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PubMed:7929820 JSONTXT

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Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-62 Sentence denotes C/EBP beta regulation of the tumor necrosis factor alpha gene.
T2 63-166 Sentence denotes Activated macrophages contribute to chronic inflammation by the secretion of cytokines and proteinases.
T3 167-351 Sentence denotes Tumor necrosis factor alpha (TNF alpha) is particularly important in this process because of its ability to regulate other inflammatory mediators in an autocrine and paracrine fashion.
T4 352-445 Sentence denotes The mechanism(s) responsible for the cell type-specific regulation of TNF alpha is not known.
T5 446-564 Sentence denotes We present data to show that the expression of TNF alpha is regulated by the transcription factor C/EBP beta (NF-IL6).
T6 565-726 Sentence denotes C/EBP beta activated the TNF alpha gene promoter in cotransfection assays and bound to it at a site which failed to bind the closely related protein C/EBP alpha.
T7 727-833 Sentence denotes Finally, a dominant-negative version of C/EBP beta blocked TNF alpha promoter activation in myeloid cells.
T8 834-930 Sentence denotes Our results implicate C/EBP beta as an important regulator of TNF alpha by myelomonocytic cells.
T1 0-62 Sentence denotes C/EBP beta regulation of the tumor necrosis factor alpha gene.
T2 63-166 Sentence denotes Activated macrophages contribute to chronic inflammation by the secretion of cytokines and proteinases.
T3 167-351 Sentence denotes Tumor necrosis factor alpha (TNF alpha) is particularly important in this process because of its ability to regulate other inflammatory mediators in an autocrine and paracrine fashion.
T4 352-445 Sentence denotes The mechanism(s) responsible for the cell type-specific regulation of TNF alpha is not known.
T5 446-564 Sentence denotes We present data to show that the expression of TNF alpha is regulated by the transcription factor C/EBP beta (NF-IL6).
T6 565-726 Sentence denotes C/EBP beta activated the TNF alpha gene promoter in cotransfection assays and bound to it at a site which failed to bind the closely related protein C/EBP alpha.
T7 727-833 Sentence denotes Finally, a dominant-negative version of C/EBP beta blocked TNF alpha promoter activation in myeloid cells.
T8 834-930 Sentence denotes Our results implicate C/EBP beta as an important regulator of TNF alpha by myelomonocytic cells.

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 0-10 protein denotes C/EBP beta
T2 29-61 DNA denotes tumor necrosis factor alpha gene
T3 63-84 cell_type denotes Activated macrophages
T4 140-149 protein denotes cytokines
T5 154-165 protein denotes proteinases
T6 167-194 protein denotes Tumor necrosis factor alpha
T7 196-205 protein denotes TNF alpha
T8 422-431 protein denotes TNF alpha
T9 493-502 protein denotes TNF alpha
T10 523-543 protein denotes transcription factor
T11 544-554 protein denotes C/EBP beta
T12 556-562 protein denotes NF-IL6
T13 565-575 protein denotes C/EBP beta
T14 590-613 DNA denotes TNF alpha gene promoter
T15 714-725 protein denotes C/EBP alpha
T16 767-777 protein denotes C/EBP beta
T17 786-804 DNA denotes TNF alpha promoter
T18 819-832 cell_type denotes myeloid cells
T19 856-866 protein denotes C/EBP beta
T20 896-905 protein denotes TNF alpha
T21 909-929 cell_type denotes myelomonocytic cells

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 25-61 NP denotes the tumor necrosis factor alpha gene
C2 99-165 NP denotes chronic inflammation by the secretion of cytokines and proteinases
C3 167-206 NP denotes Tumor necrosis factor alpha (TNF alpha)
C4 236-248 NP denotes this process
C5 260-263 NP denotes its
C6 422-431 NP denotes TNF alpha
C7 493-502 NP denotes TNF alpha
C8 519-563 NP denotes the transcription factor C/EBP beta (NF-IL6)
C9 565-575 NP denotes C/EBP beta
C10 586-613 NP denotes the TNF alpha gene promoter
C11 652-654 NP denotes it
C12 658-664 NP denotes a site
C13 665-670 NP denotes which
C14 767-777 NP denotes C/EBP beta
C15 819-832 NP denotes myeloid cells
C16 856-866 NP denotes C/EBP beta
C17 896-905 NP denotes TNF alpha
C18 909-929 NP denotes myelomonocytic cells
R1 C3 C1 coref-ident Tumor necrosis factor alpha (TNF alpha),the tumor necrosis factor alpha gene
R2 C4 C2 coref-ident this process,chronic inflammation by the secretion of cytokines and proteinases
R3 C5 C3 coref-pron its,Tumor necrosis factor alpha (TNF alpha)
R4 C6 C3 coref-ident TNF alpha,Tumor necrosis factor alpha (TNF alpha)
R5 C7 C6 coref-ident TNF alpha,TNF alpha
R6 C9 C8 coref-ident C/EBP beta,the transcription factor C/EBP beta (NF-IL6)
R7 C11 C10 coref-pron it,the TNF alpha gene promoter
R8 C13 C12 coref-relat which,a site
R9 C14 C9 coref-ident C/EBP beta,C/EBP beta
R10 C16 C14 coref-ident C/EBP beta,C/EBP beta
R11 C17 C7 coref-ident TNF alpha,TNF alpha
R12 C18 C15 coref-ident myelomonocytic cells,myeloid cells

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-62 Sentence denotes C/EBP beta regulation of the tumor necrosis factor alpha gene.
S2 63-166 Sentence denotes Activated macrophages contribute to chronic inflammation by the secretion of cytokines and proteinases.
S3 167-351 Sentence denotes Tumor necrosis factor alpha (TNF alpha) is particularly important in this process because of its ability to regulate other inflammatory mediators in an autocrine and paracrine fashion.
S4 352-445 Sentence denotes The mechanism(s) responsible for the cell type-specific regulation of TNF alpha is not known.
S5 446-564 Sentence denotes We present data to show that the expression of TNF alpha is regulated by the transcription factor C/EBP beta (NF-IL6).
S6 565-726 Sentence denotes C/EBP beta activated the TNF alpha gene promoter in cotransfection assays and bound to it at a site which failed to bind the closely related protein C/EBP alpha.
S7 727-833 Sentence denotes Finally, a dominant-negative version of C/EBP beta blocked TNF alpha promoter activation in myeloid cells.
S8 834-930 Sentence denotes Our results implicate C/EBP beta as an important regulator of TNF alpha by myelomonocytic cells.

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 0-10 protein_molecule denotes C/EBP beta
T2 29-56 protein_molecule denotes tumor necrosis factor alpha
T3 63-84 cell_type denotes Activated macrophages
T4 99-119 other_name denotes chronic inflammation
T5 140-149 protein_family_or_group denotes cytokines
T6 154-165 protein_family_or_group denotes proteinases
T7 167-194 protein_molecule denotes Tumor necrosis factor alpha
T8 196-205 protein_molecule denotes TNF alpha
T9 290-312 other_name denotes inflammatory mediators
T10 389-418 other_name denotes cell type-specific regulation
T11 422-431 protein_molecule denotes TNF alpha
T12 493-502 protein_molecule denotes TNF alpha
T13 523-543 protein_family_or_group denotes transcription factor
T14 544-554 protein_molecule denotes C/EBP beta
T15 556-562 protein_molecule denotes NF-IL6
T16 565-575 protein_molecule denotes C/EBP beta
T17 590-599 protein_molecule denotes TNF alpha
T18 617-638 other_name denotes cotransfection assays
T19 714-725 protein_molecule denotes C/EBP alpha
T20 767-777 protein_molecule denotes C/EBP beta
T21 786-795 protein_molecule denotes TNF alpha
T22 819-832 cell_type denotes myeloid cells
T23 856-866 protein_molecule denotes C/EBP beta
T24 896-905 protein_molecule denotes TNF alpha
T25 909-929 cell_type denotes myelomonocytic cells