->8NeuNAcalpha2-->8NeuNAc alpha2-->3Galbeta1--> 4Glc-->Cer. Unexpectedly, the cloned cDNA was found to be identical to the cDNA that encodes GD3 synthase. |
| T5 | 589-666 | Sentence | denotes | The newly identified enzyme was therefore named GD3/GT3 synthase (GD3/GT3ST). |
| T6 | 667-932 | Sentence | denotes | GD3/GT3ST synthesized GT3 most efficiently when GM3, NeuNAcalpha2-->3Galbeta1-->4Glc-->Cer, was incubated as an acceptor, indicating that GD3/GT3ST is a polysialyltransferase that can transfer more than one sialic acid residue via alpha-2,8 linkage to gangliosides. |
| T7 | 933-1065 | Sentence | denotes | Moreover, a longer period of incubation of GD3 with GD3/GT3ST produced a significant amount of GT3 and higher polysialogangliosides. |
| T8 | 1066-1243 | Sentence | denotes | Among various cell lines expressing GD3/GT3ST, higher polysialogangliosides including GT3 were detected only in cell lines where the amount of GD3/GT3 mRNA is sufficiently high. |
| T9 | 1244-1344 | Sentence | denotes | The expression of GD3/GT3ST mRNA among human tissues is highly restricted to fetal and adult brains. |
| T10 | 1345-1417 | Sentence | denotes | The GD3/GT3ST gene was found to be located at chromosome 12, region p12. |
| T11 | 1418-1618 | Sentence | denotes | Taken together, these results indicate that C series polysialogangliosides are synthesized by a ganglioside-specific polysialyltransferase, GD3/GT3ST, that is specifically expressed in neural tissues. |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 30-33 | Glycan | denotes | GT3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G93899SO |
| T2 | 44-47 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
| T3 | 52-55 | Glycan | denotes | GT3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G93899SO |
| T4 | 129-132 | Glycan | denotes | GT3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G93899SO |
| T5 | 284-287 | Glycan | denotes | GT3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G93899SO |
| T6 | 343-346 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
| T7 | 416-419 | Glycan | denotes | GT3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G93899SO |
| T8 | 575-578 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
| T9 | 637-640 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
| T10 | 641-644 | Glycan | denotes | GT3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G93899SO |
| T11 | 655-658 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
| T12 | 667-670 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
| T13 | 689-692 | Glycan | denotes | GT3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G93899SO |
| T14 | 715-718 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T15 | 805-808 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
| T16 | 976-979 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
| T17 | 985-988 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
| T18 | 1028-1031 | Glycan | denotes | GT3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G93899SO |
| T19 | 1102-1105 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
| T20 | 1152-1155 | Glycan | denotes | GT3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G93899SO |
| T21 | 1209-1212 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
| T22 | 1213-1216 | Glycan | denotes | GT3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G93899SO |
| T23 | 1262-1265 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
| T24 | 1349-1352 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
| T25 | 1558-1561 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
GlyCosmos15-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 30-33 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GT3 | http://www.glycoepitope.jp/epitopes/EP0070 |
| T2 | 52-55 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GT3 | http://www.glycoepitope.jp/epitopes/EP0070 |
| T3 | 129-132 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GT3 | http://www.glycoepitope.jp/epitopes/EP0070 |
| T4 | 284-287 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GT3 | http://www.glycoepitope.jp/epitopes/EP0070 |
| T5 | 416-419 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GT3 | http://www.glycoepitope.jp/epitopes/EP0070 |
| T6 | 641-644 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GT3 | http://www.glycoepitope.jp/epitopes/EP0070 |
| T7 | 689-692 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GT3 | http://www.glycoepitope.jp/epitopes/EP0070 |
| T8 | 1028-1031 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GT3 | http://www.glycoepitope.jp/epitopes/EP0070 |
| T9 | 1152-1155 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GT3 | http://www.glycoepitope.jp/epitopes/EP0070 |
| T10 | 1213-1216 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GT3 | http://www.glycoepitope.jp/epitopes/EP0070 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 24-29 | OrganismTaxon | denotes | human | 9606 |
| T2 | 1283-1288 | OrganismTaxon | denotes | human | 9606 |
GlyCosmos-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 30-33 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GT3 | http://www.glycoepitope.jp/epitopes/EP0070 |
| T2 | 52-55 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GT3 | http://www.glycoepitope.jp/epitopes/EP0070 |
| T3 | 129-132 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GT3 | http://www.glycoepitope.jp/epitopes/EP0070 |
| T4 | 284-287 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GT3 | http://www.glycoepitope.jp/epitopes/EP0070 |
| T5 | 416-419 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GT3 | http://www.glycoepitope.jp/epitopes/EP0070 |
| T6 | 641-644 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GT3 | http://www.glycoepitope.jp/epitopes/EP0070 |
| T7 | 689-692 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GT3 | http://www.glycoepitope.jp/epitopes/EP0070 |
| T8 | 1028-1031 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GT3 | http://www.glycoepitope.jp/epitopes/EP0070 |
| T9 | 1152-1155 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GT3 | http://www.glycoepitope.jp/epitopes/EP0070 |
| T10 | 1213-1216 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GT3 | http://www.glycoepitope.jp/epitopes/EP0070 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 1391-1401 | Body_part | denotes | chromosome | http://purl.obolibrary.org/obo/GO_0005694 |
| T2 | 1603-1617 | Body_part | denotes | neural tissues | http://purl.obolibrary.org/obo/UBERON_0003714 |