PubMed:35260716
Annnotations
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 50-58 | Disease | denotes | pancreas | http://purl.obolibrary.org/obo/MONDO_0021040 |
| T2 | 218-236 | Disease | denotes | metabolic diseases | http://purl.obolibrary.org/obo/MONDO_0005066 |
| T3 | 659-667 | Disease | denotes | pancreas | http://purl.obolibrary.org/obo/MONDO_0021040 |
| T4 | 991-999 | Disease | denotes | pancreas | http://purl.obolibrary.org/obo/MONDO_0021040 |
| T5 | 1332-1351 | Disease | denotes | metabolic disorders | http://purl.obolibrary.org/obo/MONDO_0005066 |
| T6 | 1420-1428 | Disease | denotes | pancreas | http://purl.obolibrary.org/obo/MONDO_0021040 |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 45-48 | Body_part | denotes | gut | http://purl.obolibrary.org/obo/MAT_0000043 |
| T2 | 50-58 | Body_part | denotes | pancreas | http://purl.obolibrary.org/obo/MAT_0000075 |
| T3 | 63-69 | Body_part | denotes | thymus | http://purl.obolibrary.org/obo/MAT_0000080 |
| T4 | 611-628 | Body_part | denotes | endocrine systems | http://purl.obolibrary.org/obo/MAT_0000021 |
| T5 | 659-667 | Body_part | denotes | pancreas | http://purl.obolibrary.org/obo/MAT_0000075 |
| T6 | 669-678 | Body_part | denotes | intestine | http://purl.obolibrary.org/obo/MAT_0000043 |
| T7 | 683-689 | Body_part | denotes | thymus | http://purl.obolibrary.org/obo/MAT_0000080 |
| T8 | 738-755 | Body_part | denotes | pancreatic islets | http://purl.obolibrary.org/obo/MAT_0000076 |
| T9 | 776-786 | Body_part | denotes | intestinal | http://purl.obolibrary.org/obo/MAT_0000043 |
| T10 | 810-816 | Body_part | denotes | thymus | http://purl.obolibrary.org/obo/MAT_0000080 |
| T11 | 991-999 | Body_part | denotes | pancreas | http://purl.obolibrary.org/obo/MAT_0000075 |
| T12 | 1026-1036 | Body_part | denotes | intestinal | http://purl.obolibrary.org/obo/MAT_0000043 |
| T13 | 1054-1064 | Body_part | denotes | intestinal | http://purl.obolibrary.org/obo/MAT_0000043 |
| T14 | 1370-1380 | Body_part | denotes | intestinal | http://purl.obolibrary.org/obo/MAT_0000043 |
| T15 | 1420-1428 | Body_part | denotes | pancreas | http://purl.obolibrary.org/obo/MAT_0000075 |
| T16 | 1445-1451 | Body_part | denotes | thymus | http://purl.obolibrary.org/obo/MAT_0000080 |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 315-322 | Glycan | denotes | lactose | https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE |
GlyCosmos15-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 50-58 | Disease | denotes | pancreas | http://purl.obolibrary.org/obo/MONDO_0021040 |
| T2 | 218-236 | Disease | denotes | metabolic diseases | http://purl.obolibrary.org/obo/MONDO_0005066 |
| T3 | 659-667 | Disease | denotes | pancreas | http://purl.obolibrary.org/obo/MONDO_0021040 |
| T4 | 991-999 | Disease | denotes | pancreas | http://purl.obolibrary.org/obo/MONDO_0021040 |
| T5 | 1332-1351 | Disease | denotes | metabolic disorders | http://purl.obolibrary.org/obo/MONDO_0005066 |
| T6 | 1420-1428 | Disease | denotes | pancreas | http://purl.obolibrary.org/obo/MONDO_0021040 |
GlyCosmos15-NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 63-69 | OrganismTaxon | denotes | thymus | 49990 |
| T2 | 81-85 | OrganismTaxon | denotes | rats | 10114|10116 |
| T4 | 545-549 | OrganismTaxon | denotes | rats | 10114|10116 |
| T6 | 683-689 | OrganismTaxon | denotes | thymus | 49990 |
| T7 | 810-816 | OrganismTaxon | denotes | thymus | 49990 |
| T8 | 1445-1451 | OrganismTaxon | denotes | thymus | 49990 |
GlyCosmos15-CL
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 1142-1152 | Cell | denotes | tuft cells | http://purl.obolibrary.org/obo/CL:0002204 |
| T2 | 1220-1227 | Cell | denotes | T cells | http://purl.obolibrary.org/obo/CL:0000084 |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 45-48 | Body_part | denotes | gut | http://purl.obolibrary.org/obo/UBERON_0001007|http://purl.obolibrary.org/obo/UBERON_0001555|http://purl.obolibrary.org/obo/UBERON_0004907 |
| T4 | 50-58 | Body_part | denotes | pancreas | http://purl.obolibrary.org/obo/UBERON_0001264|http://purl.obolibrary.org/obo/UBERON_3011040 |
| T6 | 63-69 | Body_part | denotes | thymus | http://purl.obolibrary.org/obo/UBERON_0002370 |
| T7 | 99-103 | Body_part | denotes | milk | http://purl.obolibrary.org/obo/UBERON_0001913 |
| T8 | 267-271 | Body_part | denotes | milk | http://purl.obolibrary.org/obo/UBERON_0001913 |
| T9 | 335-339 | Body_part | denotes | milk | http://purl.obolibrary.org/obo/UBERON_0001913 |
| T10 | 611-628 | Body_part | denotes | endocrine systems | http://purl.obolibrary.org/obo/UBERON_0000949 |
| T11 | 659-667 | Body_part | denotes | pancreas | http://purl.obolibrary.org/obo/UBERON_0001264|http://purl.obolibrary.org/obo/UBERON_3011040 |
| T13 | 669-678 | Body_part | denotes | intestine | http://purl.obolibrary.org/obo/UBERON_0000160 |
| T14 | 683-689 | Body_part | denotes | thymus | http://purl.obolibrary.org/obo/UBERON_0002370 |
| T15 | 738-755 | Body_part | denotes | pancreatic islets | http://purl.obolibrary.org/obo/UBERON_0000006 |
| T16 | 776-793 | Body_part | denotes | intestinal mucosa | http://purl.obolibrary.org/obo/UBERON_0001242 |
| T17 | 810-816 | Body_part | denotes | thymus | http://purl.obolibrary.org/obo/UBERON_0002370 |
| T18 | 981-999 | Body_part | denotes | endocrine pancreas | http://purl.obolibrary.org/obo/UBERON_0000016 |
| T19 | 1026-1043 | Body_part | denotes | intestinal mucosa | http://purl.obolibrary.org/obo/UBERON_0001242 |
| T20 | 1125-1137 | Body_part | denotes | nerve fibres | http://purl.obolibrary.org/obo/UBERON_0006134 |
| T21 | 1142-1152 | Body_part | denotes | tuft cells | http://purl.obolibrary.org/obo/CL_0002204 |
| T22 | 1420-1428 | Body_part | denotes | pancreas | http://purl.obolibrary.org/obo/UBERON_0001264|http://purl.obolibrary.org/obo/UBERON_3011040 |
| T24 | 1445-1451 | Body_part | denotes | thymus | http://purl.obolibrary.org/obo/UBERON_0002370 |
GlyCosmos15-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 45-48 | Body_part | denotes | gut | http://purl.obolibrary.org/obo/MAT_0000043 |
| T2 | 50-58 | Body_part | denotes | pancreas | http://purl.obolibrary.org/obo/MAT_0000075 |
| T3 | 63-69 | Body_part | denotes | thymus | http://purl.obolibrary.org/obo/MAT_0000080 |
| T4 | 611-628 | Body_part | denotes | endocrine systems | http://purl.obolibrary.org/obo/MAT_0000021 |
| T5 | 659-667 | Body_part | denotes | pancreas | http://purl.obolibrary.org/obo/MAT_0000075 |
| T6 | 669-678 | Body_part | denotes | intestine | http://purl.obolibrary.org/obo/MAT_0000043 |
| T7 | 683-689 | Body_part | denotes | thymus | http://purl.obolibrary.org/obo/MAT_0000080 |
| T8 | 738-755 | Body_part | denotes | pancreatic islets | http://purl.obolibrary.org/obo/MAT_0000076 |
| T9 | 776-786 | Body_part | denotes | intestinal | http://purl.obolibrary.org/obo/MAT_0000043 |
| T10 | 810-816 | Body_part | denotes | thymus | http://purl.obolibrary.org/obo/MAT_0000080 |
| T11 | 991-999 | Body_part | denotes | pancreas | http://purl.obolibrary.org/obo/MAT_0000075 |
| T12 | 1026-1036 | Body_part | denotes | intestinal | http://purl.obolibrary.org/obo/MAT_0000043 |
| T13 | 1054-1064 | Body_part | denotes | intestinal | http://purl.obolibrary.org/obo/MAT_0000043 |
| T14 | 1370-1380 | Body_part | denotes | intestinal | http://purl.obolibrary.org/obo/MAT_0000043 |
| T15 | 1420-1428 | Body_part | denotes | pancreas | http://purl.obolibrary.org/obo/MAT_0000075 |
| T16 | 1445-1451 | Body_part | denotes | thymus | http://purl.obolibrary.org/obo/MAT_0000080 |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-137 | Sentence | denotes | Structural and immunoendocrine remodeling in gut, pancreas and thymus in weaning rats fed powdered milk diets rich in Maillard reactants. |
| T2 | 138-237 | Sentence | denotes | Western diet is extending worldwide and suspected to be associated with various metabolic diseases. |
| T3 | 238-398 | Sentence | denotes | Many food products have skim milk powder added to it and, during processing, lactose reacts with milk proteins and Maillard reaction products (MRPs) are formed. |
| T4 | 399-514 | Sentence | denotes | Dietary MRPs are suggested risk factors for metabolic dysregulation, but the mechanisms behind are still enigmatic. |
| T5 | 515-629 | Sentence | denotes | Here we describe that weaning rats fed diets rich in MRPs are affected in both their immune and endocrine systems. |
| T6 | 630-733 | Sentence | denotes | Marked structural changes in pancreas, intestine and thymus are noted already after 1 week of exposure. |
| T7 | 734-858 | Sentence | denotes | The pancreatic islets become sparser, the intestinal mucosa is thinner, and thymus displays increased apoptosis and atrophy. |
| T8 | 859-1044 | Sentence | denotes | Glucagon- like peptide-1 (GLP-1) seems to play a key role in that the number of GLP-1 expressing cells is up-regulated in endocrine pancreas but down-regulated in the intestinal mucosa. |
| T9 | 1045-1289 | Sentence | denotes | Further, intestinal GLP-1-immunoreactive cells are juxta positioned not only to nerve fibres and tuft cells, as previously described, but also to intraepithelial CD3 positive T cells, rendering them a strategic location in metabolic regulation. |
| T10 | 1290-1460 | Sentence | denotes | Our results suggest dietary MRPs to cause metabolic disorders, dysregulation of intestinal GLP-1- immunoreactive cells, arrest in pancreas development and thymus atrophy. |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 315-322 | Glycan | denotes | lactose | https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 63-69 | OrganismTaxon | denotes | thymus | 49990 |
| T2 | 81-85 | OrganismTaxon | denotes | rats | 10114|10116 |
| T4 | 545-549 | OrganismTaxon | denotes | rats | 10114|10116 |
| T6 | 683-689 | OrganismTaxon | denotes | thymus | 49990 |
| T7 | 810-816 | OrganismTaxon | denotes | thymus | 49990 |
| T8 | 1445-1451 | OrganismTaxon | denotes | thymus | 49990 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 45-48 | Body_part | denotes | gut | http://purl.obolibrary.org/obo/UBERON_0001007|http://purl.obolibrary.org/obo/UBERON_0001555|http://purl.obolibrary.org/obo/UBERON_0004907 |
| T4 | 50-58 | Body_part | denotes | pancreas | http://purl.obolibrary.org/obo/UBERON_0001264|http://purl.obolibrary.org/obo/UBERON_3011040 |
| T6 | 63-69 | Body_part | denotes | thymus | http://purl.obolibrary.org/obo/UBERON_0002370 |
| T7 | 99-103 | Body_part | denotes | milk | http://purl.obolibrary.org/obo/UBERON_0001913 |
| T8 | 267-271 | Body_part | denotes | milk | http://purl.obolibrary.org/obo/UBERON_0001913 |
| T9 | 335-339 | Body_part | denotes | milk | http://purl.obolibrary.org/obo/UBERON_0001913 |
| T10 | 611-628 | Body_part | denotes | endocrine systems | http://purl.obolibrary.org/obo/UBERON_0000949 |
| T11 | 659-667 | Body_part | denotes | pancreas | http://purl.obolibrary.org/obo/UBERON_0001264|http://purl.obolibrary.org/obo/UBERON_3011040 |
| T13 | 669-678 | Body_part | denotes | intestine | http://purl.obolibrary.org/obo/UBERON_0000160 |
| T14 | 683-689 | Body_part | denotes | thymus | http://purl.obolibrary.org/obo/UBERON_0002370 |
| T15 | 738-755 | Body_part | denotes | pancreatic islets | http://purl.obolibrary.org/obo/UBERON_0000006 |
| T16 | 776-793 | Body_part | denotes | intestinal mucosa | http://purl.obolibrary.org/obo/UBERON_0001242 |
| T17 | 810-816 | Body_part | denotes | thymus | http://purl.obolibrary.org/obo/UBERON_0002370 |
| T18 | 981-999 | Body_part | denotes | endocrine pancreas | http://purl.obolibrary.org/obo/UBERON_0000016 |
| T19 | 1026-1043 | Body_part | denotes | intestinal mucosa | http://purl.obolibrary.org/obo/UBERON_0001242 |
| T20 | 1125-1137 | Body_part | denotes | nerve fibres | http://purl.obolibrary.org/obo/UBERON_0006134 |
| T21 | 1142-1152 | Body_part | denotes | tuft cells | http://purl.obolibrary.org/obo/CL_0002204 |
| T22 | 1420-1428 | Body_part | denotes | pancreas | http://purl.obolibrary.org/obo/UBERON_0001264|http://purl.obolibrary.org/obo/UBERON_3011040 |
| T24 | 1445-1451 | Body_part | denotes | thymus | http://purl.obolibrary.org/obo/UBERON_0002370 |
CL-cell
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 1142-1152 | Cell | denotes | tuft cells | http://purl.obolibrary.org/obo/CL:0002204 |
| T2 | 1220-1227 | Cell | denotes | T cells | http://purl.obolibrary.org/obo/CL:0000084 |