PubMed:32876196
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T1 | 257-260 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T2 | 1285-1295 | Body_part | denotes | troponin I | http://purl.org/sig/ont/fma/fma62340 |
| T3 | 1285-1293 | Body_part | denotes | troponin | http://purl.org/sig/ont/fma/fma62338 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 11-17 | Disease | denotes | Injury | http://purl.obolibrary.org/obo/MONDO_0021178 |
| T2 | 98-106 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T3 | 209-217 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T4 | 231-239 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T5 | 298-317 | Disease | denotes | respiratory disease | http://purl.obolibrary.org/obo/MONDO_0005087 |
| T6 | 327-335 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T7 | 346-354 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T8 | 374-391 | Disease | denotes | pulmonary disease | http://purl.obolibrary.org/obo/MONDO_0005275 |
| T9 | 518-524 | Disease | denotes | injury | http://purl.obolibrary.org/obo/MONDO_0021178 |
| T10 | 614-622 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T11 | 750-756 | Disease | denotes | injury | http://purl.obolibrary.org/obo/MONDO_0021178 |
| T12 | 834-842 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T13 | 1453-1461 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T14 | 1464-1473 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T15 | 1572-1578 | Disease | denotes | injury | http://purl.obolibrary.org/obo/MONDO_0021178 |
| T16 | 1597-1605 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T17 | 1606-1615 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T18 | 1689-1697 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T19 | 1700-1709 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 178-179 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | à |
| T2 | 261-266 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T3 | 283-284 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T4 | 372-373 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T5 | 455-456 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T6 | 1019-1020 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T7 | 1312-1313 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
| T8 | 1331-1338 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptide |
| T9 | 1360-1362 | http://purl.obolibrary.org/obo/PR_000010213 | denotes | MB |
| T10 | 1774-1778 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | test |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T1 | 1331-1338 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T2 | 1344-1352 | Chemical | denotes | creatine | http://purl.obolibrary.org/obo/CHEBI_16919|http://purl.obolibrary.org/obo/CHEBI_57947 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 479-488 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | synthesis |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 4 | 0-17 | Disease | denotes | Myocardial Injury | MESH:D009202 |
| 5 | 71-80 | Disease | denotes | Mortality | MESH:D003643 |
| 6 | 84-92 | Species | denotes | Patients | Tax:9606 |
| 7 | 98-106 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 33 | 231-241 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 34 | 292-317 | Disease | denotes | acute respiratory disease | MESH:D012120 |
| 35 | 327-335 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 36 | 346-354 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 37 | 374-391 | Disease | denotes | pulmonary disease | MESH:D008171 |
| 38 | 398-406 | Species | denotes | patients | Tax:9606 |
| 39 | 419-440 | Disease | denotes | cardiovascular damage | MESH:D002318 |
| 40 | 507-524 | Disease | denotes | myocardial injury | MESH:D009202 |
| 41 | 541-562 | Disease | denotes | cardiac complications | MESH:D005117 |
| 42 | 591-596 | Disease | denotes | death | MESH:D003643 |
| 43 | 600-608 | Species | denotes | patients | Tax:9606 |
| 44 | 614-622 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 45 | 739-756 | Disease | denotes | myocardial injury | MESH:D009202 |
| 46 | 773-794 | Disease | denotes | cardiac complications | MESH:D005117 |
| 47 | 834-842 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 48 | 1133-1141 | Species | denotes | patients | Tax:9606 |
| 49 | 1368-1389 | Disease | denotes | cardiac complications | MESH:D005117 |
| 50 | 1429-1434 | Disease | denotes | death | MESH:D003643 |
| 51 | 1439-1447 | Species | denotes | patients | Tax:9606 |
| 52 | 1453-1473 | Disease | denotes | SARS-CoV-2 infection | MESH:C000657245 |
| 53 | 1561-1578 | Disease | denotes | myocardial injury | MESH:D009202 |
| 54 | 1597-1605 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 55 | 1606-1615 | Disease | denotes | infection | MESH:D007239 |
| 56 | 1676-1685 | Disease | denotes | mortality | MESH:D003643 |
| 57 | 1689-1709 | Disease | denotes | SARS-CoV-2 infection | MESH:C000657245 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-107 | Sentence | denotes | Myocardial Injury Biomarkers and Cardiac Complications Associated with Mortality in Patients with COVID-19. |
| T2 | 108-218 | Sentence | denotes | Biomarcadores de Lesão Miocárdica e Complicações Cardíacas Associadas à Mortalidade em Pacientes com COVID-19. |
| T3 | 219-336 | Sentence | denotes | BACKGROUND: SARS-CoV-2 is an emerging RNA virus associated with a severe acute respiratory disease known as COVID-19. |
| T4 | 337-441 | Sentence | denotes | Although COVID-19 is predominantly a pulmonary disease, some patients have severe cardiovascular damage. |
| T5 | 442-623 | Sentence | denotes | We performed a quantitative evidence synthesis of clinical data, myocardial injury biomarkers, and cardiac complications associated with in-hospital death in patients with COVID-19. |
| T6 | 624-632 | Sentence | denotes | METHODS: |
| T7 | 633-843 | Sentence | denotes | We searched the databases PubMed, Embase, and Google Scholar to identify studies comparing clinical data, myocardial injury biomarkers, and cardiac complications between non-survivors and survivors of COVID-19. |
| T8 | 844-1018 | Sentence | denotes | Effect sizes were reported as mean difference or standardized mean difference for continuous variables and risk ratio for dichotomous variables with 95% confidence intervals. |
| T9 | 1019-1071 | Sentence | denotes | A random effects model was used to pool the results. |
| T10 | 1072-1080 | Sentence | denotes | RESULTS: |
| T11 | 1081-1194 | Sentence | denotes | Six retrospective studies reporting data from 1,141 patients (832 survivors and 309 non-survivors) were included. |
| T12 | 1195-1474 | Sentence | denotes | We found that underlying cardiovascular conditions; elevation of high-sensitivity cardiac troponin I, N-terminal pro-B-type natriuretic peptide, and creatine kinase-MB; and cardiac complications were associated with increased risk of death for patients with SARS-CoV-2 infection. |
| T13 | 1475-1487 | Sentence | denotes | CONCLUSIONS: |
| T14 | 1488-1821 | Sentence | denotes | The confirmation that underlying cardiovascular conditions, elevation of myocardial injury biomarkers during COVID-19 infection, and acute cardiovascular decompensation are predictors for mortality in SARS-CoV-2 infection must encourage new research to clarify potential mechanisms and test appropriate treatments. (Arq Bras Cardiol. |
| T15 | 1822-1844 | Sentence | denotes | 2020; 115(2):273-277). |
ENG_RE_CONSENSUS
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T0 | 257-260 | CHEBI_33697 | denotes | RNA |
| T1 | 285-291 | HP_0012828 | denotes | severe |
| T2 | 292-297 | HP_0011009 | denotes | acute |
| T17 | 298-317 | HP_0002795 | denotes | respiratory disease |
| T16 | 298-317 | DOID_1579 | denotes | respiratory disease |
| T18 | 327-335 | HP_0033141 | denotes | COVID-19 |
| T4 | 327-335 | DOID_0080600 | denotes | COVID-19 |
| T19 | 346-354 | HP_0033141 | denotes | COVID-19 |
| T5 | 346-354 | DOID_0080600 | denotes | COVID-19 |
| T21 | 374-391 | HP_0002795 | denotes | pulmonary disease |
| T20 | 374-391 | DOID_850 | denotes | pulmonary disease |
| T7 | 412-418 | HP_0012828 | denotes | severe |
| T22 | 419-440 | HP_0001626 | denotes | cardiovascular damage |
| T23 | 507-524 | HP_0001637 | denotes | myocardial injury |
| T24 | 614-622 | HP_0033141 | denotes | COVID-19 |
| T9 | 614-622 | DOID_0080600 | denotes | COVID-19 |
| T27 | 834-842 | HP_0033141 | denotes | COVID-19 |
| T10 | 834-842 | DOID_0080600 | denotes | COVID-19 |
| T25 | 1319-1338 | CHEBI_80233 | denotes | natriuretic peptide |
| T11 | 1344-1352 | CHEBI_16919 | denotes | creatine |
| T26 | 1453-1473 | HP_0033141 | denotes | SARS-CoV-2 infection |
| T12 | 1453-1473 | DOID_0080600 | denotes | SARS-CoV-2 infection |
| T28 | 1597-1605 | HP_0033141 | denotes | COVID-19 |
| T13 | 1597-1605 | DOID_0080600 | denotes | COVID-19 |
| T14 | 1621-1626 | HP_0011009 | denotes | acute |
| T30 | 1627-1656 | HP_0030872 | denotes | cardiovascular decompensation |
| T29 | 1689-1709 | HP_0033141 | denotes | SARS-CoV-2 infection |
| T15 | 1689-1709 | DOID_0080600 | denotes | SARS-CoV-2 infection |
| R11 | T9 | T0 | effect | COVID-19,RNA |
| R14 | T12 | T11 | effect | SARS-CoV-2 infection,creatine |
| R16 | T13 | T11 | no_relation | COVID-19,creatine |
| R18 | T15 | T11 | effect | SARS-CoV-2 infection,creatine |
| R7 | T5 | T0 | no_relation | COVID-19,RNA |
| R5 | T4 | T0 | no_relation | COVID-19,RNA |
| R19 | T2 | T17 | effect | acute,respiratory disease |
| R20 | T1 | T17 | effect | severe,respiratory disease |
| R21 | T1 | T16 | effect | severe,respiratory disease |
| R22 | T2 | T16 | effect | acute,respiratory disease |
| R23 | T7 | T22 | effect | severe,cardiovascular damage |
| R24 | T19 | T22 | effect | COVID-19,cardiovascular damage |
| R25 | T5 | T22 | effect | COVID-19,cardiovascular damage |
| R26 | T18 | T22 | effect | COVID-19,cardiovascular damage |
| R27 | T4 | T22 | effect | COVID-19,cardiovascular damage |
| R28 | T24 | T23 | effect | COVID-19,myocardial injury |
| R29 | T9 | T23 | effect | COVID-19,myocardial injury |
| R30 | T26 | T11 | effect | SARS-CoV-2 infection,creatine |
| R31 | T29 | T11 | effect | SARS-CoV-2 infection,creatine |
| R32 | T28 | T11 | effect | COVID-19,creatine |
| R33 | T13 | T25 | effect | COVID-19,natriuretic peptide |
| R34 | T28 | T25 | effect | COVID-19,natriuretic peptide |
| R35 | T12 | T25 | effect | SARS-CoV-2 infection,natriuretic peptide |
| R36 | T26 | T15 | effect | SARS-CoV-2 infection,SARS-CoV-2 infection |
| R37 | T29 | T25 | effect | SARS-CoV-2 infection,natriuretic peptide |
| R38 | T28 | T30 | effect | COVID-19,cardiovascular decompensation |
| R39 | T13 | T30 | effect | COVID-19,cardiovascular decompensation |
| R40 | T14 | T30 | effect | acute,cardiovascular decompensation |
ENG_NER_NEL_CONSENSUS
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T70 | 1285-1295 | MESH:D019210 | denotes | troponin I |
| T72 | 1319-1338 | CHEBI:80233 | denotes | natriuretic peptide |
| T73 | 1453-1473 | HP:0033141 | denotes | SARS-CoV-2 infection |
| T74 | 327-335 | MESH:D000086382 | denotes | COVID-19 |
| T75 | 614-622 | MESH:D000086382 | denotes | COVID-19 |
| T76 | 834-842 | MESH:D000086382 | denotes | COVID-19 |
| T77 | 834-842 | HP:0033141 | denotes | COVID-19 |
| T78 | 1453-1473 | MESH:D000086382 | denotes | SARS-CoV-2 infection |
| T79 | 1597-1605 | MESH:D000086382 | denotes | COVID-19 |
| T80 | 1597-1605 | HP:0033141 | denotes | COVID-19 |
| T81 | 1368-1389 | MESH:D018376 | denotes | cardiac complications |
| T82 | 1521-1546 | MESH:D018376 | denotes | cardiovascular conditions |
| T83 | 1689-1709 | HP:0033141 | denotes | SARS-CoV-2 infection |
| T84 | 1689-1709 | MESH:D000086382 | denotes | SARS-CoV-2 infection |
| T85 | 1627-1656 | HP:0030872 | denotes | cardiovascular decompensation |
| T86 | 285-317 | MESH:D045169 | denotes | severe acute respiratory disease |
| T87 | 346-354 | MESH:D000086382 | denotes | COVID-19 |
| T88 | 997-1018 | MESH:D016001 | denotes | confidence intervals. |
| T89 | 951-955 | MESH:D012306 | denotes | risk |
| T10 | 346-354 | DOID:0080600 | denotes | COVID-19 |
| T14 | 398-406 | MESH:D010361 | denotes | patients |
| T15 | 412-418 | HP:0012828 | denotes | severe |
| T17 | 525-535 | MESH:D015415 | denotes | biomarkers |
| T19 | 591-596 | MESH:D003643 | denotes | death |
| T20 | 600-608 | MESH:D010361 | denotes | patients |
| T21 | 614-622 | DOID:0080600 | denotes | COVID-19 |
| T23 | 757-767 | MESH:D015415 | denotes | biomarkers |
| T24 | 821-830 | MESH:D017741 | denotes | survivors |
| T25 | 834-842 | DOID:0080600 | denotes | COVID-19 |
| T3 | 257-266 | MESH:D012328 | denotes | RNA virus |
| T30 | 1085-1106 | MESH:D012189 | denotes | retrospective studies |
| T31 | 1133-1141 | MESH:D010361 | denotes | patients |
| T32 | 1147-1156 | MESH:D017741 | denotes | survivors |
| T34 | 1344-1352 | CHEBI:16919 | denotes | creatine |
| T35 | 1344-1352 | MESH:D003401 | denotes | creatine |
| T37 | 1421-1425 | MESH:D012306 | denotes | risk |
| T39 | 1429-1434 | MESH:D003643 | denotes | death |
| T4 | 285-291 | HP:0012828 | denotes | severe |
| T40 | 1439-1447 | MESH:D010361 | denotes | patients |
| T42 | 1453-1473 | DOID:0080600 | denotes | SARS-CoV-2 infection |
| T44 | 1579-1589 | MESH:D015415 | denotes | biomarkers |
| T45 | 1597-1605 | DOID:0080600 | denotes | COVID-19 |
| T48 | 1621-1626 | HP:0011009 | denotes | acute |
| T49 | 1676-1685 | MESH:D009026 | denotes | mortality |
| T5 | 292-297 | HP:0011009 | denotes | acute |
| T51 | 1689-1709 | DOID:0080600 | denotes | SARS-CoV-2 infection |
| T53 | 1729-1737 | MESH:D012106 | denotes | research |
| T54 | 257-260 | CHEBI:33697 | denotes | RNA |
| T55 | 231-241 | MESH:D000086402 | denotes | SARS-CoV-2 |
| T58 | 298-317 | DOID:1579 | denotes | respiratory disease |
| T59 | 327-335 | DOID:0080600 | denotes | COVID-19 |
| T61 | 298-317 | HP:0002795 | denotes | respiratory disease |
| T62 | 327-335 | HP:0033141 | denotes | COVID-19 |
| T63 | 346-354 | HP:0033141 | denotes | COVID-19 |
| T64 | 374-391 | DOID:850 | denotes | pulmonary disease |
| T65 | 374-391 | HP:0002795 | denotes | pulmonary disease |
| T66 | 374-391 | MESH:D008171 | denotes | pulmonary disease |
| T67 | 419-440 | HP:0001626 | denotes | cardiovascular damage |
| T68 | 507-524 | HP:0001637 | denotes | myocardial injury |
| T69 | 614-622 | HP:0033141 | denotes | COVID-19 |