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PubMed:8621538 JSONTXT

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sentences

Id Subject Object Predicate Lexical cue
T1 0-156 Sentence denotes Interactions of a transcriptional activator in the env gene of the mouse mammary tumor virus with activation-dependent, T cell-specific transacting factors.
T2 157-315 Sentence denotes The mouse mammary tumor virus env gene contains a transcriptional activator (META) that can control transcription of the adjacent long terminal repeat region.
T3 316-513 Sentence denotes Transcriptional control by META parallels that of several lymphokine genes, being specific to T cells, dependent on their activation, and inhibited by the immunosuppressive drug cyclosporine (CsA).
T4 514-711 Sentence denotes DNase I footprinting indicated that nuclear factors from activated T lymphocytes bound a promoter-proximal site, META(P), and a promoter-distal site, META(D+), within the 400-base pair META region.
T5 712-822 Sentence denotes Nuclear factors from unstimulated, but not from activated cells, bound a site, META(D-), adjacent to META(D+).
T6 823-1006 Sentence denotes META(D+) directed transcription of a linked luciferase gene, and gel shift analysis revealed binding of inducible, CsA-sensitive T cell factors, in parallel with transfection results.
T7 1007-1095 Sentence denotes Authentic NFAT and NF-kappaB targets did not compete for the META(D+) binding factor(s).
T8 1096-1236 Sentence denotes The SV40 core sequence competed for META(D+) binding factors, but META(D+) failed to compete for the complexes obtained with the SV40 probe.
T9 1237-1442 Sentence denotes Our results, taken together, indicate that META(D+) is a novel transcriptional enhancer element that is similar in its cell-type specificity, activation dependence, and CsA sensitivity to the NFAT element.
T10 1443-1549 Sentence denotes It may be relevant to the role of MMTV in expression of Mls antigens or the induction of T cell lymphomas.
T1 0-156 Sentence denotes Interactions of a transcriptional activator in the env gene of the mouse mammary tumor virus with activation-dependent, T cell-specific transacting factors.
T2 157-315 Sentence denotes The mouse mammary tumor virus env gene contains a transcriptional activator (META) that can control transcription of the adjacent long terminal repeat region.
T3 316-513 Sentence denotes Transcriptional control by META parallels that of several lymphokine genes, being specific to T cells, dependent on their activation, and inhibited by the immunosuppressive drug cyclosporine (CsA).
T4 514-711 Sentence denotes DNase I footprinting indicated that nuclear factors from activated T lymphocytes bound a promoter-proximal site, META(P), and a promoter-distal site, META(D+), within the 400-base pair META region.
T5 712-822 Sentence denotes Nuclear factors from unstimulated, but not from activated cells, bound a site, META(D-), adjacent to META(D+).
T6 823-1006 Sentence denotes META(D+) directed transcription of a linked luciferase gene, and gel shift analysis revealed binding of inducible, CsA-sensitive T cell factors, in parallel with transfection results.
T7 1007-1095 Sentence denotes Authentic NFAT and NF-kappaB targets did not compete for the META(D+) binding factor(s).
T8 1096-1236 Sentence denotes The SV40 core sequence competed for META(D+) binding factors, but META(D+) failed to compete for the complexes obtained with the SV40 probe.
T9 1237-1442 Sentence denotes Our results, taken together, indicate that META(D+) is a novel transcriptional enhancer element that is similar in its cell-type specificity, activation dependence, and CsA sensitivity to the NFAT element.
T10 1443-1549 Sentence denotes It may be relevant to the role of MMTV in expression of Mls antigens or the induction of T cell lymphomas.

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 612-620 http://purl.obolibrary.org/obo/MAT_0000491 denotes proximal

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 18-43 DNA denotes transcriptional activator
T2 51-59 DNA denotes env gene
T3 98-155 protein denotes activation-dependent, T cell-specific transacting factors
T4 187-195 DNA denotes env gene
T5 207-232 DNA denotes transcriptional activator
T6 234-238 DNA denotes META
T7 287-314 DNA denotes long terminal repeat region
T8 343-347 DNA denotes META
T9 374-390 DNA denotes lymphokine genes
T10 410-417 cell_type denotes T cells
T11 514-521 protein denotes DNase I
T12 550-565 protein denotes nuclear factors
T13 571-594 cell_type denotes activated T lymphocytes
T14 603-625 DNA denotes promoter-proximal site
T15 627-634 DNA denotes META(P)
T16 642-662 DNA denotes promoter-distal site
T17 664-672 DNA denotes META(D+)
T18 685-710 DNA denotes 400-base pair META region
T19 712-727 protein denotes Nuclear factors
T20 791-799 DNA denotes META(D-)
T21 813-821 DNA denotes META(D+)
T22 823-831 DNA denotes META(D+)
T23 867-882 DNA denotes luciferase gene
T24 938-966 protein denotes CsA-sensitive T cell factors
T25 1017-1043 DNA denotes NFAT and NF-kappaB targets
T26 1068-1091 protein denotes META(D+) binding factor
T27 1100-1118 DNA denotes SV40 core sequence
T28 1132-1156 protein denotes META(D+) binding factors
T29 1162-1170 DNA denotes META(D+)
T30 1280-1288 DNA denotes META(D+)
T31 1300-1332 DNA denotes transcriptional enhancer element
T32 1429-1441 DNA denotes NFAT element
T33 1499-1511 protein denotes Mls antigens

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-156 Sentence denotes Interactions of a transcriptional activator in the env gene of the mouse mammary tumor virus with activation-dependent, T cell-specific transacting factors.
S2 157-315 Sentence denotes The mouse mammary tumor virus env gene contains a transcriptional activator (META) that can control transcription of the adjacent long terminal repeat region.
S3 316-513 Sentence denotes Transcriptional control by META parallels that of several lymphokine genes, being specific to T cells, dependent on their activation, and inhibited by the immunosuppressive drug cyclosporine (CsA).
S4 514-711 Sentence denotes DNase I footprinting indicated that nuclear factors from activated T lymphocytes bound a promoter-proximal site, META(P), and a promoter-distal site, META(D+), within the 400-base pair META region.
S5 712-822 Sentence denotes Nuclear factors from unstimulated, but not from activated cells, bound a site, META(D-), adjacent to META(D+).
S6 823-1006 Sentence denotes META(D+) directed transcription of a linked luciferase gene, and gel shift analysis revealed binding of inducible, CsA-sensitive T cell factors, in parallel with transfection results.
S7 1007-1095 Sentence denotes Authentic NFAT and NF-kappaB targets did not compete for the META(D+) binding factor(s).
S8 1096-1236 Sentence denotes The SV40 core sequence competed for META(D+) binding factors, but META(D+) failed to compete for the complexes obtained with the SV40 probe.
S9 1237-1442 Sentence denotes Our results, taken together, indicate that META(D+) is a novel transcriptional enhancer element that is similar in its cell-type specificity, activation dependence, and CsA sensitivity to the NFAT element.
S10 1443-1549 Sentence denotes It may be relevant to the role of MMTV in expression of Mls antigens or the induction of T cell lymphomas.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C2 47-92 NP denotes the env gene of the mouse mammary tumor virus
C1 16-92 NP denotes a transcriptional activator in the env gene of the mouse mammary tumor virus
C3 157-195 NP denotes The mouse mammary tumor virus env gene
C4 205-239 NP denotes a transcriptional activator (META)
C5 240-244 NP denotes that
C6 316-339 NP denotes Transcriptional control
C7 343-347 NP denotes META
C8 358-362 NP denotes that
C9 366-390 NP denotes several lymphokine genes
C10 432-437 NP denotes their
C11 467-512 NP denotes the immunosuppressive drug cyclosporine (CsA)
C12 601-625 NP denotes a promoter-proximal site
C13 627-634 NP denotes META(P)
C14 640-662 NP denotes a promoter-distal site
C15 664-672 NP denotes META(D+)
C16 783-789 NP denotes a site
C17 791-799 NP denotes META(D-)
C18 813-821 NP denotes META(D+)
C19 823-831 NP denotes META(D+)
C20 938-942 NP denotes CsA-
C21 1064-1094 NP denotes the META(D+) binding factor(s)
C22 1132-1156 NP denotes META(D+) binding factors
C23 1162-1170 NP denotes META(D+)
C24 1280-1288 NP denotes META(D+)
C25 1292-1332 NP denotes a novel transcriptional enhancer element
C26 1333-1337 NP denotes that
C27 1352-1355 NP denotes its
R1 C3 C2 coref-ident The mouse mammary tumor virus env gene,the env gene of the mouse mammary tumor virus
R2 C4 C1 coref-ident a transcriptional activator (META),a transcriptional activator in the env gene of the mouse mammary tumor virus
R3 C5 C4 coref-relat that,a transcriptional activator (META)
R4 C7 C4 coref-ident META,a transcriptional activator (META)
R5 C8 C6 coref-pron that,Transcriptional control
R6 C10 C9 coref-pron their,several lymphokine genes
R7 C13 C12 coref-appos META(P),a promoter-proximal site
R8 C15 C14 coref-appos META(D+),a promoter-distal site
R9 C17 C16 coref-appos META(D-),a site
R10 C18 C15 coref-ident META(D+),META(D+)
R11 C19 C18 coref-ident META(D+),META(D+)
R12 C20 C11 coref-ident CsA-,the immunosuppressive drug cyclosporine (CsA)
R13 C22 C21 coref-ident META(D+) binding factors,the META(D+) binding factor(s)
R14 C23 C19 coref-ident META(D+),META(D+)
R15 C24 C23 coref-ident META(D+),META(D+)
R16 C26 C25 coref-relat that,a novel transcriptional enhancer element
R17 C27 C24 coref-pron its,META(D+)

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 18-43 DNA_domain_or_region denotes transcriptional activator
T2 51-59 DNA_domain_or_region denotes env gene
T3 67-92 virus denotes mouse mammary tumor virus
T4 98-155 protein_family_or_group denotes activation-dependent, T cell-specific transacting factors
T5 161-186 virus denotes mouse mammary tumor virus
T6 187-195 DNA_domain_or_region denotes env gene
T7 207-232 DNA_domain_or_region denotes transcriptional activator
T8 234-238 DNA_domain_or_region denotes META
T9 287-314 DNA_domain_or_region denotes long terminal repeat region
T10 343-347 DNA_domain_or_region denotes META
T11 374-390 DNA_family_or_group denotes lymphokine genes
T12 410-417 cell_type denotes T cells
T13 471-493 other_organic_compound denotes immunosuppressive drug
T14 494-506 other_organic_compound denotes cyclosporine
T15 508-511 other_organic_compound denotes CsA
T16 514-521 protein_molecule denotes DNase I
T17 550-565 protein_family_or_group denotes nuclear factors
T18 571-594 cell_type denotes activated T lymphocytes
T19 603-625 DNA_domain_or_region denotes promoter-proximal site
T20 627-634 DNA_domain_or_region denotes META(P)
T21 642-662 DNA_domain_or_region denotes promoter-distal site
T22 664-672 DNA_domain_or_region denotes META(D+)
T23 685-710 DNA_domain_or_region denotes 400-base pair META region
T24 712-727 protein_family_or_group denotes Nuclear factors
T25 791-799 DNA_domain_or_region denotes META(D-)
T26 813-821 DNA_domain_or_region denotes META(D+)
T27 823-831 DNA_domain_or_region denotes META(D+)
T28 867-882 DNA_domain_or_region denotes luciferase gene
T29 888-906 other_name denotes gel shift analysis
T30 938-941 other_organic_compound denotes CsA
T31 985-1005 other_name denotes transfection results
T32 1068-1076 DNA_domain_or_region denotes META(D+)
T33 1100-1118 DNA_domain_or_region denotes SV40 core sequence
T34 1132-1140 DNA_domain_or_region denotes META(D+)
T35 1162-1170 DNA_domain_or_region denotes META(D+)
T36 1225-1235 polynucleotide denotes SV40 probe
T37 1280-1288 DNA_domain_or_region denotes META(D+)
T38 1300-1332 DNA_family_or_group denotes transcriptional enhancer element
T39 1406-1409 other_organic_compound denotes CsA
T40 1429-1441 DNA_domain_or_region denotes NFAT element
T41 1477-1481 virus denotes MMTV
T42 1499-1511 protein_family_or_group denotes Mls antigens
T43 1532-1548 other_name denotes T cell lymphomas

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 612-620 Body_part denotes proximal http://purl.obolibrary.org/obo/MAT_0000491

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 81-86 Phenotype denotes tumor HP:0002664
T2 175-180 Phenotype denotes tumor HP:0002664
T3 1532-1548 Phenotype denotes T cell lymphomas HP:0012190

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 73-86 Disease denotes mammary tumor http://purl.obolibrary.org/obo/MONDO_0007254
T2 167-180 Disease denotes mammary tumor http://purl.obolibrary.org/obo/MONDO_0007254
T3 1532-1548 Disease denotes T cell lymphomas http://purl.obolibrary.org/obo/MONDO_0015760

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 67-92 OrganismTaxon denotes mouse mammary tumor virus 11757
T2 161-186 OrganismTaxon denotes mouse mammary tumor virus 11757

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 120-126 Body_part denotes T cell http://purl.obolibrary.org/obo/CL_0000084
T2 581-594 Body_part denotes T lymphocytes http://purl.obolibrary.org/obo/CL_0000084
T3 952-958 Body_part denotes T cell http://purl.obolibrary.org/obo/CL_0000084
T4 1532-1538 Body_part denotes T cell http://purl.obolibrary.org/obo/CL_0000084

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 120-126 Cell denotes T cell http://purl.obolibrary.org/obo/CL:0000084
T2 410-417 Cell denotes T cells http://purl.obolibrary.org/obo/CL:0000084
T3 581-594 Cell denotes T lymphocytes http://purl.obolibrary.org/obo/CL:0000084
T4 952-958 Cell denotes T cell http://purl.obolibrary.org/obo/CL:0000084
T5 1532-1538 Cell denotes T cell http://purl.obolibrary.org/obo/CL:0000084