PubMed:7719937 JSON TXT

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Id	Subject	Object	Predicate	Lexical cue
T1	35-54	protein	denotes	human Stat proteins
T2	80-93	protein	denotes	interleukin-2
T3	101-109	protein	denotes	cytokine
T4	148-152	protein	denotes	IL-2
T5	202-206	protein	denotes	IL-2
T6	295-299	protein	denotes	IL-2
T7	361-374	cell_type	denotes	T lymphocytes
T8	463-467	protein	denotes	IL-2
T9	513-534	protein	denotes	transcription factors
T10	558-562	protein	denotes	IL-2
T11	564-598	cell_type	denotes	Human peripheral blood lymphocytes
T12	632-636	protein	denotes	IL-2
T13	714-747	cell_line	denotes	transformed human lymphocyte line
T14	756-758	cell_line	denotes	YT
T15	823-847	protein	denotes	IL-2-inducible component
T16	883-921	protein	denotes	prolactin-induced transcription factor
T17	942-968	cell_type	denotes	sheep mammary gland tissue
T18	1029-1035	protein	denotes	hStat5
T19	1076-1080	protein	denotes	IL-2

Id	Subject	Object	Predicate	Lexical cue
C1	80-93	NP	denotes	interleukin-2
C20	125-144	NP	denotes	the immune response
C2	148-152	NP	denotes	IL-2
C5	164-181	NP	denotes	T cell activation
C4	233-236	NP	denotes	its
C6	463-467	NP	denotes	IL-2
C7	558-562	NP	denotes	IL-2
C8	632-637	NP	denotes	IL-2-
C11	671-689	NP	denotes	Similar activities
C9	712-747	NP	denotes	a transformed human lymphocyte line
C10	756-758	NP	denotes	YT
C12	777-793	NP	denotes	these activities
C13	823-828	NP	denotes	IL-2-
C14	809-847	NP	denotes	the principal IL-2-inducible component
C15	1004-1016	NP	denotes	this protein
C16	990-1016	NP	denotes	activation of this protein
C18	1018-1035	NP	denotes	designated hStat5
C19	1076-1080	NP	denotes	IL-2
C21	1088-1107	NP	denotes	the immune response
R1	C2	C1	coref-ident	IL-2,interleukin-2
R2	C4	C5	coref-pron	its,T cell activation
R3	C6	C2	coref-ident	IL-2,IL-2
R4	C7	C6	coref-ident	IL-2,IL-2
R5	C8	C7	coref-ident	IL-2-,IL-2
R6	C10	C9	coref-ident	YT,a transformed human lymphocyte line
R7	C12	C11	coref-ident	these activities,Similar activities
R8	C13	C8	coref-ident	IL-2-,IL-2-
R9	C15	C14	coref-ident	this protein,the principal IL-2-inducible component
R10	C18	C16	coref-appos	designated hStat5,activation of this protein
R11	C19	C13	coref-ident	IL-2,IL-2-
R12	C21	C20	coref-ident	the immune response,the immune response

Id	Subject	Object	Predicate	Lexical cue
S1	0-94	Sentence	denotes	Identification and purification of human Stat proteins activated in response to interleukin-2.
S2	95-153	Sentence	denotes	A key cytokine induced during the immune response is IL-2.
S3	154-276	Sentence	denotes	Following T cell activation, the genes encoding IL-2 and the various chains of its receptor are transcriptionally induced.
S4	277-375	Sentence	denotes	In turn, secreted IL-2 serves to stimulate the proliferation and differentiation of T lymphocytes.
S5	376-468	Sentence	denotes	Several recent studies have implicated Jak kinases in the signaling pathway induced by IL-2.
S6	469-563	Sentence	denotes	Following this lead, we set out to identify transcription factors induced in response to IL-2.
S7	564-670	Sentence	denotes	Human peripheral blood lymphocytes were observed to contain several IL-2-inducible DNA binding activities.
S8	671-759	Sentence	denotes	Similar activities were also observed in a transformed human lymphocyte line, termed YT.
S9	760-969	Sentence	denotes	We have purified these activities and found that the principal IL-2-inducible component bears significant relatedness to a prolactin-induced transcription factor first identified in sheep mammary gland tissue.
S10	970-1108	Sentence	denotes	We hypothesize that activation of this protein, designated hStat5, helps govern the biological effects of IL-2 during the immune response.

Id	Subject	Object	Predicate	Lexical cue
T1	35-54	protein_family_or_group	denotes	human Stat proteins
T2	80-93	protein_molecule	denotes	interleukin-2
T3	101-109	protein_family_or_group	denotes	cytokine
T4	129-144	other_name	denotes	immune response
T5	148-152	protein_molecule	denotes	IL-2
T6	164-181	other_name	denotes	T cell activation
T7	202-206	protein_molecule	denotes	IL-2
T8	295-299	protein_molecule	denotes	IL-2
T9	361-374	cell_type	denotes	T lymphocytes
T10	434-451	other_name	denotes	signaling pathway
T11	463-467	protein_molecule	denotes	IL-2
T12	513-534	protein_family_or_group	denotes	transcription factors
T13	558-562	protein_molecule	denotes	IL-2
T14	564-598	cell_type	denotes	Human peripheral blood lymphocytes
T15	632-636	protein_molecule	denotes	IL-2
T16	714-747	cell_line	denotes	transformed human lymphocyte line
T17	756-758	cell_line	denotes	YT
T18	823-827	protein_molecule	denotes	IL-2
T19	883-921	protein_molecule	denotes	prolactin-induced transcription factor
T20	942-968	cell_type	denotes	sheep mammary gland tissue
T21	1029-1035	protein_molecule	denotes	hStat5
T22	1076-1080	protein_molecule	denotes	IL-2
T23	1092-1107	other_name	denotes	immune response