PubMed:33446900
Annnotations
Inflammaging
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-93 | Sentence | denotes | Symptoms of anxiety/depression is associated with more aggressive inflammatory bowel disease. |
| T2 | 94-232 | Sentence | denotes | Studies have demonstrated that inflammatory bowel disease (IBD) patients are at an increased risk of developing anxiety and/or depression. |
| T3 | 233-357 | Sentence | denotes | IBD patients with depression/anxiety have higher rates of hospitalization and increased disease severity than those without. |
| T4 | 358-461 | Sentence | denotes | So far, there is a paucity of data concerning the impact of anxiety/depression on Chinese IBD patients. |
| T5 | 462-614 | Sentence | denotes | The aim of this study was to find out the prevalence of symptoms of anxiety/depression in Chinese IBD population and its impact on IBD-related features. |
| T6 | 615-692 | Sentence | denotes | This is a cross-sectional study from the southwest China IBD referral center. |
| T7 | 693-851 | Sentence | denotes | Eligible participants were divided into those with symptoms of anxiety/depression and those without based on the Hospital Anxiety and Depression Scale (HADS). |
| T8 | 852-1082 | Sentence | denotes | Demographic data and disease duration, IBD-related surgery, tobacco use, extra-intestinal manifestations, disease activity scores, endoscopic evaluation, laboratory data and current medication use were compared between two groups. |
| T9 | 1083-1184 | Sentence | denotes | A total of 341 IBD patients [221 Crohn's disease (CD) and 120 ulcerative colitis (UC)] were included. |
| T10 | 1185-1251 | Sentence | denotes | The prevalence of symptoms of anxiety/depression in IBD was 33.1%. |
| T11 | 1252-1399 | Sentence | denotes | CD patients with symptoms of anxiety/depression tended to have higher scores of simple endoscopic scores for Crohn's disease (SES-CD) (p = 0.0005). |
| T12 | 1400-1619 | Sentence | denotes | UC patients with symptoms of anxiety/depression had a significantly higher Mayo score (p = 0.0017) and ulcerative colitis endoscopic index of severity (UCEIS) (p < 0.0001) than their non-anxiety/depression counterparts. |
| T13 | 1620-1900 | Sentence | denotes | CD-related surgery (p = 0.012) and Crohn's disease activity index (CDAI) (p < 0.0001) were identified as independent risk factors for symptoms of anxiety/depression in CD, while corticosteroid use (p = 0.036) as an independent risk factor for symptoms of anxiety/depression in UC. |
| T14 | 1901-2112 | Sentence | denotes | This study helps our understanding of the prevalence of symptoms of anxiety/depression in IBD patients and its impact on IBD course and reminds us to pay more attention on IBD management with anxiety/depression. |
| T1 | 0-93 | Sentence | denotes | Symptoms of anxiety/depression is associated with more aggressive inflammatory bowel disease. |
| T2 | 94-232 | Sentence | denotes | Studies have demonstrated that inflammatory bowel disease (IBD) patients are at an increased risk of developing anxiety and/or depression. |
| T3 | 233-357 | Sentence | denotes | IBD patients with depression/anxiety have higher rates of hospitalization and increased disease severity than those without. |
| T4 | 358-461 | Sentence | denotes | So far, there is a paucity of data concerning the impact of anxiety/depression on Chinese IBD patients. |
| T5 | 462-614 | Sentence | denotes | The aim of this study was to find out the prevalence of symptoms of anxiety/depression in Chinese IBD population and its impact on IBD-related features. |
| T6 | 615-692 | Sentence | denotes | This is a cross-sectional study from the southwest China IBD referral center. |
| T7 | 693-851 | Sentence | denotes | Eligible participants were divided into those with symptoms of anxiety/depression and those without based on the Hospital Anxiety and Depression Scale (HADS). |
| T8 | 852-1082 | Sentence | denotes | Demographic data and disease duration, IBD-related surgery, tobacco use, extra-intestinal manifestations, disease activity scores, endoscopic evaluation, laboratory data and current medication use were compared between two groups. |
| T9 | 1083-1184 | Sentence | denotes | A total of 341 IBD patients [221 Crohn's disease (CD) and 120 ulcerative colitis (UC)] were included. |
| T10 | 1185-1251 | Sentence | denotes | The prevalence of symptoms of anxiety/depression in IBD was 33.1%. |
| T11 | 1252-1399 | Sentence | denotes | CD patients with symptoms of anxiety/depression tended to have higher scores of simple endoscopic scores for Crohn's disease (SES-CD) (p = 0.0005). |
| T12 | 1400-1619 | Sentence | denotes | UC patients with symptoms of anxiety/depression had a significantly higher Mayo score (p = 0.0017) and ulcerative colitis endoscopic index of severity (UCEIS) (p < 0.0001) than their non-anxiety/depression counterparts. |
| T13 | 1620-1900 | Sentence | denotes | CD-related surgery (p = 0.012) and Crohn's disease activity index (CDAI) (p < 0.0001) were identified as independent risk factors for symptoms of anxiety/depression in CD, while corticosteroid use (p = 0.036) as an independent risk factor for symptoms of anxiety/depression in UC. |
| T14 | 1901-2112 | Sentence | denotes | This study helps our understanding of the prevalence of symptoms of anxiety/depression in IBD patients and its impact on IBD course and reminds us to pay more attention on IBD management with anxiety/depression. |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 931-941 | Body_part | denotes | intestinal | http://purl.obolibrary.org/obo/MAT_0000043 |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 12-30 | Disease | denotes | anxiety/depression | http://purl.obolibrary.org/obo/MONDO_0041086 |
| T2 | 66-92 | Disease | denotes | inflammatory bowel disease | http://purl.obolibrary.org/obo/MONDO_0005265 |
| T3 | 125-151 | Disease | denotes | inflammatory bowel disease | http://purl.obolibrary.org/obo/MONDO_0005265 |
| T4 | 153-156 | Disease | denotes | IBD | http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265 |
| T6 | 206-231 | Disease | denotes | anxiety and/or depression | http://purl.obolibrary.org/obo/MONDO_0041086 |
| T7 | 233-236 | Disease | denotes | IBD | http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265 |
| T9 | 251-261 | Disease | denotes | depression | http://purl.obolibrary.org/obo/MONDO_0002050 |
| T10 | 262-269 | Disease | denotes | anxiety | http://purl.obolibrary.org/obo/MONDO_0005618|http://purl.obolibrary.org/obo/MONDO_0011918 |
| T12 | 418-436 | Disease | denotes | anxiety/depression | http://purl.obolibrary.org/obo/MONDO_0041086 |
| T13 | 448-451 | Disease | denotes | IBD | http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265 |
| T15 | 530-548 | Disease | denotes | anxiety/depression | http://purl.obolibrary.org/obo/MONDO_0041086 |
| T16 | 560-563 | Disease | denotes | IBD | http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265 |
| T18 | 593-596 | Disease | denotes | IBD | http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265 |
| T20 | 672-675 | Disease | denotes | IBD | http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265 |
| T22 | 756-774 | Disease | denotes | anxiety/depression | http://purl.obolibrary.org/obo/MONDO_0041086 |
| T23 | 815-837 | Disease | denotes | Anxiety and Depression | http://purl.obolibrary.org/obo/MONDO_0041086 |
| T24 | 891-894 | Disease | denotes | IBD | http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265 |
| T26 | 1098-1101 | Disease | denotes | IBD | http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265 |
| T28 | 1116-1131 | Disease | denotes | Crohn's disease | http://purl.obolibrary.org/obo/MONDO_0005011 |
| T29 | 1133-1135 | Disease | denotes | CD | http://purl.obolibrary.org/obo/MONDO_0005011 |
| T30 | 1145-1163 | Disease | denotes | ulcerative colitis | http://purl.obolibrary.org/obo/MONDO_0005101|http://purl.obolibrary.org/obo/MONDO_0009960 |
| T32 | 1165-1167 | Disease | denotes | UC | http://purl.obolibrary.org/obo/MONDO_0005101 |
| T33 | 1215-1233 | Disease | denotes | anxiety/depression | http://purl.obolibrary.org/obo/MONDO_0041086 |
| T34 | 1237-1240 | Disease | denotes | IBD | http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265 |
| T36 | 1252-1254 | Disease | denotes | CD | http://purl.obolibrary.org/obo/MONDO_0005011 |
| T37 | 1281-1299 | Disease | denotes | anxiety/depression | http://purl.obolibrary.org/obo/MONDO_0041086 |
| T38 | 1361-1376 | Disease | denotes | Crohn's disease | http://purl.obolibrary.org/obo/MONDO_0005011 |
| T39 | 1382-1384 | Disease | denotes | CD | http://purl.obolibrary.org/obo/MONDO_0005011 |
| T40 | 1400-1402 | Disease | denotes | UC | http://purl.obolibrary.org/obo/MONDO_0005101 |
| T41 | 1429-1447 | Disease | denotes | anxiety/depression | http://purl.obolibrary.org/obo/MONDO_0041086 |
| T42 | 1503-1521 | Disease | denotes | ulcerative colitis | http://purl.obolibrary.org/obo/MONDO_0005101|http://purl.obolibrary.org/obo/MONDO_0009960 |
| T44 | 1587-1605 | Disease | denotes | anxiety/depression | http://purl.obolibrary.org/obo/MONDO_0041086 |
| T45 | 1620-1622 | Disease | denotes | CD | http://purl.obolibrary.org/obo/MONDO_0005011 |
| T46 | 1655-1670 | Disease | denotes | Crohn's disease | http://purl.obolibrary.org/obo/MONDO_0005011 |
| T47 | 1687-1691 | Disease | denotes | CDAI | http://purl.obolibrary.org/obo/MONDO_0020337 |
| T48 | 1766-1784 | Disease | denotes | anxiety/depression | http://purl.obolibrary.org/obo/MONDO_0041086 |
| T49 | 1788-1790 | Disease | denotes | CD | http://purl.obolibrary.org/obo/MONDO_0005011 |
| T50 | 1875-1893 | Disease | denotes | anxiety/depression | http://purl.obolibrary.org/obo/MONDO_0041086 |
| T51 | 1897-1899 | Disease | denotes | UC | http://purl.obolibrary.org/obo/MONDO_0005101 |
| T52 | 1969-1987 | Disease | denotes | anxiety/depression | http://purl.obolibrary.org/obo/MONDO_0041086 |
| T53 | 1991-1994 | Disease | denotes | IBD | http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265 |
| T55 | 2022-2025 | Disease | denotes | IBD | http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265 |
| T57 | 2073-2076 | Disease | denotes | IBD | http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265 |
| T59 | 2093-2111 | Disease | denotes | anxiety/depression | http://purl.obolibrary.org/obo/MONDO_0041086 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 666-671 | OrganismTaxon | denotes | China | 3034371 |
| T2 | 912-919 | OrganismTaxon | denotes | tobacco | 4097 |
| T3 | 1475-1479 | OrganismTaxon | denotes | Mayo | 162683 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 79-84 | Body_part | denotes | bowel | http://purl.obolibrary.org/obo/UBERON_0000160 |
| T2 | 138-143 | Body_part | denotes | bowel | http://purl.obolibrary.org/obo/UBERON_0000160 |
| T3 | 838-843 | Body_part | denotes | Scale | http://purl.obolibrary.org/obo/UBERON_0002542 |
HP-phenotype
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 12-19 | Phenotype | denotes | anxiety | HP:0000739 |
| T2 | 20-30 | Phenotype | denotes | depression | HP:0000716 |
| T3 | 66-92 | Phenotype | denotes | inflammatory bowel disease | HP:0002037 |
| T4 | 125-151 | Phenotype | denotes | inflammatory bowel disease | HP:0002037 |
| T5 | 153-156 | Phenotype | denotes | IBD | HP:0002037 |
| T6 | 206-213 | Phenotype | denotes | anxiety | HP:0000739 |
| T7 | 221-231 | Phenotype | denotes | depression | HP:0000716 |
| T8 | 233-236 | Phenotype | denotes | IBD | HP:0002037 |
| T9 | 251-261 | Phenotype | denotes | depression | HP:0000716 |
| T10 | 262-269 | Phenotype | denotes | anxiety | HP:0000739 |
| T11 | 418-425 | Phenotype | denotes | anxiety | HP:0000739 |
| T12 | 426-436 | Phenotype | denotes | depression | HP:0000716 |
| T13 | 448-451 | Phenotype | denotes | IBD | HP:0002037 |
| T14 | 530-537 | Phenotype | denotes | anxiety | HP:0000739 |
| T15 | 538-548 | Phenotype | denotes | depression | HP:0000716 |
| T16 | 560-563 | Phenotype | denotes | IBD | HP:0002037 |
| T17 | 593-596 | Phenotype | denotes | IBD | HP:0002037 |
| T18 | 672-675 | Phenotype | denotes | IBD | HP:0002037 |
| T19 | 756-763 | Phenotype | denotes | anxiety | HP:0000739 |
| T20 | 764-774 | Phenotype | denotes | depression | HP:0000716 |
| T21 | 815-822 | Phenotype | denotes | Anxiety | HP:0000739 |
| T22 | 827-837 | Phenotype | denotes | Depression | HP:0000716 |
| T23 | 891-894 | Phenotype | denotes | IBD | HP:0002037 |
| T24 | 1098-1101 | Phenotype | denotes | IBD | HP:0002037 |
| T25 | 1116-1131 | Phenotype | denotes | Crohn's disease | HP:0100280 |
| T26 | 1133-1135 | Phenotype | denotes | CD | HP:0100280 |
| T27 | 1145-1163 | Phenotype | denotes | ulcerative colitis | HP:0100279 |
| T28 | 1165-1167 | Phenotype | denotes | UC | HP:0100279 |
| T29 | 1215-1222 | Phenotype | denotes | anxiety | HP:0000739 |
| T30 | 1223-1233 | Phenotype | denotes | depression | HP:0000716 |
| T31 | 1237-1240 | Phenotype | denotes | IBD | HP:0002037 |
| T32 | 1252-1254 | Phenotype | denotes | CD | HP:0100280 |
| T33 | 1281-1288 | Phenotype | denotes | anxiety | HP:0000739 |
| T34 | 1289-1299 | Phenotype | denotes | depression | HP:0000716 |
| T35 | 1361-1376 | Phenotype | denotes | Crohn's disease | HP:0100280 |
| T36 | 1382-1384 | Phenotype | denotes | CD | HP:0100280 |
| T37 | 1400-1402 | Phenotype | denotes | UC | HP:0100279 |
| T38 | 1429-1436 | Phenotype | denotes | anxiety | HP:0000739 |
| T39 | 1437-1447 | Phenotype | denotes | depression | HP:0000716 |
| T40 | 1503-1521 | Phenotype | denotes | ulcerative colitis | HP:0100279 |
| T41 | 1587-1594 | Phenotype | denotes | anxiety | HP:0000739 |
| T42 | 1595-1605 | Phenotype | denotes | depression | HP:0000716 |
| T43 | 1620-1622 | Phenotype | denotes | CD | HP:0100280 |
| T44 | 1655-1670 | Phenotype | denotes | Crohn's disease | HP:0100280 |
| T45 | 1766-1773 | Phenotype | denotes | anxiety | HP:0000739 |
| T46 | 1774-1784 | Phenotype | denotes | depression | HP:0000716 |
| T47 | 1788-1790 | Phenotype | denotes | CD | HP:0100280 |
| T48 | 1875-1882 | Phenotype | denotes | anxiety | HP:0000739 |
| T49 | 1883-1893 | Phenotype | denotes | depression | HP:0000716 |
| T50 | 1897-1899 | Phenotype | denotes | UC | HP:0100279 |
| T51 | 1969-1976 | Phenotype | denotes | anxiety | HP:0000739 |
| T52 | 1977-1987 | Phenotype | denotes | depression | HP:0000716 |
| T53 | 1991-1994 | Phenotype | denotes | IBD | HP:0002037 |
| T54 | 2022-2025 | Phenotype | denotes | IBD | HP:0002037 |
| T55 | 2073-2076 | Phenotype | denotes | IBD | HP:0002037 |
| T56 | 2093-2100 | Phenotype | denotes | anxiety | HP:0000739 |
| T57 | 2101-2111 | Phenotype | denotes | depression | HP:0000716 |