PubMed:37950443
Annnotations
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 0-7 | Glycan | denotes | Lewis a | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39023AU |
| T2 | 611-618 | Glycan | denotes | Lewis a | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39023AU |
| T3 | 620-627 | Glycan | denotes | Lewis b | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00048MO |
| T4 | 721-728 | Glycan | denotes | Lewis a | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39023AU |
| T5 | 751-758 | Glycan | denotes | Lewis a | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39023AU |
| T6 | 769-776 | Glycan | denotes | Lewis a | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39023AU |
| T7 | 784-791 | Glycan | denotes | Lewis a | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39023AU |
| T8 | 934-941 | Glycan | denotes | Lewis a | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39023AU |
| T9 | 1113-1120 | Glycan | denotes | Lewis a | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39023AU |
| T10 | 1125-1132 | Glycan | denotes | Lewis a | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39023AU |
| T11 | 1137-1144 | Glycan | denotes | Lewis a | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39023AU |
| T12 | 1341-1348 | Glycan | denotes | Lewis a | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39023AU |
| T13 | 1513-1520 | Glycan | denotes | Lewis a | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39023AU |
| T14 | 1652-1659 | Glycan | denotes | Lewis a | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39023AU |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 71-79 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T2 | 172-182 | Disease | denotes | SARS-CoV-2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T3 | 183-193 | Disease | denotes | infections | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T4 | 210-218 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T5 | 358-368 | Disease | denotes | SARS-CoV-2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T6 | 369-379 | Disease | denotes | infections | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T7 | 454-464 | Disease | denotes | SARS-CoV-2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T8 | 478-488 | Disease | denotes | SARS-CoV-2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T9 | 867-877 | Disease | denotes | SARS-CoV-2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T10 | 973-983 | Disease | denotes | SARS-CoV-2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T11 | 1213-1223 | Disease | denotes | SARS-CoV-2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T12 | 1237-1247 | Disease | denotes | SARS-CoV-2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T13 | 1405-1413 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T14 | 1559-1567 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T15 | 1708-1718 | Disease | denotes | SARS-CoV-2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T16 | 1767-1775 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 0-7 | Glycan | denotes | Lewis a | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39023AU |
| T2 | 611-618 | Glycan | denotes | Lewis a | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39023AU |
| T3 | 620-627 | Glycan | denotes | Lewis b | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00048MO |
| T4 | 721-728 | Glycan | denotes | Lewis a | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39023AU |
| T5 | 751-758 | Glycan | denotes | Lewis a | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39023AU |
| T6 | 769-776 | Glycan | denotes | Lewis a | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39023AU |
| T7 | 784-791 | Glycan | denotes | Lewis a | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39023AU |
| T8 | 934-941 | Glycan | denotes | Lewis a | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39023AU |
| T9 | 1113-1120 | Glycan | denotes | Lewis a | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39023AU |
| T10 | 1125-1132 | Glycan | denotes | Lewis a | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39023AU |
| T11 | 1137-1144 | Glycan | denotes | Lewis a | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39023AU |
| T12 | 1341-1348 | Glycan | denotes | Lewis a | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39023AU |
| T13 | 1513-1520 | Glycan | denotes | Lewis a | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39023AU |
| T14 | 1652-1659 | Glycan | denotes | Lewis a | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39023AU |
GlyCosmos-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 0-7 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis a | http://www.glycoepitope.jp/epitopes/EP0007 |
| T2 | 611-618 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis a | http://www.glycoepitope.jp/epitopes/EP0007 |
| T3 | 620-627 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis b | http://www.glycoepitope.jp/epitopes/EP0010 |
| T4 | 721-728 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis a | http://www.glycoepitope.jp/epitopes/EP0007 |
| T5 | 751-758 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis a | http://www.glycoepitope.jp/epitopes/EP0007 |
| T6 | 769-776 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis a | http://www.glycoepitope.jp/epitopes/EP0007 |
| T7 | 784-791 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis a | http://www.glycoepitope.jp/epitopes/EP0007 |
| T8 | 934-941 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis a | http://www.glycoepitope.jp/epitopes/EP0007 |
| T9 | 1113-1120 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis a | http://www.glycoepitope.jp/epitopes/EP0007 |
| T10 | 1125-1132 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis a | http://www.glycoepitope.jp/epitopes/EP0007 |
| T11 | 1137-1144 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis a | http://www.glycoepitope.jp/epitopes/EP0007 |
| T12 | 1341-1348 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis a | http://www.glycoepitope.jp/epitopes/EP0007 |
| T13 | 1513-1520 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis a | http://www.glycoepitope.jp/epitopes/EP0007 |
| T14 | 1652-1659 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis a | http://www.glycoepitope.jp/epitopes/EP0007 |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 17-22 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T2 | 290-295 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
GlyCosmos15-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 71-79 | Disease | denotes | COVID-19 | MONDO:0100096 |
| T2 | 172-182 | Disease | denotes | SARS-CoV-2 | MONDO:0100096 |
| T3 | 183-193 | Disease | denotes | infections | MONDO:0005550 |
| T4 | 210-218 | Disease | denotes | COVID-19 | MONDO:0100096 |
| T5 | 358-368 | Disease | denotes | SARS-CoV-2 | MONDO:0100096 |
| T6 | 369-379 | Disease | denotes | infections | MONDO:0005550 |
| T7 | 454-464 | Disease | denotes | SARS-CoV-2 | MONDO:0100096 |
| T8 | 478-488 | Disease | denotes | SARS-CoV-2 | MONDO:0100096 |
| T9 | 867-877 | Disease | denotes | SARS-CoV-2 | MONDO:0100096 |
| T10 | 973-983 | Disease | denotes | SARS-CoV-2 | MONDO:0100096 |
| T11 | 1213-1223 | Disease | denotes | SARS-CoV-2 | MONDO:0100096 |
| T12 | 1237-1247 | Disease | denotes | SARS-CoV-2 | MONDO:0100096 |
| T13 | 1405-1413 | Disease | denotes | COVID-19 | MONDO:0100096 |
| T14 | 1559-1567 | Disease | denotes | COVID-19 | MONDO:0100096 |
| T15 | 1708-1718 | Disease | denotes | SARS-CoV-2 | MONDO:0100096 |
| T16 | 1767-1775 | Disease | denotes | COVID-19 | MONDO:0100096 |
GlyCosmos15-Taxon
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 172-180 | Organism | denotes | SARS-CoV | 694009 |
| T2 | 358-366 | Organism | denotes | SARS-CoV | 694009 |
| T3 | 454-462 | Organism | denotes | SARS-CoV | 694009 |
| T4 | 478-486 | Organism | denotes | SARS-CoV | 694009 |
| T5 | 867-875 | Organism | denotes | SARS-CoV | 694009 |
| T6 | 973-981 | Organism | denotes | SARS-CoV | 694009 |
| T7 | 1213-1221 | Organism | denotes | SARS-CoV | 694009 |
| T8 | 1237-1245 | Organism | denotes | SARS-CoV | 694009 |
| T9 | 1708-1716 | Organism | denotes | SARS-CoV | 694009 |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-124 | Sentence | denotes | Lewis a-b- histo-blood group antigen phenotype is predictive of severe COVID-19 in the black South African population group. |
| T2 | 125-237 | Sentence | denotes | Several risk factors have been associated with SARS-CoV-2 infections and severity of COVID-19 disease it causes. |
| T3 | 238-408 | Sentence | denotes | This study investigated whether variations in histo-blood group antigen (HBGA) expression can predispose individuals to SARS-CoV-2 infections and severity of the disease. |
| T4 | 409-650 | Sentence | denotes | Nasopharyngeal swabs, randomly selected from SARS-CoV-2 positive and SARS-CoV-2 negative individuals, were tested for Lewis and H-type 1 HBGA phenotypes by ELISA using monoclonal antibodies specific to Lewis a, Lewis b and H type 1 antigens. |
| T5 | 651-857 | Sentence | denotes | The most common Lewis HBGA phenotype among all study participants was Lewis a-b+ (46%), followed by Lewis a-b- (24%), Lewis a+b- and Lewis a+b+ (15% each), while 55% of the study participants were H-type 1. |
| T6 | 858-1011 | Sentence | denotes | Although SARS-CoV-2 negative individuals had a lower likelihood of having a Lewis a-b- phenotype compared to their SARS-CoV-2 positives counterparts (OR: |
| T7 | 1012-1026 | Sentence | denotes | 0.53, 95% C.I: |
| T8 | 1027-1095 | Sentence | denotes | 0.255-1.113), it did not reach statistical significance (P = 0.055). |
| T9 | 1096-1269 | Sentence | denotes | The frequency of Lewis a+b+, Lewis a+B-, Lewis a-b+, H type 1 positive and H type 1 negative were consistent between SARS-CoV-2 positive and SARS-CoV-2 negative individuals. |
| T10 | 1270-1427 | Sentence | denotes | When stratified according to severity of the disease, individuals with Lewis a+b- phenotype had a higher likelihood of developing mild COVID-19 symptoms (OR: |
| T11 | 1428-1581 | Sentence | denotes | 3.27, 95% CI; 0.9604-11.1), but was not statistically significant (P = 0.055), while Lewis a-b- phenotype was predictive of severe COVID-19 symptoms (OR: |
| T12 | 1582-1594 | Sentence | denotes | 4.3, 95% CI: |
| T13 | 1595-1619 | Sentence | denotes | 1.274-14.81), P = 0.016. |
| T14 | 1620-1776 | Sentence | denotes | In conclusion, individuals with Lewis a-b- phenotype were less likely to be infected by SARS-CoV-2, but when infected, they were at risk of severe COVID-19. |
GlyCosmos15-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 0-7 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis a | http://www.glycoepitope.jp/epitopes/EP0007 |
| T2 | 611-618 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis a | http://www.glycoepitope.jp/epitopes/EP0007 |
| T3 | 620-627 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis b | http://www.glycoepitope.jp/epitopes/EP0010 |
| T4 | 721-728 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis a | http://www.glycoepitope.jp/epitopes/EP0007 |
| T5 | 751-758 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis a | http://www.glycoepitope.jp/epitopes/EP0007 |
| T6 | 769-776 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis a | http://www.glycoepitope.jp/epitopes/EP0007 |
| T7 | 784-791 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis a | http://www.glycoepitope.jp/epitopes/EP0007 |
| T8 | 934-941 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis a | http://www.glycoepitope.jp/epitopes/EP0007 |
| T9 | 1113-1120 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis a | http://www.glycoepitope.jp/epitopes/EP0007 |
| T10 | 1125-1132 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis a | http://www.glycoepitope.jp/epitopes/EP0007 |
| T11 | 1137-1144 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis a | http://www.glycoepitope.jp/epitopes/EP0007 |
| T12 | 1341-1348 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis a | http://www.glycoepitope.jp/epitopes/EP0007 |
| T13 | 1513-1520 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis a | http://www.glycoepitope.jp/epitopes/EP0007 |
| T14 | 1652-1659 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis a | http://www.glycoepitope.jp/epitopes/EP0007 |
GlyCosmos15-FMA
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 17-22 | Body_part | denotes | blood | FMA:9670 |
| T2 | 290-295 | Body_part | denotes | blood | FMA:9670 |
GlyCosmos15-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 17-22 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000315 |
| T2 | 290-295 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000315 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 172-180 | OrganismTaxon | denotes | SARS-CoV | 694009 |
| T2 | 358-366 | OrganismTaxon | denotes | SARS-CoV | 694009 |
| T3 | 454-462 | OrganismTaxon | denotes | SARS-CoV | 694009 |
| T4 | 478-486 | OrganismTaxon | denotes | SARS-CoV | 694009 |
| T5 | 867-875 | OrganismTaxon | denotes | SARS-CoV | 694009 |
| T6 | 973-981 | OrganismTaxon | denotes | SARS-CoV | 694009 |
| T7 | 1213-1221 | OrganismTaxon | denotes | SARS-CoV | 694009 |
| T8 | 1237-1245 | OrganismTaxon | denotes | SARS-CoV | 694009 |
| T9 | 1708-1716 | OrganismTaxon | denotes | SARS-CoV | 694009 |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 17-22 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |
| T3 | 290-295 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 17-22 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T2 | 290-295 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |