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PubMed:8288556 JSONTXT

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sentences

Id Subject Object Predicate Lexical cue
T1 0-93 Sentence denotes Identification of probasin-related antigen as cystathionine gamma-lyase by molecular cloning.
T2 94-257 Sentence denotes We reported previously that a monoclonal antibody against probasin (rat prostatic secretory protein) recognizes a 40-kDa protein localized in rat liver and kidney.
T3 258-376 Sentence denotes The protein (probasin-related antigen, PRB-RA) may participate in a specific differentiated function of these tissues.
T4 377-564 Sentence denotes To clarify the molecular nature of PRB-RA, a series of cDNA clones coding for the protein were isolated from a rat liver expression library using an affinity-purified polyclonal antibody.
T5 565-755 Sentence denotes The amino acid sequence deduced from the determined cDNA sequence included sequences identical with those of proteolytic fragments of PRB-RA, which covered about 70% of the deduced sequence.
T6 756-954 Sentence denotes Northern blot hybridization of poly(A)+ RNA isolated from rat tissues showed the presence of predominant and minor mRNA species of about 2.0 and 4.3 kilobases, respectively, in the liver and kidney.
T7 955-1140 Sentence denotes A sequence homology search revealed that PRB-RA is almost completely identical to rat cystathionine gamma-lyase (cystathionase) and that it does not show overall homology with probasin.
T8 1141-1283 Sentence denotes Three candidates for an epitope common to probasin and PRB-RA were found on close examination of the amino acid sequences of the two proteins.
T9 1284-1474 Sentence denotes A synthetic peptide, TYFRRI, corresponding to one of the candidates, neutralized the reactivity of the anti-probasin monoclonal antibody to both probasin and PRB-RA on Western blot analysis.
T10 1475-1796 Sentence denotes These results show that PRB-RA/cystathionase is neither structurally nor functionally related to probasin except for a common epitope and that cystathionase, a cystein-producing enzyme, is localized in urinary tubular epithelial cells in a highly restricted region of the kidney in addition to in liver parenchymal cells.
T1 0-93 Sentence denotes Identification of probasin-related antigen as cystathionine gamma-lyase by molecular cloning.
T2 94-257 Sentence denotes We reported previously that a monoclonal antibody against probasin (rat prostatic secretory protein) recognizes a 40-kDa protein localized in rat liver and kidney.
T3 258-376 Sentence denotes The protein (probasin-related antigen, PRB-RA) may participate in a specific differentiated function of these tissues.
T4 377-564 Sentence denotes To clarify the molecular nature of PRB-RA, a series of cDNA clones coding for the protein were isolated from a rat liver expression library using an affinity-purified polyclonal antibody.
T5 565-755 Sentence denotes The amino acid sequence deduced from the determined cDNA sequence included sequences identical with those of proteolytic fragments of PRB-RA, which covered about 70% of the deduced sequence.
T6 756-954 Sentence denotes Northern blot hybridization of poly(A)+ RNA isolated from rat tissues showed the presence of predominant and minor mRNA species of about 2.0 and 4.3 kilobases, respectively, in the liver and kidney.
T7 955-1140 Sentence denotes A sequence homology search revealed that PRB-RA is almost completely identical to rat cystathionine gamma-lyase (cystathionase) and that it does not show overall homology with probasin.
T8 1141-1283 Sentence denotes Three candidates for an epitope common to probasin and PRB-RA were found on close examination of the amino acid sequences of the two proteins.
T9 1284-1474 Sentence denotes A synthetic peptide, TYFRRI, corresponding to one of the candidates, neutralized the reactivity of the anti-probasin monoclonal antibody to both probasin and PRB-RA on Western blot analysis.
T10 1475-1796 Sentence denotes These results show that PRB-RA/cystathionase is neither structurally nor functionally related to probasin except for a common epitope and that cystathionase, a cystein-producing enzyme, is localized in urinary tubular epithelial cells in a highly restricted region of the kidney in addition to in liver parenchymal cells.

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 166-175 http://purl.obolibrary.org/obo/MAT_0000078 denotes prostatic
T2 240-245 http://purl.obolibrary.org/obo/MAT_0000097 denotes liver
T3 250-256 http://purl.obolibrary.org/obo/MAT_0000119 denotes kidney
T4 492-497 http://purl.obolibrary.org/obo/MAT_0000097 denotes liver
T5 937-942 http://purl.obolibrary.org/obo/MAT_0000097 denotes liver
T6 947-953 http://purl.obolibrary.org/obo/MAT_0000119 denotes kidney
T7 1747-1753 http://purl.obolibrary.org/obo/MAT_0000119 denotes kidney
T8 1772-1777 http://purl.obolibrary.org/obo/MAT_0000097 denotes liver

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 166-175 Body_part denotes prostatic http://purl.obolibrary.org/obo/MAT_0000078
T2 240-245 Body_part denotes liver http://purl.obolibrary.org/obo/MAT_0000097
T3 250-256 Body_part denotes kidney http://purl.obolibrary.org/obo/MAT_0000119
T4 492-497 Body_part denotes liver http://purl.obolibrary.org/obo/MAT_0000097
T5 937-942 Body_part denotes liver http://purl.obolibrary.org/obo/MAT_0000097
T6 947-953 Body_part denotes kidney http://purl.obolibrary.org/obo/MAT_0000119
T7 1747-1753 Body_part denotes kidney http://purl.obolibrary.org/obo/MAT_0000119
T8 1772-1777 Body_part denotes liver http://purl.obolibrary.org/obo/MAT_0000097

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 301-303 Phenotype denotes RA HP:0001370
T2 416-418 Phenotype denotes RA HP:0001370
T3 703-705 Phenotype denotes RA HP:0001370
T4 1000-1002 Phenotype denotes RA HP:0001370
T5 1200-1202 Phenotype denotes RA HP:0001370
T6 1446-1448 Phenotype denotes RA HP:0001370
T7 1503-1505 Phenotype denotes RA HP:0001370

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 162-165 OrganismTaxon denotes rat 10114|10116
T3 236-239 OrganismTaxon denotes rat 10114|10116
T5 488-491 OrganismTaxon denotes rat 10114|10116
T7 814-817 OrganismTaxon denotes rat 10114|10116
T9 1037-1040 OrganismTaxon denotes rat 10114|10116

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 240-245 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T2 250-256 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T3 492-497 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T4 937-942 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T5 947-953 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T6 1693-1709 Body_part denotes epithelial cells http://purl.obolibrary.org/obo/CL_0000066
T7 1747-1753 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T8 1772-1789 Body_part denotes liver parenchymal http://purl.obolibrary.org/obo/UBERON_0001280

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 787-791 Cell denotes poly http://purl.obolibrary.org/obo/CL:0000096|http://purl.obolibrary.org/obo/CL:0000775
T3 1693-1709 Cell denotes epithelial cells http://purl.obolibrary.org/obo/CL:0000066