PubMed:36240590 JSONTXT

{"project":"mondo_disease","denotations":[{"id":"T1","span":{"begin":323,"end":326},"obj":"Disease"},{"id":"T2","span":{"begin":456,"end":459},"obj":"Disease"},{"id":"T3","span":{"begin":584,"end":587},"obj":"Disease"},{"id":"T4","span":{"begin":792,"end":795},"obj":"Disease"},{"id":"T5","span":{"begin":843,"end":846},"obj":"Disease"},{"id":"T6","span":{"begin":970,"end":973},"obj":"Disease"},{"id":"T7","span":{"begin":1083,"end":1089},"obj":"Disease"},{"id":"T8","span":{"begin":1147,"end":1153},"obj":"Disease"}],"attributes":[{"id":"A1","pred":"mondo_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/MONDO_0009799"},{"id":"A2","pred":"mondo_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/MONDO_0009799"},{"id":"A3","pred":"mondo_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/MONDO_0009799"},{"id":"A4","pred":"mondo_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/MONDO_0009799"},{"id":"A5","pred":"mondo_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/MONDO_0009799"},{"id":"A6","pred":"mondo_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/MONDO_0009799"},{"id":"A7","pred":"mondo_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/MONDO_0021178"},{"id":"A8","pred":"mondo_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/MONDO_0021178"}],"text":"Chemical structure and protective effect against alcoholic kidney and heart damages of a novel polysaccharide from Piperis Dahongpao.\nIn this manuscript, the polysaccharide isolated from Piperis Dahongpao was extracted with the method of water-extraction and alcohol-precipitation. Besides, the homogeneous polysaccharide (PDP-1) with an MW of 2.47 × 103 KDa was purified with the Sephadex G-150 column. The monosaccharide composition analysis showed that PDP-1 consisted of Man, Glc and Gal in a ratio of 1.678:1.784:1, respectively. Besides, the methylation analysis indicated that PDP-1 was composed of six sugar alcohol derivatives, which were →4，6)-D-Galp-(1→, →4)-D-Galp-(1→, →4)-D -Manp-(1→, →4)-D-Glcp-(1→, →6)-D -Glcp-(1→ and D-Glcp-(1 → . Otherwise, the microscopic conformation of PDP-1 was flat, dense and porous. In addition, the PDP-1 had a strong scavenging ability for DPPH free radicals, Hydroxyl free radicals and ABTS free radicals. At the same time, PDP-1 could effectively decrease the peroxidation process of kidney and heart in mice with acute alcoholic liver injury, improve its antioxidant capacity, and protect the organ injury caused by alcohol to a certain extent. Therefore, the results of this manuscript showed that Piperis Dahongpao polysaccharides have antioxidant potential, which lays a theoretical foundation for the research of Piperis Dahongpa polysaccharides in medicine."}

{"project":"Glycosmos6-MAT","denotations":[{"id":"T1","span":{"begin":59,"end":65},"obj":"http://purl.obolibrary.org/obo/MAT_0000119"},{"id":"T2","span":{"begin":70,"end":75},"obj":"http://purl.obolibrary.org/obo/MAT_0000036"},{"id":"T3","span":{"begin":1031,"end":1037},"obj":"http://purl.obolibrary.org/obo/MAT_0000119"},{"id":"T4","span":{"begin":1042,"end":1047},"obj":"http://purl.obolibrary.org/obo/MAT_0000036"},{"id":"T5","span":{"begin":1077,"end":1082},"obj":"http://purl.obolibrary.org/obo/MAT_0000097"}],"text":"Chemical structure and protective effect against alcoholic kidney and heart damages of a novel polysaccharide from Piperis Dahongpao.\nIn this manuscript, the polysaccharide isolated from Piperis Dahongpao was extracted with the method of water-extraction and alcohol-precipitation. Besides, the homogeneous polysaccharide (PDP-1) with an MW of 2.47 × 103 KDa was purified with the Sephadex G-150 column. The monosaccharide composition analysis showed that PDP-1 consisted of Man, Glc and Gal in a ratio of 1.678:1.784:1, respectively. Besides, the methylation analysis indicated that PDP-1 was composed of six sugar alcohol derivatives, which were →4，6)-D-Galp-(1→, →4)-D-Galp-(1→, →4)-D -Manp-(1→, →4)-D-Glcp-(1→, →6)-D -Glcp-(1→ and D-Glcp-(1 → . Otherwise, the microscopic conformation of PDP-1 was flat, dense and porous. In addition, the PDP-1 had a strong scavenging ability for DPPH free radicals, Hydroxyl free radicals and ABTS free radicals. At the same time, PDP-1 could effectively decrease the peroxidation process of kidney and heart in mice with acute alcoholic liver injury, improve its antioxidant capacity, and protect the organ injury caused by alcohol to a certain extent. Therefore, the results of this manuscript showed that Piperis Dahongpao polysaccharides have antioxidant potential, which lays a theoretical foundation for the research of Piperis Dahongpa polysaccharides in medicine."}

{"project":"NCBITAXON","denotations":[{"id":"T1","span":{"begin":1051,"end":1055},"obj":"OrganismTaxon"}],"attributes":[{"id":"A1","pred":"db_id","subj":"T1","obj":"10088"}],"text":"Chemical structure and protective effect against alcoholic kidney and heart damages of a novel polysaccharide from Piperis Dahongpao.\nIn this manuscript, the polysaccharide isolated from Piperis Dahongpao was extracted with the method of water-extraction and alcohol-precipitation. Besides, the homogeneous polysaccharide (PDP-1) with an MW of 2.47 × 103 KDa was purified with the Sephadex G-150 column. The monosaccharide composition analysis showed that PDP-1 consisted of Man, Glc and Gal in a ratio of 1.678:1.784:1, respectively. Besides, the methylation analysis indicated that PDP-1 was composed of six sugar alcohol derivatives, which were →4，6)-D-Galp-(1→, →4)-D-Galp-(1→, →4)-D -Manp-(1→, →4)-D-Glcp-(1→, →6)-D -Glcp-(1→ and D-Glcp-(1 → . Otherwise, the microscopic conformation of PDP-1 was flat, dense and porous. In addition, the PDP-1 had a strong scavenging ability for DPPH free radicals, Hydroxyl free radicals and ABTS free radicals. At the same time, PDP-1 could effectively decrease the peroxidation process of kidney and heart in mice with acute alcoholic liver injury, improve its antioxidant capacity, and protect the organ injury caused by alcohol to a certain extent. Therefore, the results of this manuscript showed that Piperis Dahongpao polysaccharides have antioxidant potential, which lays a theoretical foundation for the research of Piperis Dahongpa polysaccharides in medicine."}

{"project":"Anatomy-UBERON","denotations":[{"id":"T1","span":{"begin":59,"end":65},"obj":"Body_part"},{"id":"T2","span":{"begin":70,"end":75},"obj":"Body_part"},{"id":"T6","span":{"begin":1031,"end":1037},"obj":"Body_part"},{"id":"T7","span":{"begin":1042,"end":1047},"obj":"Body_part"},{"id":"T11","span":{"begin":1077,"end":1082},"obj":"Body_part"},{"id":"T12","span":{"begin":1141,"end":1146},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"uberon_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/UBERON_0002113"},{"id":"A2","pred":"uberon_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/UBERON_0000948"},{"id":"A3","pred":"uberon_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/UBERON_0007100"},{"id":"A4","pred":"uberon_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/UBERON_0015228"},{"id":"A5","pred":"uberon_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/UBERON_0015230"},{"id":"A6","pred":"uberon_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/UBERON_0002113"},{"id":"A7","pred":"uberon_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/UBERON_0000948"},{"id":"A8","pred":"uberon_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/UBERON_0007100"},{"id":"A9","pred":"uberon_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/UBERON_0015228"},{"id":"A10","pred":"uberon_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/UBERON_0015230"},{"id":"A11","pred":"uberon_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/UBERON_0002107"},{"id":"A12","pred":"uberon_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/UBERON_0000062"},{"id":"A13","pred":"uberon_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/UBERON_0003103"}],"text":"Chemical structure and protective effect against alcoholic kidney and heart damages of a novel polysaccharide from Piperis Dahongpao.\nIn this manuscript, the polysaccharide isolated from Piperis Dahongpao was extracted with the method of water-extraction and alcohol-precipitation. Besides, the homogeneous polysaccharide (PDP-1) with an MW of 2.47 × 103 KDa was purified with the Sephadex G-150 column. The monosaccharide composition analysis showed that PDP-1 consisted of Man, Glc and Gal in a ratio of 1.678:1.784:1, respectively. Besides, the methylation analysis indicated that PDP-1 was composed of six sugar alcohol derivatives, which were →4，6)-D-Galp-(1→, →4)-D-Galp-(1→, →4)-D -Manp-(1→, →4)-D-Glcp-(1→, →6)-D -Glcp-(1→ and D-Glcp-(1 → . Otherwise, the microscopic conformation of PDP-1 was flat, dense and porous. In addition, the PDP-1 had a strong scavenging ability for DPPH free radicals, Hydroxyl free radicals and ABTS free radicals. At the same time, PDP-1 could effectively decrease the peroxidation process of kidney and heart in mice with acute alcoholic liver injury, improve its antioxidant capacity, and protect the organ injury caused by alcohol to a certain extent. Therefore, the results of this manuscript showed that Piperis Dahongpao polysaccharides have antioxidant potential, which lays a theoretical foundation for the research of Piperis Dahongpa polysaccharides in medicine."}

{"project":"Anatomy-MAT","denotations":[{"id":"T1","span":{"begin":59,"end":65},"obj":"Body_part"},{"id":"T2","span":{"begin":70,"end":75},"obj":"Body_part"},{"id":"T3","span":{"begin":1031,"end":1037},"obj":"Body_part"},{"id":"T4","span":{"begin":1042,"end":1047},"obj":"Body_part"},{"id":"T5","span":{"begin":1077,"end":1082},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"mat_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/MAT_0000119"},{"id":"A2","pred":"mat_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/MAT_0000036"},{"id":"A3","pred":"mat_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/MAT_0000119"},{"id":"A4","pred":"mat_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/MAT_0000036"},{"id":"A5","pred":"mat_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/MAT_0000097"}],"text":"Chemical structure and protective effect against alcoholic kidney and heart damages of a novel polysaccharide from Piperis Dahongpao.\nIn this manuscript, the polysaccharide isolated from Piperis Dahongpao was extracted with the method of water-extraction and alcohol-precipitation. Besides, the homogeneous polysaccharide (PDP-1) with an MW of 2.47 × 103 KDa was purified with the Sephadex G-150 column. The monosaccharide composition analysis showed that PDP-1 consisted of Man, Glc and Gal in a ratio of 1.678:1.784:1, respectively. Besides, the methylation analysis indicated that PDP-1 was composed of six sugar alcohol derivatives, which were →4，6)-D-Galp-(1→, →4)-D-Galp-(1→, →4)-D -Manp-(1→, →4)-D-Glcp-(1→, →6)-D -Glcp-(1→ and D-Glcp-(1 → . Otherwise, the microscopic conformation of PDP-1 was flat, dense and porous. In addition, the PDP-1 had a strong scavenging ability for DPPH free radicals, Hydroxyl free radicals and ABTS free radicals. At the same time, PDP-1 could effectively decrease the peroxidation process of kidney and heart in mice with acute alcoholic liver injury, improve its antioxidant capacity, and protect the organ injury caused by alcohol to a certain extent. Therefore, the results of this manuscript showed that Piperis Dahongpao polysaccharides have antioxidant potential, which lays a theoretical foundation for the research of Piperis Dahongpa polysaccharides in medicine."}