PubMed:7540942
Annnotations
jnlpba-st-training
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 17-21 | protein | denotes | CD30 |
| T2 | 69-76 | cell_type | denotes | T cells |
| T3 | 78-82 | protein | denotes | CD30 |
| T4 | 334-338 | protein | denotes | CD30 |
| T5 | 352-356 | protein | denotes | CD30 |
| T6 | 443-454 | protein | denotes | CD30 ligand |
| T7 | 456-461 | protein | denotes | CD30L |
| T8 | 491-495 | protein | denotes | CD30 |
| T9 | 542-553 | cell_line | denotes | ACH-2 cells |
| T10 | 620-634 | protein | denotes | TNF alpha/beta |
| T11 | 666-670 | protein | denotes | CD30 |
| T12 | 680-690 | protein | denotes | NF-kappa B |
| T13 | 740-744 | protein | denotes | CD30 |
| T14 | 744-750 | protein | denotes | -CD30L |
| T15 | 858-861 | protein | denotes | TNF |
| T16 | 954-966 | cell_line | denotes | CD4+ T cells |
genia-medco-coref
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| C2 | 17-21 | NP | denotes | CD30 |
| C1 | 0-21 | NP | denotes | Cross-linking of CD30 |
| C3 | 30-44 | NP | denotes | HIV expression |
| C4 | 78-82 | NP | denotes | CD30 |
| C5 | 84-143 | NP | denotes | a member of the tumor necrosis factor (TNF) receptor family |
| C6 | 191-218 | NP | denotes | the human T cell line ACH-2 |
| C7 | 220-225 | NP | denotes | which |
| C8 | 334-338 | NP | denotes | CD30 |
| C9 | 344-385 | NP | denotes | an anti-CD30-specific monoclonal antibody |
| C10 | 387-392 | NP | denotes | which |
| C11 | 475-489 | NP | denotes | HIV expression |
| C12 | 491-509 | NP | denotes | CD30 cross-linking |
| C14 | 575-589 | NP | denotes | HIV expression |
| C13 | 558-589 | NP | denotes | the induction of HIV expression |
| C16 | 666-670 | NP | denotes | CD30 |
| C15 | 649-670 | NP | denotes | cross-linking of CD30 |
| C18 | 789-803 | NP | denotes | HIV expression |
| C17 | 772-803 | NP | denotes | the induction of HIV expression |
| C19 | 807-834 | NP | denotes | a kappa B-dependent pathway |
| C20 | 835-839 | NP | denotes | that |
| C21 | 916-930 | NP | denotes | HIV expression |
| C22 | 982-997 | NP | denotes | lymphoid organs |
| C23 | 998-1003 | NP | denotes | where |
| R6 | C11 | C3 | coref-ident | HIV expression,HIV expression |
| R7 | C12 | C1 | coref-ident | CD30 cross-linking,Cross-linking of CD30 |
| R8 | C14 | C11 | coref-ident | HIV expression,HIV expression |
| R9 | C16 | C8 | coref-ident | CD30,CD30 |
| R1 | C4 | C2 | coref-ident | CD30,CD30 |
| R2 | C5 | C4 | coref-appos | a member of the tumor necrosis factor (TNF) receptor family,CD30 |
| R3 | C7 | C6 | coref-relat | which,the human T cell line ACH-2 |
| R4 | C8 | C4 | coref-ident | CD30,CD30 |
| R5 | C10 | C9 | coref-relat | which,an anti-CD30-specific monoclonal antibody |
| R10 | C15 | C12 | coref-ident | cross-linking of CD30,CD30 cross-linking |
| R11 | C18 | C14 | coref-ident | HIV expression,HIV expression |
| R12 | C17 | C13 | coref-ident | the induction of HIV expression,the induction of HIV expression |
| R13 | C20 | C19 | coref-relat | that,a kappa B-dependent pathway |
| R14 | C21 | C18 | coref-ident | HIV expression,HIV expression |
| R15 | C23 | C22 | coref-relat | where,lymphoid organs |
pubmed-sentences-benchmark
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| S1 | 0-77 | Sentence | denotes | Cross-linking of CD30 induces HIV expression in chronically infected T cells. |
| S2 | 78-299 | Sentence | denotes | CD30, a member of the tumor necrosis factor (TNF) receptor family, is expressed constitutively on the surface of the human T cell line ACH-2, which is chronically infected with human immunodeficiency virus type-1 (HIV)-1. |
| S3 | 300-490 | Sentence | denotes | We demonstrate that cross-linking CD30 with an anti-CD30-specific monoclonal antibody, which mimics the described biological activities of the CD30 ligand (CD30L), results in HIV expression. |
| S4 | 491-635 | Sentence | denotes | CD30 cross-linking does not alter proliferation of ACH-2 cells and the induction of HIV expression is not mediated by endogenous TNF alpha/beta. |
| S5 | 636-733 | Sentence | denotes | Furthermore, cross-linking of CD30 leads to NF-kappa B activation and enhanced HIV transcription. |
| S6 | 734-862 | Sentence | denotes | Thus, CD30-CD30L interactions mediate the induction of HIV expression by a kappa B-dependent pathway that is independent of TNF. |
| S7 | 863-1070 | Sentence | denotes | This mechanism may be important in the activation of HIV expression from latently infected CD4+ T cells, especially in lymphoid organs where cell to cell contact is conducive to receptor-ligand interactions. |
GENIAcorpus
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 17-21 | protein_molecule | denotes | CD30 |
| T2 | 30-33 | virus | denotes | HIV |
| T3 | 69-76 | cell_type | denotes | T cells |
| T4 | 78-82 | protein_molecule | denotes | CD30 |
| T5 | 292-295 | virus | denotes | HIV |
| T6 | 334-338 | protein_molecule | denotes | CD30 |
| T7 | 352-356 | protein_molecule | denotes | CD30 |
| T8 | 443-454 | protein_molecule | denotes | CD30 ligand |
| T9 | 456-461 | protein_molecule | denotes | CD30L |
| T10 | 475-478 | virus | denotes | HIV |
| T11 | 491-495 | protein_molecule | denotes | CD30 |
| T12 | 542-553 | cell_line | denotes | ACH-2 cells |
| T13 | 575-578 | virus | denotes | HIV |
| T14 | 620-634 | protein_molecule | denotes | TNF alpha/beta |
| T15 | 666-670 | protein_molecule | denotes | CD30 |
| T16 | 680-690 | protein_molecule | denotes | NF-kappa B |
| T17 | 715-718 | virus | denotes | HIV |
| T18 | 740-744 | protein_molecule | denotes | CD30 |
| T19 | 744-750 | protein_molecule | denotes | -CD30L |
| T20 | 789-792 | virus | denotes | HIV |
| T21 | 809-834 | other_name | denotes | kappa B-dependent pathway |
| T22 | 858-861 | protein_family_or_group | denotes | TNF |
| T23 | 916-919 | virus | denotes | HIV |
| T24 | 954-958 | cell_line | denotes | CD4+ |
| T25 | 959-966 | cell_type | denotes | T cells |
| T26 | 982-997 | body_part | denotes | lymphoid organs |
| T27 | 1004-1024 | other_name | denotes | cell to cell contact |
| T28 | 1041-1069 | other_name | denotes | receptor-ligand interactions |