PubMed:6425294
Annnotations
GlyCosmos6-Glycan-Motif-Image
Id | Subject | Object | Predicate | Lexical cue | image |
---|---|---|---|---|---|
T1 | 41-62 | Glycan_Motif | denotes | N-acetylgalactosamine | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G27025MB |
T2 | 64-85 | Glycan_Motif | denotes | globotriaosylceramide | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00059MO |
T3 | 160-169 | Glycan_Motif | denotes | P antigen | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00061MO |
T4 | 334-344 | Glycan_Motif | denotes | Pk antigen | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00059MO |
T5 | 350-359 | Glycan_Motif | denotes | P antigen | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00061MO |
T6 | 524-545 | Glycan_Motif | denotes | globotriaosylceramide | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00059MO |
T7 | 922-943 | Glycan_Motif | denotes | globotriaosylceramide | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00059MO |
T8 | 1361-1380 | Glycan_Motif | denotes | Forssman glycolipid | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G80062GG|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00064MO |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-190 | Sentence | denotes | Purification and characterization of UDP-N-acetylgalactosamine: globotriaosylceramide beta-3-N-acetylgalactosaminyltransferase, a synthase of human blood group P antigen, from canine spleen. |
T2 | 191-561 | Sentence | denotes | A UDP-N-acetylgalactosamine:globotriaosylceramide beta-3-N-acetylgalactosaminyltransferase which catalyzes the conversion of human blood group Pk antigen into P antigen has been purified over 18,000-fold in 4% yield from a Triton X-100 extract of canine spleen microsomes by affinity chromatography on UDP-hexanolamine-Sepharose and globotriaosylceramide acid-Sepharose. |
T3 | 562-724 | Sentence | denotes | The purified enzyme migrates as two major bands with apparent molecular weights of 64,000 and 57,000 on sodium dodecyl sulfate-polyacrylamide gel electrophoresis. |
T4 | 725-832 | Sentence | denotes | A single band, with enzyme activity, was observed in nondenaturing acrylamide gels containing Triton X-100. |
T5 | 833-892 | Sentence | denotes | Mn2+ was required for activity, and the pH optimum was 6.9. |
T6 | 893-981 | Sentence | denotes | Km values for UDP-GalNAc and globotriaosylceramide were 14 and 2.5 microM, respectively. |
T7 | 982-1180 | Sentence | denotes | Studies on substrate specificities indicate that the preferred substrates have the general structure Gal alpha 1-4Gal-OR in which the nature of the R moiety has relatively little effect on activity. |
T8 | 1181-1381 | Sentence | denotes | An antibody against the purified enzyme eliminated the activity of the enzyme, but did not neutralize the alpha-3-N-acetylgalactosaminyltransferase involved in the biosynthesis of Forssman glycolipid. |
T1 | 0-190 | Sentence | denotes | Purification and characterization of UDP-N-acetylgalactosamine: globotriaosylceramide beta-3-N-acetylgalactosaminyltransferase, a synthase of human blood group P antigen, from canine spleen. |
T2 | 191-561 | Sentence | denotes | A UDP-N-acetylgalactosamine:globotriaosylceramide beta-3-N-acetylgalactosaminyltransferase which catalyzes the conversion of human blood group Pk antigen into P antigen has been purified over 18,000-fold in 4% yield from a Triton X-100 extract of canine spleen microsomes by affinity chromatography on UDP-hexanolamine-Sepharose and globotriaosylceramide acid-Sepharose. |
T3 | 562-724 | Sentence | denotes | The purified enzyme migrates as two major bands with apparent molecular weights of 64,000 and 57,000 on sodium dodecyl sulfate-polyacrylamide gel electrophoresis. |
T4 | 725-832 | Sentence | denotes | A single band, with enzyme activity, was observed in nondenaturing acrylamide gels containing Triton X-100. |
T5 | 833-892 | Sentence | denotes | Mn2+ was required for activity, and the pH optimum was 6.9. |
T6 | 893-981 | Sentence | denotes | Km values for UDP-GalNAc and globotriaosylceramide were 14 and 2.5 microM, respectively. |
T7 | 982-1180 | Sentence | denotes | Studies on substrate specificities indicate that the preferred substrates have the general structure Gal alpha 1-4Gal-OR in which the nature of the R moiety has relatively little effect on activity. |
T8 | 1181-1381 | Sentence | denotes | An antibody against the purified enzyme eliminated the activity of the enzyme, but did not neutralize the alpha-3-N-acetylgalactosaminyltransferase involved in the biosynthesis of Forssman glycolipid. |
GlyCosmos6-Glycan-Motif-Structure
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 41-62 | https://glytoucan.org/Structures/Glycans/G27025MB | denotes | N-acetylgalactosamine |
T2 | 64-85 | https://glytoucan.org/Structures/Glycans/G00059MO | denotes | globotriaosylceramide |
T3 | 160-169 | https://glytoucan.org/Structures/Glycans/G00061MO | denotes | P antigen |
T4 | 334-344 | https://glytoucan.org/Structures/Glycans/G00059MO | denotes | Pk antigen |
T5 | 350-359 | https://glytoucan.org/Structures/Glycans/G00061MO | denotes | P antigen |
T6 | 524-545 | https://glytoucan.org/Structures/Glycans/G00059MO | denotes | globotriaosylceramide |
T7 | 922-943 | https://glytoucan.org/Structures/Glycans/G00059MO | denotes | globotriaosylceramide |
T8 | 1361-1380 | https://glytoucan.org/Structures/Glycans/G00064MO | denotes | Forssman glycolipid |
T9 | 1361-1380 | https://glytoucan.org/Structures/Glycans/G80062GG | denotes | Forssman glycolipid |
Glycosmos6-GlycoEpitope
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 334-344 | http://www.glycoepitope.jp/epitopes/EP0045 | denotes | Pk antigen |
T2 | 334-344 | http://www.glycoepitope.jp/epitopes/AN0211 | denotes | Pk antigen |
Glycosmos6-MAT
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 148-153 | http://purl.obolibrary.org/obo/MAT_0000083 | denotes | blood |
T2 | 148-153 | http://purl.obolibrary.org/obo/MAT_0000315 | denotes | blood |
T3 | 183-189 | http://purl.obolibrary.org/obo/MAT_0000085 | denotes | spleen |
T4 | 322-327 | http://purl.obolibrary.org/obo/MAT_0000083 | denotes | blood |
T5 | 322-327 | http://purl.obolibrary.org/obo/MAT_0000315 | denotes | blood |
T6 | 445-451 | http://purl.obolibrary.org/obo/MAT_0000085 | denotes | spleen |
glycogenes
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
PD-GlycoGenes20190927-B_T1 | 360-363 | https://acgg.asia/db/ggdb/info/gg135 | denotes | has |
PD-GlycoGenes20190927-B_T2 | 1139-1142 | https://acgg.asia/db/ggdb/info/gg135 | denotes | has |
Anatomy-MAT
Id | Subject | Object | Predicate | Lexical cue | mat_id |
---|---|---|---|---|---|
T1 | 148-153 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |
T3 | 183-189 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/MAT_0000085 |
T4 | 322-327 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |
T6 | 445-451 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/MAT_0000085 |
NCBITAXON
Id | Subject | Object | Predicate | Lexical cue | db_id |
---|---|---|---|---|---|
T1 | 142-147 | OrganismTaxon | denotes | human | 9606 |
T2 | 316-321 | OrganismTaxon | denotes | human | 9606 |
Glycosmos15-GlycoEpitope
Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
---|---|---|---|---|---|
T1 | 334-344 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Pk antigen | http://www.glycoepitope.jp/epitopes/EP0045|http://www.glycoepitope.jp/epitopes/AN0211 |
Anatomy-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T1 | 148-153 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
T2 | 176-182 | Body_part | denotes | canine | http://purl.obolibrary.org/obo/UBERON_0003674 |
T3 | 183-189 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/UBERON_0002106 |
T4 | 322-327 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
T5 | 438-444 | Body_part | denotes | canine | http://purl.obolibrary.org/obo/UBERON_0003674 |
T6 | 445-451 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/UBERON_0002106 |
Glycosmos15-CL
Id | Subject | Object | Predicate | Lexical cue | cl_id |
---|---|---|---|---|---|
T1 | 734-738 | Cell | denotes | band | http://purl.obolibrary.org/obo/CL:0000560 |