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PubMed:8493578 JSONTXT

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DisGeNET

Id Subject Object Predicate Lexical cue
T0 537-542 gene:84337 denotes Elf-1
T1 658-672 disease:C0035335 denotes retinoblastoma
T2 537-542 gene:1943 denotes Elf-1
T3 658-672 disease:C0035335 denotes retinoblastoma
T4 537-542 gene:1997 denotes Elf-1
T5 658-672 disease:C0035335 denotes retinoblastoma
R1 T0 T1 associated_with Elf-1,retinoblastoma
R2 T2 T3 associated_with Elf-1,retinoblastoma
R3 T4 T5 associated_with Elf-1,retinoblastoma

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 18-50 protein denotes Ets-related transcription factor
T2 51-56 protein denotes Elf-1
T3 75-97 protein denotes retinoblastoma protein
T4 103-130 protein denotes retinoblastoma gene product
T5 132-134 protein denotes Rb
T6 141-163 protein denotes nuclear phosphoprotein
T7 203-208 protein denotes Elf-1
T8 214-256 protein denotes lymphoid-specific Ets transcription factor
T9 305-311 cell_type denotes T cell
T10 364-369 protein denotes Elf-1
T11 426-442 protein denotes Rb binding sites
T12 460-472 protein denotes oncoproteins
T13 507-509 protein denotes Rb
T14 537-542 protein denotes Elf-1
T15 596-598 protein denotes Rb
T16 620-630 protein denotes Rb mutants
T17 745-750 protein denotes Elf-1
T18 755-757 protein denotes Rb
T19 761-789 cell_type denotes resting normal human T cells
T20 839-841 protein denotes Rb
T21 868-873 protein denotes Elf-1
T22 929-934 protein denotes Elf-1
T23 1013-1015 protein denotes Rb
T24 1026-1031 protein denotes Elf-1
T25 1063-1069 cell_type denotes T cell
T26 1113-1115 protein denotes Rb
T27 1146-1189 protein denotes lineage-restricted Ets transcription factor
T28 1303-1313 protein denotes lymphokine
T29 1356-1373 cell_type denotes activated T cells

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-98 Sentence denotes Regulation of the Ets-related transcription factor Elf-1 by binding to the retinoblastoma protein.
S2 99-202 Sentence denotes The retinoblastoma gene product (Rb) is a nuclear phosphoprotein that regulates cell cycle progression.
S3 203-323 Sentence denotes Elf-1 is a lymphoid-specific Ets transcription factor that regulates inducible gene expression during T cell activation.
S4 324-536 Sentence denotes In this report, it is demonstrated that Elf-1 contains a sequence motif that is highly related to the Rb binding sites of several viral oncoproteins and binds to the pocket region of Rb both in vitro and in vivo.
S5 537-673 Sentence denotes Elf-1 binds exclusively to the underphosphorylated form of Rb and fails to bind to Rb mutants derived from patients with retinoblastoma.
S6 674-790 Sentence denotes Co-immunoprecipitation experiments demonstrated an association between Elf-1 and Rb in resting normal human T cells.
S7 791-958 Sentence denotes After T cell activation, the phosphorylation of Rb results in the release of Elf-1, which is correlated temporally with the activation of Elf-1-mediated transcription.
S8 959-1081 Sentence denotes Overexpression of a phosphorylation-defective form of Rb inhibited Elf-1-dependent transcription during T cell activation.
S9 1082-1190 Sentence denotes These results demonstrate that Rb interacts specifically with a lineage-restricted Ets transcription factor.
S10 1191-1374 Sentence denotes This regulated interaction may be important for the coordination of lineage-specific effector functions such as lymphokine production with cell cycle progression in activated T cells.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 14-56 NP denotes the Ets-related transcription factor Elf-1
C2 99-135 NP denotes The retinoblastoma gene product (Rb)
C3 179-201 NP denotes cell cycle progression
C4 203-208 NP denotes Elf-1
C5 212-256 NP denotes a lymphoid-specific Ets transcription factor
C6 257-261 NP denotes that
C7 305-322 NP denotes T cell activation
C8 364-369 NP denotes Elf-1
C9 379-395 NP denotes a sequence motif
C10 396-400 NP denotes that
C11 426-428 NP denotes Rb
C12 507-509 NP denotes Rb
C13 537-542 NP denotes Elf-1
C14 596-598 NP denotes Rb
C15 620-622 NP denotes Rb
C16 745-750 NP denotes Elf-1
C17 755-757 NP denotes Rb
C18 797-814 NP denotes T cell activation
C19 839-841 NP denotes Rb
C21 868-873 NP denotes Elf-1
C20 853-873 NP denotes the release of Elf-1
C22 875-880 NP denotes which
C23 929-935 NP denotes Elf-1-
C24 1013-1015 NP denotes Rb
C25 1026-1032 NP denotes Elf-1-
C26 1063-1080 NP denotes T cell activation
C27 1113-1115 NP denotes Rb
C28 1330-1373 NP denotes cell cycle progression in activated T cells
R1 C4 C1 coref-ident Elf-1,the Ets-related transcription factor Elf-1
R2 C6 C5 coref-relat that,a lymphoid-specific Ets transcription factor
R3 C8 C4 coref-ident Elf-1,Elf-1
R4 C10 C9 coref-relat that,a sequence motif
R5 C11 C2 coref-ident Rb,The retinoblastoma gene product (Rb)
R6 C12 C2 coref-ident Rb,The retinoblastoma gene product (Rb)
R7 C13 C8 coref-ident Elf-1,Elf-1
R8 C14 C2 coref-ident Rb,The retinoblastoma gene product (Rb)
R9 C15 C2 coref-ident Rb,The retinoblastoma gene product (Rb)
R10 C16 C13 coref-ident Elf-1,Elf-1
R11 C17 C2 coref-ident Rb,The retinoblastoma gene product (Rb)
R12 C18 C7 coref-ident T cell activation,T cell activation
R13 C19 C2 coref-ident Rb,The retinoblastoma gene product (Rb)
R14 C21 C16 coref-ident Elf-1,Elf-1
R15 C22 C20 coref-relat which,the release of Elf-1
R16 C23 C16 coref-ident Elf-1-,Elf-1
R17 C24 C19 coref-ident Rb,Rb
R18 C25 C23 coref-ident Elf-1-,Elf-1-
R19 C26 C18 coref-ident T cell activation,T cell activation
R20 C27 C24 coref-ident Rb,Rb
R21 C28 C3 coref-other cell cycle progression in activated T cells,cell cycle progression

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 18-50 protein_family_or_group denotes Ets-related transcription factor
T2 51-56 protein_molecule denotes Elf-1
T3 75-97 protein_molecule denotes retinoblastoma protein
T4 103-130 protein_molecule denotes retinoblastoma gene product
T5 132-134 protein_molecule denotes Rb
T6 141-163 protein_family_or_group denotes nuclear phosphoprotein
T7 179-201 other_name denotes cell cycle progression
T8 203-208 protein_molecule denotes Elf-1
T9 214-256 protein_family_or_group denotes lymphoid-specific Ets transcription factor
T10 272-297 other_name denotes inducible gene expression
T11 305-311 cell_type denotes T cell
T12 364-369 protein_molecule denotes Elf-1
T13 426-442 protein_domain_or_region denotes Rb binding sites
T14 460-472 protein_family_or_group denotes oncoproteins
T15 507-509 protein_molecule denotes Rb
T16 537-542 protein_molecule denotes Elf-1
T17 596-598 protein_molecule denotes Rb
T18 620-630 protein_family_or_group denotes Rb mutants
T19 644-652 multi_cell denotes patients
T20 658-672 other_name denotes retinoblastoma
T21 674-708 other_name denotes Co-immunoprecipitation experiments
T22 745-750 protein_molecule denotes Elf-1
T23 755-757 protein_molecule denotes Rb
T24 761-789 cell_type denotes resting normal human T cells
T25 797-814 other_name denotes T cell activation
T26 839-841 protein_molecule denotes Rb
T27 868-873 protein_molecule denotes Elf-1
T28 929-934 protein_molecule denotes Elf-1
T29 1013-1015 protein_molecule denotes Rb
T30 1026-1031 protein_molecule denotes Elf-1
T31 1063-1069 cell_type denotes T cell
T32 1113-1115 protein_molecule denotes Rb
T33 1146-1189 protein_family_or_group denotes lineage-restricted Ets transcription factor
T34 1303-1313 protein_family_or_group denotes lymphokine
T35 1356-1373 cell_type denotes activated T cells

AIMed

Id Subject Object Predicate Lexical cue
T1 18-21 protein denotes Ets
T2 51-56 protein denotes Elf-1
T3 75-89 protein denotes retinoblastoma
T4 103-117 protein denotes retinoblastoma
T5 132-134 protein denotes Rb
T6 203-208 protein denotes Elf-1
T7 232-235 protein denotes Ets
T8 364-369 protein denotes Elf-1
T9 426-428 protein denotes Rb
T10 507-509 protein denotes Rb
T11 537-542 protein denotes Elf-1
T12 596-598 protein denotes Rb
T13 620-622 protein denotes Rb
T14 745-750 protein denotes Elf-1
T15 755-757 protein denotes Rb
T16 839-841 protein denotes Rb
T17 868-873 protein denotes Elf-1
T18 929-934 protein denotes Elf-1
T19 1013-1015 protein denotes Rb
T20 1026-1031 protein denotes Elf-1
T21 1113-1115 protein denotes Rb
T22 1165-1168 protein denotes Ets