PubMed:7678256 / 1712-2037 JSONTXT

{"project":"GlyCosmos6-Glycan-Motif-Image","denotations":[{"id":"T21","span":{"begin":56,"end":59},"obj":"Glycan_Motif"},{"id":"T23","span":{"begin":137,"end":140},"obj":"Glycan_Motif"}],"attributes":[{"id":"A21","pred":"image","subj":"T21","obj":"https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G48558GR"},{"id":"A22","pred":"image","subj":"T21","obj":"https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G46613JI"},{"id":"A23","pred":"image","subj":"T23","obj":"https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G48558GR"},{"id":"A24","pred":"image","subj":"T23","obj":"https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G46613JI"}],"text":"These observations demonstrate that the first action of GM1 is to mask epitopes located within the first two NH2-terminal domains; then, GM1 triggers protein kinase C-independent signals which cause p56lck dissociation from CD4 and the delivery of the molecule to an intracellular compartment where it is eventually degraded."}

{"project":"Glycosmos6-GlycoEpitope","denotations":[{"id":"T11","span":{"begin":56,"end":59},"obj":"http://www.glycoepitope.jp/epitopes/EP0050"},{"id":"T12","span":{"begin":137,"end":140},"obj":"http://www.glycoepitope.jp/epitopes/EP0050"}],"text":"These observations demonstrate that the first action of GM1 is to mask epitopes located within the first two NH2-terminal domains; then, GM1 triggers protein kinase C-independent signals which cause p56lck dissociation from CD4 and the delivery of the molecule to an intracellular compartment where it is eventually degraded."}

{"project":"sentences","denotations":[{"id":"T9","span":{"begin":0,"end":325},"obj":"Sentence"},{"id":"T9","span":{"begin":0,"end":325},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"These observations demonstrate that the first action of GM1 is to mask epitopes located within the first two NH2-terminal domains; then, GM1 triggers protein kinase C-independent signals which cause p56lck dissociation from CD4 and the delivery of the molecule to an intracellular compartment where it is eventually degraded."}

{"project":"GlyCosmos6-Glycan-Motif-Structure","denotations":[{"id":"T21","span":{"begin":56,"end":59},"obj":"https://glytoucan.org/Structures/Glycans/G46613JI"},{"id":"T22","span":{"begin":56,"end":59},"obj":"https://glytoucan.org/Structures/Glycans/G48558GR"},{"id":"T23","span":{"begin":137,"end":140},"obj":"https://glytoucan.org/Structures/Glycans/G46613JI"},{"id":"T24","span":{"begin":137,"end":140},"obj":"https://glytoucan.org/Structures/Glycans/G48558GR"}],"text":"These observations demonstrate that the first action of GM1 is to mask epitopes located within the first two NH2-terminal domains; then, GM1 triggers protein kinase C-independent signals which cause p56lck dissociation from CD4 and the delivery of the molecule to an intracellular compartment where it is eventually degraded."}

{"project":"Glycan-GlyCosmos","denotations":[{"id":"T11","span":{"begin":56,"end":59},"obj":"Glycan"},{"id":"T12","span":{"begin":137,"end":140},"obj":"Glycan"}],"attributes":[{"id":"A11","pred":"glycosmos_id","subj":"T11","obj":"https://glycosmos.org/glycans/show/G48558GR"},{"id":"A23","pred":"image","subj":"T11","obj":"https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR"},{"id":"A12","pred":"glycosmos_id","subj":"T12","obj":"https://glycosmos.org/glycans/show/G48558GR"},{"id":"A24","pred":"image","subj":"T12","obj":"https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR"}],"text":"These observations demonstrate that the first action of GM1 is to mask epitopes located within the first two NH2-terminal domains; then, GM1 triggers protein kinase C-independent signals which cause p56lck dissociation from CD4 and the delivery of the molecule to an intracellular compartment where it is eventually degraded."}

{"project":"GlyCosmos-GlycoEpitope","denotations":[{"id":"T11","span":{"begin":56,"end":59},"obj":"http://purl.jp/bio/12/glyco/glycan#Glycan_epitope"},{"id":"T12","span":{"begin":137,"end":140},"obj":"http://purl.jp/bio/12/glyco/glycan#Glycan_epitope"}],"attributes":[{"id":"A11","pred":"glycoepitope_id","subj":"T11","obj":"http://www.glycoepitope.jp/epitopes/EP0050"},{"id":"A12","pred":"glycoepitope_id","subj":"T12","obj":"http://www.glycoepitope.jp/epitopes/EP0050"}],"text":"These observations demonstrate that the first action of GM1 is to mask epitopes located within the first two NH2-terminal domains; then, GM1 triggers protein kinase C-independent signals which cause p56lck dissociation from CD4 and the delivery of the molecule to an intracellular compartment where it is eventually degraded."}

{"project":"GlyCosmos15-UBERON","denotations":[{"id":"T4","span":{"begin":267,"end":280},"obj":"Body_part"}],"attributes":[{"id":"A4","pred":"uberon_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/GO_0005622"}],"text":"These observations demonstrate that the first action of GM1 is to mask epitopes located within the first two NH2-terminal domains; then, GM1 triggers protein kinase C-independent signals which cause p56lck dissociation from CD4 and the delivery of the molecule to an intracellular compartment where it is eventually degraded."}

{"project":"sentences","denotations":[{"id":"T9","span":{"begin":0,"end":325},"obj":"Sentence"},{"id":"T9","span":{"begin":0,"end":325},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"These observations demonstrate that the first action of GM1 is to mask epitopes located within the first two NH2-terminal domains; then, GM1 triggers protein kinase C-independent signals which cause p56lck dissociation from CD4 and the delivery of the molecule to an intracellular compartment where it is eventually degraded."}

{"project":"GlyCosmos15-Sentences","blocks":[{"id":"T9","span":{"begin":0,"end":325},"obj":"Sentence"}],"text":"These observations demonstrate that the first action of GM1 is to mask epitopes located within the first two NH2-terminal domains; then, GM1 triggers protein kinase C-independent signals which cause p56lck dissociation from CD4 and the delivery of the molecule to an intracellular compartment where it is eventually degraded."}

{"project":"GlyCosmos15-Glycan","denotations":[{"id":"T11","span":{"begin":56,"end":59},"obj":"Glycan"},{"id":"T12","span":{"begin":137,"end":140},"obj":"Glycan"}],"attributes":[{"id":"A11","pred":"glycosmos_id","subj":"T11","obj":"https://glycosmos.org/glycans/show/G48558GR"},{"id":"A23","pred":"image","subj":"T11","obj":"https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR"},{"id":"A12","pred":"glycosmos_id","subj":"T12","obj":"https://glycosmos.org/glycans/show/G48558GR"},{"id":"A24","pred":"image","subj":"T12","obj":"https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR"}],"text":"These observations demonstrate that the first action of GM1 is to mask epitopes located within the first two NH2-terminal domains; then, GM1 triggers protein kinase C-independent signals which cause p56lck dissociation from CD4 and the delivery of the molecule to an intracellular compartment where it is eventually degraded."}

{"project":"GlyCosmos15-GlycoEpitope","denotations":[{"id":"T11","span":{"begin":56,"end":59},"obj":"http://purl.jp/bio/12/glyco/glycan#Glycan_epitope"},{"id":"T12","span":{"begin":137,"end":140},"obj":"http://purl.jp/bio/12/glyco/glycan#Glycan_epitope"}],"attributes":[{"id":"A11","pred":"glycoepitope_id","subj":"T11","obj":"http://www.glycoepitope.jp/epitopes/EP0050"},{"id":"A12","pred":"glycoepitope_id","subj":"T12","obj":"http://www.glycoepitope.jp/epitopes/EP0050"}],"text":"These observations demonstrate that the first action of GM1 is to mask epitopes located within the first two NH2-terminal domains; then, GM1 triggers protein kinase C-independent signals which cause p56lck dissociation from CD4 and the delivery of the molecule to an intracellular compartment where it is eventually degraded."}

{"project":"Anatomy-UBERON","denotations":[{"id":"T4","span":{"begin":267,"end":280},"obj":"Body_part"}],"attributes":[{"id":"A4","pred":"uberon_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/GO_0005622"}],"text":"These observations demonstrate that the first action of GM1 is to mask epitopes located within the first two NH2-terminal domains; then, GM1 triggers protein kinase C-independent signals which cause p56lck dissociation from CD4 and the delivery of the molecule to an intracellular compartment where it is eventually degraded."}