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PubMed:7543076 JSONTXT

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Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-150 Sentence denotes Lipopolysaccharide-induced E-selectin expression requires continuous presence of LPS and is inhibited by bactericidal/permeability-increasing protein.
T2 151-290 Sentence denotes Endothelial cells stimulated by LPS express E-selectin, which plays an important role in mediating neutrophil adhesion during inflammation.
T3 291-593 Sentence denotes E-selectin is induced within 1-2 h, peaks at 4-6 h, and gradually returns to basal level by 24 h. rBPI21, a recombinant N-terminal fragment of human bactericidal/permeability-increasing protein (BPI), inhibited LPS-induced E-selectin expression when added at the same time as, and up to 6 h after, LPS.
T4 594-699 Sentence denotes Delayed administration of rBPI21 also affected LPS-mediated activation of the nuclear factor, NF-kappa B.
T5 700-880 Sentence denotes Two to 4 h following LPS addition to endothelial cells, when NF-kappa B was already activated, addition of rBPI21 resulted in marked reduction of NF-kappa B detectable at 4 or 6 h.
T6 881-1072 Sentence denotes These results indicate that endothelial activation requires continuous presence of LPS, and rBPI21 acts to reverse LPS-mediated endothelial activation by interrupting the on-going LPS signal.
T1 0-150 Sentence denotes Lipopolysaccharide-induced E-selectin expression requires continuous presence of LPS and is inhibited by bactericidal/permeability-increasing protein.
T2 151-290 Sentence denotes Endothelial cells stimulated by LPS express E-selectin, which plays an important role in mediating neutrophil adhesion during inflammation.
T3 291-593 Sentence denotes E-selectin is induced within 1-2 h, peaks at 4-6 h, and gradually returns to basal level by 24 h. rBPI21, a recombinant N-terminal fragment of human bactericidal/permeability-increasing protein (BPI), inhibited LPS-induced E-selectin expression when added at the same time as, and up to 6 h after, LPS.
T4 594-699 Sentence denotes Delayed administration of rBPI21 also affected LPS-mediated activation of the nuclear factor, NF-kappa B.
T5 700-880 Sentence denotes Two to 4 h following LPS addition to endothelial cells, when NF-kappa B was already activated, addition of rBPI21 resulted in marked reduction of NF-kappa B detectable at 4 or 6 h.
T6 881-1072 Sentence denotes These results indicate that endothelial activation requires continuous presence of LPS, and rBPI21 acts to reverse LPS-mediated endothelial activation by interrupting the on-going LPS signal.

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 27-37 protein denotes E-selectin
T2 105-149 protein denotes bactericidal/permeability-increasing protein
T3 151-168 cell_type denotes Endothelial cells
T4 195-205 protein denotes E-selectin
T5 250-260 cell_type denotes neutrophil
T6 291-301 protein denotes E-selectin
T7 389-395 protein denotes rBPI21
T8 399-430 protein denotes recombinant N-terminal fragment
T9 434-484 protein denotes human bactericidal/permeability-increasing protein
T10 486-489 protein denotes BPI
T11 514-524 protein denotes E-selectin
T12 620-626 protein denotes rBPI21
T13 672-686 protein denotes nuclear factor
T14 688-698 protein denotes NF-kappa B
T15 737-754 cell_type denotes endothelial cells
T16 761-771 protein denotes NF-kappa B
T17 807-813 protein denotes rBPI21
T18 846-856 protein denotes NF-kappa B
T19 973-979 protein denotes rBPI21

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 0-48 NP denotes Lipopolysaccharide-induced E-selectin expression
C3 81-84 NP denotes LPS
C2 58-84 NP denotes continuous presence of LPS
C4 105-149 NP denotes bactericidal/permeability-increasing protein
C5 151-168 NP denotes Endothelial cells
C6 183-186 NP denotes LPS
C7 195-205 NP denotes E-selectin
C8 207-212 NP denotes which
C9 291-301 NP denotes E-selectin
C10 389-395 NP denotes rBPI21
C12 434-490 NP denotes human bactericidal/permeability-increasing protein (BPI)
C11 397-490 NP denotes a recombinant N-terminal fragment of human bactericidal/permeability-increasing protein (BPI)
C13 502-535 NP denotes LPS-induced E-selectin expression
C14 589-592 NP denotes LPS
C15 620-626 NP denotes rBPI21
C16 668-686 NP denotes the nuclear factor
C17 688-698 NP denotes NF-kappa B
C18 737-754 NP denotes endothelial cells
C19 761-771 NP denotes NF-kappa B
C20 807-813 NP denotes rBPI21
C21 846-856 NP denotes NF-kappa B
C23 964-967 NP denotes LPS
C22 941-967 NP denotes continuous presence of LPS
C24 973-979 NP denotes rBPI21
R1 C6 C3 coref-ident LPS,LPS
R2 C8 C7 coref-relat which,E-selectin
R3 C9 C7 coref-ident E-selectin,E-selectin
R4 C12 C4 coref-ident human bactericidal/permeability-increasing protein (BPI),bactericidal/permeability-increasing protein
R5 C11 C10 coref-appos a recombinant N-terminal fragment of human bactericidal/permeability-increasing protein (BPI),rBPI21
R6 C13 C1 coref-ident LPS-induced E-selectin expression,Lipopolysaccharide-induced E-selectin expression
R7 C14 C6 coref-ident LPS,LPS
R8 C15 C10 coref-ident rBPI21,rBPI21
R9 C17 C16 coref-appos NF-kappa B,the nuclear factor
R10 C18 C5 coref-ident endothelial cells,Endothelial cells
R11 C19 C16 coref-ident NF-kappa B,the nuclear factor
R12 C20 C15 coref-ident rBPI21,rBPI21
R13 C21 C19 coref-ident NF-kappa B,NF-kappa B
R14 C23 C14 coref-ident LPS,LPS
R15 C22 C2 coref-ident continuous presence of LPS,continuous presence of LPS
R16 C24 C20 coref-ident rBPI21,rBPI21

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-150 Sentence denotes Lipopolysaccharide-induced E-selectin expression requires continuous presence of LPS and is inhibited by bactericidal/permeability-increasing protein.
S2 151-290 Sentence denotes Endothelial cells stimulated by LPS express E-selectin, which plays an important role in mediating neutrophil adhesion during inflammation.
S3 291-388 Sentence denotes E-selectin is induced within 1-2 h, peaks at 4-6 h, and gradually returns to basal level by 24 h.
S4 389-593 Sentence denotes rBPI21, a recombinant N-terminal fragment of human bactericidal/permeability-increasing protein (BPI), inhibited LPS-induced E-selectin expression when added at the same time as, and up to 6 h after, LPS.
S5 594-699 Sentence denotes Delayed administration of rBPI21 also affected LPS-mediated activation of the nuclear factor, NF-kappa B.
S6 700-880 Sentence denotes Two to 4 h following LPS addition to endothelial cells, when NF-kappa B was already activated, addition of rBPI21 resulted in marked reduction of NF-kappa B detectable at 4 or 6 h.
S7 881-1072 Sentence denotes These results indicate that endothelial activation requires continuous presence of LPS, and rBPI21 acts to reverse LPS-mediated endothelial activation by interrupting the on-going LPS signal.

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 0-18 lipid denotes Lipopolysaccharide
T2 27-37 protein_molecule denotes E-selectin
T3 81-84 lipid denotes LPS
T4 105-149 protein_family_or_group denotes bactericidal/permeability-increasing protein
T5 151-168 cell_type denotes Endothelial cells
T6 183-186 lipid denotes LPS
T7 195-205 protein_molecule denotes E-selectin
T8 250-260 cell_type denotes neutrophil
T9 277-289 other_name denotes inflammation
T10 291-301 protein_molecule denotes E-selectin
T11 389-395 protein_molecule denotes rBPI21
T12 399-430 protein_family_or_group denotes recombinant N-terminal fragment
T13 434-484 protein_molecule denotes human bactericidal/permeability-increasing protein
T14 486-489 protein_molecule denotes BPI
T15 502-505 lipid denotes LPS
T16 514-524 protein_molecule denotes E-selectin
T17 589-592 lipid denotes LPS
T18 620-626 protein_molecule denotes rBPI21
T19 641-644 lipid denotes LPS
T20 672-686 protein_family_or_group denotes nuclear factor
T21 688-698 protein_molecule denotes NF-kappa B
T22 721-724 lipid denotes LPS
T23 737-754 cell_type denotes endothelial cells
T24 761-771 protein_molecule denotes NF-kappa B
T25 807-813 protein_molecule denotes rBPI21
T26 846-856 protein_molecule denotes NF-kappa B
T27 909-931 other_name denotes endothelial activation
T28 964-967 lipid denotes LPS
T29 973-979 protein_molecule denotes rBPI21
T30 996-999 lipid denotes LPS
T31 1052-1060 other_name denotes on-going
T32 1061-1064 lipid denotes LPS