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PubMed:7604283 JSONTXT

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jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 25-28 protein denotes Jak
T2 28-33 protein denotes -STAT
T3 45-52 cell_type denotes T cells
T4 249-289 cell_type denotes HTLV-I-infected peripheral blood T cells
T5 318-331 protein denotes interleukin-2
T6 333-337 protein denotes IL-2
T7 410-414 protein denotes IL-2
T8 440-451 protein denotes Jak kinases
T9 452-456 protein denotes Jak1
T10 461-465 protein denotes Jak3
T11 509-531 protein denotes transcription proteins
T12 532-537 protein denotes Stat3
T13 542-547 protein denotes Stat5
T14 565-579 cell_type denotes normal T cells
T15 595-599 protein denotes IL-2
T16 656-680 cell_line denotes HTLV-I-transformed cells
T17 685-723 cell_line denotes HTLV-I-infected cord blood lymphocytes
T18 745-749 protein denotes IL-2
T19 763-767 protein denotes IL-2
T20 849-852 protein denotes Jak
T21 852-857 protein denotes -STAT

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-77 Sentence denotes Constitutively activated Jak-STAT pathway in T cells transformed with HTLV-I.
S2 78-248 Sentence denotes Human T cell lymphotropic virus I (HTLV-I) is the etiological agent for adult T cell leukemia and tropical spastic paraparesis (also termed HTLV-I-associated myelopathy).
S3 249-427 Sentence denotes HTLV-I-infected peripheral blood T cells exhibit an initial phase of interleukin-2 (IL-2)-dependent growth; over time, by an unknown mechanism, the cells become IL-2-independent.
S4 428-681 Sentence denotes Whereas the Jak kinases Jak1 and Jak3 and the signal transducer and activator of transcription proteins Stat3 and Stat5 are activated in normal T cells in response to IL-2, this signaling pathway was constitutively activated in HTLV-I-transformed cells.
S5 682-954 Sentence denotes In HTLV-I-infected cord blood lymphocytes, the transition from IL-2-dependent to IL-2-independent growth correlated with the acquisition of a constitutively activated Jak-STAT pathway, which suggests that this pathway participates in HTLV-I-mediated T cell transformation.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 70-76 NP denotes HTLV-I
C9 45-76 NP denotes T cells transformed with HTLV-I
C2 78-120 NP denotes Human T cell lymphotropic virus I (HTLV-I)
C3 124-247 NP denotes the etiological agent for adult T cell leukemia and tropical spastic paraparesis (also termed HTLV-I-associated myelopathy)
C4 249-256 NP denotes HTLV-I-
C5 318-339 NP denotes interleukin-2 (IL-2)-
C6 410-415 NP denotes IL-2-
C7 595-599 NP denotes IL-2
C8 656-663 NP denotes HTLV-I-
C10 656-680 NP denotes HTLV-I-transformed cells
C11 685-692 NP denotes HTLV-I-
C12 745-750 NP denotes IL-2-
C13 763-768 NP denotes IL-2-
C14 822-865 NP denotes a constitutively activated Jak-STAT pathway
C18 803-865 NP denotes the acquisition of a constitutively activated Jak-STAT pathway
C19 867-872 NP denotes which
C15 887-899 NP denotes this pathway
C16 916-923 NP denotes HTLV-I-
R1 C2 C1 coref-ident Human T cell lymphotropic virus I (HTLV-I),HTLV-I
R2 C3 C2 coref-ident the etiological agent for adult T cell leukemia and tropical spastic paraparesis (also termed HTLV-I-associated myelopathy),Human T cell lymphotropic virus I (HTLV-I)
R3 C4 C2 coref-ident HTLV-I-,Human T cell lymphotropic virus I (HTLV-I)
R4 C6 C5 coref-ident IL-2-,interleukin-2 (IL-2)-
R5 C7 C6 coref-ident IL-2,IL-2-
R6 C8 C4 coref-ident HTLV-I-,HTLV-I-
R7 C10 C9 coref-ident HTLV-I-transformed cells,T cells transformed with HTLV-I
R8 C11 C8 coref-ident HTLV-I-,HTLV-I-
R9 C12 C7 coref-ident IL-2-,IL-2
R10 C13 C12 coref-ident IL-2-,IL-2-
R11 C19 C18 coref-relat which,the acquisition of a constitutively activated Jak-STAT pathway
R12 C15 C14 coref-ident this pathway,a constitutively activated Jak-STAT pathway
R13 C16 C11 coref-ident HTLV-I-,HTLV-I-

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 25-28 protein_family_or_group denotes Jak
T2 28-33 protein_family_or_group denotes -STAT
T3 45-52 cell_type denotes T cells
T4 70-76 virus denotes HTLV-I
T5 78-111 virus denotes Human T cell lymphotropic virus I
T6 113-119 virus denotes HTLV-I
T7 128-145 other_name denotes etiological agent
T8 150-171 other_name denotes adult T cell leukemia
T9 176-204 other_name denotes tropical spastic paraparesis
T10 218-224 virus denotes HTLV-I
T11 249-255 virus denotes HTLV-I
T12 282-289 cell_type denotes T cells
T13 318-331 protein_molecule denotes interleukin-2
T14 333-337 protein_molecule denotes IL-2
T15 410-414 protein_molecule denotes IL-2
T16 440-451 protein_family_or_group denotes Jak kinases
T17 452-456 protein_molecule denotes Jak1
T18 461-465 protein_molecule denotes Jak3
T19 509-531 protein_family_or_group denotes transcription proteins
T20 532-537 protein_molecule denotes Stat3
T21 542-547 protein_molecule denotes Stat5
T22 565-571 cell_type denotes normal
T23 572-579 cell_type denotes T cells
T24 595-599 protein_molecule denotes IL-2
T25 656-662 virus denotes HTLV-I
T26 685-691 virus denotes HTLV-I
T27 745-749 protein_molecule denotes IL-2
T28 763-767 protein_molecule denotes IL-2
T29 849-852 protein_family_or_group denotes Jak
T30 852-857 protein_family_or_group denotes -STAT
T31 916-922 virus denotes HTLV-I