| Id |
Subject |
Object |
Predicate |
Lexical cue |
| TextSentencer_T1 |
0-99 |
Sentence |
denotes |
A new approach to the molecular characterization of the c-ANCA antigen in Wegener's granulomatosis. |
| TextSentencer_T2 |
100-310 |
Sentence |
denotes |
Classic anti-neutrophil cytoplasmic antibodies (c-ANCA) specific for constituents of neutrophil primary granules and monocyte lysosomes have been implicated in the pathogenesis of Wegener's Granulomatosis (WG). |
| TextSentencer_T3 |
311-442 |
Sentence |
denotes |
The revised amino-terminal sequence of Proteinase 3 (PR-3) as ANCA antigen, suggested that PR-3 is identical to myeloblastin (MBN). |
| TextSentencer_T4 |
443-608 |
Sentence |
denotes |
As it has been proposed that autoantibodies recognize a conformational epitope on c-ANCA, prokaryotic expressed protein might not be recognized by the patients sera. |
| TextSentencer_T5 |
609-747 |
Sentence |
denotes |
Therefore we set up an in vitro translation in an eukaryotic cell-free system using an internal ATG (amino acid 15 of the mature protein). |
| T1 |
0-99 |
Sentence |
denotes |
A new approach to the molecular characterization of the c-ANCA antigen in Wegener's granulomatosis. |
| T2 |
100-310 |
Sentence |
denotes |
Classic anti-neutrophil cytoplasmic antibodies (c-ANCA) specific for constituents of neutrophil primary granules and monocyte lysosomes have been implicated in the pathogenesis of Wegener's Granulomatosis (WG). |
| T3 |
311-442 |
Sentence |
denotes |
The revised amino-terminal sequence of Proteinase 3 (PR-3) as ANCA antigen, suggested that PR-3 is identical to myeloblastin (MBN). |
| T4 |
443-608 |
Sentence |
denotes |
As it has been proposed that autoantibodies recognize a conformational epitope on c-ANCA, prokaryotic expressed protein might not be recognized by the patients sera. |
| T5 |
609-747 |
Sentence |
denotes |
Therefore we set up an in vitro translation in an eukaryotic cell-free system using an internal ATG (amino acid 15 of the mature protein). |
