> top > docs > PubMed:7815555 > annotations

PubMed:7815555 JSONTXT

Annnotations TAB JSON ListView MergeView

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 24-33 DNA denotes CD48 gene
T2 86-130 cell_type denotes Epstein-Barr virus-immortalized B-cell lines
T3 157-172 DNA denotes NF-kappa B site
T4 220-235 cell_type denotes resting B cells
T5 329-333 protein denotes CD48
T6 367-391 cell_type denotes normal activated B cells
T7 437-453 DNA denotes enhancer element
T8 461-470 DNA denotes CD48 gene
T9 538-578 cell_line denotes EBV-positive B-lymphoblastoid cell lines
T10 639-664 cell_line denotes EBV-negative B-cell lines
T11 724-748 cell_type denotes lymphoblastoid phenotype
T12 753-763 protein denotes NF-kappa B
T13 937-960 protein denotes nuclear protein complex
T14 1001-1012 protein denotes NF-kappa B1
T15 1014-1017 protein denotes p50
T16 1050-1087 protein denotes EBV-encoded latent membrane protein 1
T17 1131-1135 protein denotes CD48
T18 1136-1151 DNA denotes NF-kappa B site
T19 1164-1178 DNA denotes intact element
T20 1200-1225 protein denotes latent membrane protein 1
T21 1247-1261 protein denotes NF-kappa B/Rel
T22 1361-1376 cell_type denotes resting B cells

DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
7815555-1#155#159#gene962 329-333 gene962 denotes CD48
7815555-1#20#34#diseaseC0149678 194-208 diseaseC0149678 denotes EBV) infection
155#159#gene96220#34#diseaseC0149678 7815555-1#155#159#gene962 7815555-1#20#34#diseaseC0149678 associated_with CD48,EBV) infection

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-173 Sentence denotes Characterization of the CD48 gene demonstrates a positive element that is specific to Epstein-Barr virus-immortalized B-cell lines and contains an essential NF-kappa B site.
S2 174-392 Sentence denotes Epstein-Barr virus (EBV) infection of mature, resting B cells drives them to become lymphoblasts expressing high levels of cell surface molecules, such as CD48, characteristically expressed on normal activated B cells.
S3 393-579 Sentence denotes Here, we report on the identification of an enhancer element in the CD48 gene which reproducibly confers strong transcriptional activity only in EBV-positive B-lymphoblastoid cell lines.
S4 580-749 Sentence denotes The element is not activated upon infection of established EBV-negative B-cell lines, indicating that EBV fails to drive these cells to a fully lymphoblastoid phenotype.
S5 750-908 Sentence denotes An NF-kappa B binding site is an essential component of the element but alone is not sufficient to account for the activity or the specificity of the element.
S6 909-1045 Sentence denotes We have detected a specific nuclear protein complex that binds to the element and show that NF-kappa B1 (p50) is a part of this complex.
S7 1046-1397 Sentence denotes The EBV-encoded latent membrane protein 1 is capable of transactivating the isolated CD48 NF-kappa B site but not the intact element, suggesting that the latent membrane protein 1-driven activation of NF-kappa B/Rel must interact with other regulatory pathways to control expression of cellular genes as EBV drives resting B cells into the cell cycle.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 20-33 NP denotes the CD48 gene
C2 47-65 NP denotes a positive element
C3 66-70 NP denotes that
C4 144-172 NP denotes an essential NF-kappa B site
C5 212-235 NP denotes mature, resting B cells
C6 243-247 NP denotes them
C7 329-333 NP denotes CD48
C10 457-470 NP denotes the CD48 gene
C9 434-470 NP denotes an enhancer element in the CD48 gene
C11 471-476 NP denotes which
C8 434-578 NP denotes an enhancer element in the CD48 gene which reproducibly confers strong transcriptional activity only in EBV-positive B-lymphoblastoid cell lines
C12 580-591 NP denotes The element
C13 627-664 NP denotes established EBV-negative B-cell lines
C14 682-685 NP denotes EBV
C15 701-712 NP denotes these cells
C16 750-776 NP denotes An NF-kappa B binding site
C17 806-817 NP denotes the element
C18 896-907 NP denotes the element
C19 926-960 NP denotes a specific nuclear protein complex
C20 961-965 NP denotes that
C21 975-986 NP denotes the element
C22 1032-1044 NP denotes this complex
C23 1350-1353 NP denotes EBV
C24 1361-1376 NP denotes resting B cells
R1 C3 C2 coref-relat that,a positive element
R2 C6 C5 coref-pron them,"mature, resting B cells"
R3 C10 C7 coref-ident the CD48 gene,CD48
R4 C11 C9 coref-relat which,an enhancer element in the CD48 gene
R5 C12 C8 coref-ident The element,an enhancer element in the CD48 gene which reproducibly confers strong transcriptional activity only in EBV-positive B-lymphoblastoid cell lines
R6 C15 C13 coref-ident these cells,established EBV-negative B-cell lines
R7 C16 C4 coref-ident An NF-kappa B binding site,an essential NF-kappa B site
R8 C17 C12 coref-ident the element,The element
R9 C18 C17 coref-ident the element,the element
R10 C20 C19 coref-relat that,a specific nuclear protein complex
R11 C21 C18 coref-ident the element,the element
R12 C22 C19 coref-ident this complex,a specific nuclear protein complex
R13 C23 C14 coref-ident EBV,EBV
R14 C24 C5 coref-ident resting B cells,"mature, resting B cells"

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 24-33 DNA_domain_or_region denotes CD48 gene
T2 86-104 virus denotes Epstein-Barr virus
T3 157-167 protein_molecule denotes NF-kappa B
T4 174-192 virus denotes Epstein-Barr virus
T5 194-197 virus denotes EBV
T6 220-235 cell_type denotes resting B cells
T7 329-333 protein_molecule denotes CD48
T8 367-391 cell_type denotes normal activated B cells
T9 437-453 DNA_domain_or_region denotes enhancer element
T10 461-465 protein_molecule denotes CD48
T11 505-529 other_name denotes transcriptional activity
T12 538-541 virus denotes EBV
T13 639-642 virus denotes EBV
T14 682-685 virus denotes EBV
T15 724-748 cell_type denotes lymphoblastoid phenotype
T16 753-763 protein_molecule denotes NF-kappa B
T17 937-960 protein_complex denotes nuclear protein complex
T18 1001-1012 protein_subunit denotes NF-kappa B1
T19 1014-1017 protein_subunit denotes p50
T20 1050-1053 virus denotes EBV
T21 1131-1135 protein_molecule denotes CD48
T22 1136-1146 protein_molecule denotes NF-kappa B
T23 1164-1178 DNA_domain_or_region denotes intact element
T24 1200-1225 protein_molecule denotes latent membrane protein 1
T25 1247-1261 protein_molecule denotes NF-kappa B/Rel
T26 1350-1353 virus denotes EBV
T27 1361-1376 cell_type denotes resting B cells
T28 1386-1396 other_name denotes cell cycle