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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 437-447 Body_part denotes epithelium http://purl.org/sig/ont/fma/fma9639
T2 854-859 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T3 888-892 Body_part denotes skin http://purl.org/sig/ont/fma/fma7163

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 437-447 Body_part denotes epithelium http://purl.obolibrary.org/obo/UBERON_0000483
T2 888-892 Body_part denotes skin http://purl.obolibrary.org/obo/UBERON_0000014

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 126-134 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T2 139-155 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T3 353-361 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T4 705-727 Disease denotes respiratory infections http://purl.obolibrary.org/obo/MONDO_0024355
T5 1046-1054 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T6 1171-1193 Disease denotes respiratory infections http://purl.obolibrary.org/obo/MONDO_0024355
T7 1202-1211 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T8 1246-1258 Disease denotes dengue fever http://purl.obolibrary.org/obo/MONDO_0005502
T9 1380-1396 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T10 1482-1490 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T11 1664-1672 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T12 1683-1699 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 0-1 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T2 40-41 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T3 278-279 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T4 381-382 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T5 407-415 http://purl.obolibrary.org/obo/CLO_0001658 denotes actively
T6 425-447 http://purl.obolibrary.org/obo/UBERON_0004802 denotes respiratory epithelium
T7 759-760 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T8 804-805 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T9 854-859 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T10 864-867 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T11 888-892 http://purl.obolibrary.org/obo/UBERON_0000014 denotes skin
T12 888-892 http://purl.obolibrary.org/obo/UBERON_0001003 denotes skin
T13 888-892 http://purl.obolibrary.org/obo/UBERON_0002097 denotes skin
T14 888-892 http://purl.obolibrary.org/obo/UBERON_0002199 denotes skin
T15 888-892 http://www.ebi.ac.uk/efo/EFO_0000962 denotes skin
T16 1235-1240 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T17 1586-1587 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1 11-22 Chemical denotes application http://purl.obolibrary.org/obo/CHEBI_33232
T2 50-54 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T4 55-64 Chemical denotes ionophore http://purl.obolibrary.org/obo/CHEBI_24869
T5 69-89 Chemical denotes anti-infective agent http://purl.obolibrary.org/obo/CHEBI_35441
T6 187-191 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T8 192-201 Chemical denotes ionophore http://purl.obolibrary.org/obo/CHEBI_24869
T9 545-549 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T11 729-739 Chemical denotes Hinokitiol http://purl.obolibrary.org/obo/CHEBI_10447
T12 769-782 Chemical denotes monoterpenoid http://purl.obolibrary.org/obo/CHEBI_25409
T13 811-815 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T15 816-825 Chemical denotes ionophore http://purl.obolibrary.org/obo/CHEBI_24869
T16 834-838 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T18 948-957 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T19 959-972 Chemical denotes antimicrobial http://purl.obolibrary.org/obo/CHEBI_33281
T20 974-984 Chemical denotes antifungal http://purl.obolibrary.org/obo/CHEBI_35718
T21 1131-1136 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T22 1415-1433 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T23 1458-1462 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T25 1463-1472 Chemical denotes ionophore http://purl.obolibrary.org/obo/CHEBI_24869
T26 1473-1477 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T27 1588-1592 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T29 1593-1602 Chemical denotes ionophore http://purl.obolibrary.org/obo/CHEBI_24869
T30 1607-1627 Chemical denotes anti-infective agent http://purl.obolibrary.org/obo/CHEBI_35441

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 55-64 http://purl.obolibrary.org/obo/GO_0022809 denotes ionophore
T2 139-155 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T3 192-201 http://purl.obolibrary.org/obo/GO_0022809 denotes ionophore
T4 522-533 http://purl.obolibrary.org/obo/GO_0065007 denotes regulations
T5 589-606 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T6 589-606 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T7 816-825 http://purl.obolibrary.org/obo/GO_0022809 denotes ionophore
T8 834-848 http://purl.obolibrary.org/obo/GO_0006829 denotes zinc transport
T9 839-848 http://purl.obolibrary.org/obo/GO_0006810 denotes transport
T10 1380-1396 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T11 1463-1472 http://purl.obolibrary.org/obo/GO_0022809 denotes ionophore
T12 1593-1602 http://purl.obolibrary.org/obo/GO_0022809 denotes ionophore
T13 1683-1699 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
3 26-36 Chemical denotes hinokitiol MESH:C009479
4 126-134 Disease denotes COVID-19 MESH:C000657245
5 139-155 Disease denotes viral infections MESH:D001102
27 353-361 Disease denotes COVID-19 MESH:C000657245
28 425-436 Species denotes respiratory Tax:12814
29 650-656 Disease denotes stress MESH:D000079225
30 691-699 Species denotes patients Tax:9606
31 705-727 Disease denotes respiratory infections MESH:D012141
32 729-739 Chemical denotes Hinokitiol MESH:C009479
33 741-754 Chemical denotes β-thujaplicin MESH:C009479
34 769-782 Chemical denotes monoterpenoid MESH:D039821
35 1046-1054 Disease denotes COVID-19 MESH:C000657245
36 1098-1107 Disease denotes mortality MESH:D003643
37 1140-1148 Species denotes patients Tax:9606
38 1171-1193 Disease denotes respiratory infections MESH:D012141
39 1213-1240 Species denotes respiratory syncytial virus Tax:12814
40 1253-1258 Disease denotes fever MESH:D005334
41 1380-1396 Disease denotes viral infections MESH:D001102
42 1415-1433 Chemical denotes hydroxychloroquine MESH:D006886
43 1435-1438 Chemical denotes HCQ MESH:D006886
44 1482-1490 Disease denotes COVID-19 MESH:C000657245
45 1572-1582 Chemical denotes hinokitiol MESH:C009479
46 1664-1672 Disease denotes COVID-19 MESH:C000657245
47 1683-1699 Disease denotes viral infections MESH:D001102

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T1 0-156 Sentence denotes A possible application of hinokitiol as a natural zinc ionophore and anti-infective agent for the prevention and treatment of COVID-19 and viral infections.
T2 157-372 Sentence denotes Zinc and the combination with zinc ionophore have been reported in basic research and several clinical investigations as a potentially viable and economical preventive and therapeutic options for COVID-19 treatment.
T3 373-534 Sentence denotes Zinc is a vital microelement that actively supports respiratory epithelium barrier integrity, innate and adaptive immune functions, and inflammatory regulations.
T4 535-728 Sentence denotes Moreover, zinc may also prevent viral entry, suppress viral replication, and mitigate the damages due to oxidative stress and hyperinflammatory reaction in patients with respiratory infections.
T5 729-860 Sentence denotes Hinokitiol (β-thujaplicin) is a natural monoterpenoid and is considered as a safe zinc ionophore to help zinc transport into cells.
T6 861-1033 Sentence denotes It has been widely used in skin and oral care, and therapeutic products for its potent antiviral, antimicrobial, antifungal, anti-inflammatory, and anticancer applications.
T7 1034-1259 Sentence denotes The ongoing COVID-19 pandemic and the significant morbidity and mortality exist in the high-risk group of patients associated with other respiratory infections such as influenza, respiratory syncytial virus, and dengue fever.
T8 1260-1397 Sentence denotes There is an urgent need for the development of inexpensive, safe, and effective therapeutics to prevent and treat these viral infections.
T9 1398-1700 Sentence denotes Considering that hydroxychloroquine (HCQ), the most studied zinc ionophore drug for COVID-19, is linked to potentially serious side effects, we propose the implementation of hinokitiol as a zinc ionophore and anti-infective agent for the prevention and treatment of COVID-19 and other viral infections.

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 640-656 Phenotype denotes oxidative stress http://purl.obolibrary.org/obo/HP_0025464
T2 705-727 Phenotype denotes respiratory infections http://purl.obolibrary.org/obo/HP_0011947
T3 1171-1193 Phenotype denotes respiratory infections http://purl.obolibrary.org/obo/HP_0011947
T4 1253-1258 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945

hydroxychloroquine

Id Subject Object Predicate Lexical cue hp_id
T1 640-656 Phenotype denotes oxidative stress http://purl.obolibrary.org/obo/HP_0025464
T2 705-727 Phenotype denotes respiratory infections http://purl.obolibrary.org/obo/HP_0011947
T3 1171-1193 Phenotype denotes respiratory infections http://purl.obolibrary.org/obo/HP_0011947
T4 1253-1258 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945