PubMed:7578250 JSONTXT

{"project":"jnlpba-st-training","denotations":[{"id":"T1","span":{"begin":10,"end":14},"obj":"DNA"},{"id":"T2","span":{"begin":26,"end":36},"obj":"cell_type"},{"id":"T3","span":{"begin":92,"end":102},"obj":"DNA"},{"id":"T4","span":{"begin":104,"end":108},"obj":"DNA"},{"id":"T5","span":{"begin":130,"end":182},"obj":"DNA"},{"id":"T6","span":{"begin":188,"end":192},"obj":"DNA"},{"id":"T7","span":{"begin":212,"end":216},"obj":"RNA"},{"id":"T8","span":{"begin":260,"end":274},"obj":"protein"},{"id":"T9","span":{"begin":334,"end":342},"obj":"DNA"},{"id":"T10","span":{"begin":446,"end":450},"obj":"DNA"},{"id":"T11","span":{"begin":516,"end":542},"obj":"protein"},{"id":"T12","span":{"begin":560,"end":571},"obj":"protein"},{"id":"T13","span":{"begin":602,"end":626},"obj":"protein"},{"id":"T14","span":{"begin":664,"end":668},"obj":"DNA"},{"id":"T15","span":{"begin":716,"end":727},"obj":"protein"},{"id":"T16","span":{"begin":769,"end":773},"obj":"DNA"},{"id":"T17","span":{"begin":783,"end":805},"obj":"DNA"},{"id":"T18","span":{"begin":828,"end":846},"obj":"cell_line"},{"id":"T19","span":{"begin":952,"end":968},"obj":"protein"},{"id":"T20","span":{"begin":982,"end":999},"obj":"protein"},{"id":"T21","span":{"begin":1003,"end":1014},"obj":"cell_type"}],"text":"Cloning a cDNA from human NK/T cells which codes for a protein with high proline content.\nA cDNA clone, B4-2, was isolated from a natural killer (NK) minus T cell subtractive library. The B4-2 clone coded for an mRNA of 2061 bp in length. It encodes a deduced 327 aa protein with a calculated molecular mass of 35.2 kDa. Searching of B4-2 DNA and protein sequences against various databases revealed no high homology to other sequences. However, B4-2 has an unusually high proline content (13%), contains a putative nuclear targeting sequence, and has several SPXX motifs which are frequently found in gene regulatory proteins. One of the stretches of prolines in B4-2 closely resembles the ligand for proteins with SH3 domains. Northern hybridization data showed that B4-2 is not a lymphoid specific gene and is expressed in a hepatoma cell line and also weakly transcribed or absent in a variety of other cells. A polyclonal antiserum raised against recombinant B4-2 recognizes a 32-34 kDa protein in lymphocytes."}

{"project":"genia-medco-coref","denotations":[{"id":"C1","span":{"begin":8,"end":36},"obj":"NP"},{"id":"C2","span":{"begin":37,"end":42},"obj":"NP"},{"id":"C3","span":{"begin":53,"end":88},"obj":"NP"},{"id":"C4","span":{"begin":90,"end":102},"obj":"NP"},{"id":"C5","span":{"begin":104,"end":108},"obj":"NP"},{"id":"C6","span":{"begin":184,"end":198},"obj":"NP"},{"id":"C7","span":{"begin":239,"end":241},"obj":"NP"},{"id":"C8","span":{"begin":250,"end":319},"obj":"NP"},{"id":"C9","span":{"begin":446,"end":450},"obj":"NP"},{"id":"C10","span":{"begin":552,"end":571},"obj":"NP"},{"id":"C11","span":{"begin":572,"end":577},"obj":"NP"},{"id":"C12","span":{"begin":664,"end":668},"obj":"NP"},{"id":"C13","span":{"begin":769,"end":773},"obj":"NP"}],"relations":[{"id":"R1","pred":"coref-relat","subj":"C2","obj":"C1"},{"id":"R2","pred":"coref-appos","subj":"C5","obj":"C4"},{"id":"R3","pred":"coref-ident","subj":"C6","obj":"C4"},{"id":"R4","pred":"coref-pron","subj":"C7","obj":"C6"},{"id":"R5","pred":"coref-ident","subj":"C8","obj":"C3"},{"id":"R6","pred":"coref-ident","subj":"C9","obj":"C6"},{"id":"R7","pred":"coref-relat","subj":"C11","obj":"C10"},{"id":"R8","pred":"coref-ident","subj":"C12","obj":"C9"},{"id":"R9","pred":"coref-ident","subj":"C13","obj":"C12"}],"text":"Cloning a cDNA from human NK/T cells which codes for a protein with high proline content.\nA cDNA clone, B4-2, was isolated from a natural killer (NK) minus T cell subtractive library. The B4-2 clone coded for an mRNA of 2061 bp in length. It encodes a deduced 327 aa protein with a calculated molecular mass of 35.2 kDa. Searching of B4-2 DNA and protein sequences against various databases revealed no high homology to other sequences. However, B4-2 has an unusually high proline content (13%), contains a putative nuclear targeting sequence, and has several SPXX motifs which are frequently found in gene regulatory proteins. One of the stretches of prolines in B4-2 closely resembles the ligand for proteins with SH3 domains. Northern hybridization data showed that B4-2 is not a lymphoid specific gene and is expressed in a hepatoma cell line and also weakly transcribed or absent in a variety of other cells. A polyclonal antiserum raised against recombinant B4-2 recognizes a 32-34 kDa protein in lymphocytes."}

{"project":"pubmed-sentences-benchmark","denotations":[{"id":"S1","span":{"begin":0,"end":89},"obj":"Sentence"},{"id":"S2","span":{"begin":90,"end":183},"obj":"Sentence"},{"id":"S3","span":{"begin":184,"end":238},"obj":"Sentence"},{"id":"S4","span":{"begin":239,"end":320},"obj":"Sentence"},{"id":"S5","span":{"begin":321,"end":436},"obj":"Sentence"},{"id":"S6","span":{"begin":437,"end":627},"obj":"Sentence"},{"id":"S7","span":{"begin":628,"end":728},"obj":"Sentence"},{"id":"S8","span":{"begin":729,"end":913},"obj":"Sentence"},{"id":"S9","span":{"begin":914,"end":1015},"obj":"Sentence"}],"text":"Cloning a cDNA from human NK/T cells which codes for a protein with high proline content.\nA cDNA clone, B4-2, was isolated from a natural killer (NK) minus T cell subtractive library. The B4-2 clone coded for an mRNA of 2061 bp in length. It encodes a deduced 327 aa protein with a calculated molecular mass of 35.2 kDa. Searching of B4-2 DNA and protein sequences against various databases revealed no high homology to other sequences. However, B4-2 has an unusually high proline content (13%), contains a putative nuclear targeting sequence, and has several SPXX motifs which are frequently found in gene regulatory proteins. One of the stretches of prolines in B4-2 closely resembles the ligand for proteins with SH3 domains. Northern hybridization data showed that B4-2 is not a lymphoid specific gene and is expressed in a hepatoma cell line and also weakly transcribed or absent in a variety of other cells. A polyclonal antiserum raised against recombinant B4-2 recognizes a 32-34 kDa protein in lymphocytes."}

{"project":"GENIAcorpus","denotations":[{"id":"T1","span":{"begin":10,"end":14},"obj":"DNA_family_or_group"},{"id":"T2","span":{"begin":26,"end":29},"obj":"cell_type"},{"id":"T3","span":{"begin":29,"end":36},"obj":"cell_type"},{"id":"T4","span":{"begin":73,"end":80},"obj":"amino_acid_monomer"},{"id":"T5","span":{"begin":92,"end":102},"obj":"DNA_family_or_group"},{"id":"T6","span":{"begin":104,"end":108},"obj":"DNA_molecule"},{"id":"T7","span":{"begin":130,"end":182},"obj":"DNA_family_or_group"},{"id":"T8","span":{"begin":188,"end":192},"obj":"DNA_molecule"},{"id":"T9","span":{"begin":212,"end":216},"obj":"RNA_family_or_group"},{"id":"T10","span":{"begin":260,"end":274},"obj":"protein_molecule"},{"id":"T11","span":{"begin":293,"end":307},"obj":"other_name"},{"id":"T12","span":{"begin":334,"end":338},"obj":"DNA_molecule"},{"id":"T13","span":{"begin":347,"end":364},"obj":"other_name"},{"id":"T14","span":{"begin":446,"end":450},"obj":"DNA_molecule"},{"id":"T15","span":{"begin":473,"end":480},"obj":"amino_acid_monomer"},{"id":"T16","span":{"begin":516,"end":542},"obj":"protein_domain_or_region"},{"id":"T17","span":{"begin":602,"end":626},"obj":"protein_family_or_group"},{"id":"T18","span":{"begin":652,"end":660},"obj":"amino_acid_monomer"},{"id":"T19","span":{"begin":664,"end":668},"obj":"DNA_molecule"},{"id":"T20","span":{"begin":716,"end":727},"obj":"protein_domain_or_region"},{"id":"T21","span":{"begin":769,"end":773},"obj":"DNA_molecule"},{"id":"T22","span":{"begin":783,"end":805},"obj":"DNA_family_or_group"},{"id":"T23","span":{"begin":828,"end":846},"obj":"cell_line"},{"id":"T24","span":{"begin":916,"end":936},"obj":"other_organic_compound"},{"id":"T25","span":{"begin":952,"end":963},"obj":"protein_molecule"},{"id":"T26","span":{"begin":964,"end":968},"obj":"DNA_molecule"},{"id":"T27","span":{"begin":982,"end":999},"obj":"protein_molecule"},{"id":"T28","span":{"begin":1003,"end":1014},"obj":"cell_type"}],"text":"Cloning a cDNA from human NK/T cells which codes for a protein with high proline content.\nA cDNA clone, B4-2, was isolated from a natural killer (NK) minus T cell subtractive library. The B4-2 clone coded for an mRNA of 2061 bp in length. It encodes a deduced 327 aa protein with a calculated molecular mass of 35.2 kDa. Searching of B4-2 DNA and protein sequences against various databases revealed no high homology to other sequences. However, B4-2 has an unusually high proline content (13%), contains a putative nuclear targeting sequence, and has several SPXX motifs which are frequently found in gene regulatory proteins. One of the stretches of prolines in B4-2 closely resembles the ligand for proteins with SH3 domains. Northern hybridization data showed that B4-2 is not a lymphoid specific gene and is expressed in a hepatoma cell line and also weakly transcribed or absent in a variety of other cells. A polyclonal antiserum raised against recombinant B4-2 recognizes a 32-34 kDa protein in lymphocytes."}

{"project":"mondo_disease","denotations":[{"id":"T1","span":{"begin":828,"end":836},"obj":"Disease"}],"attributes":[{"id":"A1","pred":"mondo_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/MONDO_0007256"}],"text":"Cloning a cDNA from human NK/T cells which codes for a protein with high proline content.\nA cDNA clone, B4-2, was isolated from a natural killer (NK) minus T cell subtractive library. The B4-2 clone coded for an mRNA of 2061 bp in length. It encodes a deduced 327 aa protein with a calculated molecular mass of 35.2 kDa. Searching of B4-2 DNA and protein sequences against various databases revealed no high homology to other sequences. However, B4-2 has an unusually high proline content (13%), contains a putative nuclear targeting sequence, and has several SPXX motifs which are frequently found in gene regulatory proteins. One of the stretches of prolines in B4-2 closely resembles the ligand for proteins with SH3 domains. Northern hybridization data showed that B4-2 is not a lymphoid specific gene and is expressed in a hepatoma cell line and also weakly transcribed or absent in a variety of other cells. A polyclonal antiserum raised against recombinant B4-2 recognizes a 32-34 kDa protein in lymphocytes."}

{"project":"NCBITAXON","denotations":[{"id":"T1","span":{"begin":20,"end":25},"obj":"OrganismTaxon"}],"attributes":[{"id":"A1","pred":"db_id","subj":"T1","obj":"9606"}],"text":"Cloning a cDNA from human NK/T cells which codes for a protein with high proline content.\nA cDNA clone, B4-2, was isolated from a natural killer (NK) minus T cell subtractive library. The B4-2 clone coded for an mRNA of 2061 bp in length. It encodes a deduced 327 aa protein with a calculated molecular mass of 35.2 kDa. Searching of B4-2 DNA and protein sequences against various databases revealed no high homology to other sequences. However, B4-2 has an unusually high proline content (13%), contains a putative nuclear targeting sequence, and has several SPXX motifs which are frequently found in gene regulatory proteins. One of the stretches of prolines in B4-2 closely resembles the ligand for proteins with SH3 domains. Northern hybridization data showed that B4-2 is not a lymphoid specific gene and is expressed in a hepatoma cell line and also weakly transcribed or absent in a variety of other cells. A polyclonal antiserum raised against recombinant B4-2 recognizes a 32-34 kDa protein in lymphocytes."}

{"project":"Anatomy-UBERON","denotations":[{"id":"T1","span":{"begin":156,"end":162},"obj":"Body_part"},{"id":"T2","span":{"begin":1003,"end":1014},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"uberon_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"A2","pred":"uberon_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/CL_0000542"}],"text":"Cloning a cDNA from human NK/T cells which codes for a protein with high proline content.\nA cDNA clone, B4-2, was isolated from a natural killer (NK) minus T cell subtractive library. The B4-2 clone coded for an mRNA of 2061 bp in length. It encodes a deduced 327 aa protein with a calculated molecular mass of 35.2 kDa. Searching of B4-2 DNA and protein sequences against various databases revealed no high homology to other sequences. However, B4-2 has an unusually high proline content (13%), contains a putative nuclear targeting sequence, and has several SPXX motifs which are frequently found in gene regulatory proteins. One of the stretches of prolines in B4-2 closely resembles the ligand for proteins with SH3 domains. Northern hybridization data showed that B4-2 is not a lymphoid specific gene and is expressed in a hepatoma cell line and also weakly transcribed or absent in a variety of other cells. A polyclonal antiserum raised against recombinant B4-2 recognizes a 32-34 kDa protein in lymphocytes."}

{"project":"CL-cell","denotations":[{"id":"T1","span":{"begin":29,"end":36},"obj":"Cell"},{"id":"T2","span":{"begin":156,"end":162},"obj":"Cell"},{"id":"T3","span":{"begin":1003,"end":1014},"obj":"Cell"}],"attributes":[{"id":"A1","pred":"cl_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/CL:0000084"},{"id":"A2","pred":"cl_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/CL:0000084"},{"id":"A3","pred":"cl_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/CL:0000542"}],"text":"Cloning a cDNA from human NK/T cells which codes for a protein with high proline content.\nA cDNA clone, B4-2, was isolated from a natural killer (NK) minus T cell subtractive library. The B4-2 clone coded for an mRNA of 2061 bp in length. It encodes a deduced 327 aa protein with a calculated molecular mass of 35.2 kDa. Searching of B4-2 DNA and protein sequences against various databases revealed no high homology to other sequences. However, B4-2 has an unusually high proline content (13%), contains a putative nuclear targeting sequence, and has several SPXX motifs which are frequently found in gene regulatory proteins. One of the stretches of prolines in B4-2 closely resembles the ligand for proteins with SH3 domains. Northern hybridization data showed that B4-2 is not a lymphoid specific gene and is expressed in a hepatoma cell line and also weakly transcribed or absent in a variety of other cells. A polyclonal antiserum raised against recombinant B4-2 recognizes a 32-34 kDa protein in lymphocytes."}