PubMed:33162738
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T1 | 826-831 | Body_part | denotes | serum | http://purl.org/sig/ont/fma/fma63083 |
| T2 | 915-920 | Body_part | denotes | serum | http://purl.org/sig/ont/fma/fma63083 |
| T3 | 921-928 | Body_part | denotes | alanine | http://purl.org/sig/ont/fma/fma82749 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 826-831 | Body_part | denotes | serum | http://purl.obolibrary.org/obo/UBERON_0001977 |
| T2 | 915-920 | Body_part | denotes | serum | http://purl.obolibrary.org/obo/UBERON_0001977 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 38-46 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T2 | 97-105 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T3 | 278-286 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T4 | 738-746 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T5 | 772-780 | Disease | denotes | diarrhea | http://purl.obolibrary.org/obo/MONDO_0001673 |
| T6 | 1226-1234 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T7 | 1264-1272 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T8 | 1378-1386 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 115-118 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T2 | 127-128 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T3 | 199-200 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T4 | 430-432 | http://purl.obolibrary.org/obo/CLO_0007622 | denotes | MD |
| T5 | 497-498 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T6 | 538-542 | http://purl.obolibrary.org/obo/CLO_0001625 | denotes | a 95 |
| T7 | 606-607 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T8 | 677-683 | http://purl.obolibrary.org/obo/UBERON_0003100 | denotes | female |
| T9 | 1030-1032 | http://purl.obolibrary.org/obo/CLO_0007622 | denotes | MD |
| T10 | 1082-1084 | http://purl.obolibrary.org/obo/CLO_0007622 | denotes | MD |
| T11 | 1149-1151 | http://purl.obolibrary.org/obo/CLO_0007622 | denotes | MD |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T2 | 832-841 | Chemical | denotes | aspartate | http://purl.obolibrary.org/obo/CHEBI_132943|http://purl.obolibrary.org/obo/CHEBI_29995|http://purl.obolibrary.org/obo/CHEBI_72314 |
| T5 | 860-863 | Chemical | denotes | AST | http://purl.obolibrary.org/obo/CHEBI_76649 |
| T6 | 921-928 | Chemical | denotes | alanine | http://purl.obolibrary.org/obo/CHEBI_16449 |
| T7 | 1025-1028 | Chemical | denotes | AST | http://purl.obolibrary.org/obo/CHEBI_76649 |
| T8 | 1030-1032 | Chemical | denotes | MD | http://purl.obolibrary.org/obo/CHEBI_74699 |
| T9 | 1082-1084 | Chemical | denotes | MD | http://purl.obolibrary.org/obo/CHEBI_74699 |
| T10 | 1138-1147 | Chemical | denotes | bilirubin | http://purl.obolibrary.org/obo/CHEBI_16990 |
| T11 | 1149-1151 | Chemical | denotes | MD | http://purl.obolibrary.org/obo/CHEBI_74699 |
| T12 | 1235-1240 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T13 | 1273-1278 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T1 | 430-432 | Chemical | denotes | MD | http://purl.obolibrary.org/obo/CHEBI_74699 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 1 | 38-46 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 16 | 97-105 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 17 | 278-286 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 18 | 635-643 | Species | denotes | patients | Tax:9606 |
| 19 | 738-746 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 20 | 772-780 | Disease | denotes | diarrhea | MESH:D003967 |
| 21 | 832-858 | Gene | denotes | aspartate aminotransferase | Gene:26503 |
| 22 | 860-863 | Gene | denotes | AST | Gene:26503 |
| 23 | 921-945 | Gene | denotes | alanine aminotransferase | Gene:2875 |
| 24 | 1025-1028 | Gene | denotes | AST | Gene:26503 |
| 25 | 1138-1147 | Chemical | denotes | bilirubin | MESH:D001663 |
| 26 | 1226-1234 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 27 | 1264-1272 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 28 | 1292-1317 | Disease | denotes | Gastrointestinal symptoms | MESH:D012817 |
| 29 | 1378-1386 | Disease | denotes | COVID-19 | MESH:C000657245 |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 772-780 | Phenotype | denotes | diarrhea | http://purl.obolibrary.org/obo/HP_0002014 |
| T2 | 817-858 | Phenotype | denotes | elevated serum aspartate aminotransferase | http://purl.obolibrary.org/obo/HP_0031956 |
| T3 | 906-945 | Phenotype | denotes | elevated serum alanine aminotransferase | http://purl.obolibrary.org/obo/HP_0031964 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-84 | Sentence | denotes | Gastrointestinal predictors of severe COVID-19: systematic review and meta-analysis. |
| T2 | 85-185 | Sentence | denotes | Background: COVID-19 pandemic has created a need to identify potential predictors of severe disease. |
| T3 | 186-287 | Sentence | denotes | We performed a systematic review and meta-analysis of gastrointestinal predictors of severe COVID-19. |
| T4 | 288-296 | Sentence | denotes | Methods: |
| T5 | 297-392 | Sentence | denotes | An extensive literature search was performed using PubMed, Embase, Web of Science and Cochrane. |
| T6 | 393-519 | Sentence | denotes | Odds ratio (OR) and mean difference (MD) were calculated for proportional and continuous outcomes using a random-effect model. |
| T7 | 520-596 | Sentence | denotes | For each outcome, a 95% confidence interval (CI) and P-value were generated. |
| T8 | 597-605 | Sentence | denotes | Results: |
| T9 | 606-699 | Sentence | denotes | A total of 83 studies (26912 patients, mean age 43.5±16.4 years, 48.2% female) were included. |
| T10 | 700-988 | Sentence | denotes | Gastrointestinal predictors of severe COVID-19 included the presence of diarrhea (OR 1.50, 95%CI 1.10-2.03; P=0.01), elevated serum aspartate aminotransferase (AST) (OR 4.00, 95%CI 3.02-5.28; P<0.001), and elevated serum alanine aminotransferase (ALT) (OR 2.54, 95%CI 1.91-3.37; P<0.001). |
| T11 | 989-1279 | Sentence | denotes | Significantly higher levels of mean AST (MD 14.78 U/L, 95%CI 11.70-17.86 U/L; P<0.001), ALT (MD 11.87 U/L, 95%CI 9.23-14.52 U/L; P<0.001), and total bilirubin (MD 2.08 mmol/L, 95%CI 1.36-2.80 mmol/L; P<0.001) were observed in the severe COVID-19 group compared to non-severe COVID-19 group. |
| T12 | 1280-1291 | Sentence | denotes | Conclusion: |
| T13 | 1292-1387 | Sentence | denotes | Gastrointestinal symptoms and biomarkers should be assessed early to recognize severe COVID-19. |