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jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 71-155 DNA denotes colony-stimulating factor 1 (macrophage colony-stimulating factor) receptor promoter
T2 166-175 protein denotes PEBP2/CBF
T3 177-181 protein denotes AML1
T4 205-241 protein denotes macrophage colony-stimulating factor
T5 246-273 protein denotes colony-stimulating factor 1
T6 275-280 protein denotes CSF-1
T7 324-339 cell_type denotes monocytic cells
T8 344-366 cell_type denotes placental trophoblasts
T9 434-448 protein denotes CSF-1 receptor
T10 497-521 DNA denotes tissue-specific promoter
T11 558-603 protein denotes monocyte/B-cell-specific transcription factor
T12 604-608 protein denotes PU.1
T13 757-765 DNA denotes promoter
T14 801-810 DNA denotes region II
T15 839-853 DNA denotes 10 bp upstream
T16 863-880 DNA denotes PU.1-binding site
T17 899-904 protein denotes DNase
T18 919-928 DNA denotes region II
T19 961-976 cell_type denotes monocytic cells
T20 1031-1040 DNA denotes region II
T21 1069-1085 protein denotes nuclear proteins
T22 1091-1106 cell_type denotes monocytic cells
T23 1112-1131 protein denotes gel shift complexes
T24 1133-1139 protein denotes Mono A
T25 1144-1150 protein denotes Mono B
T26 1269-1275 protein denotes Mono B
T27 1301-1380 protein denotes polyomavirus enhancer-binding protein 2/core-binding factor (PEBP2/CBF) family,
T28 1425-1431 protein denotes Mono A
T29 1482-1497 cell_type denotes monocytic cells
T30 1499-1518 DNA denotes Promoter constructs
T31 1602-1611 cell_type denotes monocytes
T32 1626-1666 DNA denotes multimerized region II sequence elements
T33 1736-1751 cell_type denotes monocytic cells
T34 1817-1862 protein denotes monocyte/B-cell-specific transcription factor
T35 1863-1867 protein denotes PU.1
T36 1876-1911 protein denotes Mono A and Mono B protein complexes
T37 1978-1992 protein denotes CSF-1 receptor

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 18-26 NP denotes a region
C2 27-32 NP denotes which
C3 184-282 NP denotes The receptor for the macrophage colony-stimulating factor (or colony-stimulating factor 1 [CSF-1])
C4 324-339 NP denotes monocytic cells
C6 430-448 NP denotes the CSF-1 receptor
C5 394-448 NP denotes the monocyte-specific expression of the CSF-1 receptor
C7 495-521 NP denotes a tissue-specific promoter
C8 522-527 NP denotes whose
C9 554-608 NP denotes the monocyte/B-cell-specific transcription factor PU.1
C10 752-765 NP denotes this promoter
C11 799-826 NP denotes a region II (bp -88 to -59)
C12 828-833 NP denotes which
C13 919-928 NP denotes region II
C14 961-976 NP denotes monocytic cells
C15 1031-1040 NP denotes region II
C16 1091-1106 NP denotes monocytic cells
C17 1108-1151 NP denotes Two gel shift complexes (Mono A and Mono B)
C19 1203-1214 NP denotes this region
C18 1169-1214 NP denotes separate sequence elements within this region
C20 1297-1379 NP denotes the polyomavirus enhancer-binding protein 2/core-binding factor (PEBP2/CBF) family
C21 1381-1386 NP denotes which
C22 1482-1497 NP denotes monocytic cells
C23 1537-1560 NP denotes these sequence elements
C24 1736-1751 NP denotes monocytic cells
C25 1813-1867 NP denotes the monocyte/B-cell-specific transcription factor PU.1
C26 1872-1911 NP denotes the Mono A and Mono B protein complexes
C28 1974-1992 NP denotes the CSF-1 receptor
C27 1939-1992 NP denotes monocyte-specific transcription of the CSF-1 receptor
R1 C2 C1 coref-relat which,a region
R2 C6 C3 coref-ident the CSF-1 receptor,The receptor for the macrophage colony-stimulating factor (or colony-stimulating factor 1 [CSF-1])
R3 C8 C7 coref-relat whose,a tissue-specific promoter
R4 C10 C7 coref-ident this promoter,a tissue-specific promoter
R5 C12 C11 coref-relat which,a region II (bp -88 to -59)
R6 C13 C11 coref-ident region II,a region II (bp -88 to -59)
R7 C14 C4 coref-ident monocytic cells,monocytic cells
R8 C15 C13 coref-ident region II,region II
R9 C16 C14 coref-ident monocytic cells,monocytic cells
R10 C19 C15 coref-ident this region,region II
R11 C21 C20 coref-relat which,the polyomavirus enhancer-binding protein 2/core-binding factor (PEBP2/CBF) family
R12 C22 C16 coref-ident monocytic cells,monocytic cells
R13 C23 C18 coref-ident these sequence elements,separate sequence elements within this region
R14 C24 C22 coref-ident monocytic cells,monocytic cells
R15 C25 C9 coref-ident the monocyte/B-cell-specific transcription factor PU.1,the monocyte/B-cell-specific transcription factor PU.1
R16 C26 C17 coref-ident the Mono A and Mono B protein complexes,Two gel shift complexes (Mono A and Mono B)
R17 C28 C6 coref-ident the CSF-1 receptor,the CSF-1 receptor
R18 C27 C5 coref-ident monocyte-specific transcription of the CSF-1 receptor,the monocyte-specific expression of the CSF-1 receptor

semrep-sample

Id Subject Object Predicate Lexical cue
E1-ti-1 20-26 cui:C0205147 denotes region
E2-ti-1 45-54 cui:C0026473 denotes monocytic
E3-ti-1 55-63 cui:C0439167 denotes activity
E4-ti-1 71-98 cui:C0079784 denotes colony-stimulating factor 1
E5-ti-1 100-136 cui:C0079784 denotes macrophage colony-stimulating factor
E6-ti-1 138-146 cui:C0597357 denotes receptor
E7-ti-1 166-175 cui:C0669679 denotes PEBP2/CBF
E8-ti-1 166-175 cui:C0212320 denotes PEBP2/CBF
E9-ti-1 177-181 cui:C0215508 denotes AML1
T1 166-181 ISA denotes PEBP2/CBF (AML1
T2 160-165 INTERACTS_WITH denotes binds
T3 166-181 INTERACTS_WITH denotes PEBP2/CBF (AML1
E1-ab-1 188-196 cui:C0597357 denotes receptor
E2-ab-1 205-241 cui:C0079784 denotes macrophage colony-stimulating factor
E3-ab-1 246-273 cui:C0079784 denotes colony-stimulating factor 1
E4-ab-1 275-280 cui:C0079784 denotes CSF-1
E5-ab-1 301-310 cui:C1547020 denotes different
E6-ab-1 311-320 cui:C0086860 denotes promoters
E7-ab-1 324-333 cui:C0026473 denotes monocytic
E8-ab-1 334-339 cui:C0007634 denotes cells
E9-ab-1 344-353 cui:C0230956 denotes placental
E10-ab-1 354-366 cui:C0041178 denotes trophoblasts
T4 321-323 LOCATION_OF denotes in
T5 321-323 LOCATION_OF denotes in
T6 344-366 PART_OF denotes placental trophoblasts
E1-ab-2 398-406 cui:C0026473 denotes monocyte
E2-ab-2 416-426 cui:C0185117 denotes expression
E3-ab-2 434-448 cui:C0080092 denotes CSF-1 receptor
E4-ab-2 478-491 cui:C0040649 denotes transcription
E5-ab-2 528-536 cui:C0439167 denotes activity
E6-ab-2 567-603 cui:C0167636 denotes B-cell-specific transcription factor
E7-ab-2 558-608 cui:C0079785 denotes monocyte/B-cell-specific transcription factor PU.1
T7 452-461 AFFECTS denotes regulated
E1-ab-5 648-652 cui:C0999213 denotes Chen
E2-ab-5 658-661 cui:C0719614 denotes D.G
E1-ab-6 670-673 cui:C0324740 denotes Mol
E1-ab-7 675-679 cui:C0007634 denotes Cell
E1-ab-10 737-748 cui:C0037791 denotes specificity
E2-ab-10 786-795 cui:C0162326 denotes sequences
E3-ab-10 801-807 cui:C0205147 denotes region
E4-ab-10 845-853 cui:C0522505 denotes upstream
E5-ab-10 868-880 cui:C0005456 denotes binding site
E1-ab-11 899-904 cui:C0011519 denotes DNase
E2-ab-11 919-925 cui:C0205147 denotes region
E3-ab-11 961-970 cui:C0026473 denotes monocytic
E4-ab-11 971-976 cui:C0007634 denotes cells
E1-ab-12 978-1015 cui:C0949632 denotes Electrophoretic mobility shift assays
E2-ab-12 1031-1037 cui:C0205147 denotes region
E3-ab-12 1069-1085 cui:C0028589 denotes nuclear proteins
E4-ab-12 1091-1100 cui:C0026473 denotes monocytic
E5-ab-12 1101-1106 cui:C0007634 denotes cells
T8 1086-1090 LOCATION_OF denotes from
E1-ab-13 1108-1111 cui:C0205448 denotes Two
E2-ab-13 1112-1115 cui:C0017243 denotes gel
E3-ab-13 1122-1131 cui:C0439855 denotes complexes
E4-ab-13 1169-1177 cui:C0443299 denotes separate
E5-ab-13 1178-1186 cui:C1519249 denotes sequence
E6-ab-13 1187-1195 cui:C0013879 denotes elements
E7-ab-13 1208-1214 cui:C0205147 denotes region
E1-ab-14 1216-1227 cui:C0679932 denotes Competition
E2-ab-14 1243-1254 cui:C0681814 denotes experiments
E3-ab-14 1287-1293 cui:C0680022 denotes member
E4-ab-14 1301-1340 cui:C0212320 denotes polyomavirus enhancer-binding protein 2
E5-ab-14 1341-1345 cui:C1167518 denotes core
E6-ab-14 1354-1360 cui:C1521761 denotes factor
E7-ab-14 1373-1379 cui:C0015576 denotes family
E8-ab-14 1400-1404 cui:C1335654 denotes AML1
E9-ab-14 1405-1417 cui:C0033684 denotes gene product
E10-ab-14 1446-1453 cui:C0439855 denotes complex
E11-ab-14 1482-1491 cui:C0026473 denotes monocytic
E12-ab-14 1492-1497 cui:C0007634 denotes cells
T9 1400-1417 ISA denotes AML1 gene product
T10 1469-1478 PART_OF denotes expressed
T11 1400-1417 PART_OF denotes AML1 gene product
E1-ab-15 1524-1533 cui:C0026882 denotes mutations
E2-ab-15 1543-1551 cui:C1519249 denotes sequence
E3-ab-15 1552-1560 cui:C0013879 denotes elements
E4-ab-15 1569-1575 cui:C0205166 denotes longer
E5-ab-15 1602-1611 cui:C0026473 denotes monocytes
E1-ab-16 1639-1645 cui:C0205147 denotes region
E2-ab-16 1649-1657 cui:C1519249 denotes sequence
E3-ab-16 1658-1666 cui:C0013879 denotes elements
E4-ab-16 1680-1688 cui:C0439167 denotes activity
E5-ab-16 1694-1706 cui:C0439860 denotes heterologous
E6-ab-16 1707-1723 cui:C0040078 denotes thymidine kinase
E7-ab-16 1736-1745 cui:C0026473 denotes monocytic
E8-ab-16 1746-1751 cui:C0007634 denotes cells
E9-ab-16 1756-1759 cui:C1518422 denotes not
E10-ab-16 1766-1776 cui:C0007634 denotes cell types
T12 1733-1735 LOCATION_OF denotes in
E1-ab-17 1791-1798 cui:C1274040 denotes results
E2-ab-17 1826-1862 cui:C0167636 denotes B-cell-specific transcription factor
E3-ab-17 1817-1867 cui:C0079785 denotes monocyte/B-cell-specific transcription factor PU.1
E4-ab-17 1894-1911 cui:C1180347 denotes protein complexes
E5-ab-17 1939-1947 cui:C0026473 denotes monocyte
E6-ab-17 1957-1970 cui:C0040649 denotes transcription
E7-ab-17 1978-1992 cui:C0080092 denotes CSF-1 receptor
T13 1930-1938 INTERACTS_WITH denotes regulate
R1 E9-ti-1 T1 subjectOf AML1,PEBP2/CBF (AML1
R2 E8-ti-1 T1 objectOf PEBP2/CBF,PEBP2/CBF (AML1
R3 E4-ti-1 T2 subjectOf colony-stimulating factor 1,binds
R4 E8-ti-1 T2 objectOf PEBP2/CBF,binds
R5 E4-ti-1 T3 subjectOf colony-stimulating factor 1,PEBP2/CBF (AML1
R6 E9-ti-1 T3 objectOf AML1,PEBP2/CBF (AML1
R7 E8-ab-1 T4 subjectOf cells,in
R8 E2-ab-1 T4 objectOf macrophage colony-stimulating factor,in
R9 E10-ab-1 T5 subjectOf trophoblasts,in
R10 E2-ab-1 T5 objectOf macrophage colony-stimulating factor,in
R11 E10-ab-1 T6 subjectOf trophoblasts,placental trophoblasts
R12 E9-ab-1 T6 objectOf placental,placental trophoblasts
R13 E3-ab-2 T7 subjectOf CSF-1 receptor,regulated
R14 E4-ab-2 T7 objectOf transcription,regulated
R15 E5-ab-12 T8 subjectOf cells,from
R16 E3-ab-12 T8 objectOf nuclear proteins,from
R17 E8-ab-14 T9 subjectOf AML1,AML1 gene product
R18 E9-ab-14 T9 objectOf gene product,AML1 gene product
R19 E9-ab-14 T10 subjectOf gene product,expressed
R20 E12-ab-14 T10 objectOf cells,expressed
R21 E8-ab-14 T11 subjectOf AML1,AML1 gene product
R22 E12-ab-14 T11 objectOf cells,AML1 gene product
R23 E8-ab-16 T12 subjectOf cells,in
R24 E6-ab-16 T12 objectOf thymidine kinase,in
R25 E4-ab-17 T13 subjectOf protein complexes,regulate
R26 E7-ab-17 T13 objectOf CSF-1 receptor,regulate

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-183 Sentence denotes Identification of a region which directs the monocytic activity of the colony-stimulating factor 1 (macrophage colony-stimulating factor) receptor promoter and binds PEBP2/CBF (AML1).
S2 184-367 Sentence denotes The receptor for the macrophage colony-stimulating factor (or colony-stimulating factor 1 [CSF-1]) is expressed from different promoters in monocytic cells and placental trophoblasts.
S3 368-705 Sentence denotes We have demonstrated that the monocyte-specific expression of the CSF-1 receptor is regulated at the level of transcription by a tissue-specific promoter whose activity is stimulated by the monocyte/B-cell-specific transcription factor PU.1 (D.-E. Zhang, C.J. Hetherington, H.-M. Chen, and D.G. Tenen, Mol. Cell. Biol. 14:373-381, 1994).
S4 706-881 Sentence denotes Here we report that the tissue specificity of this promoter is also mediated by sequences in a region II (bp -88 to -59), which lies 10 bp upstream from the PU.1-binding site.
S5 882-977 Sentence denotes When analyzed by DNase footprinting, region II was protected preferentially in monocytic cells.
S6 978-1107 Sentence denotes Electrophoretic mobility shift assays confirmed that region II interacts specifically with nuclear proteins from monocytic cells.
S7 1108-1215 Sentence denotes Two gel shift complexes (Mono A and Mono B) were formed with separate sequence elements within this region.
S8 1216-1498 Sentence denotes Competition and supershift experiments indicate that Mono B contains a member of the polyomavirus enhancer-binding protein 2/core-binding factor (PEBP2/CBF) family, which includes the AML1 gene product, while Mono A is a distinct complex preferentially expressed in monocytic cells.
S9 1499-1612 Sentence denotes Promoter constructs with mutations in these sequence elements were no longer expressed specifically in monocytes.
S10 1613-1784 Sentence denotes Furthermore, multimerized region II sequence elements enhanced the activity of a heterologous thymidine kinase promoter in monocytic cells but not other cell types tested.
S11 1785-1993 Sentence denotes These results indicate that the monocyte/B-cell-specific transcription factor PU.1 and the Mono A and Mono B protein complexes act in concert to regulate monocyte-specific transcription of the CSF-1 receptor.

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 45-63 other_name denotes monocytic activity
T2 71-98 protein_molecule denotes colony-stimulating factor 1
T3 100-136 protein_molecule denotes macrophage colony-stimulating factor
T4 138-155 DNA_domain_or_region denotes receptor promoter
T5 166-175 protein_molecule denotes PEBP2/CBF
T6 177-181 protein_molecule denotes AML1
T7 205-241 protein_molecule denotes macrophage colony-stimulating factor
T8 246-273 protein_molecule denotes colony-stimulating factor 1
T9 275-280 protein_molecule denotes CSF-1
T10 324-339 cell_type denotes monocytic cells
T11 344-366 cell_type denotes placental trophoblasts
T12 398-426 other_name denotes monocyte-specific expression
T13 434-439 protein_molecule denotes CSF-1
T14 497-521 DNA_domain_or_region denotes tissue-specific promoter
T15 558-603 protein_family_or_group denotes monocyte/B-cell-specific transcription factor
T16 604-608 protein_molecule denotes PU.1
T17 757-765 DNA_domain_or_region denotes promoter
T18 801-810 DNA_domain_or_region denotes region II
T19 839-853 DNA_domain_or_region denotes 10 bp upstream
T20 863-867 protein_molecule denotes PU.1
T21 899-904 protein_molecule denotes DNase
T22 919-928 DNA_domain_or_region denotes region II
T23 961-976 cell_type denotes monocytic cells
T24 978-1015 other_name denotes Electrophoretic mobility shift assays
T25 1031-1040 DNA_domain_or_region denotes region II
T26 1069-1085 protein_family_or_group denotes nuclear proteins
T27 1091-1106 cell_type denotes monocytic cells
T28 1112-1131 protein_complex denotes gel shift complexes
T29 1133-1139 protein_complex denotes Mono A
T30 1144-1150 protein_complex denotes Mono B
T31 1216-1227 other_name denotes Competition
T32 1232-1254 other_name denotes supershift experiments
T33 1269-1275 protein_complex denotes Mono B
T34 1301-1362 protein_family_or_group denotes polyomavirus enhancer-binding protein 2/core-binding factor (
T35 1362-1371 protein_molecule denotes PEBP2/CBF
T36 1425-1431 protein_molecule denotes Mono A
T37 1482-1497 cell_type denotes monocytic cells
T38 1499-1518 DNA_molecule denotes Promoter constructs
T39 1602-1611 cell_type denotes monocytes
T40 1626-1638 DNA_domain_or_region denotes multimerized
T41 1639-1648 DNA_domain_or_region denotes region II
T42 1694-1732 DNA_substructure denotes heterologous thymidine kinase promoter
T43 1736-1751 cell_type denotes monocytic cells
T44 1817-1862 protein_family_or_group denotes monocyte/B-cell-specific transcription factor
T45 1863-1867 protein_molecule denotes PU.1
T46 1939-1970 other_name denotes monocyte-specific transcription
T47 1978-1983 protein_molecule denotes CSF-1