> top > docs > PubMed:7532282 > annotations

PubMed:7532282 JSONTXT

Annnotations TAB JSON ListView MergeView

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 38-53 protein denotes I kappa B alpha
T2 135-161 RNA denotes I kappa B alpha/MAD-3 mRNA
T3 184-205 protein denotes I kappa B alpha/MAD-3
T4 212-232 DNA denotes immediate-early gene
T5 236-251 cell_type denotes human monocytes
T6 430-453 protein denotes I kappa B alpha protein
T7 591-614 protein denotes I kappa B alpha protein
T8 648-688 protein denotes NF-kappa B-related transcription factors
T9 744-754 protein denotes NF-kappa B
T10 768-794 DNA denotes I kappa B alpha/MAD-3 gene
T11 879-905 RNA denotes I kappa B alpha/MAD-3 mRNA
T12 979-989 protein denotes NF-kappa B
T13 1035-1061 DNA denotes I kappa B alpha/MAD-3 gene
T14 1126-1156 DNA denotes immediate-early cytokine genes
T15 1170-1205 DNA denotes interleukin 1 beta (IL-1 beta) gene
T16 1278-1304 DNA denotes I kappa B alpha/MAD-3 gene
T17 1374-1400 RNA denotes I kappa B alpha/MAD-3 mRNA
T18 1438-1442 RNA denotes mRNA
T19 1579-1597 cell_type denotes adherent monocytes
T20 1621-1635 RNA denotes IL-1 beta mRNA
T21 1680-1706 RNA denotes I kappa B alpha/MAD-3 mRNA
T22 1790-1826 RNA denotes monocytic I kappa B alpha/MAD-3 mRNA
T23 1851-1869 cell_type denotes adherent monocytes
T24 1912-1938 RNA denotes I kappa B alpha/MAD-3 mRNA
T25 1991-2017 DNA denotes I kappa B alpha/MAD-3 gene
T26 2106-2132 RNA denotes I kappa B alpha/MAD-3 mRNA
T27 2153-2179 DNA denotes I kappa B alpha/MAD-3 gene
T28 2237-2263 RNA denotes I kappa B alpha/MAD-3 mRNA

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 61-79 NP denotes monocyte adherence
C2 135-168 NP denotes I kappa B alpha/MAD-3 mRNA levels
C3 184-205 NP denotes I kappa B alpha/MAD-3
C4 209-251 NP denotes an immediate-early gene in human monocytes
C5 252-256 NP denotes that
C6 394-411 NP denotes monocyte adhesion
C7 426-453 NP denotes the I kappa B alpha protein
C8 587-614 NP denotes the I kappa B alpha protein
C9 692-719 NP denotes nuclei of adhered monocytes
C10 768-808 NP denotes I kappa B alpha/MAD-3 gene transcription
C11 879-912 NP denotes I kappa B alpha/MAD-3 mRNA levels
C12 942-960 NP denotes monocyte adherence
C13 1031-1061 NP denotes the I kappa B alpha/MAD-3 gene
C14 1247-1264 NP denotes monocyte adhesion
C15 1278-1318 NP denotes I kappa B alpha/MAD-3 gene transcription
C16 1374-1407 NP denotes I kappa B alpha/MAD-3 mRNA levels
C17 1569-1597 NP denotes nuclei of adherent monocytes
C18 1599-1617 NP denotes cytoplasmic levels
C19 1671-1676 NP denotes those
C20 1680-1706 NP denotes I kappa B alpha/MAD-3 mRNA
C21 1912-1938 NP denotes I kappa B alpha/MAD-3 mRNA
C22 1991-2031 NP denotes I kappa B alpha/MAD-3 gene transcription
C23 2106-2132 NP denotes I kappa B alpha/MAD-3 mRNA
C24 2153-2193 NP denotes I kappa B alpha/MAD-3 gene transcription
C25 2237-2263 NP denotes I kappa B alpha/MAD-3 mRNA
R8 C15 C10 coref-ident I kappa B alpha/MAD-3 gene transcription,I kappa B alpha/MAD-3 gene transcription
R9 C16 C11 coref-ident I kappa B alpha/MAD-3 mRNA levels,I kappa B alpha/MAD-3 mRNA levels
R10 C17 C9 coref-ident nuclei of adherent monocytes,nuclei of adhered monocytes
R1 C5 C4 coref-relat that,an immediate-early gene in human monocytes
R2 C6 C1 coref-ident monocyte adhesion,monocyte adherence
R3 C8 C7 coref-ident the I kappa B alpha protein,the I kappa B alpha protein
R4 C11 C2 coref-ident I kappa B alpha/MAD-3 mRNA levels,I kappa B alpha/MAD-3 mRNA levels
R5 C12 C1 coref-ident monocyte adherence,monocyte adherence
R6 C13 C3 coref-ident the I kappa B alpha/MAD-3 gene,I kappa B alpha/MAD-3
R7 C14 C6 coref-ident monocyte adhesion,monocyte adhesion
R11 C19 C18 coref-pron those,cytoplasmic levels
R12 C21 C20 coref-ident I kappa B alpha/MAD-3 mRNA,I kappa B alpha/MAD-3 mRNA
R13 C22 C15 coref-ident I kappa B alpha/MAD-3 gene transcription,I kappa B alpha/MAD-3 gene transcription
R14 C23 C21 coref-ident I kappa B alpha/MAD-3 mRNA,I kappa B alpha/MAD-3 mRNA
R15 C24 C22 coref-ident I kappa B alpha/MAD-3 gene transcription,I kappa B alpha/MAD-3 gene transcription
R16 C25 C23 coref-ident I kappa B alpha/MAD-3 mRNA,I kappa B alpha/MAD-3 mRNA

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-169 Sentence denotes Transcription-independent turnover of I kappa B alpha during monocyte adherence: implications for a translational component regulating I kappa B alpha/MAD-3 mRNA levels.
S2 170-377 Sentence denotes We identified I kappa B alpha/MAD-3 as an immediate-early gene in human monocytes that is expressed in response to a variety of signals, including adhesion, lipopolysaccharide, and phorbol myristate acetate.
S3 378-551 Sentence denotes Within 5 min of monocyte adhesion, the level of the I kappa B alpha protein is markedly diminished but is rapidly replaced in a cycloheximide-sensitive manner within 20 min.
S4 552-720 Sentence denotes Accompanying the rapid turnover of the I kappa B alpha protein is simultaneous translocation of NF-kappa B-related transcription factors to nuclei of adhered monocytes.
S5 721-1062 Sentence denotes The demonstration that NF-kappa B can regulate I kappa B alpha/MAD-3 gene transcription in other cell types suggested that the rapid increase in steady-state I kappa B alpha/MAD-3 mRNA levels we observed within 30 min of monocyte adherence would result from NF-kappa B-dependent transcriptional stimulation of the I kappa B alpha/MAD-3 gene.
S6 1063-1337 Sentence denotes Nuclear run-on analyses indicated that, instead, while several immediate-early cytokine genes, such as the interleukin 1 beta (IL-1 beta) gene, were transcriptionally activated during monocyte adhesion, the rate of I kappa B alpha/MAD-3 gene transcription remained constant.
S7 1338-1464 Sentence denotes The adherence-dependent increase in I kappa B alpha/MAD-3 mRNA levels was also not a consequence of mRNA stabilization events.
S8 1465-1715 Sentence denotes Interestingly, while increases in both IL-1 beta and I kappa B alpha/MAD-3 mRNA levels were detected in nuclei of adherent monocytes, cytoplasmic levels of IL-1 beta mRNA increased during adherence whereas those of I kappa B alpha/MAD-3 mRNA did not.
S9 1716-1834 Sentence denotes Taken together, our data suggest that two interactive mechanisms regulate monocytic I kappa B alpha/MAD-3 mRNA levels.
S10 1835-2032 Sentence denotes We propose that adherent monocytes regulate nuclear processing (or decay) of I kappa B alpha/MAD-3 mRNA, thereby increasing mRNA levels without stimulating I kappa B alpha/MAD-3 gene transcription.
S11 2033-2328 Sentence denotes Moreover, since inhibition of protein synthesis leads to accumulation of I kappa B alpha/MAD-3 mRNA without stimulating I kappa B alpha/MAD-3 gene transcription, we suggest that low cytoplasmic levels of I kappa B alpha/MAD-3 mRNA are maintained by a translation-dependent degradation mechanism.

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 0-34 other_name denotes Transcription-independent turnover
T2 38-53 protein_molecule denotes I kappa B alpha
T3 61-79 other_name denotes monocyte adherence
T4 135-150 protein_molecule denotes I kappa B alpha
T5 150-156 protein_molecule denotes /MAD-3
T6 184-199 protein_molecule denotes I kappa B alpha
T7 212-232 DNA_domain_or_region denotes immediate-early gene
T8 236-251 cell_type denotes human monocytes
T9 317-325 other_name denotes adhesion
T10 327-345 lipid denotes lipopolysaccharide
T11 351-376 other_organic_compound denotes phorbol myristate acetate
T12 394-411 other_name denotes monocyte adhesion
T13 430-445 protein_molecule denotes I kappa B alpha
T14 506-536 other_name denotes cycloheximide-sensitive manner
T15 591-606 protein_molecule denotes I kappa B alpha
T16 648-666 protein_family_or_group denotes NF-kappa B-related
T17 667-688 protein_family_or_group denotes transcription factors
T18 744-754 protein_molecule denotes NF-kappa B
T19 768-783 protein_molecule denotes I kappa B alpha
T20 866-878 other_name denotes steady-state
T21 879-894 protein_molecule denotes I kappa B alpha
T22 942-960 other_name denotes monocyte adherence
T23 979-989 protein_molecule denotes NF-kappa B
T24 1035-1050 protein_molecule denotes I kappa B alpha
T25 1126-1156 DNA_family_or_group denotes immediate-early cytokine genes
T26 1170-1188 protein_molecule denotes interleukin 1 beta
T27 1190-1199 protein_molecule denotes IL-1 beta
T28 1247-1264 other_name denotes monocyte adhesion
T29 1278-1293 protein_molecule denotes I kappa B alpha
T30 1374-1389 protein_molecule denotes I kappa B alpha
T31 1438-1442 RNA_family_or_group denotes mRNA
T32 1569-1575 cell_component denotes nuclei
T33 1579-1597 cell_type denotes adherent monocytes
T34 1599-1617 other_name denotes cytoplasmic levels
T35 1621-1630 protein_molecule denotes IL-1 beta
T36 1680-1695 protein_molecule denotes I kappa B alpha
T37 1790-1799 RNA_molecule denotes monocytic
T38 1800-1815 protein_molecule denotes I kappa B alpha
T39 1851-1869 cell_type denotes adherent monocytes
T40 1912-1927 protein_molecule denotes I kappa B alpha
T41 1991-2006 protein_molecule denotes I kappa B alpha
T42 2106-2121 protein_molecule denotes I kappa B alpha
T43 2153-2168 protein_molecule denotes I kappa B alpha
T44 2215-2233 other_name denotes cytoplasmic levels
T45 2237-2252 protein_molecule denotes I kappa B alpha
T46 2284-2327 other_name denotes translation-dependent degradation mechanism