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PubMed:7605997 JSONTXT

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DisGeNET

Id Subject Object Predicate Lexical cue
T0 23-27 gene:6886 denotes TAL1
T1 70-105 disease:C1961099 denotes T-cell acute lymphoblastic leukemia
T2 255-259 gene:6886 denotes TAL1
T3 169-204 disease:C1961099 denotes T-cell acute lymphoblastic leukemia
T4 487-491 gene:6886 denotes TAL1
T5 520-525 disease:C1961099 denotes T-ALL
T6 556-560 gene:6886 denotes TAL1
T7 618-623 disease:C1961099 denotes T-ALL
T8 813-817 gene:6886 denotes TAL1
T9 843-848 disease:C1961099 denotes T-ALL
T10 760-764 gene:6886 denotes TAL1
T11 843-848 disease:C1961099 denotes T-ALL
R1 T0 T1 associated_with TAL1,T-cell acute lymphoblastic leukemia
R2 T2 T3 associated_with TAL1,T-cell acute lymphoblastic leukemia
R3 T4 T5 associated_with TAL1,T-ALL
R4 T6 T7 associated_with TAL1,T-ALL
R5 T8 T9 associated_with TAL1,T-ALL
R6 T10 T11 associated_with TAL1,T-ALL

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 23-32 DNA denotes TAL1 gene
T2 255-264 DNA denotes TAL1 gene
T3 275-279 protein denotes TAL1
T4 316-334 cell_type denotes normal lymphocytes
T5 336-354 protein denotes TAL1 gene products
T6 379-393 cell_type denotes leukemic cells
T7 408-430 DNA denotes rearranged TAL1 allele
T8 487-491 protein denotes TAL1
T9 556-560 protein denotes TAL1
T10 581-595 cell_type denotes leukemic cells
T11 672-681 DNA denotes TAL1 gene
T12 760-764 protein denotes TAL1
T13 813-817 protein denotes TAL1
T14 835-854 cell_type denotes primary T-ALL cells
T15 882-886 protein denotes TAL1
T16 907-921 cell_type denotes leukemic cells
T17 957-966 DNA denotes TAL1 gene
T18 989-1003 cell_type denotes leukemic cells
T19 1035-1039 protein denotes TAL1
T20 1056-1060 protein denotes TAL1
T21 1174-1178 protein denotes TAL1
T22 1246-1277 DNA denotes cis-acting regulatory sequences
T23 1305-1323 DNA denotes single TAL1 allele
T24 1373-1377 protein denotes TAL1
T25 1422-1434 DNA denotes TAL1 alleles

DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
7605997-0#23#27#gene6886 23-27 gene6886 denotes TAL1
7605997-0#70#105#diseaseC1961099 70-105 diseaseC1961099 denotes T-cell acute lymphoblastic leukemia
23#27#gene688670#105#diseaseC1961099 7605997-0#23#27#gene6886 7605997-0#70#105#diseaseC1961099 associated_with TAL1,T-cell acute lymphoblastic leukemia

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-106 Sentence denotes Does activation of the TAL1 gene occur in a majority of patients with T-cell acute lymphoblastic leukemia?
S2 107-140 Sentence denotes A pediatric oncology group study.
S3 141-265 Sentence denotes Almost 25% of patients with T-cell acute lymphoblastic leukemia (T-ALL) have tumor-specific rearrangements of the TAL1 gene.
S4 266-431 Sentence denotes Although TAL1 expression has not been observed in normal lymphocytes, TAL1 gene products are readily detected in leukemic cells that harbor a rearranged TAL1 allele.
S5 432-526 Sentence denotes Hence, it has been proposed that ectopic expression of TAL1 promotes the development of T-ALL.
S6 527-693 Sentence denotes In this report, we show that TAL1 is expressed in the leukemic cells of most patients with T-ALL, including many that do not display an apparent TAL1 gene alteration.
S7 694-855 Sentence denotes A polymorphic dinucleotide repeat in the transcribed sequences of TAL1 was used to determine the allele specificity of TAL1 transcription in primary T-ALL cells.
S8 856-981 Sentence denotes Monoallelic expression of TAL1 was observed in the leukemic cells of all patients (8 of 8) bearing a TAL1 gene rearrangement.
S9 982-1167 Sentence denotes In the leukemic cells of patients without detectable TAL1 rearrangements, TAL1 transcription occurred in either a monoallelic (3 of 7 patients) or a biallelic (4 of 7 patients) fashion.
S10 1168-1436 Sentence denotes Thus, TAL1 activation in these patients may result from subtle alterations in cis-acting regulatory sequences (affecting expression of a single TAL1 allele) or changes in trans-acting factors that control TAL1 transcription (affecting expression of both TAL1 alleles).

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 19-32 NP denotes the TAL1 gene
C4 70-105 NP denotes T-cell acute lymphoblastic leukemia
C3 56-105 NP denotes patients with T-cell acute lymphoblastic leukemia
C2 42-105 NP denotes a majority of patients with T-cell acute lymphoblastic leukemia
C6 169-212 NP denotes T-cell acute lymphoblastic leukemia (T-ALL)
C5 155-212 NP denotes patients with T-cell acute lymphoblastic leukemia (T-ALL)
C7 251-264 NP denotes the TAL1 gene
C8 379-393 NP denotes leukemic cells
C9 394-398 NP denotes that
C10 487-491 NP denotes TAL1
C11 520-525 NP denotes T-ALL
C12 556-560 NP denotes TAL1
C14 618-623 NP denotes T-ALL
C13 599-623 NP denotes most patients with T-ALL
C15 635-639 NP denotes many
C16 640-644 NP denotes that
C17 760-764 NP denotes TAL1
C18 813-831 NP denotes TAL1 transcription
C19 882-886 NP denotes TAL1
C20 1007-1054 NP denotes patients without detectable TAL1 rearrangements
C21 1056-1074 NP denotes TAL1 transcription
C22 1193-1207 NP denotes these patients
C23 1339-1359 NP denotes trans-acting factors
C24 1360-1364 NP denotes that
C25 1373-1391 NP denotes TAL1 transcription
R1 C6 C4 coref-ident T-cell acute lymphoblastic leukemia (T-ALL),T-cell acute lymphoblastic leukemia
R2 C5 C3 coref-ident patients with T-cell acute lymphoblastic leukemia (T-ALL),patients with T-cell acute lymphoblastic leukemia
R3 C7 C1 coref-ident the TAL1 gene,the TAL1 gene
R4 C9 C8 coref-relat that,leukemic cells
R5 C10 C7 coref-ident TAL1,the TAL1 gene
R6 C11 C6 coref-ident T-ALL,T-cell acute lymphoblastic leukemia (T-ALL)
R7 C12 C10 coref-ident TAL1,TAL1
R8 C14 C11 coref-ident T-ALL,T-ALL
R9 C13 C2 coref-ident most patients with T-ALL,a majority of patients with T-cell acute lymphoblastic leukemia
R10 C16 C15 coref-relat that,many
R11 C17 C12 coref-ident TAL1,TAL1
R12 C19 C17 coref-ident TAL1,TAL1
R13 C21 C18 coref-ident TAL1 transcription,TAL1 transcription
R14 C22 C20 coref-ident these patients,patients without detectable TAL1 rearrangements
R15 C24 C23 coref-relat that,trans-acting factors
R16 C25 C21 coref-ident TAL1 transcription,TAL1 transcription

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 23-32 DNA_domain_or_region denotes TAL1 gene
T2 56-64 multi_cell denotes patients
T3 70-105 other_name denotes T-cell acute lymphoblastic leukemia
T4 109-139 other_name denotes pediatric oncology group study
T5 155-163 multi_cell denotes patients
T6 169-204 other_name denotes T-cell acute lymphoblastic leukemia
T7 206-211 other_name denotes T-ALL
T8 218-247 other_name denotes tumor-specific rearrangements
T9 255-264 DNA_domain_or_region denotes TAL1 gene
T10 275-279 protein_molecule denotes TAL1
T11 316-334 cell_type denotes normal lymphocytes
T12 336-345 DNA_domain_or_region denotes TAL1 gene
T13 379-393 cell_type denotes leukemic cells
T14 408-430 DNA_family_or_group denotes rearranged TAL1 allele
T15 465-483 other_name denotes ectopic expression
T16 487-491 protein_molecule denotes TAL1
T17 520-525 other_name denotes T-ALL
T18 556-560 protein_molecule denotes TAL1
T19 581-595 cell_type denotes leukemic cells
T20 604-612 multi_cell denotes patients
T21 618-623 other_name denotes T-ALL
T22 672-676 protein_molecule denotes TAL1
T23 760-764 protein_molecule denotes TAL1
T24 791-809 other_name denotes allele specificity
T25 813-817 protein_molecule denotes TAL1
T26 835-842 cell_type denotes primary
T27 843-848 other_name denotes T-ALL
T28 856-878 other_name denotes Monoallelic expression
T29 882-886 protein_molecule denotes TAL1
T30 907-921 cell_type denotes leukemic cells
T31 929-937 multi_cell denotes patients
T32 957-961 protein_molecule denotes TAL1
T33 989-1003 cell_type denotes leukemic cells
T34 1007-1015 multi_cell denotes patients
T35 1035-1039 protein_molecule denotes TAL1
T36 1056-1060 protein_molecule denotes TAL1
T37 1116-1124 multi_cell denotes patients
T38 1149-1157 multi_cell denotes patients
T39 1174-1178 protein_molecule denotes TAL1
T40 1199-1207 multi_cell denotes patients
T41 1246-1277 DNA_family_or_group denotes cis-acting regulatory sequences
T42 1305-1311 DNA_domain_or_region denotes single
T43 1312-1316 protein_molecule denotes TAL1
T44 1373-1377 protein_molecule denotes TAL1
T45 1422-1426 protein_molecule denotes TAL1