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LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 52-60 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T2 240-264 Disease denotes coronavirus disease 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T3 266-274 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T4 452-461 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T5 1277-1286 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T6 1491-1499 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 66-73 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T2 75-84 http://purl.obolibrary.org/obo/BFO_0000030 denotes Objective
T3 137-138 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T4 176-177 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T5 221-228 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T6 320-325 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T7 345-346 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T8 419-426 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T9 804-809 http://purl.obolibrary.org/obo/UBERON_0007688 denotes field
T10 870-876 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T11 1044-1051 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T12 1175-1180 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T13 1203-1204 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T14 1245-1246 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T15 1392-1397 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T16 1414-1421 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T17 1505-1512 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T18 1670-1675 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T19 1695-1696 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1 485-490 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T2 1212-1217 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
1 52-60 Disease denotes COVID-19 MESH:C000657245
8 240-264 Disease denotes coronavirus disease 2019 MESH:C000657245
9 266-274 Disease denotes COVID-19 MESH:C000657245
10 452-461 Disease denotes infection MESH:D007239
11 756-762 Species denotes people Tax:9606
12 1277-1286 Disease denotes infection MESH:D007239
13 1491-1499 Disease denotes COVID-19 MESH:C000657245

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T1 0-74 Sentence denotes Simulation of pooled-sample analysis strategies for COVID-19 mass testing.
T2 75-85 Sentence denotes Objective:
T3 86-358 Sentence denotes To evaluate two pooled-sample analysis strategies (a routine high-throughput approach and a novel context-sensitive approach) for mass testing during the coronavirus disease 2019 (COVID-19) pandemic, with an emphasis on the number of tests required to screen a population.
T4 359-367 Sentence denotes Methods:
T5 368-497 Sentence denotes We used Monte Carlo simulations to compare the two testing strategies for different infection prevalences and pooled group sizes.
T6 498-633 Sentence denotes With the routine high-throughput approach, heterogeneous sample pools are formed randomly for polymerase chain reaction (PCR) analysis.
T7 634-810 Sentence denotes With the novel context-sensitive approach, PCR analysis is performed on pooled samples from homogeneous groups of similar people that have been purposively formed in the field.
T8 811-925 Sentence denotes In both approaches, all samples contributing to pools that tested positive are subsequently analysed individually.
T9 926-935 Sentence denotes Findings:
T10 936-1087 Sentence denotes Both pooled-sample strategies would save substantial resources compared to individual analysis during surge testing and enhanced epidemic surveillance.
T11 1088-1310 Sentence denotes The context-sensitive approach offers the greatest savings: for instance, 58-89% fewer tests would be required for a pooled group size of 3 to 25 samples in a population of 150 000 with an infection prevalence of 1% or 5%.
T12 1311-1422 Sentence denotes Correspondingly, the routine high-throughput strategy would require 24-80% fewer tests than individual testing.
T13 1423-1434 Sentence denotes Conclusion:
T14 1435-1513 Sentence denotes Pooled-sample PCR screening could save resources during COVID-19 mass testing.
T15 1514-1708 Sentence denotes In particular, the novel context-sensitive approach, which uses pooled samples from homogeneous population groups, could substantially reduce the number of tests required to screen a population.
T16 1709-1873 Sentence denotes Pooled-sample approaches could help countries sustain population screening over extended periods of time and thereby help contain foreseeable second-wave outbreaks.