PubMed:33376581 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/33376581","sourcedb":"PubMed","sourceid":"33376581","source_url":"https://www.ncbi.nlm.nih.gov/pubmed/33376581","text":"Effects of Fasting-Mimicking Diet and Specific Meal Replacement Foods on Blood Glucose Control in Patients with Type 2 Diabetes: A Randomized Controlled Trial.\nType 2 diabetes represents a serious societal health problem due to the vulnerability to cardiovascular events. Diet therapy is the most basic treatment for type 2 diabetes. The present study was conducted to study the effect of a fasting-mimicking diet and specific meal replacement foods on blood glucose control in patients with type 2 diabetes. Our study included 100 patients with type 2 diabetes who underwent a physical examination which were enrolled and randomly assigned as 50 patients each to the test group (with low energy-specific meal replacement meals during a fasting-mimicking diet) and the control group (with specific meal replacement foods given normal adult doses). After 4 months, efficacy indicators which were fasting blood glucose, 2-hour postprandial venous blood glucose, and glycosylated haemoglobin of the experimental group were all lower than those of the control group (P \u003c 0.05); observation indicators that include body mass index, waist circumference, blood lipids (triglyceride, cholesterol, and low-density lipoprotein), and blood pressure levels were all lower than the control group, and high-density lipoprotein levels were all higher than the control group (all P \u003c 0.05). Both groups of fasting blood glucose, 2-hour postprandial venous blood glucose, and blood pressure had a relatively stable downward trend, but the experimental group had a more significant decline. In conclusion, the study revealed that a fasting-mimicking diet and specific meal replacement foods can safely and effectively reduce weight and improve metabolic syndrome in patients with type 2 diabetes.","tracks":[{"project":"wangzhuo19_800_2","denotations":[{"id":"T1","span":{"begin":112,"end":127},"obj":"DP"},{"id":"T2","span":{"begin":317,"end":332},"obj":"DP"},{"id":"T3","span":{"begin":492,"end":507},"obj":"DP"},{"id":"T4","span":{"begin":160,"end":175},"obj":"DP"},{"id":"T5","span":{"begin":1762,"end":1777},"obj":"DP"},{"id":"T6","span":{"begin":546,"end":561},"obj":"DP"}],"attributes":[{"subj":"T1","pred":"source","obj":"wangzhuo19_800_2"},{"subj":"T2","pred":"source","obj":"wangzhuo19_800_2"},{"subj":"T3","pred":"source","obj":"wangzhuo19_800_2"},{"subj":"T4","pred":"source","obj":"wangzhuo19_800_2"},{"subj":"T5","pred":"source","obj":"wangzhuo19_800_2"},{"subj":"T6","pred":"source","obj":"wangzhuo19_800_2"}]},{"project":"Zierdiyeerkenaili_800_2","denotations":[{"id":"T1","span":{"begin":112,"end":127},"obj":"DP"},{"id":"T2","span":{"begin":317,"end":332},"obj":"DP"},{"id":"T3","span":{"begin":492,"end":507},"obj":"DP"},{"id":"T4","span":{"begin":546,"end":561},"obj":"DP"},{"id":"T5","span":{"begin":1762,"end":1777},"obj":"DP"}],"attributes":[{"subj":"T1","pred":"source","obj":"Zierdiyeerkenaili_800_2"},{"subj":"T2","pred":"source","obj":"Zierdiyeerkenaili_800_2"},{"subj":"T3","pred":"source","obj":"Zierdiyeerkenaili_800_2"},{"subj":"T4","pred":"source","obj":"Zierdiyeerkenaili_800_2"},{"subj":"T5","pred":"source","obj":"Zierdiyeerkenaili_800_2"}]},{"project":"yaoziqian_800_2","denotations":[{"id":"T1","span":{"begin":112,"end":127},"obj":"DP"},{"id":"T2","span":{"begin":160,"end":175},"obj":"DP"},{"id":"T3","span":{"begin":317,"end":332},"obj":"DP"},{"id":"T4","span":{"begin":492,"end":507},"obj":"DP"},{"id":"T5","span":{"begin":546,"end":561},"obj":"DP"},{"id":"T6","span":{"begin":1762,"end":1777},"obj":"DP"}],"attributes":[{"subj":"T1","pred":"source","obj":"yaoziqian_800_2"},{"subj":"T2","pred":"source","obj":"yaoziqian_800_2"},{"subj":"T3","pred":"source","obj":"yaoziqian_800_2"},{"subj":"T4","pred":"source","obj":"yaoziqian_800_2"},{"subj":"T5","pred":"source","obj":"yaoziqian_800_2"},{"subj":"T6","pred":"source","obj":"yaoziqian_800_2"}]},{"project":"chenxin_473849_800_3","denotations":[{"id":"T1","span":{"begin":112,"end":127},"obj":"DP"},{"id":"T2","span":{"begin":160,"end":175},"obj":"DP"},{"id":"T3","span":{"begin":317,"end":332},"obj":"DP"},{"id":"T4","span":{"begin":492,"end":507},"obj":"DP"},{"id":"T5","span":{"begin":546,"end":561},"obj":"DP"},{"id":"T6","span":{"begin":1762,"end":1777},"obj":"DP"}],"attributes":[{"subj":"T1","pred":"source","obj":"chenxin_473849_800_3"},{"subj":"T2","pred":"source","obj":"chenxin_473849_800_3"},{"subj":"T3","pred":"source","obj":"chenxin_473849_800_3"},{"subj":"T4","pred":"source","obj":"chenxin_473849_800_3"},{"subj":"T5","pred":"source","obj":"chenxin_473849_800_3"},{"subj":"T6","pred":"source","obj":"chenxin_473849_800_3"}]},{"project":"yangbin123xm_800_3","denotations":[{"id":"T1","span":{"begin":112,"end":127},"obj":"DP"},{"id":"T2","span":{"begin":317,"end":332},"obj":"DP"},{"id":"T3","span":{"begin":492,"end":507},"obj":"DP"},{"id":"T4","span":{"begin":546,"end":561},"obj":"DP"},{"id":"T5","span":{"begin":1762,"end":1777},"obj":"DP"},{"id":"T6","span":{"begin":160,"end":175},"obj":"DP"}],"attributes":[{"subj":"T1","pred":"source","obj":"yangbin123xm_800_3"},{"subj":"T2","pred":"source","obj":"yangbin123xm_800_3"},{"subj":"T3","pred":"source","obj":"yangbin123xm_800_3"},{"subj":"T4","pred":"source","obj":"yangbin123xm_800_3"},{"subj":"T5","pred":"source","obj":"yangbin123xm_800_3"},{"subj":"T6","pred":"source","obj":"yangbin123xm_800_3"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"wangzhuo19_800_2","color":"#ec93da","default":true},{"id":"Zierdiyeerkenaili_800_2","color":"#93ece3"},{"id":"yaoziqian_800_2","color":"#ecc993"},{"id":"chenxin_473849_800_3","color":"#af93ec"},{"id":"yangbin123xm_800_3","color":"#93ec95"}]}]}}