PubMed:8052854 JSONTXT

{"project":"Inflammaging","denotations":[{"id":"T1","span":{"begin":0,"end":58},"obj":"Sentence"},{"id":"T2","span":{"begin":59,"end":298},"obj":"Sentence"},{"id":"T3","span":{"begin":299,"end":459},"obj":"Sentence"},{"id":"T4","span":{"begin":460,"end":595},"obj":"Sentence"},{"id":"T5","span":{"begin":596,"end":796},"obj":"Sentence"},{"id":"T1","span":{"begin":0,"end":58},"obj":"Sentence"},{"id":"T2","span":{"begin":59,"end":298},"obj":"Sentence"},{"id":"T3","span":{"begin":299,"end":459},"obj":"Sentence"},{"id":"T4","span":{"begin":460,"end":595},"obj":"Sentence"},{"id":"T5","span":{"begin":596,"end":796},"obj":"Sentence"}],"text":"Inhibition of NF-kappa B by sodium salicylate and aspirin.\nThe transcription factor nuclear factor-kappa B (NF-kappa B) is critical for the inducible expression of multiple cellular and viral genes involved in inflammation and infection including interleukin-1 (IL-1), IL-6, and adhesion molecules. The anti-inflammatory drugs sodium salicylate and aspirin inhibited the activation of NF-kappa B, which further explains the mechanism of action of these drugs. This inhibition prevented the degradation of the NF-kappa B inhibitor, I kappa B, and therefore NF-kappa B was retained in the cytosol. Sodium salicylate and aspirin also inhibited NF-kappa B-dependent transcription from the Ig kappa enhancer and the human immunodeficiency virus (HIV) long terminal repeat (LTR) in transfected T cells."}

{"project":"jnlpba-st-training","denotations":[{"id":"T1","span":{"begin":14,"end":24},"obj":"protein"},{"id":"T2","span":{"begin":63,"end":83},"obj":"protein"},{"id":"T3","span":{"begin":84,"end":106},"obj":"protein"},{"id":"T4","span":{"begin":108,"end":118},"obj":"protein"},{"id":"T5","span":{"begin":173,"end":197},"obj":"DNA"},{"id":"T6","span":{"begin":247,"end":260},"obj":"protein"},{"id":"T7","span":{"begin":262,"end":266},"obj":"protein"},{"id":"T8","span":{"begin":269,"end":273},"obj":"protein"},{"id":"T9","span":{"begin":279,"end":297},"obj":"protein"},{"id":"T10","span":{"begin":385,"end":395},"obj":"protein"},{"id":"T11","span":{"begin":509,"end":529},"obj":"protein"},{"id":"T12","span":{"begin":531,"end":540},"obj":"protein"},{"id":"T13","span":{"begin":556,"end":566},"obj":"protein"},{"id":"T14","span":{"begin":641,"end":651},"obj":"protein"},{"id":"T15","span":{"begin":685,"end":702},"obj":"DNA"},{"id":"T16","span":{"begin":711,"end":766},"obj":"DNA"},{"id":"T17","span":{"begin":768,"end":771},"obj":"DNA"},{"id":"T18","span":{"begin":776,"end":795},"obj":"cell_line"}],"text":"Inhibition of NF-kappa B by sodium salicylate and aspirin.\nThe transcription factor nuclear factor-kappa B (NF-kappa B) is critical for the inducible expression of multiple cellular and viral genes involved in inflammation and infection including interleukin-1 (IL-1), IL-6, and adhesion molecules. The anti-inflammatory drugs sodium salicylate and aspirin inhibited the activation of NF-kappa B, which further explains the mechanism of action of these drugs. This inhibition prevented the degradation of the NF-kappa B inhibitor, I kappa B, and therefore NF-kappa B was retained in the cytosol. Sodium salicylate and aspirin also inhibited NF-kappa B-dependent transcription from the Ig kappa enhancer and the human immunodeficiency virus (HIV) long terminal repeat (LTR) in transfected T cells."}

{"project":"pubmed-sentences-benchmark","denotations":[{"id":"S1","span":{"begin":0,"end":58},"obj":"Sentence"},{"id":"S2","span":{"begin":59,"end":298},"obj":"Sentence"},{"id":"S3","span":{"begin":299,"end":459},"obj":"Sentence"},{"id":"S4","span":{"begin":460,"end":595},"obj":"Sentence"},{"id":"S5","span":{"begin":596,"end":796},"obj":"Sentence"}],"text":"Inhibition of NF-kappa B by sodium salicylate and aspirin.\nThe transcription factor nuclear factor-kappa B (NF-kappa B) is critical for the inducible expression of multiple cellular and viral genes involved in inflammation and infection including interleukin-1 (IL-1), IL-6, and adhesion molecules. The anti-inflammatory drugs sodium salicylate and aspirin inhibited the activation of NF-kappa B, which further explains the mechanism of action of these drugs. This inhibition prevented the degradation of the NF-kappa B inhibitor, I kappa B, and therefore NF-kappa B was retained in the cytosol. Sodium salicylate and aspirin also inhibited NF-kappa B-dependent transcription from the Ig kappa enhancer and the human immunodeficiency virus (HIV) long terminal repeat (LTR) in transfected T cells."}

{"project":"genia-medco-coref","denotations":[{"id":"C2","span":{"begin":14,"end":24},"obj":"NP"},{"id":"C3","span":{"begin":28,"end":57},"obj":"NP"},{"id":"C1","span":{"begin":0,"end":57},"obj":"NP"},{"id":"C4","span":{"begin":299,"end":356},"obj":"NP"},{"id":"C6","span":{"begin":385,"end":395},"obj":"NP"},{"id":"C5","span":{"begin":367,"end":395},"obj":"NP"},{"id":"C7","span":{"begin":397,"end":402},"obj":"NP"},{"id":"C8","span":{"begin":447,"end":458},"obj":"NP"},{"id":"C9","span":{"begin":460,"end":475},"obj":"NP"},{"id":"C10","span":{"begin":505,"end":529},"obj":"NP"},{"id":"C11","span":{"begin":531,"end":540},"obj":"NP"},{"id":"C12","span":{"begin":556,"end":566},"obj":"NP"},{"id":"C13","span":{"begin":596,"end":625},"obj":"NP"}],"relations":[{"id":"R1","pred":"coref-ident","subj":"C4","obj":"C3"},{"id":"R2","pred":"coref-ident","subj":"C6","obj":"C2"},{"id":"R3","pred":"coref-relat","subj":"C7","obj":"C5"},{"id":"R4","pred":"coref-ident","subj":"C8","obj":"C4"},{"id":"R5","pred":"coref-ident","subj":"C9","obj":"C1"},{"id":"R6","pred":"coref-appos","subj":"C11","obj":"C10"},{"id":"R7","pred":"coref-ident","subj":"C12","obj":"C6"},{"id":"R8","pred":"coref-ident","subj":"C13","obj":"C4"}],"text":"Inhibition of NF-kappa B by sodium salicylate and aspirin.\nThe transcription factor nuclear factor-kappa B (NF-kappa B) is critical for the inducible expression of multiple cellular and viral genes involved in inflammation and infection including interleukin-1 (IL-1), IL-6, and adhesion molecules. The anti-inflammatory drugs sodium salicylate and aspirin inhibited the activation of NF-kappa B, which further explains the mechanism of action of these drugs. This inhibition prevented the degradation of the NF-kappa B inhibitor, I kappa B, and therefore NF-kappa B was retained in the cytosol. Sodium salicylate and aspirin also inhibited NF-kappa B-dependent transcription from the Ig kappa enhancer and the human immunodeficiency virus (HIV) long terminal repeat (LTR) in transfected T cells."}

{"project":"GENIAcorpus","denotations":[{"id":"T1","span":{"begin":14,"end":24},"obj":"protein_molecule"},{"id":"T2","span":{"begin":28,"end":45},"obj":"other_organic_compound"},{"id":"T3","span":{"begin":50,"end":57},"obj":"other_organic_compound"},{"id":"T4","span":{"begin":63,"end":83},"obj":"protein_family_or_group"},{"id":"T5","span":{"begin":84,"end":106},"obj":"protein_molecule"},{"id":"T6","span":{"begin":108,"end":118},"obj":"protein_molecule"},{"id":"T7","span":{"begin":247,"end":260},"obj":"protein_molecule"},{"id":"T8","span":{"begin":262,"end":266},"obj":"protein_molecule"},{"id":"T9","span":{"begin":269,"end":273},"obj":"protein_molecule"},{"id":"T10","span":{"begin":279,"end":297},"obj":"protein_family_or_group"},{"id":"T11","span":{"begin":303,"end":326},"obj":"other_organic_compound"},{"id":"T12","span":{"begin":327,"end":344},"obj":"other_organic_compound"},{"id":"T13","span":{"begin":349,"end":356},"obj":"other_organic_compound"},{"id":"T14","span":{"begin":385,"end":395},"obj":"protein_molecule"},{"id":"T15","span":{"begin":509,"end":519},"obj":"protein_molecule"},{"id":"T16","span":{"begin":531,"end":540},"obj":"protein_molecule"},{"id":"T17","span":{"begin":556,"end":566},"obj":"protein_molecule"},{"id":"T18","span":{"begin":587,"end":594},"obj":"cell_component"},{"id":"T19","span":{"begin":596,"end":613},"obj":"other_organic_compound"},{"id":"T20","span":{"begin":618,"end":625},"obj":"other_organic_compound"},{"id":"T21","span":{"begin":641,"end":651},"obj":"protein_molecule"},{"id":"T22","span":{"begin":685,"end":702},"obj":"DNA_domain_or_region"},{"id":"T23","span":{"begin":711,"end":766},"obj":"DNA_domain_or_region"},{"id":"T24","span":{"begin":768,"end":771},"obj":"DNA_domain_or_region"},{"id":"T25","span":{"begin":776,"end":795},"obj":"cell_line"}],"text":"Inhibition of NF-kappa B by sodium salicylate and aspirin.\nThe transcription factor nuclear factor-kappa B (NF-kappa B) is critical for the inducible expression of multiple cellular and viral genes involved in inflammation and infection including interleukin-1 (IL-1), IL-6, and adhesion molecules. The anti-inflammatory drugs sodium salicylate and aspirin inhibited the activation of NF-kappa B, which further explains the mechanism of action of these drugs. This inhibition prevented the degradation of the NF-kappa B inhibitor, I kappa B, and therefore NF-kappa B was retained in the cytosol. Sodium salicylate and aspirin also inhibited NF-kappa B-dependent transcription from the Ig kappa enhancer and the human immunodeficiency virus (HIV) long terminal repeat (LTR) in transfected T cells."}