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PubMed:7575565 JSONTXT

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DisGeNET

Id Subject Object Predicate Lexical cue
T0 15-19 gene:55278 denotes GATA
T1 48-52 disease:C0271994 denotes HPFH
T2 0-5 gene:3146 denotes HMG-I
T3 48-52 disease:C0271994 denotes HPFH
T4 0-5 gene:10354 denotes HMG-I
T5 48-52 disease:C0271994 denotes HPFH
T6 712-717 gene:3146 denotes HMG-I
T7 725-729 disease:C0271994 denotes HPFH
T8 712-717 gene:10354 denotes HMG-I
T9 725-729 disease:C0271994 denotes HPFH
R1 T0 T1 associated_with GATA,HPFH
R2 T2 T3 associated_with HMG-I,HPFH
R3 T4 T5 associated_with HMG-I,HPFH
R4 T6 T7 associated_with HMG-I,HPFH
R5 T8 T9 associated_with HMG-I,HPFH

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 0-5 protein denotes HMG-I
T2 15-26 DNA denotes GATA motifs
T3 95-110 protein denotes nuclear protein
T4 111-116 protein denotes HMG-I
T5 124-151 DNA denotes human gamma-globin promoter
T6 166-171 protein denotes HMG-I
T7 221-232 DNA denotes GATA motifs
T8 240-261 DNA denotes gamma-globin promoter
T9 297-320 protein denotes erythroid factor GATA-1
T10 385-390 protein denotes HMG-I
T11 420-432 protein denotes gamma-globin
T12 436-457 cell_type denotes adult red blood cells
T13 459-463 cell_type denotes HPFH
T14 490-511 DNA denotes gamma-globin promoter
T15 543-548 protein denotes HMG-I
T16 571-586 DNA denotes mutant sequence
T17 600-611 DNA denotes GATA motifs
T18 623-642 DNA denotes globin cis-elements
T19 656-661 protein denotes HMG-I
T20 712-717 protein denotes HMG-I
T21 725-729 cell_type denotes HPFH
T22 798-820 protein denotes multiprotein complexes

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 0-5 NP denotes HMG-I
C2 91-116 NP denotes the nuclear protein HMG-I
C3 120-151 NP denotes the human gamma-globin promoter
C4 166-171 NP denotes HMG-I
C5 211-232 NP denotes a pair of GATA motifs
C6 236-261 NP denotes the gamma-globin promoter
C7 263-280 NP denotes this paired motif
C9 385-390 NP denotes HMG-I
C8 322-390 NP denotes A naturally occurring mutation (-175 T-C) in the area bound by HMG-I
C10 486-511 NP denotes the gamma-globin promoter
C11 543-548 NP denotes HMG-I
C12 566-586 NP denotes this mutant sequence
C13 600-642 NP denotes GATA motifs from other globin cis-elements
C14 656-661 NP denotes HMG-I
C15 681-685 NP denotes them
C16 712-717 NP denotes HMG-I
C17 759-761 NP denotes it
C18 798-820 NP denotes multiprotein complexes
C19 821-825 NP denotes that
R1 C2 C1 coref-ident the nuclear protein HMG-I,HMG-I
R2 C4 C2 coref-ident HMG-I,the nuclear protein HMG-I
R3 C6 C3 coref-ident the gamma-globin promoter,the human gamma-globin promoter
R4 C7 C5 coref-ident this paired motif,a pair of GATA motifs
R5 C9 C4 coref-ident HMG-I,HMG-I
R6 C10 C6 coref-ident the gamma-globin promoter,the gamma-globin promoter
R7 C11 C9 coref-ident HMG-I,HMG-I
R8 C12 C8 coref-ident this mutant sequence,A naturally occurring mutation (-175 T-C) in the area bound by HMG-I
R9 C14 C11 coref-ident HMG-I,HMG-I
R10 C15 C13 coref-pron them,GATA motifs from other globin cis-elements
R11 C16 C14 coref-ident HMG-I,HMG-I
R12 C17 C16 coref-pron it,HMG-I
R13 C19 C18 coref-relat that,multiprotein complexes

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-62 Sentence denotes HMG-I binds to GATA motifs: implications for an HPFH syndrome.
S2 63-152 Sentence denotes We have examined binding of the nuclear protein HMG-I to the human gamma-globin promoter.
S3 153-321 Sentence denotes We find that HMG-I binds preferentially to the more 3' of a pair of GATA motifs in the gamma-globin promoter; this paired motif is bound by the erythroid factor GATA-1.
S4 322-587 Sentence denotes A naturally occurring mutation (-175 T-C) in the area bound by HMG-I results in overexpression of gamma-globin in adult red blood cells (HPFH) and up-regulation of the gamma-globin promoter in in vitro expression assays; HMG-I does not bind to this mutant sequence.
S5 588-686 Sentence denotes A survey of GATA motifs from other globin cis-elements demonstrates HMG-I binding to most of them.
S6 687-858 Sentence denotes These findings implicate HMG-I in the HPFH phenotype; we speculate that it may participate in the formation of multiprotein complexes that regulate globin gene expression.

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 0-5 protein_molecule denotes HMG-I
T2 15-26 DNA_domain_or_region denotes GATA motifs
T3 48-61 other_name denotes HPFH syndrome
T4 95-110 protein_family_or_group denotes nuclear protein
T5 111-116 protein_molecule denotes HMG-I
T6 124-151 DNA_domain_or_region denotes human gamma-globin promoter
T7 166-171 protein_molecule denotes HMG-I
T8 221-232 DNA_domain_or_region denotes GATA motifs
T9 240-261 DNA_domain_or_region denotes gamma-globin promoter
T10 297-313 protein_family_or_group denotes erythroid factor
T11 314-320 protein_molecule denotes GATA-1
T12 344-352 other_name denotes mutation
T13 385-390 protein_molecule denotes HMG-I
T14 420-432 protein_family_or_group denotes gamma-globin
T15 436-457 cell_type denotes adult red blood cells
T16 459-463 cell_type denotes HPFH
T17 490-502 protein_family_or_group denotes gamma-globin
T18 515-541 other_name denotes in vitro expression assays
T19 543-548 protein_molecule denotes HMG-I
T20 571-586 DNA_domain_or_region denotes mutant sequence
T21 600-611 DNA_domain_or_region denotes GATA motifs
T22 623-642 DNA_domain_or_region denotes globin cis-elements
T23 656-661 protein_molecule denotes HMG-I
T24 712-717 protein_molecule denotes HMG-I
T25 725-729 cell_type denotes HPFH
T26 798-820 protein_complex denotes multiprotein complexes
T27 835-841 other_name denotes globin
T28 842-857 other_name denotes gene expression