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Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-136 Sentence denotes Regulation of human immunodeficiency virus type 1 and cytokine gene expression in myeloid cells by NF-kappa B/Rel transcription factors.
T2 137-371 Sentence denotes CD4+ macrophages in tissues such as lung, skin, and lymph nodes, promyelocytic cells in bone marrow, and peripheral blood monocytes serve as important targets and reservoirs for human immunodeficiency virus type 1 (HIV-1) replication.
T3 372-509 Sentence denotes HIV-1-infected myeloid cells are often diminished in their ability to participate in chemotaxis, phagocytosis, and intracellular killing.
T4 510-783 Sentence denotes HIV-1 infection of myeloid cells can lead to the expression of surface receptors associated with cellular activation and/or differentiation that increase the responsiveness of these cells to cytokines secreted by neighboring cells as well as to bacteria or other pathogens.
T5 784-923 Sentence denotes Enhancement of HIV-1 replication is related in part to increased DNA-binding activity of cellular transcription factors such as NF-kappa B.
T6 924-1101 Sentence denotes NF-kappa B binds to the HIV-1 enhancer region of the long terminal repeat and contributes to the inducibility of HIV-1 gene expression in response to multiple activating agents.
T7 1102-1262 Sentence denotes Phosphorylation and degradation of the cytoplasmic inhibitor I kappa B alpha are crucial regulatory events in the activation of NF-kappa B DNA-binding activity.
T8 1263-1360 Sentence denotes Both N- and C-terminal residues of I kappa B alpha are required for inducer-mediated degradation.
T9 1361-1539 Sentence denotes Chronic HIV-1 infection of myeloid cells leads to constitutive NF-kappa B DNA-binding activity and provides an intranuclear environment capable of perpetuating HIV-1 replication.
T10 1540-1679 Sentence denotes Increased intracellular stores of latent NF-kappa B may also result in rapid inducibility of NF-kappa B-dependent cytokine gene expression.
T11 1680-1906 Sentence denotes In response to secondary pathogenic infections or antigenic challenge, cytokine gene expression is rapidly induced, enhanced, and sustained over prolonged periods in HIV-1-infected myeloid cells compared with uninfected cells.
T12 1907-2018 Sentence denotes Elevated levels of several inflammatory cytokines have been detected in the sera of HIV-1-infected individuals.
T13 2019-2142 Sentence denotes Secretion of myeloid cell-derived cytokines may both increase virus production and contribute to AIDS-associated disorders.
T1 0-136 Sentence denotes Regulation of human immunodeficiency virus type 1 and cytokine gene expression in myeloid cells by NF-kappa B/Rel transcription factors.
T2 137-371 Sentence denotes CD4+ macrophages in tissues such as lung, skin, and lymph nodes, promyelocytic cells in bone marrow, and peripheral blood monocytes serve as important targets and reservoirs for human immunodeficiency virus type 1 (HIV-1) replication.
T3 372-509 Sentence denotes HIV-1-infected myeloid cells are often diminished in their ability to participate in chemotaxis, phagocytosis, and intracellular killing.
T4 510-783 Sentence denotes HIV-1 infection of myeloid cells can lead to the expression of surface receptors associated with cellular activation and/or differentiation that increase the responsiveness of these cells to cytokines secreted by neighboring cells as well as to bacteria or other pathogens.
T5 784-923 Sentence denotes Enhancement of HIV-1 replication is related in part to increased DNA-binding activity of cellular transcription factors such as NF-kappa B.
T6 924-1101 Sentence denotes NF-kappa B binds to the HIV-1 enhancer region of the long terminal repeat and contributes to the inducibility of HIV-1 gene expression in response to multiple activating agents.
T7 1102-1262 Sentence denotes Phosphorylation and degradation of the cytoplasmic inhibitor I kappa B alpha are crucial regulatory events in the activation of NF-kappa B DNA-binding activity.
T8 1263-1360 Sentence denotes Both N- and C-terminal residues of I kappa B alpha are required for inducer-mediated degradation.
T9 1361-1539 Sentence denotes Chronic HIV-1 infection of myeloid cells leads to constitutive NF-kappa B DNA-binding activity and provides an intranuclear environment capable of perpetuating HIV-1 replication.
T10 1540-1679 Sentence denotes Increased intracellular stores of latent NF-kappa B may also result in rapid inducibility of NF-kappa B-dependent cytokine gene expression.
T11 1680-1906 Sentence denotes In response to secondary pathogenic infections or antigenic challenge, cytokine gene expression is rapidly induced, enhanced, and sustained over prolonged periods in HIV-1-infected myeloid cells compared with uninfected cells.
T12 1907-2018 Sentence denotes Elevated levels of several inflammatory cytokines have been detected in the sera of HIV-1-infected individuals.
T13 2019-2142 Sentence denotes Secretion of myeloid cell-derived cytokines may both increase virus production and contribute to AIDS-associated disorders.

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 82-95 cell_type denotes myeloid cells
T2 99-113 protein denotes NF-kappa B/Rel
T3 114-135 protein denotes transcription factors
T4 137-153 cell_line denotes CD4+ macrophages
T5 202-221 cell_type denotes promyelocytic cells
T6 242-268 cell_type denotes peripheral blood monocytes
T7 387-400 cell_type denotes myeloid cells
T8 529-542 cell_type denotes myeloid cells
T9 573-590 protein denotes surface receptors
T10 701-710 protein denotes cytokines
T11 873-903 protein denotes cellular transcription factors
T12 912-922 protein denotes NF-kappa B
T13 924-934 protein denotes NF-kappa B
T14 948-962 DNA denotes HIV-1 enhancer
T15 977-997 DNA denotes long terminal repeat
T16 1141-1162 protein denotes cytoplasmic inhibitor
T17 1163-1172 protein denotes I kappa B
T18 1230-1240 protein denotes NF-kappa B
T19 1298-1307 protein denotes I kappa B
T20 1388-1401 cell_type denotes myeloid cells
T21 1424-1434 protein denotes NF-kappa B
T22 1574-1591 protein denotes latent NF-kappa B
T23 1633-1643 protein denotes NF-kappa B
T24 1654-1662 protein denotes cytokine
T25 1751-1759 protein denotes cytokine
T26 1846-1874 cell_line denotes HIV-1-infected myeloid cells
T27 1889-1905 cell_type denotes uninfected cells
T28 1934-1956 protein denotes inflammatory cytokines
T29 2032-2062 protein denotes myeloid cell-derived cytokines

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 82-95 NP denotes myeloid cells
C2 315-370 NP denotes human immunodeficiency virus type 1 (HIV-1) replication
C3 372-400 NP denotes HIV-1-infected myeloid cells
C4 425-430 NP denotes their
C5 529-542 NP denotes myeloid cells
C6 573-649 NP denotes surface receptors associated with cellular activation and/or differentiation
C7 650-654 NP denotes that
C8 686-697 NP denotes these cells
C9 799-816 NP denotes HIV-1 replication
C10 912-922 NP denotes NF-kappa B
C11 924-934 NP denotes NF-kappa B
C12 1137-1178 NP denotes the cytoplasmic inhibitor I kappa B alpha
C13 1298-1313 NP denotes I kappa B alpha
C14 1388-1401 NP denotes myeloid cells
C15 1521-1538 NP denotes HIV-1 replication
C16 1633-1678 NP denotes NF-kappa B-dependent cytokine gene expression
C17 1751-1775 NP denotes cytokine gene expression
C18 1846-1874 NP denotes HIV-1-infected myeloid cells
R1 C4 C3 coref-pron their,HIV-1-infected myeloid cells
R2 C5 C1 coref-ident myeloid cells,myeloid cells
R3 C7 C6 coref-relat that,surface receptors associated with cellular activation and/or differentiation
R4 C8 C5 coref-ident these cells,myeloid cells
R5 C9 C2 coref-ident HIV-1 replication,human immunodeficiency virus type 1 (HIV-1) replication
R6 C11 C10 coref-ident NF-kappa B,NF-kappa B
R7 C13 C12 coref-ident I kappa B alpha,the cytoplasmic inhibitor I kappa B alpha
R8 C14 C5 coref-ident myeloid cells,myeloid cells
R9 C15 C9 coref-ident HIV-1 replication,HIV-1 replication
R10 C17 C16 coref-ident cytokine gene expression,NF-kappa B-dependent cytokine gene expression
R11 C18 C3 coref-ident HIV-1-infected myeloid cells,HIV-1-infected myeloid cells

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-136 Sentence denotes Regulation of human immunodeficiency virus type 1 and cytokine gene expression in myeloid cells by NF-kappa B/Rel transcription factors.
S2 137-371 Sentence denotes CD4+ macrophages in tissues such as lung, skin, and lymph nodes, promyelocytic cells in bone marrow, and peripheral blood monocytes serve as important targets and reservoirs for human immunodeficiency virus type 1 (HIV-1) replication.
S3 372-509 Sentence denotes HIV-1-infected myeloid cells are often diminished in their ability to participate in chemotaxis, phagocytosis, and intracellular killing.
S4 510-783 Sentence denotes HIV-1 infection of myeloid cells can lead to the expression of surface receptors associated with cellular activation and/or differentiation that increase the responsiveness of these cells to cytokines secreted by neighboring cells as well as to bacteria or other pathogens.
S5 784-923 Sentence denotes Enhancement of HIV-1 replication is related in part to increased DNA-binding activity of cellular transcription factors such as NF-kappa B.
S6 924-1101 Sentence denotes NF-kappa B binds to the HIV-1 enhancer region of the long terminal repeat and contributes to the inducibility of HIV-1 gene expression in response to multiple activating agents.
S7 1102-1262 Sentence denotes Phosphorylation and degradation of the cytoplasmic inhibitor I kappa B alpha are crucial regulatory events in the activation of NF-kappa B DNA-binding activity.
S8 1263-1360 Sentence denotes Both N- and C-terminal residues of I kappa B alpha are required for inducer-mediated degradation.
S9 1361-1539 Sentence denotes Chronic HIV-1 infection of myeloid cells leads to constitutive NF-kappa B DNA-binding activity and provides an intranuclear environment capable of perpetuating HIV-1 replication.
S10 1540-1679 Sentence denotes Increased intracellular stores of latent NF-kappa B may also result in rapid inducibility of NF-kappa B-dependent cytokine gene expression.
S11 1680-1906 Sentence denotes In response to secondary pathogenic infections or antigenic challenge, cytokine gene expression is rapidly induced, enhanced, and sustained over prolonged periods in HIV-1-infected myeloid cells compared with uninfected cells.
S12 1907-2018 Sentence denotes Elevated levels of several inflammatory cytokines have been detected in the sera of HIV-1-infected individuals.
S13 2019-2142 Sentence denotes Secretion of myeloid cell-derived cytokines may both increase virus production and contribute to AIDS-associated disorders.

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 14-49 virus denotes human immunodeficiency virus type 1
T2 63-78 other_name denotes gene expression
T3 82-95 cell_type denotes myeloid cells
T4 99-109 protein_molecule denotes NF-kappa B
T5 114-135 protein_family_or_group denotes transcription factors
T6 137-153 cell_line denotes CD4+ macrophages
T7 173-177 body_part denotes lung
T8 179-183 body_part denotes skin
T9 189-200 body_part denotes lymph nodes
T10 202-221 cell_type denotes promyelocytic cells
T11 225-236 tissue denotes bone marrow
T12 242-268 cell_type denotes peripheral blood monocytes
T13 315-350 virus denotes human immunodeficiency virus type 1
T14 352-357 virus denotes HIV-1
T15 372-377 virus denotes HIV-1
T16 387-400 cell_type denotes myeloid cells
T17 457-467 other_name denotes chemotaxis
T18 469-481 other_name denotes phagocytosis
T19 487-508 other_name denotes intracellular killing
T20 510-515 virus denotes HIV-1
T21 529-542 cell_type denotes myeloid cells
T22 573-590 protein_family_or_group denotes surface receptors
T23 607-626 other_name denotes cellular activation
T24 634-649 other_name denotes differentiation
T25 701-710 protein_family_or_group denotes cytokines
T26 755-763 mono_cell denotes bacteria
T27 799-804 virus denotes HIV-1
T28 849-869 other_name denotes DNA-binding activity
T29 873-881 protein_family_or_group denotes cellular
T30 882-903 protein_family_or_group denotes transcription factors
T31 912-922 protein_molecule denotes NF-kappa B
T32 924-934 protein_molecule denotes NF-kappa B
T33 948-953 virus denotes HIV-1
T34 977-997 DNA_domain_or_region denotes long terminal repeat
T35 1037-1042 virus denotes HIV-1
T36 1043-1058 other_name denotes gene expression
T37 1102-1117 other_name denotes Phosphorylation
T38 1122-1133 other_name denotes degradation
T39 1141-1162 protein_family_or_group denotes cytoplasmic inhibitor
T40 1163-1172 protein_molecule denotes I kappa B
T41 1230-1240 protein_molecule denotes NF-kappa B
T42 1241-1261 other_name denotes DNA-binding activity
T43 1298-1307 protein_molecule denotes I kappa B
T44 1331-1359 other_name denotes inducer-mediated degradation
T45 1369-1374 virus denotes HIV-1
T46 1388-1401 cell_type denotes myeloid cells
T47 1424-1434 protein_molecule denotes NF-kappa B
T48 1435-1455 other_name denotes DNA-binding activity
T49 1472-1496 other_name denotes intranuclear environment
T50 1521-1526 virus denotes HIV-1
T51 1550-1570 other_name denotes intracellular stores
T52 1574-1580 protein_molecule denotes latent
T53 1581-1591 protein_molecule denotes NF-kappa B
T54 1633-1643 protein_molecule denotes NF-kappa B
T55 1654-1662 protein_family_or_group denotes cytokine
T56 1663-1678 other_name denotes gene expression
T57 1751-1759 protein_family_or_group denotes cytokine
T58 1760-1775 other_name denotes gene expression
T59 1846-1851 virus denotes HIV-1
T60 1861-1874 cell_type denotes myeloid cells
T61 1889-1905 cell_type denotes uninfected cells
T62 1934-1956 protein_family_or_group denotes inflammatory cytokines
T63 1991-1996 virus denotes HIV-1
T64 2032-2052 protein_family_or_group denotes myeloid cell-derived
T65 2053-2062 protein_family_or_group denotes cytokines
T66 2081-2097 other_name denotes virus production
T67 2116-2141 other_name denotes AIDS-associated disorders