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jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 10-23 protein denotes interleukin 2
T2 41-59 cell_type denotes murine lymphocytes
T3 160-173 protein denotes interleukin 2
T4 175-179 protein denotes IL-2
T5 185-201 protein denotes interferon-gamma
T6 203-212 protein denotes IFN-gamma
T7 228-262 cell_type denotes human peripheral blood lymphocytes
T8 312-316 protein denotes IL-2
T9 321-330 RNA denotes IL-2 mRNA
T10 378-393 protein denotes T cell mitogens
T11 397-409 protein denotes alloantigens
T12 411-429 cell_type denotes murine splenocytes
T13 452-475 cell_line denotes murine T cell line EL-4
T14 604-621 cell_type denotes human lymphocytes
T15 623-632 protein denotes IFN-gamma
T16 662-676 RNA denotes IFN-gamma mRNA
T17 767-785 cell_type denotes murine splenocytes
T18 827-837 cell_type denotes EL-4 cells
T19 885-898 DNA denotes IL-2 promoter
T20 903-918 DNA denotes enhancer region
T21 933-986 DNA denotes chloramphenicol acetyltransferase (CAT) reporter gene
T22 1000-1003 protein denotes CAT
T23 1076-1086 cell_type denotes EL-4 cells
T24 1174-1191 cell_type denotes activated T cells
T25 1193-1199 protein denotes NFAT-1
T26 1276-1305 protein denotes nuclear transcription factors
T27 1306-1310 protein denotes AP-1
T28 1314-1321 protein denotes NFIL-2A
T29 1355-1364 protein denotes IFN-gamma
T30 1389-1393 protein denotes IL-2
T31 1408-1426 cell_type denotes murine lymphocytes
T32 1451-1457 protein denotes NFAT-1
T33 1483-1487 protein denotes IL-2

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-77 Sentence denotes Increased interleukin 2 transcription in murine lymphocytes by ciprofloxacin.
S2 78-263 Sentence denotes The fluoroquinolone antibiotic, ciprofloxacin (cipro), induces hyperproduction of interleukin 2 (IL-2) and interferon-gamma (IFN-gamma) in stimulated human peripheral blood lymphocytes.
S3 264-579 Sentence denotes In this investigation an enhanced and prolonged IL-2 and IL-2 mRNA response was also detected in both stimulated (T cell mitogens or alloantigens) murine splenocytes and in the stimulated murine T cell line EL-4 in the presence of ciprofloxacin (5-80 micrograms/ml) as compared to control cells without antibiotics.
S4 580-826 Sentence denotes However, in contrast to human lymphocytes, IFN-gamma production was inhibited and IFN-gamma mRNA levels were unaffected at 24 h and only slightly upregulated at 48 and 72 h of culture in murine splenocytes incubated with cipro (20 micrograms/ml).
S5 827-987 Sentence denotes EL-4 cells were transfected with a plasmid containing the IL-2 promoter and enhancer region linked to the chloramphenicol acetyltransferase (CAT) reporter gene.
S6 988-1062 Sentence denotes Analysis of CAT activity revealed that cipro enhanced IL-2 gene induction.
S7 1063-1250 Sentence denotes In addition, EL-4 cells incubated with ciprofloxacin showed an early peak and more activated nuclear factor of activated T cells (NFAT-1) as compared to control cells without antibiotics.
S8 1251-1322 Sentence denotes Cipro did not affect the nuclear transcription factors AP-1 or NFIL-2A.
S9 1323-1502 Sentence denotes Taken together, cipro inhibited IFN-gamma synthesis, but enhanced IL-2 production in murine lymphocytes by means of influencing NFAT-1 and causing an increased IL-2 transcription.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C2 41-59 NP denotes murine lymphocytes
C3 63-76 NP denotes ciprofloxacin
C1 0-76 NP denotes Increased interleukin 2 transcription in murine lymphocytes by ciprofloxacin
C4 78-108 NP denotes The fluoroquinolone antibiotic
C5 110-131 NP denotes ciprofloxacin (cipro)
C6 545-578 NP denotes control cells without antibiotics
C7 801-806 NP denotes cipro
C8 827-837 NP denotes EL-4 cells
C9 1027-1032 NP denotes cipro
C10 1076-1086 NP denotes EL-4 cells
C11 1216-1249 NP denotes control cells without antibiotics
C12 1251-1256 NP denotes Cipro
C13 1339-1344 NP denotes cipro
C14 1408-1426 NP denotes murine lymphocytes
C15 1470-1501 NP denotes an increased IL-2 transcription
R1 C4 C3 coref-ident The fluoroquinolone antibiotic,ciprofloxacin
R2 C5 C4 coref-appos ciprofloxacin (cipro),The fluoroquinolone antibiotic
R3 C7 C5 coref-ident cipro,ciprofloxacin (cipro)
R4 C9 C7 coref-ident cipro,cipro
R5 C10 C8 coref-ident EL-4 cells,EL-4 cells
R6 C11 C6 coref-ident control cells without antibiotics,control cells without antibiotics
R7 C12 C9 coref-ident Cipro,cipro
R8 C13 C12 coref-ident cipro,Cipro
R9 C14 C2 coref-ident murine lymphocytes,murine lymphocytes
R10 C15 C1 coref-ident an increased IL-2 transcription,Increased interleukin 2 transcription in murine lymphocytes by ciprofloxacin

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 10-23 protein_molecule denotes interleukin 2
T2 41-59 cell_type denotes murine lymphocytes
T3 63-76 other_organic_compound denotes ciprofloxacin
T4 82-108 other_organic_compound denotes fluoroquinolone antibiotic
T5 110-123 other_organic_compound denotes ciprofloxacin
T6 125-130 other_organic_compound denotes cipro
T7 160-173 protein_molecule denotes interleukin 2
T8 175-179 protein_molecule denotes IL-2
T9 185-201 protein_molecule denotes interferon-gamma
T10 203-212 protein_molecule denotes IFN-gamma
T11 228-262 cell_type denotes human peripheral blood lymphocytes
T12 312-316 protein_molecule denotes IL-2
T13 321-330 RNA_molecule denotes IL-2 mRNA
T14 378-393 protein_family_or_group denotes T cell mitogens
T15 397-409 protein_family_or_group denotes alloantigens
T16 411-429 cell_type denotes murine splenocytes
T17 452-475 cell_line denotes murine T cell line EL-4
T18 495-508 other_organic_compound denotes ciprofloxacin
T19 567-578 other_organic_compound denotes antibiotics
T20 604-621 cell_type denotes human lymphocytes
T21 623-632 protein_molecule denotes IFN-gamma
T22 662-671 protein_molecule denotes IFN-gamma
T23 767-785 cell_type denotes murine splenocytes
T24 801-806 other_organic_compound denotes cipro
T25 827-837 cell_type denotes EL-4 cells
T26 885-898 DNA_domain_or_region denotes IL-2 promoter
T27 903-918 DNA_domain_or_region denotes enhancer region
T28 933-966 protein_molecule denotes chloramphenicol acetyltransferase
T29 968-971 protein_molecule denotes CAT
T30 1000-1003 protein_molecule denotes CAT
T31 1027-1032 other_organic_compound denotes cipro
T32 1076-1086 cell_type denotes EL-4 cells
T33 1102-1115 other_organic_compound denotes ciprofloxacin
T34 1174-1191 cell_type denotes activated T cells
T35 1193-1199 protein_molecule denotes NFAT-1
T36 1238-1249 other_organic_compound denotes antibiotics
T37 1276-1305 protein_family_or_group denotes nuclear transcription factors
T38 1306-1310 protein_molecule denotes AP-1
T39 1314-1321 protein_molecule denotes NFIL-2A
T40 1339-1344 other_organic_compound denotes cipro
T41 1355-1364 protein_molecule denotes IFN-gamma
T42 1389-1393 protein_molecule denotes IL-2
T43 1408-1426 cell_type denotes murine lymphocytes
T44 1451-1457 protein_molecule denotes NFAT-1
T45 1483-1487 protein_molecule denotes IL-2