PubMed:32736597 / 1913-2734 JSONTXT

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{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T4","span":{"begin":268,"end":273},"obj":"Body_part"},{"id":"T5","span":{"begin":307,"end":312},"obj":"Body_part"},{"id":"T6","span":{"begin":346,"end":351},"obj":"Body_part"},{"id":"T7","span":{"begin":393,"end":400},"obj":"Body_part"},{"id":"T8","span":{"begin":508,"end":514},"obj":"Body_part"},{"id":"T9","span":{"begin":647,"end":653},"obj":"Body_part"}],"attributes":[{"id":"A4","pred":"fma_id","subj":"T4","obj":"http://purl.org/sig/ont/fma/fma7088"},{"id":"A5","pred":"fma_id","subj":"T5","obj":"http://purl.org/sig/ont/fma/fma7088"},{"id":"A6","pred":"fma_id","subj":"T6","obj":"http://purl.org/sig/ont/fma/fma7088"},{"id":"A7","pred":"fma_id","subj":"T7","obj":"http://purl.org/sig/ont/fma/fma82743"},{"id":"A8","pred":"fma_id","subj":"T8","obj":"http://purl.org/sig/ont/fma/fma7203"},{"id":"A9","pred":"fma_id","subj":"T9","obj":"http://purl.org/sig/ont/fma/fma264279"}],"text":"All subjects must be aged ≥18 years, male or female, must be willing and able to give informed consent and must not have any contraindications to take hydroxychloroquine (intolerance or previous toxicity for hydroxychloroquine/chloroquine, bradycardia or reduction in heart rhythm with arrhythmia, ischemic heart disease, retinopathy, congestive heart failure with use of diuretics, favism or glucose-6-phosphate dehydrogenase (G6PD) deficiency, diabetes type 1, major comorbidities such as advanced chronic kidney disease or dialysis therapy, known history of ventricular arrhythmia, any oncologic/hematologic malignancy, severe neurological and mental illness, current use of medications with known significant drug-drug interactions, and known prolonged QT syndrome or current use of drugs with known QT prolongation)."}

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{"project":"LitCovid-PD-CLO","denotations":[{"id":"T21","span":{"begin":27,"end":29},"obj":"http://purl.obolibrary.org/obo/CLO_0050510"},{"id":"T22","span":{"begin":37,"end":41},"obj":"http://purl.obolibrary.org/obo/UBERON_0003101"},{"id":"T23","span":{"begin":37,"end":41},"obj":"http://www.ebi.ac.uk/efo/EFO_0000970"},{"id":"T24","span":{"begin":45,"end":51},"obj":"http://purl.obolibrary.org/obo/UBERON_0003100"},{"id":"T25","span":{"begin":268,"end":273},"obj":"http://purl.obolibrary.org/obo/UBERON_0000948"},{"id":"T26","span":{"begin":268,"end":273},"obj":"http://purl.obolibrary.org/obo/UBERON_0007100"},{"id":"T27","span":{"begin":268,"end":273},"obj":"http://purl.obolibrary.org/obo/UBERON_0015228"},{"id":"T28","span":{"begin":268,"end":273},"obj":"http://www.ebi.ac.uk/efo/EFO_0000815"},{"id":"T29","span":{"begin":307,"end":312},"obj":"http://purl.obolibrary.org/obo/UBERON_0000948"},{"id":"T30","span":{"begin":307,"end":312},"obj":"http://purl.obolibrary.org/obo/UBERON_0007100"},{"id":"T31","span":{"begin":307,"end":312},"obj":"http://purl.obolibrary.org/obo/UBERON_0015228"},{"id":"T32","span":{"begin":307,"end":312},"obj":"http://www.ebi.ac.uk/efo/EFO_0000815"},{"id":"T33","span":{"begin":346,"end":351},"obj":"http://purl.obolibrary.org/obo/UBERON_0000948"},{"id":"T34","span":{"begin":346,"end":351},"obj":"http://purl.obolibrary.org/obo/UBERON_0007100"},{"id":"T35","span":{"begin":346,"end":351},"obj":"http://purl.obolibrary.org/obo/UBERON_0015228"},{"id":"T36","span":{"begin":346,"end":351},"obj":"http://www.ebi.ac.uk/efo/EFO_0000815"},{"id":"T37","span":{"begin":508,"end":514},"obj":"http://purl.obolibrary.org/obo/UBERON_0002113"},{"id":"T38","span":{"begin":508,"end":514},"obj":"http://www.ebi.ac.uk/efo/EFO_0000927"},{"id":"T39","span":{"begin":508,"end":514},"obj":"http://www.ebi.ac.uk/efo/EFO_0000929"}],"text":"All subjects must be aged ≥18 years, male or female, must be willing and able to give informed consent and must not have any contraindications to take hydroxychloroquine (intolerance or previous toxicity for hydroxychloroquine/chloroquine, bradycardia or reduction in heart rhythm with arrhythmia, ischemic heart disease, retinopathy, congestive heart failure with use of diuretics, favism or glucose-6-phosphate dehydrogenase (G6PD) deficiency, diabetes type 1, major comorbidities such as advanced chronic kidney disease or dialysis therapy, known history of ventricular arrhythmia, any oncologic/hematologic malignancy, severe neurological and mental illness, current use of medications with known significant drug-drug interactions, and known prolonged QT syndrome or current use of drugs with known QT prolongation)."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T13","span":{"begin":37,"end":41},"obj":"Chemical"},{"id":"T14","span":{"begin":151,"end":169},"obj":"Chemical"},{"id":"T15","span":{"begin":208,"end":226},"obj":"Chemical"},{"id":"T16","span":{"begin":227,"end":238},"obj":"Chemical"},{"id":"T17","span":{"begin":372,"end":381},"obj":"Chemical"},{"id":"T18","span":{"begin":393,"end":400},"obj":"Chemical"},{"id":"T20","span":{"begin":403,"end":412},"obj":"Chemical"},{"id":"T24","span":{"begin":713,"end":717},"obj":"Chemical"},{"id":"T25","span":{"begin":718,"end":722},"obj":"Chemical"},{"id":"T26","span":{"begin":787,"end":792},"obj":"Chemical"}],"attributes":[{"id":"A13","pred":"chebi_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/CHEBI_30780"},{"id":"A14","pred":"chebi_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/CHEBI_5801"},{"id":"A15","pred":"chebi_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/CHEBI_5801"},{"id":"A16","pred":"chebi_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/CHEBI_3638"},{"id":"A17","pred":"chebi_id","subj":"T17","obj":"http://purl.obolibrary.org/obo/CHEBI_35498"},{"id":"A18","pred":"chebi_id","subj":"T18","obj":"http://purl.obolibrary.org/obo/CHEBI_17234"},{"id":"A19","pred":"chebi_id","subj":"T18","obj":"http://purl.obolibrary.org/obo/CHEBI_4167"},{"id":"A20","pred":"chebi_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/CHEBI_18367"},{"id":"A21","pred":"chebi_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/CHEBI_26020"},{"id":"A22","pred":"chebi_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/CHEBI_35780"},{"id":"A23","pred":"chebi_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/CHEBI_43474"},{"id":"A24","pred":"chebi_id","subj":"T24","obj":"http://purl.obolibrary.org/obo/CHEBI_23888"},{"id":"A25","pred":"chebi_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/CHEBI_23888"},{"id":"A26","pred":"chebi_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/CHEBI_23888"}],"text":"All subjects must be aged ≥18 years, male or female, must be willing and able to give informed consent and must not have any contraindications to take hydroxychloroquine (intolerance or previous toxicity for hydroxychloroquine/chloroquine, bradycardia or reduction in heart rhythm with arrhythmia, ischemic heart disease, retinopathy, congestive heart failure with use of diuretics, favism or glucose-6-phosphate dehydrogenase (G6PD) deficiency, diabetes type 1, major comorbidities such as advanced chronic kidney disease or dialysis therapy, known history of ventricular arrhythmia, any oncologic/hematologic malignancy, severe neurological and mental illness, current use of medications with known significant drug-drug interactions, and known prolonged QT syndrome or current use of drugs with known QT prolongation)."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T6","span":{"begin":274,"end":280},"obj":"http://purl.obolibrary.org/obo/GO_0048511"}],"text":"All subjects must be aged ≥18 years, male or female, must be willing and able to give informed consent and must not have any contraindications to take hydroxychloroquine (intolerance or previous toxicity for hydroxychloroquine/chloroquine, bradycardia or reduction in heart rhythm with arrhythmia, ischemic heart disease, retinopathy, congestive heart failure with use of diuretics, favism or glucose-6-phosphate dehydrogenase (G6PD) deficiency, diabetes type 1, major comorbidities such as advanced chronic kidney disease or dialysis therapy, known history of ventricular arrhythmia, any oncologic/hematologic malignancy, severe neurological and mental illness, current use of medications with known significant drug-drug interactions, and known prolonged QT syndrome or current use of drugs with known QT prolongation)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T15","span":{"begin":0,"end":821},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"All subjects must be aged ≥18 years, male or female, must be willing and able to give informed consent and must not have any contraindications to take hydroxychloroquine (intolerance or previous toxicity for hydroxychloroquine/chloroquine, bradycardia or reduction in heart rhythm with arrhythmia, ischemic heart disease, retinopathy, congestive heart failure with use of diuretics, favism or glucose-6-phosphate dehydrogenase (G6PD) deficiency, diabetes type 1, major comorbidities such as advanced chronic kidney disease or dialysis therapy, known history of ventricular arrhythmia, any oncologic/hematologic malignancy, severe neurological and mental illness, current use of medications with known significant drug-drug interactions, and known prolonged QT syndrome or current use of drugs with known QT prolongation)."}

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{"project":"LitCovid-PD-HP","denotations":[{"id":"T1","span":{"begin":240,"end":251},"obj":"Phenotype"},{"id":"T2","span":{"begin":286,"end":296},"obj":"Phenotype"},{"id":"T3","span":{"begin":322,"end":333},"obj":"Phenotype"},{"id":"T4","span":{"begin":335,"end":359},"obj":"Phenotype"},{"id":"T5","span":{"begin":500,"end":522},"obj":"Phenotype"},{"id":"T6","span":{"begin":561,"end":583},"obj":"Phenotype"}],"attributes":[{"id":"A1","pred":"hp_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/HP_0001662"},{"id":"A2","pred":"hp_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/HP_0011675"},{"id":"A3","pred":"hp_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/HP_0000488"},{"id":"A4","pred":"hp_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/HP_0001635"},{"id":"A5","pred":"hp_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/HP_0012622"},{"id":"A6","pred":"hp_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/HP_0004308"}],"text":"All subjects must be aged ≥18 years, male or female, must be willing and able to give informed consent and must not have any contraindications to take hydroxychloroquine (intolerance or previous toxicity for hydroxychloroquine/chloroquine, bradycardia or reduction in heart rhythm with arrhythmia, ischemic heart disease, retinopathy, congestive heart failure with use of diuretics, favism or glucose-6-phosphate dehydrogenase (G6PD) deficiency, diabetes type 1, major comorbidities such as advanced chronic kidney disease or dialysis therapy, known history of ventricular arrhythmia, any oncologic/hematologic malignancy, severe neurological and mental illness, current use of medications with known significant drug-drug interactions, and known prolonged QT syndrome or current use of drugs with known QT prolongation)."}

{"project":"hydroxychloroquine","denotations":[{"id":"T1","span":{"begin":240,"end":251},"obj":"Phenotype"},{"id":"T2","span":{"begin":286,"end":296},"obj":"Phenotype"},{"id":"T3","span":{"begin":322,"end":333},"obj":"Phenotype"},{"id":"T4","span":{"begin":335,"end":359},"obj":"Phenotype"},{"id":"T5","span":{"begin":500,"end":522},"obj":"Phenotype"},{"id":"T6","span":{"begin":561,"end":583},"obj":"Phenotype"}],"attributes":[{"id":"A1","pred":"hp_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/HP_0001662"},{"id":"A2","pred":"hp_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/HP_0011675"},{"id":"A3","pred":"hp_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/HP_0000488"},{"id":"A4","pred":"hp_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/HP_0001635"},{"id":"A5","pred":"hp_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/HP_0012622"},{"id":"A6","pred":"hp_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/HP_0004308"}],"text":"All subjects must be aged ≥18 years, male or female, must be willing and able to give informed consent and must not have any contraindications to take hydroxychloroquine (intolerance or previous toxicity for hydroxychloroquine/chloroquine, bradycardia or reduction in heart rhythm with arrhythmia, ischemic heart disease, retinopathy, congestive heart failure with use of diuretics, favism or glucose-6-phosphate dehydrogenase (G6PD) deficiency, diabetes type 1, major comorbidities such as advanced chronic kidney disease or dialysis therapy, known history of ventricular arrhythmia, any oncologic/hematologic malignancy, severe neurological and mental illness, current use of medications with known significant drug-drug interactions, and known prolonged QT syndrome or current use of drugs with known QT prolongation)."}