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PubMed:34161143 JSONTXT

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Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-121 Sentence denotes Manual Acupuncture Plus Usual Care Versus Usual Care Alone in the Treatment of Endometriosis-Related Chronic Pelvic Pain:
T2 122-164 Sentence denotes A Randomized Controlled Feasibility Study.
T3 165-175 Sentence denotes Objective:
T4 176-301 Sentence denotes To determine the acceptability and feasibility of acupuncture for the treatment of endometriosis-related chronic pelvic pain.
T5 302-309 Sentence denotes Design:
T6 310-365 Sentence denotes A prospective, randomized controlled feasibility study.
T7 366-374 Sentence denotes Setting:
T8 375-415 Sentence denotes Outpatient setting in Sydney, Australia.
T9 416-425 Sentence denotes Subjects:
T10 426-611 Sentence denotes Participants who were aged 18-45 years, had a confirmed laparoscopic diagnosis of endometriosis in the past 5 years, and had regular menstrual periods and mean pelvic pain scores ≥4/10.
T11 612-626 Sentence denotes Interventions:
T12 627-809 Sentence denotes Sixteen acupuncture treatments delivered by registered acupuncturists using a standardized point protocol over 8 weeks, twice per week plus usual care compared with usual care alone.
T13 810-827 Sentence denotes Outcome measures:
T14 828-929 Sentence denotes Primary outcome measures were feasibility, safety, and acceptability of the acupuncture intervention.
T15 930-1203 Sentence denotes Secondary outcomes were changes in self-reported pelvic pain scores, changes in quality of life as measured by the Endometriosis Health Profile (EHP-30), changes in descending pain modulation, and changes in systemic inflammation (plasma interleukin [IL-6] concentrations).
T16 1204-1212 Sentence denotes Results:
T17 1213-1310 Sentence denotes Twenty-nine participants were eligible to participate, with 19 participants completing the trial.
T18 1311-1440 Sentence denotes There was unequal withdrawals between groups; the acupuncture group had a withdrawal rate of 14% compared with 53% in usual care.
T19 1441-1496 Sentence denotes Adverse events were uncommon (6.7%) and generally mild.
T20 1497-1682 Sentence denotes A 1.9 point decrease in median nonmenstrual pain scores and a 2.0 decrease in median menstrual pain scores between baseline and end of trial were observed in the acupuncture group only.
T21 1683-1796 Sentence denotes Improvements in all domains of the EHP-30 were seen in the acupuncture group, with no changes seen in usual care.
T22 1797-1899 Sentence denotes There was no difference between baseline and end of treatment in IL-6 concentrations for either group.
T23 1900-1912 Sentence denotes Conclusions:
T24 1913-2084 Sentence denotes Acupuncture was an acceptable, well-tolerated treatment and it may reduce pelvic pain and improve quality of life; however, usual care was not an acceptable control group.
T25 2085-2140 Sentence denotes Trial Registration: anzctr.org.au: ACTRN12617000053325.
T26 2141-2183 Sentence denotes Prospectively registered January 11, 2017.
T1 0-121 Sentence denotes Manual Acupuncture Plus Usual Care Versus Usual Care Alone in the Treatment of Endometriosis-Related Chronic Pelvic Pain:
T2 122-164 Sentence denotes A Randomized Controlled Feasibility Study.
T3 165-175 Sentence denotes Objective:
T4 176-301 Sentence denotes To determine the acceptability and feasibility of acupuncture for the treatment of endometriosis-related chronic pelvic pain.
T5 302-309 Sentence denotes Design:
T6 310-365 Sentence denotes A prospective, randomized controlled feasibility study.
T7 366-374 Sentence denotes Setting:
T8 375-415 Sentence denotes Outpatient setting in Sydney, Australia.
T9 416-425 Sentence denotes Subjects:
T10 426-611 Sentence denotes Participants who were aged 18-45 years, had a confirmed laparoscopic diagnosis of endometriosis in the past 5 years, and had regular menstrual periods and mean pelvic pain scores ≥4/10.
T11 612-626 Sentence denotes Interventions:
T12 627-809 Sentence denotes Sixteen acupuncture treatments delivered by registered acupuncturists using a standardized point protocol over 8 weeks, twice per week plus usual care compared with usual care alone.
T13 810-827 Sentence denotes Outcome measures:
T14 828-929 Sentence denotes Primary outcome measures were feasibility, safety, and acceptability of the acupuncture intervention.
T15 930-1203 Sentence denotes Secondary outcomes were changes in self-reported pelvic pain scores, changes in quality of life as measured by the Endometriosis Health Profile (EHP-30), changes in descending pain modulation, and changes in systemic inflammation (plasma interleukin [IL-6] concentrations).
T16 1204-1212 Sentence denotes Results:
T17 1213-1310 Sentence denotes Twenty-nine participants were eligible to participate, with 19 participants completing the trial.
T18 1311-1440 Sentence denotes There was unequal withdrawals between groups; the acupuncture group had a withdrawal rate of 14% compared with 53% in usual care.
T19 1441-1496 Sentence denotes Adverse events were uncommon (6.7%) and generally mild.
T20 1497-1682 Sentence denotes A 1.9 point decrease in median nonmenstrual pain scores and a 2.0 decrease in median menstrual pain scores between baseline and end of trial were observed in the acupuncture group only.
T21 1683-1796 Sentence denotes Improvements in all domains of the EHP-30 were seen in the acupuncture group, with no changes seen in usual care.
T22 1797-1899 Sentence denotes There was no difference between baseline and end of treatment in IL-6 concentrations for either group.
T23 1900-1912 Sentence denotes Conclusions:
T24 1913-2084 Sentence denotes Acupuncture was an acceptable, well-tolerated treatment and it may reduce pelvic pain and improve quality of life; however, usual care was not an acceptable control group.
T25 2085-2140 Sentence denotes Trial Registration: anzctr.org.au: ACTRN12617000053325.
T26 2141-2183 Sentence denotes Prospectively registered January 11, 2017.