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PubMed:8085155 JSONTXT

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Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-57 Sentence denotes An interleukin-4-induced transcription factor: IL-4 Stat.
T2 58-174 Sentence denotes Interleukin-4 (IL-4) is an immunomodulatory cytokine secreted by activated T lymphocytes, basophils, and mast cells.
T3 175-313 Sentence denotes It plays an important role in modulating the balance of T helper (Th) cell subsets, favoring expansion of the Th2 lineage relative to Th1.
T4 314-456 Sentence denotes Imbalance of these T lymphocyte subsets has been implicated in immunological diseases including allergy, inflammation, and autoimmune disease.
T5 457-576 Sentence denotes IL-4 may mediate its biological effects, at least in part, by activating a tyrosine-phosphorylated DNA binding protein.
T6 577-641 Sentence denotes This protein has now been purified and its encoding gene cloned.
T7 642-860 Sentence denotes Examination of the primary amino acid sequence of this protein indicates that it is a member of the signal transducers and activators of transcription (Stat) family of DNA binding proteins, hereby designated IL-4 Stat.
T8 861-1107 Sentence denotes Study of the inhibitory activities of phosphotyrosine-containing peptides derived from the intracellular domain of the IL-4 receptor provided evidence for direct coupling of receptor and transcription factor during the IL-4 Stat activation cycle.
T9 1108-1225 Sentence denotes Such observations indicate that IL-4 Stat has the same functional domain for both receptor coupling and dimerization.
T1 0-57 Sentence denotes An interleukin-4-induced transcription factor: IL-4 Stat.
T2 58-174 Sentence denotes Interleukin-4 (IL-4) is an immunomodulatory cytokine secreted by activated T lymphocytes, basophils, and mast cells.
T3 175-313 Sentence denotes It plays an important role in modulating the balance of T helper (Th) cell subsets, favoring expansion of the Th2 lineage relative to Th1.
T4 314-456 Sentence denotes Imbalance of these T lymphocyte subsets has been implicated in immunological diseases including allergy, inflammation, and autoimmune disease.
T5 457-576 Sentence denotes IL-4 may mediate its biological effects, at least in part, by activating a tyrosine-phosphorylated DNA binding protein.
T6 577-641 Sentence denotes This protein has now been purified and its encoding gene cloned.
T7 642-860 Sentence denotes Examination of the primary amino acid sequence of this protein indicates that it is a member of the signal transducers and activators of transcription (Stat) family of DNA binding proteins, hereby designated IL-4 Stat.
T8 861-1107 Sentence denotes Study of the inhibitory activities of phosphotyrosine-containing peptides derived from the intracellular domain of the IL-4 receptor provided evidence for direct coupling of receptor and transcription factor during the IL-4 Stat activation cycle.
T9 1108-1225 Sentence denotes Such observations indicate that IL-4 Stat has the same functional domain for both receptor coupling and dimerization.

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 3-45 protein denotes interleukin-4-induced transcription factor
T2 47-56 protein denotes IL-4 Stat
T3 58-71 protein denotes Interleukin-4
T4 73-77 protein denotes IL-4
T5 133-146 cell_type denotes T lymphocytes
T6 148-157 cell_type denotes basophils
T7 163-173 cell_type denotes mast cells
T8 231-257 cell_type denotes T helper (Th) cell subsets
T9 285-296 cell_type denotes Th2 lineage
T10 309-312 cell_type denotes Th1
T11 333-353 cell_type denotes T lymphocyte subsets
T12 457-461 protein denotes IL-4
T13 532-575 protein denotes tyrosine-phosphorylated DNA binding protein
T14 742-806 protein denotes signal transducers and activators of transcription (Stat) family
T15 810-830 protein denotes DNA binding proteins
T16 850-859 protein denotes IL-4 Stat
T17 952-993 protein denotes intracellular domain of the IL-4 receptor
T18 1035-1043 protein denotes receptor
T19 1048-1068 protein denotes transcription factor
T20 1080-1089 protein denotes IL-4 Stat
T21 1140-1149 protein denotes IL-4 Stat
T22 1163-1180 protein denotes functional domain

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-57 Sentence denotes An interleukin-4-induced transcription factor: IL-4 Stat.
S2 58-174 Sentence denotes Interleukin-4 (IL-4) is an immunomodulatory cytokine secreted by activated T lymphocytes, basophils, and mast cells.
S3 175-313 Sentence denotes It plays an important role in modulating the balance of T helper (Th) cell subsets, favoring expansion of the Th2 lineage relative to Th1.
S4 314-456 Sentence denotes Imbalance of these T lymphocyte subsets has been implicated in immunological diseases including allergy, inflammation, and autoimmune disease.
S5 457-576 Sentence denotes IL-4 may mediate its biological effects, at least in part, by activating a tyrosine-phosphorylated DNA binding protein.
S6 577-641 Sentence denotes This protein has now been purified and its encoding gene cloned.
S7 642-860 Sentence denotes Examination of the primary amino acid sequence of this protein indicates that it is a member of the signal transducers and activators of transcription (Stat) family of DNA binding proteins, hereby designated IL-4 Stat.
S8 861-1107 Sentence denotes Study of the inhibitory activities of phosphotyrosine-containing peptides derived from the intracellular domain of the IL-4 receptor provided evidence for direct coupling of receptor and transcription factor during the IL-4 Stat activation cycle.
S9 1108-1225 Sentence denotes Such observations indicate that IL-4 Stat has the same functional domain for both receptor coupling and dimerization.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 0-45 NP denotes An interleukin-4-induced transcription factor
C2 47-56 NP denotes IL-4 Stat
C3 58-78 NP denotes Interleukin-4 (IL-4)
C4 175-177 NP denotes It
C5 231-257 NP denotes T helper (Th) cell subsets
C6 327-353 NP denotes these T lymphocyte subsets
C7 457-461 NP denotes IL-4
C8 474-477 NP denotes its
C9 530-575 NP denotes a tyrosine-phosphorylated DNA binding protein
C10 577-589 NP denotes This protein
C11 616-619 NP denotes its
C12 692-704 NP denotes this protein
C13 720-722 NP denotes it
C14 726-830 NP denotes a member of the signal transducers and activators of transcription (Stat) family of DNA binding proteins
C15 850-859 NP denotes IL-4 Stat
C16 1140-1149 NP denotes IL-4 Stat
R1 C2 C1 coref-ident IL-4 Stat,An interleukin-4-induced transcription factor
R2 C4 C3 coref-pron It,Interleukin-4 (IL-4)
R3 C6 C5 coref-ident these T lymphocyte subsets,T helper (Th) cell subsets
R4 C7 C3 coref-ident IL-4,Interleukin-4 (IL-4)
R5 C8 C7 coref-pron its,IL-4
R6 C10 C9 coref-ident This protein,a tyrosine-phosphorylated DNA binding protein
R7 C11 C10 coref-pron its,This protein
R8 C12 C10 coref-ident this protein,This protein
R9 C13 C12 coref-pron it,this protein
R10 C15 C14 coref-ident IL-4 Stat,a member of the signal transducers and activators of transcription (Stat) family of DNA binding proteins
R11 C16 C15 coref-ident IL-4 Stat,IL-4 Stat

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 3-45 protein_family_or_group denotes interleukin-4-induced transcription factor
T2 47-56 protein_molecule denotes IL-4 Stat
T3 58-71 protein_molecule denotes Interleukin-4
T4 73-77 protein_molecule denotes IL-4
T5 133-146 cell_type denotes T lymphocytes
T6 148-157 cell_type denotes basophils
T7 163-173 cell_type denotes mast cells
T8 231-257 cell_type denotes T helper (Th) cell subsets
T9 285-296 cell_type denotes Th2 lineage
T10 309-312 cell_type denotes Th1
T11 333-353 cell_type denotes T lymphocyte subsets
T12 410-417 other_name denotes allergy
T13 419-431 other_name denotes inflammation
T14 437-455 other_name denotes autoimmune disease
T15 457-461 protein_molecule denotes IL-4
T16 532-575 protein_molecule denotes tyrosine-phosphorylated DNA binding protein
T17 742-806 protein_family_or_group denotes signal transducers and activators of transcription (Stat) family
T18 810-830 protein_family_or_group denotes DNA binding proteins
T19 850-859 protein_molecule denotes IL-4 Stat
T20 899-934 peptide denotes phosphotyrosine-containing peptides
T21 952-979 protein_domain_or_region denotes intracellular domain of the
T22 980-984 protein_molecule denotes IL-4
T23 1035-1043 protein_family_or_group denotes receptor
T24 1048-1068 protein_family_or_group denotes transcription factor
T25 1080-1089 protein_molecule denotes IL-4 Stat
T26 1140-1149 protein_molecule denotes IL-4 Stat
T27 1163-1180 protein_domain_or_region denotes functional domain
T28 1190-1207 other_name denotes receptor coupling
T29 1212-1224 other_name denotes dimerization