PubMed:33044019
Annnotations
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 35-43 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T2 | 140-148 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T3 | 255-263 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T4 | 667-675 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T5 | 1485-1493 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T6 | 1635-1645 | Disease | denotes | arrhythmia | http://purl.obolibrary.org/obo/MONDO_0007263 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 177-182 | http://purl.obolibrary.org/obo/CLO_0007225 | denotes | label |
| T2 | 193-194 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T3 | 211-221 | http://purl.obolibrary.org/obo/BFO_0000030 | denotes | OBJECTIVES |
| T4 | 239-240 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T5 | 494-496 | http://purl.obolibrary.org/obo/CLO_0001382 | denotes | 48 |
| T6 | 652-653 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T7 | 755-759 | http://purl.obolibrary.org/obo/UBERON_0003101 | denotes | male |
| T8 | 755-759 | http://www.ebi.ac.uk/efo/EFO_0000970 | denotes | male |
| T9 | 788-792 | http://purl.obolibrary.org/obo/UBERON_0003101 | denotes | male |
| T10 | 788-792 | http://www.ebi.ac.uk/efo/EFO_0000970 | denotes | male |
| T11 | 1428-1429 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T1 | 177-182 | Chemical | denotes | label | http://purl.obolibrary.org/obo/CHEBI_35209 |
| T2 | 724-726 | Chemical | denotes | SD | http://purl.obolibrary.org/obo/CHEBI_74807 |
| T3 | 755-759 | Chemical | denotes | male | http://purl.obolibrary.org/obo/CHEBI_30780 |
| T4 | 788-792 | Chemical | denotes | male | http://purl.obolibrary.org/obo/CHEBI_30780 |
| T5 | 1064-1076 | Chemical | denotes | azithromycin | http://purl.obolibrary.org/obo/CHEBI_2955 |
| T6 | 1078-1080 | Chemical | denotes | AZ | http://purl.obolibrary.org/obo/CHEBI_2955 |
| T7 | 1082-1087 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T8 | 1176-1178 | Chemical | denotes | AZ | http://purl.obolibrary.org/obo/CHEBI_2955 |
| T9 | 1345-1347 | Chemical | denotes | AZ | http://purl.obolibrary.org/obo/CHEBI_2955 |
| T10 | 1365-1367 | Chemical | denotes | AZ | http://purl.obolibrary.org/obo/CHEBI_2955 |
| T11 | 1662-1664 | Chemical | denotes | AZ | http://purl.obolibrary.org/obo/CHEBI_2955 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 4 | 0-18 | Chemical | denotes | Hydroxychloroquine | MESH:D006886 |
| 5 | 35-43 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 6 | 44-52 | Species | denotes | patients | Tax:9606 |
| 7 | 86-95 | Disease | denotes | mortality | MESH:D003643 |
| 45 | 111-129 | Chemical | denotes | Hydroxychloroquine | MESH:D006886 |
| 46 | 131-134 | Chemical | denotes | HCQ | MESH:D006886 |
| 47 | 140-148 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 48 | 255-263 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 49 | 264-271 | Species | denotes | patient | Tax:9606 |
| 50 | 346-349 | Chemical | denotes | HCQ | MESH:D006886 |
| 51 | 389-398 | Disease | denotes | mortality | MESH:D003643 |
| 52 | 464-472 | Species | denotes | patients | Tax:9606 |
| 53 | 483-486 | Chemical | denotes | HCQ | MESH:D006886 |
| 54 | 638-646 | Species | denotes | patients | Tax:9606 |
| 55 | 667-675 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 56 | 801-804 | Chemical | denotes | HCQ | MESH:D006886 |
| 57 | 812-815 | Chemical | denotes | HCQ | MESH:D006886 |
| 58 | 880-889 | Disease | denotes | mortality | MESH:D003643 |
| 59 | 902-905 | Chemical | denotes | HCQ | MESH:D006886 |
| 60 | 913-916 | Chemical | denotes | HCQ | MESH:D006886 |
| 61 | 925-928 | Chemical | denotes | HCQ | MESH:D006886 |
| 62 | 946-949 | Chemical | denotes | HCQ | MESH:D006886 |
| 63 | 1060-1063 | Chemical | denotes | HCQ | MESH:D006886 |
| 64 | 1064-1076 | Chemical | denotes | azithromycin | MESH:D017963 |
| 65 | 1078-1080 | Chemical | denotes | AZ | |
| 66 | 1103-1112 | Disease | denotes | mortality | MESH:D003643 |
| 67 | 1171-1174 | Chemical | denotes | HCQ | MESH:D006886 |
| 68 | 1176-1178 | Chemical | denotes | AZ | |
| 69 | 1305-1314 | Disease | denotes | mortality | MESH:D003643 |
| 70 | 1341-1344 | Chemical | denotes | HCQ | MESH:D006886 |
| 71 | 1358-1361 | Chemical | denotes | HCQ | MESH:D006886 |
| 72 | 1485-1493 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 73 | 1508-1511 | Chemical | denotes | HCQ | MESH:D006886 |
| 74 | 1524-1533 | Disease | denotes | mortality | MESH:D003643 |
| 75 | 1550-1558 | Species | denotes | patients | Tax:9606 |
| 76 | 1611-1620 | Disease | denotes | mortality | MESH:D003643 |
| 77 | 1625-1634 | Disease | denotes | mortality | MESH:D003643 |
| 78 | 1635-1645 | Disease | denotes | arrhythmia | MESH:D001145 |
| 79 | 1651-1654 | Chemical | denotes | HCQ | MESH:D006886 |
| 80 | 1658-1661 | Chemical | denotes | HCQ | MESH:D006886 |
| 81 | 1662-1664 | Chemical | denotes | AZ |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-53 | Sentence | denotes | Hydroxychloroquine in hospitalized COVID-19 patients: |
| T2 | 54-96 | Sentence | denotes | Real world experience assessing mortality. |
| T3 | 97-110 | Sentence | denotes | INTRODUCTION: |
| T4 | 111-210 | Sentence | denotes | Hydroxychloroquine (HCQ) for COVID-19 is presently being used off-label or within a clinical trial. |
| T5 | 211-222 | Sentence | denotes | OBJECTIVES: |
| T6 | 223-354 | Sentence | denotes | We investigated a multinational COVID-19 patient database of real world data containing outcomes and their relationship to HCQ use. |
| T7 | 355-424 | Sentence | denotes | The primary outcome was all-cause mortality within 30 days follow-up. |
| T8 | 425-433 | Sentence | denotes | METHODS: |
| T9 | 434-525 | Sentence | denotes | Retrospective cohort study of patients receiving HCQ within 48 hours of hospital admission. |
| T10 | 526-622 | Sentence | denotes | Medications, preexisting conditions, clinical measures on admission, and outcomes were recorded. |
| T11 | 623-631 | Sentence | denotes | RESULTS: |
| T12 | 632-837 | Sentence | denotes | Among patients with a diagnosis of COVID-19 in our propensity matched cohort, the mean ages±SD were 62.3±15.9 years (53.7% male) and 61.9±16.0 years (53.0% male) in the HCQ and no-HCQ groups, respectively. |
| T13 | 838-1017 | Sentence | denotes | There was no difference in overall 30-day mortality between the HCQ and no-HCQ groups (HCQ 13.1%, n=367; No-HCQ 13.6%, n=367; OR 0.95; 95% CI 0.62-1.46) after propensity-matching. |
| T14 | 1018-1238 | Sentence | denotes | Although statistically insignificant, the HCQ/azithromycin (AZ) group had an overall mortality rate of 14.6% (n=199) compared with propensity matched no HCQ/+AZ cohort's rate of 12.1% (n=199) (OR 1.24; 95% CI 0.70-2.22). |
| T15 | 1239-1399 | Sentence | denotes | Importantly, however, there was no trend in this cohort's overall mortality/arrhythmogenesis outcome (HCQ/AZ 17.1%, No-HCQ/No AZ 17.1%; OR 1.0; 95% CI 0.6-1.7). |
| T16 | 1400-1412 | Sentence | denotes | CONCLUSIONS: |
| T17 | 1413-1559 | Sentence | denotes | We report from a large retrospective multinational database analysis of COVID-19 outcomes with HCQ and overall mortality in hospitalized patients. |
| T18 | 1560-1665 | Sentence | denotes | There was no statistically significant increase in mortality and mortality/arrhythmia with HCQ or HCQ/AZ. |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 1635-1645 | Phenotype | denotes | arrhythmia | http://purl.obolibrary.org/obo/HP_0011675 |
hydroxychloroquine
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 1635-1645 | Phenotype | denotes | arrhythmia | http://purl.obolibrary.org/obo/HP_0011675 |